Aliases for SLC9A7 Gene
External Ids for SLC9A7 Gene
Previous GeneCards Identifiers for SLC9A7 Gene
This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
GeneCards Summary for SLC9A7 Gene
SLC9A7 (Solute Carrier Family 9, Subfamily A (NHE7, Cation Proton Antiporter 7), Member 7) is a Protein Coding gene. Among its related pathways are CREB Pathway and TCR Signaling (Qiagen). GO annotations related to this gene include protein homodimerization activity and potassium:proton antiporter activity. An important paralog of this gene is SLC9A4.
UniProtKB/Swiss-Prot for SLC9A7 Gene
Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis.