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Aliases for SLC7A6OS Gene

Aliases for SLC7A6OS Gene

  • Solute Carrier Family 7, Member 6 Opposite Strand 2 3
  • Solute Carrier Family 7 Member 6 Opposite Strand Transcript 4
  • ADAMS Proteinase-Related Protein 4

External Ids for SLC7A6OS Gene

Previous GeneCards Identifiers for SLC7A6OS Gene

  • GC16M066890
  • GC16M068332
  • GC16M054207
  • GC16M068320

Summaries for SLC7A6OS Gene

GeneCards Summary for SLC7A6OS Gene

SLC7A6OS (Solute Carrier Family 7, Member 6 Opposite Strand) is a Protein Coding gene.

UniProtKB/Swiss-Prot for SLC7A6OS Gene

  • Directs RNA polymerase II nuclear import.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC7A6OS Gene

Genomics for SLC7A6OS Gene

Regulatory Elements for SLC7A6OS Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC7A6OS Gene

68,284,503 bp from pter
68,310,965 bp from pter
26,463 bases
Minus strand

Genomic View for SLC7A6OS Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC7A6OS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC7A6OS Gene

Proteins for SLC7A6OS Gene

  • Protein details for SLC7A6OS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Probable RNA polymerase II nuclear localization protein SLC7A6OS
    Protein Accession:
    Secondary Accessions:
    • Q8TCZ3
    • Q9H8R8

    Protein attributes for SLC7A6OS Gene

    309 amino acids
    Molecular mass:
    35028 Da
    Quaternary structure:
    No Data Available
    • When transfected to S.cerevisiae cells, able to partially restore polymerase II mislocalization and cellular shape in IWR1 mutant cells.
    • Sequence=AAL79958.1; Type=Frameshift; Positions=234; Evidence={ECO:0000305};

neXtProt entry for SLC7A6OS Gene

Proteomics data for SLC7A6OS Gene at MOPED

Post-translational modifications for SLC7A6OS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC7A6OS Gene

Antibody Products

No data available for DME Specific Peptides for SLC7A6OS Gene

Domains for SLC7A6OS Gene

Protein Domains for SLC7A6OS Gene


Suggested Antigen Peptide Sequences for SLC7A6OS Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the IWR1/SLC7A6OS family.
  • Belongs to the IWR1/SLC7A6OS family.
genes like me logo Genes that share domains with SLC7A6OS: view

No data available for Gene Families for SLC7A6OS Gene

Function for SLC7A6OS Gene

Molecular function for SLC7A6OS Gene

UniProtKB/Swiss-Prot Function:
Directs RNA polymerase II nuclear import.

Phenotypes for SLC7A6OS Gene

GenomeRNAi human phenotypes for SLC7A6OS:
genes like me logo Genes that share phenotypes with SLC7A6OS: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC7A6OS Gene

Localization for SLC7A6OS Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC7A6OS Gene

Cytoplasm. Nucleus.

Subcellular locations from

Jensen Localization Image for SLC7A6OS Gene COMPARTMENTS Subcellular localization image for SLC7A6OS gene
Compartment Confidence
mitochondrion 3
nucleus 3
cytosol 1
extracellular 1

Gene Ontology (GO) - Cellular Components for SLC7A6OS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with SLC7A6OS: view

Pathways for SLC7A6OS Gene

SuperPathways for SLC7A6OS Gene

No Data Available

Interacting Proteins for SLC7A6OS Gene

Gene Ontology (GO) - Biological Process for SLC7A6OS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002244 hematopoietic progenitor cell differentiation IEA --
GO:0015031 protein transport IEA --
genes like me logo Genes that share ontologies with SLC7A6OS: view

No data available for Pathways by source for SLC7A6OS Gene

Transcripts for SLC7A6OS Gene

Unigene Clusters for SLC7A6OS Gene

Solute carrier family 7, member 6 opposite strand:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC7A6OS

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC7A6OS Gene

No ASD Table

Relevant External Links for SLC7A6OS Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC7A6OS Gene

mRNA expression in normal human tissues for SLC7A6OS Gene

Protein differential expression in normal tissues for SLC7A6OS Gene

This gene is overexpressed in Blymphocyte (25.7), Peripheral blood mononuclear cells (16.0), Retina (12.7), and Colon (6.8).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SLC7A6OS Gene

SOURCE GeneReport for Unigene cluster for SLC7A6OS Gene Hs.729520

genes like me logo Genes that share expressions with SLC7A6OS: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for SLC7A6OS Gene

Orthologs for SLC7A6OS Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC7A6OS Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SLC7A6OS 35
  • 80.72 (n)
  • 77.45 (a)
  • 77 (a)
(Canis familiaris)
Mammalia SLC7A6OS 35
  • 84.31 (n)
  • 81.17 (a)
  • 64 (a)
(Mus musculus)
Mammalia Slc7a6os 35
  • 79.93 (n)
  • 76.97 (a)
Slc7a6os 16
Slc7a6os 36
  • 76 (a)
(Pan troglodytes)
Mammalia SLC7A6OS 35
  • 99.46 (n)
  • 99.35 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Slc7a6os 35
  • 80.15 (n)
  • 77.63 (a)
(Monodelphis domestica)
Mammalia SLC7A6OS 36
  • 55 (a)
(Ornithorhynchus anatinus)
Mammalia SLC7A6OS 36
  • 32 (a)
(Gallus gallus)
Aves SLC7A6OS 35
  • 63.46 (n)
  • 55.67 (a)
  • 48 (a)
(Anolis carolinensis)
Reptilia SLC7A6OS 36
  • 46 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc7a6os 35
  • 55.26 (n)
  • 51.15 (a)
(Danio rerio)
Actinopterygii Dr.12894 35
slc7a6os 35
  • 58.56 (n)
  • 55.98 (a)
slc7a6os 36
  • 45 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2841 36
  • 24 (a)
Species with no ortholog for SLC7A6OS:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC7A6OS Gene

Gene Tree for SLC7A6OS (if available)
Gene Tree for SLC7A6OS (if available)

Paralogs for SLC7A6OS Gene

No data available for Paralogs for SLC7A6OS Gene

Variants for SLC7A6OS Gene

Sequence variations from dbSNP and Humsavar for SLC7A6OS Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3068658 -- 68,306,827(-) gaatg(-/AATG)aATAC intron-variant
rs4783615 -- 68,308,520(+) TACTC(A/G)CGAGG intron-variant
rs6499167 -- 68,303,895(+) AATAA(A/T)TTCTT intron-variant
rs7200884 -- 68,304,004(+) GCCCC(A/G)TCTGC intron-variant
rs8060690 -- 68,306,182(+) CCTTT(G/T)CTATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC7A6OS Gene

Variant ID Type Subtype PubMed ID
nsv510691 CNV Loss 20534489
nsv519368 CNV Loss 19592680

Relevant External Links for SLC7A6OS Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC7A6OS Gene

Disorders for SLC7A6OS Gene

No disorders were found for SLC7A6OS Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SLC7A6OS Gene

Publications for SLC7A6OS Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Molecular characterization and functional analysis of a protease-related protein in Chang-liver cells. (PMID: 20510023) Wang C. … Lin J. (BMB Rep 2010) 3
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for SLC7A6OS Gene

Sources for SLC7A6OS Gene

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