Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SLCO1B7 Gene

Aliases for SLCO1B7 Gene

  • Solute Carrier Organic Anion Transporter Family, Member 1B7 (Non-Functional) 2 3
  • Liver-Specific Organic Anion Transporter 3 3 4
  • LST-3 3 4
  • LST3 3 4
  • Putative Solute Carrier Organic Anion Transporter Family Member 1B7 3
  • Liver-Specific Organic Anion Transporter 3TM12 3
  • Organic Anion Transporter LST-3b 3
  • LST-3TM12 3
  • SLC21A21 3
  • LST3TM12 4

External Ids for SLCO1B7 Gene

Summaries for SLCO1B7 Gene

GeneCards Summary for SLCO1B7 Gene

SLCO1B7 (Solute Carrier Organic Anion Transporter Family, Member 1B7 (Non-Functional)) is a Protein Coding gene. Among its related pathways are Bile secretion. GO annotations related to this gene include transporter activity. An important paralog of this gene is ENSG00000257046.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLCO1B7 Gene

Genomics for SLCO1B7 Gene

Genomic Location for SLCO1B7 Gene

Start:
21,015,696 bp from pter
End:
21,092,745 bp from pter
Size:
77,050 bases
Orientation:
Plus strand

Genomic View for SLCO1B7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLCO1B7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLCO1B7 Gene

No data available for Regulatory Elements for SLCO1B7 Gene

Proteins for SLCO1B7 Gene

  • Protein details for SLCO1B7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    G3V0H7-SO1B7_HUMAN
    Recommended name:
    Putative solute carrier organic anion transporter family member 1B7
    Protein Accession:
    G3V0H7
    Secondary Accessions:
    • Q71QF0

    Protein attributes for SLCO1B7 Gene

    Size:
    640 amino acids
    Molecular mass:
    71247 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLCO1B7 Gene

Proteomics data for SLCO1B7 Gene at MOPED

Post-translational modifications for SLCO1B7 Gene

No Post-translational modifications

Other Protein References for SLCO1B7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLCO1B7 Gene

Domains for SLCO1B7 Gene

Gene Families for SLCO1B7 Gene

HGNC:
  • SLC :Solute carriers

Protein Domains for SLCO1B7 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

SO1B7_HUMAN
Domain:
  • Contains 1 Kazal-like domain.:
    • G3V0H7
Family:
  • Belongs to the organo anion transporter (TC 2.A.60) family.:
    • G3V0H7
genes like me logo Genes that share domains with SLCO1B7: view

Function for SLCO1B7 Gene

Gene Ontology (GO) - Molecular Function for SLCO1B7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity IEA --
GO:0005515 protein binding --
GO:0022857 transmembrane transporter activity --
genes like me logo Genes that share ontologies with SLCO1B7: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLCO1B7 Gene

Localization for SLCO1B7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLCO1B7 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLCO1B7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLCO1B7: view

Pathways for SLCO1B7 Gene

SuperPathways for SLCO1B7 Gene

Superpath Contained pathways
1 Bile secretion
genes like me logo Genes that share pathways with SLCO1B7: view

Pathways by source for SLCO1B7 Gene

1 KEGG pathway for SLCO1B7 Gene

Interacting Proteins for SLCO1B7 Gene

Gene Ontology (GO) - Biological Process for SLCO1B7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:0055085 transmembrane transport --
genes like me logo Genes that share ontologies with SLCO1B7: view

Transcripts for SLCO1B7 Gene

mRNA/cDNA for SLCO1B7 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(40) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLCO1B7 Gene

Solute carrier organic anion transporter family, member 1B7 (non-functional):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLCO1B7 Gene

No ASD Table

Relevant External Links for SLCO1B7 Gene

GeneLoc Exon Structure for
SLCO1B7
ECgene alternative splicing isoforms for
SLCO1B7

Expression for SLCO1B7 Gene

mRNA expression in normal human tissues for SLCO1B7 Gene

mRNA differential expression in normal tissues according to GTEx for SLCO1B7 Gene

This gene is overexpressed in Liver (38.7) and Testis (8.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SLCO1B7 Gene

SOURCE GeneReport for Unigene cluster for SLCO1B7 Gene Hs.729117

genes like me logo Genes that share expressions with SLCO1B7: view

Orthologs for SLCO1B7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLCO1B7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 91 (a)
OneToMany
SLCO1B7 36
  • 99.11 (n)
  • 98.59 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 60 (a)
OneToMany
dog
(Canis familiaris)
Mammalia OATPC 37
  • 62 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Slco1b2 37
  • 56 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 45 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 57 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 37
  • 35 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 33 (a)
OneToMany
Species with no ortholog for SLCO1B7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SLCO1B7 Gene

ENSEMBL:
Gene Tree for SLCO1B7 (if available)
TreeFam:
Gene Tree for SLCO1B7 (if available)

Paralogs for SLCO1B7 Gene

Selected SIMAP similar genes for SLCO1B7 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with SLCO1B7: view

Variants for SLCO1B7 Gene

Sequence variations from dbSNP and Humsavar for SLCO1B7 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1472648 -- 21,025,669(-) ACACA(G/T)ACTGA intron-variant
rs1502495 -- 21,080,489(-) GGACA(C/T)GTTTC intron-variant
rs1502496 -- 21,055,567(+) AACAT(A/G)CTGAG intron-variant
rs1502497 -- 21,046,500(-) GCATG(G/T)TGGCA intron-variant
rs1502498 -- 21,077,063(-) TAAGG(C/T)ACACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLCO1B7 Gene

Variant ID Type Subtype PubMed ID
nsv898872 CNV Loss 21882294
nsv515735 CNV Gain+Loss 19592680
nsv898877 CNV Loss 21882294
nsv469159 CNV Loss 19166990
nsv898878 CNV Loss 21882294
nsv898879 CNV Loss 21882294

Relevant External Links for SLCO1B7 Gene

HapMap Linkage Disequilibrium report
SLCO1B7
Human Gene Mutation Database (HGMD)
SLCO1B7

Disorders for SLCO1B7 Gene

No disorders were found for SLCO1B7 Gene.

No data available for UniProtKB/Swiss-Prot for SLCO1B7 Gene

Publications for SLCO1B7 Gene

  1. Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition. (PMID: 20837016) Buch S. … Hampe J. (Gastroenterology 2010) 3
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4

Products for SLCO1B7 Gene

Sources for SLCO1B7 Gene

Back to Top

Content