Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SLCO6A1 Gene

protein-coding   GIFtS: 50
GCID: GC05M101735

Solute Carrier Organic Anion Transporter Family, Member...

  Search for SLCO6A1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Solute Carrier Organic Anion Transporter Family, Member 6A11 2     CT482 3
Cancer/Testis Antigen 481 2 3     OATP-I2 3
GST2 3 5     OATP6A12 3
Gonad-Specific Transporter2 3     OATPY2
Organic Anion-Transporting Polypeptide 6A12 3     Solute Carrier Organic Anion Transporter Family Member 6A12
Organic Anion-Transporting Polypeptide I2 3     Testis-Specific Organic Anion Transporter2
Solute Carrier Family 21 Member 192 3     SLC21A193

External Ids:    HGNC: 236131   Entrez Gene: 1334822   Ensembl: ENSG000002053597   OMIM: 6133655   UniProtKB: Q86UG43   

Export aliases for SLCO6A1 gene to outside databases

Previous GC identifers: GC05M101783 GC05M096889


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for SLCO6A1 Gene:
SLCO6A1 (solute carrier organic anion transporter family, member 6A1) is a protein-coding gene. GO annotations related to this gene include transporter activity. An important paralog of this gene is SLCO2A1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000005.10  NT_034772.7  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLCO6A1 gene promoter:
         Max1   GR   C/EBPbeta   POU6F1 (c2)   STAT5A   AREB6   Max   GR-alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLCO6A1 promoter sequence
   Search Chromatin IP Primers for SLCO6A1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLCO6A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q21.1   Ensembl cytogenetic band:  5q21.1   HGNC cytogenetic band: 5q21.2

SLCO6A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLCO6A1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M101735:  view genomic region     (about GC identifiers)

Start:
101,707,486 bp from pter      End:
101,834,720 bp from pter
Size:
127,235 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SO6A1_HUMAN, Q86UG4 (See protein sequence)
Recommended Name: Solute carrier organic anion transporter family member 6A1  
Size: 719 amino acids; 79232 Da
Secondary accessions: A6NHC1 Q6ZMY5 Q86UV2 Q8IYU5
Alternative splicing: 3 isoforms:  Q86UG4-1   Q86UG4-2   Q86UG4-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLCO6A1: NX_Q86UG4

Explore proteomics data for SLCO6A1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn300, Asn497, Asn546, Asn661
  • Modification sites at PhosphoSitePlus

  • See SLCO6A1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001275931.1  NP_001275933.1  NP_775759.3  

    ENSEMBL proteins: 
     ENSP00000421339   ENSP00000421846   ENSP00000369135   ENSP00000373671   ENSP00000421990  
     ENSP00000369138  

    SLCO6A1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SLCO6A1
    GenScript Custom Purified and Recombinant Proteins Services for SLCO6A1
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLCO6A1

     
    Search eBioscience for Proteins for SLCO6A1 

    SLCO6A1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SLCO6A1
    Novus Biologicals SLCO6A1 Antibodies
    Abcam antibodies for SLCO6A1
    Cloud-Clone Corp. Antibodies for SLCO6A1
    ThermoFisher Antibodies for SLCO6A1
    LSBio Antibodies in human, mouse, rat for SLCO6A1

    SLCO6A1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SLCO6A1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SLCO6A1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SLCO6A1
    Cloud-Clone Corp. CLIAs for SLCO6A1
    Search eBioscience for ELISAs for SLCO6A1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: OATP6A1
    SLCO family of organic anion transporting polypeptides

    3 InterPro protein domains:
     IPR002350 Kazal_dom
     IPR004156 OA_transporter
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q86UG4

    ProtoNet protein and cluster: Q86UG4

    2 Blocks protein domains:
    IPB004156 Organic anion transporter polypeptide (OATP)
    IPB011497 Protease inhibitor


    UniProtKB/Swiss-Prot: SO6A1_HUMAN, Q86UG4
    Similarity: Belongs to the organo anion transporter (TC 2.A.60) family
    Similarity: Contains 1 Kazal-like domain


    Find genes that share domains with SLCO6A1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0005515protein binding ----
         
    Find genes that share ontologies with SLCO6A1           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLCO6A1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SLCO6A1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLCO6A1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLCO6A1

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SLCO6A1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SLCO6A1:
    hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmidSLCO6A1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SLCO6A1
    Predesigned siRNA for gene silencing in human, mouse, rat SLCO6A1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SLCO6A1

    Clone
    Products:
         
    OriGene clones in human, mouse for SLCO6A1 (see all 6)
    OriGene ORF clones in mouse, rat for SLCO6A1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLCO6A1 (NM_173488)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLCO6A1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLCO6A1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SLCO6A1
    Browse ESI BIO Cell Lines and PureStem Progenitors for SLCO6A1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLCO6A1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SO6A1_HUMAN, Q86UG4: Cell membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SLCO6A1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLCO6A1
    Interactions:

        GeneGlobe Interaction Network for SLCO6A1

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0055085transmembrane transport ----

    Find genes that share ontologies with SLCO6A1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLCO6A1 (SO6A1)

    2 Novoseek inferred chemical compound relationships for SLCO6A1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    thyroxine 33 1 12923172 (1)
    methotrexate 26.4 2 11532100 (1), 11375950 (1)



    Find genes that share compounds with SLCO6A1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SLCO6A1 gene (3 alternative transcripts): 
    NM_001289002.1  NM_001289004.1  NM_173488.4  

    Unigene Cluster for SLCO6A1:

    Solute carrier organic anion transporter family, member 6A1
    Hs.388874  [show with all ESTs]
    Unigene Representative Sequence: NM_173488
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000506729(uc003knn.3 uc003knp.3) ENST00000511588 ENST00000514765
    ENST00000379807 ENST00000389019(uc003kno.3 uc003knq.3) ENST00000513675
    ENST00000514551 ENST00000505739 ENST00000505407 ENST00000379810
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SLCO6A1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate SLCO6A1:
    hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmidSLCO6A1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SLCO6A1
    Predesigned siRNA for gene silencing in human, mouse, rat SLCO6A1
    Clone
    Products:
         
    OriGene clones in human, mouse for SLCO6A1 (see all 6)
    OriGene ORF clones in mouse, rat for SLCO6A1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLCO6A1 (NM_173488)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLCO6A1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLCO6A1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SLCO6A1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLCO6A1
      QuantiTect SYBR Green Assays in human, mouse, rat SLCO6A1
      QuantiFast Probe-based Assays in human, mouse, rat SLCO6A1

    Additional mRNA sequence: 

    AF505657.1 AK131445.1 AY273897.1 BC034976.2 

    4 DOTS entries:

    DT.100750030  DT.40205095  DT.102821397  DT.95079143 

    14 AceView cDNA sequences:

    AA383531 AL040864 BI826682 AL042741 AY273897 CD557255 AK131445 BM554439 
    NM_173488 BC034976 AF505657 BG705215 BG772379 BI461904 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SLCO6A1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTCCAAAC
    SLCO6A1 Expression
    About this image

    SLCO6A1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLCO6A1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.388874

    UniProtKB/Swiss-Prot: SO6A1_HUMAN, Q86UG4
    Tissue specificity: Strongly expressed in testis. Weakly expressed in spleen, brain, fetal brain and placenta.
    Detected in lung tumors

        Custom PCR Arrays for SLCO6A1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SLCO6A1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLCO6A1
    QuantiTect SYBR Green Assays in human, mouse, rat SLCO6A1
    QuantiFast Probe-based Assays in human, mouse, rat SLCO6A1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLCO6A1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for SLCO6A1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slco6b11 , 5 solute carrier organic anion transporter family, member more1, 5 66.24(n)1
    50(a)1
      1 (47.76 cM)5
    678541  NM_001039475.11  NP_001034564.11 
     969061765 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    37(a)
    1 → many
    Z(50079798-50109297)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    29(a)
    1 → many
    GL343193.1(1248811-1292627)
    fruit fly
    (Drosophila melanogaster)
    Insecta Oatp58Db6
    Organic anion transporting polypeptide 58Db
    16(a)
    many ↔ many
    2R(18108685-18111095)
    worm
    (Caenorhabditis elegans)
    Secernentea Y70G10A.36
    K02G10.56
    (see all 3)
    Protein K02G10.5 (K02G10.5) mRNA, complete cds
    (see all 3)
    23(a)
    22(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    III(10238672-10244438) WBGene00013499
    X(4687788-4691316) WBGene00019346


    ENSEMBL Gene Tree for SLCO6A1 (if available)
    TreeFam Gene Tree for SLCO6A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SLCO6A1 gene
    SLCO2A12  SLCO4C12  SLCO1B72  ENSG000002570622  SLCO1B32  SLCO3A12  SLCO2B12  SLCO5A12  
    SLCO1B12  SLCO1A22  ENSG000002570462  SLCO4A12  SLCO1C12  
    6 SIMAP similar genes for SLCO6A1 using alignment to 4 protein entries:     SO6A1_HUMAN (see all proteins):
    DKFZp313M176    SLCO4C1    SLCO4A1    SLCO1B3    SLCO2A1    SLCO3A1

    Find genes that share paralogs with SLCO6A1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SLCO6A1 (see all 2597)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs100541491,2
    C,F,A,H--101707293(+) TCTGTT/AATAGC 1 -- int112Minor allele frequency- A:0.43NS EA WA NA CSA 782
    rs1876276781,2
    --101707308(+) ATCTAC/TATTTA 1 -- int10--------
    rs100557531,2
    C,F,A,H--101707342(+) CCCAAC/TCCATA 1 -- int117Minor allele frequency- T:0.42NS EA WA CSA NA 2338
    rs1163176121,2
    F--101707373(+) GATTTA/GTTTTC 1 -- int11Minor allele frequency- G:0.03NA 120
    rs678329631,2
    C--101707427(+) TCTAT-/ACACACA 1 -- int10--------
    rs1445719051,2
    C--101707559(+) TATTAA/GGAAGA 1 -- int10--------
    rs1930642531,2
    --101707721(+) AAACAC/TAATGT 1 -- ut310--------
    rs1385936581,2
    --101707747(+) TGAAAC/GTTGGG 1 -- ut310--------
    rs623693021,2
    C--101707793(+) AACTCG/CTTTTC 1 -- ut314Minor allele frequency- C:0.17NA WA EA 360
    rs1161777261,2
    C,F--101707802(+) TCACAC/TTCTGA 1 -- ut311Minor allele frequency- T:0.03NA 120

    HapMap Linkage Disequilibrium report for SLCO6A1 (101707486 - 101834720 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SLCO6A1 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2730529CNV Deletion23290073
    esv2730527CNV Deletion23290073
    esv1929846CNV Deletion18987734
    esv2730530CNV Deletion23290073
    esv2730531CNV Deletion23290073
    esv2730532CNV Deletion23290073
    nsv882517CNV Loss21882294
    nsv882510CNV Loss21882294
    nsv522882CNV Loss19592680
    nsv462325CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLCO6A1
    DNA2.0 Custom Variant and Variant Library Synthesis for SLCO6A1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613365    OMIM disorders: --


    Find genes that share disorders with SLCO6A1           About GenesLikeMe

    Genetic Association Database (GAD): SLCO6A1
    Human Genome Epidemiology (HuGE) Navigator: SLCO6A1 (4 documents)

    Export disorders for SLCO6A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SLCO6A1 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with SLCO6A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388)1, 4 Kenny E.E....Peter I. (PLoS Genet. 2012)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Genetic polymorphisms in Thai neonates with hyperbilirubinemia. (PubMed id 19397531)1, 4 Prachukthum S....Hongeng S. (Acta Paediatr. 2009)
    4. Common variants conferring risk of schizophrenia. (PubMed id 19571808)1, 4 Stefansson H....Collier D.A. (Nature 2009)
    5. Identification and characterization of novel rat and human gonad- specific organic anion transporters. (PubMed id 12677006)1, 2 Suzuki T.... Abe T. (Mol. Endocrinol. 2003)
    6. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PubMed id 23974872)1 Ripke S....Sullivan P.F. (Nat. Genet. 2013)
    7. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (BMC Med. Genet. 2007)
    8. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PubMed id 17903296)4 Kiel D.P....Karasik D. (BMC Med. Genet. 2007)
    9. Identification of the gonad-specific anion transporter SLCO6A1 as a cancer/testis (CT) antigen expressed in human lung cancer. (PubMed id 15546177)2 Lee S.-Y.... Old L.J. (Cancer Immun. 2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 133482 HGNC: 23613 AceView: SLCO6A1 Ensembl:ENSG00000205359 euGenes: HUgn133482
    ECgene: SLCO6A1 H-InvDB: SLCO6A1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SLCO6A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SLCO6A1 gene:
    Search GeneIP for patents involving SLCO6A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SLCO6A1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SLCO6A1  
     OriGene qSTAR qPCR primer pairs in human, mouse for SLCO6A1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SLCO6A1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SLCO6A1   OriGene Custom Protein Services for SLCO6A1  

     
     
     Block miRNA regulation of human, mouse, rat SLCO6A1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SLCO6A1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLCO6A1 Predesigned siRNA for gene silencing in human, mouse, rat SLCO6A1
     QuantiFast Probe-based Assays in human, mouse, rat SLCO6A1 QuantiTect SYBR Green Assays in human, mouse, rat SLCO6A1
     Custom PCR Arrays for SLCO6A1 Search Chromatin IP Primers for SLCO6A1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLCO6A1  GeneGlobe Interaction Network for SLCO6A1
     Regulatory tfbs in SLCO6A1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for SLCO6A1 GenScript cDNA clones with any tag delivered in your preferred vector for SLCO6A1
     GenScript Custom Assay Services for SLCO6A1 GenScript Custom overexpressing Cell Line Services for SLCO6A1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SLCO6A1 (SO6A1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SLCO6A1 antibodies
     Antibodies for SLCO6A1
     See all of Abcam's Antibodies, Kits and Proteins for SLCO6A1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SLCO6A1
     Antibodies for SLCO6A1
     ELISAs for SLCO6A1
     CLIAs for SLCO6A1



     Browse ESI BIO Cell Lines and PureStem Progenitors for SLCO6A1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLCO6A1
     SwitchGear 3'UTR luciferase reporter plasmids for SLCO6A1
     SwitchGear Promoter luciferase reporter plasmids for SLCO6A1
     ThermoFisher Antibodies for SLCO6A1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLCO6A1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLCO6A1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SLCO6A1
     LSBio Antibodies in human, mouse, rat for SLCO6A1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for SLCO6A1
      Search eBioscience for proteins for SLCO6A1
      Search eBioscience for elisas for SLCO6A1
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SLCO6A1 gene at Home site.
    Version: 3.12.202 14 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4