SLCO1B7 Gene
protein-coding GIFtS: 32
GCID: GC12P020975
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solute carrier organic anion transporter family, member...
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Aliases
for SLCO1B7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
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| Solute Carrier Organic Anion Transporter Family, Member 1B7(Non-Functional)1 2 | | LST-3TM122 | | LST31 2 3 | | Liver-Specific Organic Anion Transporter 3TM122 | | SLC21A211 2 | | Organic Anion Transporter LST-3b2 | | Liver-Specific Organic Anion Transporter 32 3 | | Putative Solute Carrier Organic Anion Transporter Family Member 1B72 | | LST-32 3 | | LST3TM123 |
Export aliases for SLCO1B7 gene to outside databasesPrevious GC identifers: GC12P021169 GC12P020969 GC12P020970 |
Summaries
for SLCO1B7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for SLCO1B7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009714.17
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SLCO1B7
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLCO1B7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLCO1B7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p12.2 Ensembl cytogenetic band: 12p12.2 HGNC cytogenetic band: 12p12.3SLCO1B7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P020975: view genomic region
(about GC identifiers)
Start:
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20,968,673 bp from pter |
End:
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21,245,679 bp from pter |
Size:
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277,007 bases |
Orientation:
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plus strand |
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Proteins
for SLCO1B7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SO1B7_HUMAN, G3V0H7 (See
protein sequence)Recommended Name: Putative solute carrier organic anion transporter family member 1B7 Size: 640 amino acids; 71247 Da
Subcellular location: Cell membrane; Multi-pass membrane protein (Potential)
Caution: Product of a dubious CDS prediction. May encode a non-functional truncated protein
Secondary accessions: Q71QF0Explore the universe of human proteins at neXtProt for SLCO1B7: NX_G3V0H7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_G3V0H7
SLCO1B7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001009562.3
ENSEMBL proteins: ENSP00000394168 ENSP00000439857 ENSP00000452013
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SLCO1B7 for ontologies About GeneDecksing
SLCO1B7 Antibody Products:
Assay Products for SLCO1B7: |
Protein
Domains /
Families
for SLCO1B7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLCO1B7 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry G3V0H7ProtoNet protein and cluster: G3V0H7 UniProtKB/Swiss-Prot: SO1B7_HUMAN, G3V0H7Similarity: Belongs to the organo anion transporter (TC 2.A.60) familySimilarity: Contains 1 Kazal-like domain |
Function
for SLCO1B7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLCO1B7
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLCO1B7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for SLCO1B7 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLCO1B7 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SLCO1B7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLCO1B7 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005215 | transporter activity |
IEA | -- |
SLCO1B7 for ontologies About GeneDecksing
|
Pathways & Interactions
for SLCO1B7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLCO1B7
|
Drugs & Compounds
for SLCO1B7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SLCO1B7
Search CenterWatch for drugs/clinical trials and news about SLCO1B7 / SO1B7
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Transcripts
for SLCO1B7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLCO1B7 gene: NM_001009562.4 Unigene Cluster for SLCO1B7: Solute carrier organic anion transporter family, member 1B7 (non-functional) Hs.744627 [show with all ESTs]Unigene Representative Sequence: AF4016424 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000421593(uc010sin.2) ENST00000545916 ENST00000541784 ENST00000554957
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLCO1B7
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLCO1B7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for SLCO1B7 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLCO1B7 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SLCO1B7 |
Additional cDNA sequence: AF401642.1 1 DOTS entry: DT.102824387 24/40 AceView cDNA sequences (see all 40): BG562880 AA382692 BG618727 CB161473 CB161880 AB026257 CB161434 CB163667 BX283296 BX495197 BC005243 CB163230 CB147672 BC070172 BC020696 BM764855 BG569386 H62927 NM_006446 BG566359 AF401642 BG567055 AF060500 BG568493
GeneLoc Exon Structure
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Expression
for SLCO1B7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLCO1B7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAAGGATAC
About this image
See SLCO1B7 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.744627
SABiosciences Custom PCR Arrays for SLCO1B7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLCO1B7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SLCO1B7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLCO1B7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLCO1B7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLCO1B7 |
Orthologs
for SLCO1B7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for SLCO1B7 gene from 5/16 species (see all 16) About this table
ENSEMBL Gene Tree for SLCO1B7 (if available)
TreeFam Gene Tree for SLCO1B7 (if available) |
Paralogs
for SLCO1B7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLCO1B7 gene
- SLCO2A12 SLCO4C12 ENSG000002570622 SLCO3A12 SLCO1B32 SLCO5A12 SLCO2B12 SLCO6A12
- SLCO1B12 ENSG000002570462 SLCO4A12 SLCO1A22 SLCO1C12
13 SIMAP similar genes for SLCO1B7 using alignment to 3 protein entries: SO1B7_HUMAN (see all proteins):LST3 SLCO1B3 SLC21A8 SLCO1B1 SLCO1A2 SLCO1C1
SLCO3A1 DKFZp313M176 SLCO2B1 SLCO4C1 SLCO4A1 SLCO5A1
SLCO2A1
SLCO1B7 for paralogs About GeneDecksing
|
Genomic Variants
for SLCO1B7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for SLCO1B7 (20968673 - 21218673 bp, first 250kb of SLCO1B7)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SLCO1B7: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLCO1B7 |
|
Disorders
/ Diseases
for SLCO1B7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for SLCO1B7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLCO1B7 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SLCO1B7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition. (PubMed id 20837016)1 Buch S....Hampe J. (2010)
- The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for SLCO1B7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SLCO1B7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing SLCO1B7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLCO1B7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for SLCO1B7 gene:
Search GeneIP for patents involving SLCO1B7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLCO1B7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLCO1B7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLCO1B7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLCO1B7 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLCO1B7 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLCO1B7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLCO1B7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLCO1B7 |
|  |  |  | | | | Search ThermoFisher Antibodies for SLCO1B7 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SLCO1B7 |
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