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Aliases for SLFNL1 Gene

Aliases for SLFNL1 Gene

  • Schlafen-Like 1 2 3

External Ids for SLFNL1 Gene

Previous GeneCards Identifiers for SLFNL1 Gene

  • GC01M041253
  • GC01M041481
  • GC01M039598

Summaries for SLFNL1 Gene

GeneCards Summary for SLFNL1 Gene

SLFNL1 (Schlafen-Like 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLFNL1 Gene

Genomics for SLFNL1 Gene

Regulatory Elements for SLFNL1 Gene

Genomic Location for SLFNL1 Gene

Start:
41,015,597 bp from pter
End:
41,023,444 bp from pter
Size:
7,848 bases
Orientation:
Minus strand

Genomic View for SLFNL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLFNL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLFNL1 Gene

Proteins for SLFNL1 Gene

  • Protein details for SLFNL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q499Z3-SLNL1_HUMAN
    Recommended name:
    Schlafen-like protein 1
    Protein Accession:
    Q499Z3
    Secondary Accessions:
    • A8K8D1
    • Q49AG8
    • Q5VW72
    • Q5VW74
    • Q8N7V7
    • Q8TCH6
    • Q8WVZ8

    Protein attributes for SLFNL1 Gene

    Size:
    407 amino acids
    Molecular mass:
    45603 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLFNL1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLFNL1 Gene

Proteomics data for SLFNL1 Gene at MOPED

Post-translational modifications for SLFNL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLFNL1 Gene

No data available for DME Specific Peptides for SLFNL1 Gene

Domains for SLFNL1 Gene

Protein Domains for SLFNL1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLFNL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q499Z3

UniProtKB/Swiss-Prot:

SLNL1_HUMAN :
  • Q499Z3
Family:
  • Belongs to the Schlafen family.
genes like me logo Genes that share domains with SLFNL1: view

No data available for Gene Families for SLFNL1 Gene

Function for SLFNL1 Gene

Gene Ontology (GO) - Molecular Function for SLFNL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with SLFNL1: view

Phenotypes for SLFNL1 Gene

GenomeRNAi human phenotypes for SLFNL1:
genes like me logo Genes that share phenotypes with SLFNL1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLFNL1 Gene

Localization for SLFNL1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLFNL1 Gene COMPARTMENTS Subcellular localization image for SLFNL1 gene
Compartment Confidence
nucleus 2
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for SLFNL1 Gene

Pathways for SLFNL1 Gene

SuperPathways for SLFNL1 Gene

No Data Available

Interacting Proteins for SLFNL1 Gene

Gene Ontology (GO) - Biological Process for SLFNL1 Gene

None

No data available for Pathways by source for SLFNL1 Gene

Transcripts for SLFNL1 Gene

Unigene Clusters for SLFNL1 Gene

Schlafen-like 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLFNL1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLFNL1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6 ^ 7
SP1: - -
SP2:
SP3:
SP4: - -
SP5: -
SP6: -
SP7: -
SP8: -

Relevant External Links for SLFNL1 Gene

GeneLoc Exon Structure for
SLFNL1
ECgene alternative splicing isoforms for
SLFNL1

Expression for SLFNL1 Gene

mRNA expression in normal human tissues for SLFNL1 Gene

mRNA differential expression in normal tissues according to GTEx for SLFNL1 Gene

This gene is overexpressed in Testis (27.3).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SLFNL1 Gene

SOURCE GeneReport for Unigene cluster for SLFNL1 Gene Hs.194609

genes like me logo Genes that share expressions with SLFNL1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SLFNL1 Gene

Orthologs for SLFNL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLFNL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLFNL1 35
  • 99.02 (n)
  • 99.26 (a)
SLFNL1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLFNL1 35
  • 78.18 (n)
  • 72.75 (a)
SLFNL1 36
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLFNL1 35
  • 79.3 (n)
  • 70.16 (a)
SLFNL1 36
  • 70 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slfnl1 35
  • 78.16 (n)
  • 73.65 (a)
Slfnl1 16
Slfnl1 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLFNL1 36
  • 38 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 64 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Slfnl1 35
  • 77.48 (n)
  • 73.22 (a)
lizard
(Anolis carolinensis)
Reptilia SLFNL1 36
  • 49 (a)
OneToOne
Species with no ortholog for SLFNL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SLFNL1 Gene

ENSEMBL:
Gene Tree for SLFNL1 (if available)
TreeFam:
Gene Tree for SLFNL1 (if available)

Paralogs for SLFNL1 Gene

No data available for Paralogs for SLFNL1 Gene

Variants for SLFNL1 Gene

Sequence variations from dbSNP and Humsavar for SLFNL1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
VAR_031459 -
VAR_031460 -
VAR_031461 -

Relevant External Links for SLFNL1 Gene

HapMap Linkage Disequilibrium report
SLFNL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SLFNL1 Gene

Disorders for SLFNL1 Gene

No disorders were found for SLFNL1 Gene.

No data available for UniProtKB/Swiss-Prot for SLFNL1 Gene

Publications for SLFNL1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for SLFNL1 Gene

Sources for SLFNL1 Gene

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