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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC9B2 Gene

protein-coding   GIFtS: 49
GCID: GC04M103946

Solute Carrier Family 9, Subfamily B (NHA2, Cation Proton...

(Previous names: Na+/H+ exchanger domain containing 2, solute carrier family...)
(Previous symbol: NHEDC2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 9, Subfamily B (NHA2, Cation Proton Antiporter
2), Member 21 2
     Solute Carrier Family 9 Subfamily B Member 22 3
NHEDC21 2 3 5     Na(+)/H(+) Exchanger-Like Domain-Containing Protein 22 3
NHA22 3 5     NHE Domain-Containing Protein 22 3
Na+/H+ Exchanger Domain Containing 21 2     NHE102
Solute Carrier Family 9, Subfamily B (Cation Proton Antiporter 2), Member
21 2
     Mitochondrial Sodium/Hydrogen Exchanger 9B22
Mitochondrial Na(+)/H(+) Exchanger NHA22 3     Mitochondrial Sodium/Hydrogen Exchanger NHA22
Sodium/Hydrogen Exchanger-Like Domain-Containing Protein 22 3     

External Ids:    HGNC: 251431   Entrez Gene: 1333082   Ensembl: ENSG000001640387   OMIM: 6117895   UniProtKB: Q86UD53   

Export aliases for SLC9B2 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC9B2 Gene:
Sodium hydrogen antiporters, such as NHEDC2, convert the proton motive force established by the respiratory chain
or the F1F0 mitochondrial ATPase into sodium gradients that drive other energy-requiring processes, transduce
environmental signals into cell responses, or function in drug efflux (Xiang et al., 2007 (PubMed
18000046)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC9B2 Gene: 
SLC9B2 (solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2) is a protein-coding gene. Diseases associated with SLC9B2 include alcohol dependence, and essential hypertension, and among its related super-pathways are Stimuli-sensing channels and SLC-mediated transmembrane transport. GO annotations related to this gene include solute:hydrogen antiporter activity. An important paralog of this gene is SLC9B1P1.

UniProtKB/Swiss-Prot: SL9B2_HUMAN, Q86UD5
Function: Electroneutral exchange of protons for Na(+) and Li(+) across the inner mitochondrial membrane.
Contributes to the organellar volume homeostasis. Required for osteoclast differentiation and bone resorption
activity (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SLC9B2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC9B2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC9B2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC9B2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q24   Ensembl cytogenetic band:  4q24   HGNC cytogenetic band: 4q24

SLC9B2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC9B2 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M103946:  view genomic region     (about GC identifiers)

Start:
103,941,025 bp from pter      End:
104,006,986 bp from pter
Size:
65,962 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SL9B2_HUMAN, Q86UD5 (See protein sequence)
Recommended Name: Mitochondrial sodium/hydrogen exchanger 9B2  
Size: 537 amino acids; 57564 Da
Subcellular location: Mitochondrion membrane; Multi-pass membrane protein (By similarity)
Secondary accessions: B5ME52 Q6ZMD8 Q96D95
Alternative splicing: 2 isoforms:  Q86UD5-1   Q86UD5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC9B2: NX_Q86UD5

Explore proteomics data for SLC9B2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q86UD5

  • SLC9B2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC9B2 Protein Expression
    REFSEQ proteins: NP_849155.2  
    ENSEMBL proteins: 
     ENSP00000354574   ENSP00000421943   ENSP00000378265   ENSP00000425385   ENSP00000422477  
     ENSP00000426305   ENSP00000423496   ENSP00000345241  
    Reactome Protein details: Q86UD5
    Human Recombinant Protein Products for SLC9B2: 
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    Novus Biologicals SLC9B2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005743mitochondrial inner membrane TAS--
    GO:0016021integral to membrane IEA--

    SLC9B2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    1 InterPro protein domain:
     IPR006153 Cation/H_exchanger

    Graphical View of Domain Structure for InterPro Entry Q86UD5

    ProtoNet protein and cluster: Q86UD5

    1 Blocks protein domain: IPB006153 Sodium/hydrogen exchanger

    UniProtKB/Swiss-Prot: SL9B2_HUMAN, Q86UD5
    Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family


    SLC9B2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SL9B2_HUMAN, Q86UD5
    Function: Electroneutral exchange of protons for Na(+) and Li(+) across the inner mitochondrial membrane.
    Contributes to the organellar volume homeostasis. Required for osteoclast differentiation and bone resorption
    activity (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015299solute:hydrogen antiporter activity IEA--
    GO:0016491oxidoreductase activity ----
         
    SLC9B2 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Slc9b2):
     normal 

    SLC9B2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC9B2 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC9B2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ion channel transport
    Ion channel transport0.49
    Stimuli-sensing channels0.49
    2SLC-mediated transmembrane transport
    Transmembrane transport of small molecules0.50

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for SLC9B2
        Transmembrane transport of small molecules
    Stimuli-sensing channels
    Ion channel transport



    SLC9B2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC9B2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for SLC9B2 (Q86UD53 ENSP000003545744) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTU2Q2VPK53I2D: score=5 
    DENND6BQ8NEG73I2D: score=5 
    RTFDC1Q9BY423I2D: score=5 
    CACTINQ8WUQ73I2D: score=4 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0006814sodium ion transport IEA--
    GO:0034220ion transmembrane transport TAS--
    GO:0055085transmembrane transport TAS--

    SLC9B2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC9B2 (SL9B2)

    Search CenterWatch for drugs/clinical trials and news about SLC9B2 / SL9B2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC9B2 gene: 
    NM_178833.4  

    Unigene Cluster for SLC9B2:

    Solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
    Hs.546482  [show with all ESTs]
    Unigene Representative Sequence: BX640844
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000362026(uc010iln.2) ENST00000506288 ENST00000394785(uc003hwx.4 uc003hwy.3 uc011cew.2)
    ENST00000503103 ENST00000503230 ENST00000510976 ENST00000515424(uc011cey.2)
    ENST00000503818 ENST00000505838 ENST00000508136 ENST00000512806 ENST00000339611(uc011cex.1)

    miRNA
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    Additional mRNA sequence: 

    AK172823.1 AK297010.1 AK298506.1 AK299888.1 BC009732.1 BC047447.1 BX640844.1 

    15 DOTS entries:

    DT.407073  DT.100679223  DT.40285522  DT.100712987  DT.95368440  DT.100775719  DT.405763  DT.91646431 
    DT.100664442  DT.121253271  DT.97793914  DT.70102815  DT.92417724  DT.91720702  DT.92007695 

    24/115 AceView cDNA sequences (see all 115):

    F10816 BC009732 AA233152 BM702572 BM669493 BX454520 BX640844 BX359761 
    Z40158 BX381078 AA233228 BF724499 AI239938 BI962996 AI367621 BQ286748 
    BM971864 BM834042 BI914487 BF724498 BM683318 BX494716 BI560032 BX381077 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SLC9B2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15
    SP1:                                                  -                       -     -                       -         
    SP2:                                                  -                       -     -                                 
    SP3:                                                  -                       -     -           -     -     -         
    SP4:                                                                          -                                       
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for SLC9B2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC9B2 expression in normal human tissues (normalized intensities)      SLC9B2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGGAAAAAAA
    SLC9B2 Expression
    About this image


    SLC9B2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Stylopod Long Bone
     
     Cartilage (Muscoskeletal System)
             fetal cartilage   
     
     Liver (Hepatobiliary System)

    See SLC9B2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC9B2

    SOURCE GeneReport for Unigene cluster: Hs.546482

    UniProtKB/Swiss-Prot: SL9B2_HUMAN, Q86UD5
    Tissue specificity: Detected in red blood cells (at protein level)

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SLC9B2 gene from 5/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc9b25
    Nhedc21
    Na+/H+ exchanger domain containing 21, 5 81.9(n)1
    81.34(a)1
      3 (62.55 cM)5
    970861  NM_178877.61  NP_849208.41 
     1353077005 
    chicken
    (Gallus gallus)
    Aves NHEDC21 Na+/H+ exchanger domain containing 2 69.16(n)
    68.58(a)
      428776  XM_426332.3  XP_426332.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5710641 mitochondrial sodium/hydrogen exchanger NHA2-like 62.57(n)
    66.74(a)
      571064  XM_694618.2  XP_699710.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Nha11 Na[+]/H[+] hydrogen antiporter 1 46.91(n)
    37.07(a)
      33961  NM_164717.1  NP_723224.2 
    worm
    (Caenorhabditis elegans)
    Secernentea F41E7.16
    F57G8.56
    (see all 3)
    Protein F57G8.5
    (see all 3)
    22(a)
    22(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    X(10279599-10282845)
    V(16339024-16341534)


    ENSEMBL Gene Tree for SLC9B2 (if available)
    TreeFam Gene Tree for SLC9B2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC9B2 gene
    SLC9B1P12  SLC9B12  
    4 SIMAP similar genes for SLC9B2 using alignment to 5 protein entries:     SL9B2_HUMAN (see all proteins):
    BDH2    SLC9B1    SLC9B1P1    HSD17B14

    SLC9B2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/901 SNPs in SLC9B2 are shown (see all 901)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1473708101,2
    --103946230(+) TAGGAA/GTGTGA 1 -- int10--------
    rs1848985761,2
    --103946280(+) GATATC/GATCAA 1 -- int10--------
    rs1394714141,2
    --103946330(+) CATCAC/TTTCCT 1 -- int10--------
    rs1899098651,2
    --103946385(+) GGAGAC/TATGGT 1 -- int10--------
    rs1838395881,2
    --103946394(+) GTAGAC/GATCCA 1 -- int10--------
    rs729435121,2
    C--103946619(+) GAGTAT/ACCCTG 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1144946691,2
    F--103946635(+) ATTAAC/TGAACC 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1152314561,2
    C,F--103946872(+) GCCACT/AGAAAT 1 -- ut311Minor allele frequency- A:0.05WA 118
    rs1494463431,2
    --103946914(+) GATAAA/GGTTTT 1 -- ut310--------
    rs768428101,2
    F--103947024(+) AGTAAC/GGGAAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC9B2 (103941025 - 104006986 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SLC9B2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv4445CNV Insertion18451855
    nsv4446CNV Insertion18451855
    nsv830021CNV Loss17160897
    nsv461598CNV Loss19166990
    dgv1656e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611789    OMIM disorders: --

    4 diseases for SLC9B2:    About MalaCards
    alcohol dependence    essential hypertension    alcoholism    hypertension


    SLC9B2 for disorders           About GeneDecksing


    Export disorders for SLC9B2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC9B2 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with SLC9B2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Proteomic profile of osteoclast membrane proteins: identification of Na+/H+ exchanger domain containing 2 and its role in osteoclast fusion. (PubMed id 18600791)1, 3 Ha B.G....Park E.K. (2008)
    2. A human Na+/H+ antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension. (PubMed id 18000046)1, 2 Xiang M.... Rao R. (2007)
    3. Unconventional chemiosmotic coupling of NHA2, a mammal ian Na+/H+ antiporter, to a plasma membrane H+ gradient. (PubMed id 22948142)1 Kondapalli K.C....Rao R. (2012)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1 Kalsi G....Riley B.P. (2010)
    6. Mutational analysis of NHAoc/NHA2 in Saccharomyces ce revisiae. (PubMed id 20713131)1 Huang X....Battaglino R.A. (2010)
    7. Model-guided mutagenesis drives functional studies of human NHA2, implicated in hypertension. (PubMed id 20053353)1 Schushan M....Ben-Tal N. (2010)
    8. NHA-oc/NHA2: a mitochondrial cation-proton antiporter selectively expressed in osteoclasts. (PubMed id 17988971)1 Battaglino R.A....Stashenko P. (2008)
    9. Characterization of the sodium/hydrogen exchanger NHA2. (PubMed id 18508966)1 Fuster D.G....Moe O.W. (2008)
    10. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 133308 HGNC: 25143 AceView: LOC150159 Ensembl:ENSG00000164038 euGenes: HUgn133308
    ECgene: SLC9B2 H-InvDB: SLC9B2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC9B2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC9B2 gene:
    Search GeneIP for patents involving SLC9B2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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