SLC8A2 Gene
protein-coding GIFtS: 61
GCID: GC19M047931
|
|
solute carrier family 8 (sodium/calcium exchanger), member...
| |
Aliases
for SLC8A2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 8 (Sodium/Calcium Exchanger), Member 21 2 | | Sodium-Calcium Exchanger 22 | | NCX21 2 3 5 | | Sodium/Calcium Exchanger 22 | | KIAA10871 3 | | Solute Carrier Family 8 (Sodium-Calcium Exchanger), Member 22 | | Na(+)/Ca(2+)-Exchange Protein 22 3 | | Solute Carrier Family 8 Member 22 | | Na+/Ca2+-Exchanging Protein Nac22 | | |
Export aliases for SLC8A2 gene to outside databasesPrevious GC identifers: GC19M048578 GC19M048322 GC19M052607 GC19M052623 GC19M044359 |
Summaries
for SLC8A2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: NAC2_HUMAN, Q9UPR5Function: Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell duringrelaxation so as to prevent overloading of intracellular stores (By similarity)
 summary
for SLC8A2: The Na+/Ca2+ exchanger (NCX) is a low affinity, high capacitance calcium antiporter membrane protein that
functions to regulate intracellular calcium concentrations. It is located on the plasma, mitochondrial and
endoplasmic reticular membranes of excitable cells. Using the electrochemical gradient of Na+, one Ca2+ ion
is transported in exchange for three Na+ ions. The Na+/Ca2+ exchanger compliments the high affinity, low
capacitance Ca2+-ATPase and together, they are involved in a variety of cellular functions including control
of neurosecretion, relaxation of cardiac muscle, maintenance of intracellular Ca2+ stores in the endoplasmic
and sarcoplasmic reticuli and excitation-relaxation coupling. Under normal physiological conditions,
Na+/Ca2+ exchangers export Ca+ from the cell. However, under cellular stress, such as excitotoxicity, they
can switch to 'reverse mode', which has a protective effect.
|
Genomic Views
for SLC8A2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC8A2 gene promoter:
POU2F2 (Oct-2.1) Oct-B1 oct-B2 oct-B3 GATA-1 POU2F2 POU2F2C POU2F1 POU2F1a POU2F2B
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC8A2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC8A2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.3 Ensembl cytogenetic band: 19q13.32 HGNC cytogenetic band: 19q13.2SLC8A2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M047931: view genomic region
(about GC identifiers)
Start:
|
47,931,279 bp from pter |
End:
|
47,975,307 bp from pter |
Size:
|
44,029 bases |
Orientation:
|
minus strand |
|
Proteins
for SLC8A2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NAC2_HUMAN, Q9UPR5 (See
protein sequence)Recommended Name: Sodium/calcium exchanger 2 precursor Size: 921 amino acids; 100368 Da
Subcellular location: Membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAA83039.1; Type=Erroneous initiation;
Secondary accessions: B4DYQ9Explore the universe of human proteins at neXtProt for SLC8A2: NX_Q9UPR5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UPR5
SLC8A2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055878.1
ENSEMBL proteins: ENSP00000236877 ENSP00000437536 ENSP00000440588 Reactome Protein details: Q9UPR5
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
SLC8A2 for ontologies About GeneDecksing
SLC8A2 Antibody Products:
Assay Products for SLC8A2: |
Protein
Domains /
Families
for SLC8A2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC8A2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UPR5ProtoNet protein and cluster: Q9UPR5 3 Blocks protein families: IPB003644 Na-Ca exchanger/integrin-beta4 IPB004836 Na+/Ca2+ exchanger signature IPB004837 Sodium/calcium exchanger membrane region
UniProtKB/Swiss-Prot: NAC2_HUMAN, Q9UPR5Similarity: Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamilySimilarity: Contains 2 Calx-beta domains |
Function
for SLC8A2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NAC2_HUMAN, Q9UPR5Function: Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell duringrelaxation so as to prevent overloading of intracellular stores (By similarity)Enzyme regulation: By ATP (By similarity) Genatlas biochemistry entry for SLC8A2:solute carrier family 8 (sodium-calcium exchange),member 2,brain
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC8A2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC8A2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SLC8A2 (NM_015063) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC8A2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC8A2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC8A2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005432 | calcium:sodium antiporter activity |
IEA | -- | | GO:0005515 | protein binding |
-- | -- | | GO:0005516 | calmodulin binding |
IEA | -- |
SLC8A2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SLC8A2:
Animal Models:
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Slc8a2):
SLC8A2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SLC8A2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/12 super-pathways (see all 12) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Platelet calcium homeostasis | | | 2 | SLC-mediated transmembrane transport | | | 3 | Sodium-coupled transporters and pumps | | | 4 | Antiarrhythmic Pathway, Pharmacodynamics | | | 5 | Visual Cycle in Retinal Rods | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for SLC8A2
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SLC8A2
5/8 
Reactome Pathways for SLC8A2 (see all 8)
1  PharmGKB Pathway for SLC8A2
2 
Kegg Pathways (Kegg details for SLC8A2):
SLC8A2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC8A2
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/6 Interacting proteins for SLC8A2 (Q9UPR53 ENSP000002368774) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
SLC8A2 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC8A2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SLC8A2 for compounds About GeneDecksing
Compounds for SLC8A2 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| KB-R7943 mesylate | Na+/Ca2+ exchange inhibitor (reverse mode) | [182004-65-5] | | SN-6 | Selective Na+/Ca2+ exchange inhibitor (reverse mode) | [415697-08-4] | | CGP 37157 | Antagonist of mitochondrial Na+/Ca2+ exchange | [75450-34-9] |
2 HMDB Compounds for SLC8A2 About this table
2 Novoseek chemical compound relationships for SLC8A2 gene About this table
Search CenterWatch for drugs/clinical trials and news about SLC8A2 / NAC2
|
Transcripts
for SLC8A2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC8A2 gene: NM_015063.2 Unigene Cluster for SLC8A2: Solute carrier family 8 (sodium/calcium exchanger), member 2 Hs.172884 [show with all ESTs]Unigene Representative Sequence: NM_0150633 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000236877(uc010ele.3 uc002pgx.3 uc010xyq.2 uc010xyr.2)
ENST00000542837 ENST00000539381
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC8A2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC8A2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SLC8A2 (NM_015063) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC8A2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC8A2 |
Additional cDNA sequence: AB029010.1 AK293457.1 AK293836.1 AK293860.1 AK302552.1 AL512764.1 3 DOTS entries: DT.432581 DT.40310525 DT.121500847 24/32 AceView cDNA sequences (see all 32): BM127959 BM069629 AI457394 BI789259 BM676384 BU738783 CK819267 BM128286 AA398184 AL512764 AB029010 BG772726 AA365850 BX110856 BI962768 AI127885 BM069886 AI631453 AA028942 AA326195 BM713267 H50909 BI964750 R87591
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC8A2 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SLC8A2
|
Expression
for SLC8A2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC8A2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCCACAAAC
About this image
See SLC8A2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC8A2
SOURCE GeneReport for Unigene cluster: Hs.172884
SABiosciences Custom PCR Arrays for SLC8A2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC8A2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC8A2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC8A2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC8A2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC8A2 |
Orthologs
for SLC8A2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SLC8A2 gene from 7/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Slc8a21 , 5 |
solute carrier family 8 (sodium/calcium exchanger), member 2 less1, 5 |
88.2(n)1
94.46(a)1 |
|
7 (8.75 cM)5
1108911 NM_148946.21 NP_683748.11
161303005 |
lizard
(Anolis carolinensis) |
Reptilia |
SLC8A26 |
-- |
78(a) |
1 ↔ 1 |
AAWZ02036838(5315-7003) |
zebrafish
(Danio rerio) |
Actinopterygii |
slc8a2b1 |
solute carrier family 8 (sodium-calcium exchanger), member 2b less |
71.87(n)
72.9(a) |
|
567212 NM_001123284.1 NP_001116756.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Calx3 |
calcium:sodium antiporter |
48(a) |
|
93B3 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
Y113G7A.43 |
-- |
47(a) |
|
V(20097897-20112759) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
MHX16 |
magnesium/proton exchanger |
28(a) |
1 → many |
2(19524160-19527413) |
rice
(Oryza sativa) |
Liliopsida |
-- |
sodium/calcium exchanger protein, putative, expres... |
29(a) |
1 → many |
11(26016786-26020797) |
ENSEMBL Gene Tree for SLC8A2 (if available)
TreeFam Gene Tree for SLC8A2 (if available) |
Paralogs
for SLC8A2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLC8A2 gene
- SLC8A32 SLC24A32 SLC24A52 SLC8A12 SLC24A62 SLC24A42 SLC24A12 SLC24A22
4 SIMAP similar genes for SLC8A2 using alignment to 5 protein entries: NAC2_HUMAN (see all proteins):DKFZp761D171 SLC8A3 NACAIS4 SLC8A1
SLC8A2 for paralogs About GeneDecksing
|
Genomic Variants
for SLC8A2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC8A2 (47931279 - 47975307 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SLC8A2
1 CNV: 4083
1 Indel: 26304 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC8A2 |
|
Disorders
/ Diseases
for SLC8A2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SLC8A2 for disorders About GeneDecksing
OMIM gene information: 601901
OMIM disorders: --
9  diseases for SLC8A2: About MalaCardscerebral artery occlusion brain ischemia anoxia ischemia
alzheimer's disease cerebritis hypoxia neuronitis
retinitis
1 disease from the University of Copenhagen DISEASES database for SLC8A2:Brain ischemia 1 Novoseek disease relationship for SLC8A2 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ischemia |
20.3 |
1 |
15472108 (1) |
Human Genome Epidemiology (HuGE) Navigator: SLC8A2 (4 documents)
Export disorders for SLC8A2 gene to outside databases
|
Publications
for SLC8A2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC8A2 gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with SLC8A2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger. (PubMed id 8021246)1, 3, 9 Li Z....Philipson K.D. (1994)
- Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R....Ohara O. (1999)
- Inhibitory interaction of the plasma membrane Na+/Ca2+ exchangers with the 14-3-3 proteins. (PubMed id 16679322)1, 9 Pulina M.V....Carafoli E. (2006)
- High levels of synaptosomal Na(+)-Ca(2+) exchangers ( NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affec ted by Alzheimer's disease. (PubMed id 21382638)1 Sokolow S....Gylys K.H. (2011)
- Sodium-calcium exchange in intracellular calcium hand ling of human airway smooth muscle. (PubMed id 21858195)1 Sathish V....Prakash Y.S. (2011)
- Molecular genetic and epigenetic analysis of NCX2/SLC 8A2 at 19q13.3 in human gliomas. (PubMed id 20132488)1 Qu M....NistAcr M. (2010)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
- Calcineurin inhibits Na+/Ca2+ exchange in phenylephrine-treated hypertrophic cardiomyocytes. (PubMed id 15557343)1 Katanosaka Y....Shigekawa M. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
|
External Searches for SLC8A2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SLC8A2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC8A2 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SLC8A2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC8A2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SLC8A2 gene:
Search GeneIP for patents involving SLC8A2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLC8A2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC8A2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC8A2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC8A2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC8A2 | | OriGene 3'-UTR Clone for SLC8A2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC8A2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC8A2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SLC8A2 | | OriGene Custom Protein Services for SLC8A2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC8A2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC8A2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC8A2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC8A2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC8A2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC8A2 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | | SLC8A2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC8A2 |
|  |  |  | | | | Search ThermoFisher Antibodies for SLC8A2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC8A2 |
|
|
|
|
