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Aliases for SLCO1B7 Gene

Aliases for SLCO1B7 Gene

  • Solute Carrier Organic Anion Transporter Family Member 1B7 (Putative) 2 3
  • Solute Carrier Organic Anion Transporter Family Member 1B7 (Non-Functional) 2 3 5
  • Solute Carrier Organic Anion Transporter Family, Member 1B7 (Non-Functional) 2 3
  • Liver-Specific Organic Anion Transporter 3 3 4
  • LST-3 3 4
  • LST3 3 4
  • Liver-Specific Organic Anion Transporter 3TM12 3
  • Organic Anion Transporter LST-3b 3
  • LST-3TM12 3
  • SLC21A21 3
  • LST3TM12 4

External Ids for SLCO1B7 Gene

Previous GeneCards Identifiers for SLCO1B7 Gene

  • GC12P021169
  • GC12P020969
  • GC12P020970
  • GC12P020975
  • GC12P020980

Summaries for SLCO1B7 Gene

GeneCards Summary for SLCO1B7 Gene

SLCO1B7 (Solute Carrier Organic Anion Transporter Family Member 1B7 (Putative)) is a Protein Coding gene. Among its related pathways are Bile secretion. GO annotations related to this gene include transporter activity and transmembrane transporter activity. An important paralog of this gene is ENSG00000257046.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLCO1B7 Gene

Genomics for SLCO1B7 Gene

Regulatory Elements for SLCO1B7 Gene

Enhancers for SLCO1B7 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SLCO1B7 on UCSC Golden Path with GeneCards custom track

Genomic Location for SLCO1B7 Gene

21,015,696 bp from pter
21,092,745 bp from pter
77,050 bases
Plus strand

Genomic View for SLCO1B7 Gene

Genes around SLCO1B7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLCO1B7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLCO1B7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLCO1B7 Gene

Proteins for SLCO1B7 Gene

  • Protein details for SLCO1B7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative solute carrier organic anion transporter family member 1B7
    Protein Accession:
    Secondary Accessions:
    • Q71QF0

    Protein attributes for SLCO1B7 Gene

    640 amino acids
    Molecular mass:
    71247 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLCO1B7 Gene

Proteomics data for SLCO1B7 Gene at MOPED

Post-translational modifications for SLCO1B7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLCO1B7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLCO1B7 Gene

Domains & Families for SLCO1B7 Gene

Gene Families for SLCO1B7 Gene

Protein Domains for SLCO1B7 Gene


Graphical View of Domain Structure for InterPro Entry



  • Contains 1 Kazal-like domain.
  • Belongs to the organo anion transporter (TC 2.A.60) family.
  • Contains 1 Kazal-like domain.
  • Belongs to the organo anion transporter (TC 2.A.60) family.
genes like me logo Genes that share domains with SLCO1B7: view

No data available for Suggested Antigen Peptide Sequences for SLCO1B7 Gene

Function for SLCO1B7 Gene

genes like me logo Genes that share phenotypes with SLCO1B7: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLCO1B7 Gene

Localization for SLCO1B7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLCO1B7 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLCO1B7 Gene COMPARTMENTS Subcellular localization image for SLCO1B7 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for SLCO1B7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLCO1B7: view

Pathways & Interactions for SLCO1B7 Gene

SuperPathways for SLCO1B7 Gene

Superpath Contained pathways
1 Bile secretion
genes like me logo Genes that share pathways with SLCO1B7: view

Pathways by source for SLCO1B7 Gene

1 KEGG pathway for SLCO1B7 Gene

Interacting Proteins for SLCO1B7 Gene

Gene Ontology (GO) - Biological Process for SLCO1B7 Gene


No data available for SIGNOR curated interactions for SLCO1B7 Gene

Drugs & Compounds for SLCO1B7 Gene

No Compound Related Data Available

Transcripts for SLCO1B7 Gene

mRNA/cDNA for SLCO1B7 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(40) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLCO1B7 Gene

Solute carrier organic anion transporter family, member 1B7 (non-functional):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLCO1B7 Gene

No ASD Table

Relevant External Links for SLCO1B7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLCO1B7 Gene

mRNA expression in normal human tissues for SLCO1B7 Gene

mRNA differential expression in normal tissues according to GTEx for SLCO1B7 Gene

This gene is overexpressed in Liver (x38.7) and Testis (x8.4).

Protein differential expression in normal tissues from HIPED for SLCO1B7 Gene

This gene is overexpressed in Liver (41.0) and Gallbladder (28.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SLCO1B7 Gene

SOURCE GeneReport for Unigene cluster for SLCO1B7 Gene Hs.729117

genes like me logo Genes that share expression patterns with SLCO1B7: view

Protein tissue co-expression partners for SLCO1B7 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SLCO1B7 Gene

Orthologs for SLCO1B7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLCO1B7 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SLCO1B7 35
  • 99.11 (n)
  • 98.59 (a)
-- 36
  • 91 (a)
(Bos Taurus)
Mammalia -- 36
  • 60 (a)
(Canis familiaris)
Mammalia OATPC 36
  • 62 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 45 (a)
(Mus musculus)
Mammalia Slco1b2 36
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 57 (a)
(Gallus gallus)
Aves -- 36
  • 35 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 33 (a)
Species with no ortholog for SLCO1B7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SLCO1B7 Gene

Gene Tree for SLCO1B7 (if available)
Gene Tree for SLCO1B7 (if available)

Paralogs for SLCO1B7 Gene

(13) SIMAP similar genes for SLCO1B7 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with SLCO1B7: view

Variants for SLCO1B7 Gene

Sequence variations from dbSNP and Humsavar for SLCO1B7 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1948793 -- 21,047,943(-) TTAAC(C/T)TTTAA intron-variant
rs1995409 -- 21,018,930(-) TCTGA(A/G)AAATC intron-variant
rs7133651 -- 21,017,123(+) TACTT(A/G)AGGAA intron-variant
rs7134137 -- 21,061,238(+) tgtta(C/T)tactt intron-variant
rs2088964 -- 21,088,857(+) acaaa(A/C)ctatg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLCO1B7 Gene

Variant ID Type Subtype PubMed ID
nsv898872 CNV Loss 21882294
nsv515735 CNV Gain+Loss 19592680
nsv898877 CNV Loss 21882294
nsv469159 CNV Loss 19166990
nsv898878 CNV Loss 21882294
nsv898879 CNV Loss 21882294

Variation tolerance for SLCO1B7 Gene

Residual Variation Intolerance Score: 97.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.25; 76.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLCO1B7 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLCO1B7 Gene

Disorders for SLCO1B7 Gene

Relevant External Links for SLCO1B7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SLCO1B7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLCO1B7 Gene

Publications for SLCO1B7 Gene

  1. Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition. (PMID: 20837016) Buch S. … Hampe J. (Gastroenterology 2010) 3 67

Products for SLCO1B7 Gene

Sources for SLCO1B7 Gene