Aliases for SLC8A2 Gene
External Ids for SLC8A2 Gene
Previous GeneCards Identifiers for SLC8A2 Gene
GeneCards Summary for SLC8A2 Gene
SLC8A2 (Solute Carrier Family 8 (Sodium/Calcium Exchanger), Member 2) is a Protein Coding gene. Among its related pathways are CREB Pathway and Platelet homeostasis. GO annotations related to this gene include calmodulin binding and calcium:sodium antiporter activity. An important paralog of this gene is ADGRV1.
UniProtKB/Swiss-Prot for SLC8A2 Gene
Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity).
The Na+/Ca2+ exchanger (NCX) is a low affinity, high capacitance calcium antiporter membrane protein that functions to regulate intracellular calcium concentrations. It is located on the plasma, mitochondrial and endoplasmic reticular membranes of excitable cells.