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Aliases for SLC7A6OS Gene

Aliases for SLC7A6OS Gene

  • Solute Carrier Family 7, Member 6 Opposite Strand 2 3
  • Solute Carrier Family 7 Member 6 Opposite Strand Transcript 4
  • ADAMS Proteinase-Related Protein 4

External Ids for SLC7A6OS Gene

Summaries for SLC7A6OS Gene

GeneCards Summary for SLC7A6OS Gene

SLC7A6OS (Solute Carrier Family 7, Member 6 Opposite Strand) is a Protein Coding gene.

UniProtKB/Swiss-Prot for SLC7A6OS Gene

  • Directs RNA polymerase II nuclear import.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC7A6OS Gene

Genomics for SLC7A6OS Gene

Genomic Location for SLC7A6OS Gene

Start:
68,284,503 bp from pter
End:
68,310,965 bp from pter
Size:
26,463 bases
Orientation:
Minus strand

Genomic View for SLC7A6OS Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC7A6OS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC7A6OS Gene

Regulatory Elements for SLC7A6OS Gene

Proteins for SLC7A6OS Gene

  • Protein details for SLC7A6OS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96CW6-S7A6O_HUMAN
    Recommended name:
    Probable RNA polymerase II nuclear localization protein SLC7A6OS
    Protein Accession:
    Q96CW6
    Secondary Accessions:
    • Q8TCZ3
    • Q9H8R8

    Protein attributes for SLC7A6OS Gene

    Size:
    309 amino acids
    Molecular mass:
    35028 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • When transfected to S.cerevisiae cells, able to partially restore polymerase II mislocalization and cellular shape in IWR1 mutant cells.
    SequenceCaution:
    • Sequence=AAL79958.1; Type=Frameshift; Positions=234; Evidence={ECO:0000305};

neXtProt entry for SLC7A6OS Gene

Proteomics data for SLC7A6OS Gene at MOPED

Post-translational modifications for SLC7A6OS Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC7A6OS Gene

No data available for DME Specific Peptides for SLC7A6OS Gene

Domains for SLC7A6OS Gene

Protein Domains for SLC7A6OS Gene

ProtoNet:

UniProtKB/Swiss-Prot:

S7A6O_HUMAN
Family:
  • Belongs to the IWR1/SLC7A6OS family.:
    • Q96CW6
genes like me logo Genes that share domains with SLC7A6OS: view

No data available for Gene Families for SLC7A6OS Gene

Function for SLC7A6OS Gene

Molecular function for SLC7A6OS Gene

UniProtKB/Swiss-Prot Function: Directs RNA polymerase II nuclear import.

Phenotypes for SLC7A6OS Gene

GenomeRNAi human phenotypes for SLC7A6OS:
genes like me logo Genes that share phenotypes with SLC7A6OS: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC7A6OS Gene

Localization for SLC7A6OS Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC7A6OS Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC7A6OS Gene COMPARTMENTS Subcellular localization image for SLC7A6OS gene
Compartment Confidence
mitochondrion 3
nucleus 3
cytosol 1
extracellular 1

Gene Ontology (GO) - Cellular Components for SLC7A6OS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with SLC7A6OS: view

Pathways for SLC7A6OS Gene

SuperPathways for SLC7A6OS Gene

No Data Available

Interacting Proteins for SLC7A6OS Gene

Gene Ontology (GO) - Biological Process for SLC7A6OS Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002244 hematopoietic progenitor cell differentiation IEA --
GO:0015031 protein transport IEA --
genes like me logo Genes that share ontologies with SLC7A6OS: view

No data available for Pathways by source for SLC7A6OS Gene

Transcripts for SLC7A6OS Gene

Unigene Clusters for SLC7A6OS Gene

Solute carrier family 7, member 6 opposite strand:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC7A6OS Gene

No ASD Table

Relevant External Links for SLC7A6OS Gene

GeneLoc Exon Structure for
SLC7A6OS
ECgene alternative splicing isoforms for
SLC7A6OS

Expression for SLC7A6OS Gene

mRNA expression in normal human tissues for SLC7A6OS Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SLC7A6OS Gene

SOURCE GeneReport for Unigene cluster for SLC7A6OS Gene Hs.729520

genes like me logo Genes that share expressions with SLC7A6OS: view

Orthologs for SLC7A6OS Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC7A6OS Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC7A6OS 36
  • 99.46 (n)
  • 99.35 (a)
SLC7A6OS 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC7A6OS 36
  • 80.72 (n)
  • 77.45 (a)
SLC7A6OS 37
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC7A6OS 36
  • 84.31 (n)
  • 81.17 (a)
SLC7A6OS 37
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc7a6os 36
  • 79.93 (n)
  • 76.97 (a)
Slc7a6os 16
Slc7a6os 37
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC7A6OS 37
  • 55 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SLC7A6OS 37
  • 32 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slc7a6os 36
  • 80.15 (n)
  • 77.63 (a)
chicken
(Gallus gallus)
Aves SLC7A6OS 36
  • 63.46 (n)
  • 55.67 (a)
SLC7A6OS 37
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC7A6OS 37
  • 46 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc7a6os 36
  • 55.26 (n)
  • 51.15 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.12894 36
slc7a6os 36
  • 58.56 (n)
  • 55.98 (a)
slc7a6os 37
  • 45 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2841 37
  • 24 (a)
OneToOne
Species with no ortholog for SLC7A6OS:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC7A6OS Gene

ENSEMBL:
Gene Tree for SLC7A6OS (if available)
TreeFam:
Gene Tree for SLC7A6OS (if available)

Paralogs for SLC7A6OS Gene

No data available for Paralogs for SLC7A6OS Gene

Variants for SLC7A6OS Gene

Sequence variations from dbSNP and Humsavar for SLC7A6OS Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3068658 -- 68,306,827(-) gaatg(-/AATG)aATAC intron-variant
rs4783615 -- 68,308,520(+) TACTC(A/G)CGAGG intron-variant
rs6499167 -- 68,303,895(+) AATAA(A/T)TTCTT intron-variant
rs7200884 -- 68,304,004(+) GCCCC(A/G)TCTGC intron-variant
rs8060690 -- 68,306,182(+) CCTTT(G/T)CTATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC7A6OS Gene

Variant ID Type Subtype PubMed ID
nsv510691 CNV Loss 20534489
nsv519368 CNV Loss 19592680

Relevant External Links for SLC7A6OS Gene

HapMap Linkage Disequilibrium report
SLC7A6OS
Human Gene Mutation Database (HGMD)
SLC7A6OS

Disorders for SLC7A6OS Gene

No disorders were found for SLC7A6OS Gene.

No data available for UniProtKB/Swiss-Prot for SLC7A6OS Gene

Publications for SLC7A6OS Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Molecular characterization and functional analysis of a protease-related protein in Chang-liver cells. (PMID: 20510023) Wang C. … Lin J. (BMB Rep 2010) 3
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for SLC7A6OS Gene

Sources for SLC7A6OS Gene

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