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Aliases for SLC7A5P2 Gene

Aliases for SLC7A5P2 Gene

  • Solute Carrier Family 7 (Amino Acid Transporter Light Chain, L System), Member 5 Pseudogene 2 2 3
  • IMAA 3 4
  • MMAA 3 4
  • Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 Pseudogene 2 3
  • HLAT1 3-Transmembrane Protein IMAA 4
  • HLAT1 3-Transmembrane Protein MMAA 4
  • LAT1-3TM Protein 2 3
  • SLC7A5 Pseudogene 3
  • HLAT1 3TM IMAA 4
  • HLAT1 3TM MMAA 4
  • HLAT1-3TM 3

External Ids for SLC7A5P2 Gene

Previous GeneCards Identifiers for SLC7A5P2 Gene

  • GC16M021529

Summaries for SLC7A5P2 Gene

GeneCards Summary for SLC7A5P2 Gene

SLC7A5P2 (Solute Carrier Family 7 (Amino Acid Transporter Light Chain, L System), Member 5 Pseudogene 2) is a Pseudogene. Diseases associated with SLC7A5P2 include histidinemia. Among its related pathways are Disease and Metabolism. GO annotations related to this gene include amino acid transmembrane transporter activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC7A5P2 Gene

Genomics for SLC7A5P2 Gene

Genomic Location for SLC7A5P2 Gene

Start:
21,517,893 bp from pter
End:
21,520,444 bp from pter
Size:
2,552 bases
Orientation:
Minus strand

Genomic View for SLC7A5P2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC7A5P2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC7A5P2 Gene

No data available for Regulatory Elements for SLC7A5P2 Gene

Proteins for SLC7A5P2 Gene

  • Protein details for SLC7A5P2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GIP4-LAT1L_HUMAN
    Recommended name:
    Putative L-type amino acid transporter 1-like protein IMAA
    Protein Accession:
    Q9GIP4
    Secondary Accessions:
    • Q6IPZ0
    • Q8MH62

    Protein attributes for SLC7A5P2 Gene

    Size:
    190 amino acids
    Molecular mass:
    19840 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC7A5P2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC7A5P2 Gene

Proteomics data for SLC7A5P2 Gene at MOPED

Post-translational modifications for SLC7A5P2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SLC7A5P2 Gene

Domains for SLC7A5P2 Gene

Gene Families for SLC7A5P2 Gene

HGNC:
  • SLC :Solute carriers

Protein Domains for SLC7A5P2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC7A5P2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9GIP4

UniProtKB/Swiss-Prot:

LAT1L_HUMAN :
  • Q9GIP4
Family:
  • Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
genes like me logo Genes that share domains with SLC7A5P2: view

Function for SLC7A5P2 Gene

Molecular function for SLC7A5P2 Gene

UniProtKB/Swiss-Prot Induction: Up-regulated by concanavalin-A stimulation.

Gene Ontology (GO) - Molecular Function for SLC7A5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015171 amino acid transmembrane transporter activity IEA --
genes like me logo Genes that share ontologies with SLC7A5P2: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC7A5P2 Gene

Localization for SLC7A5P2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC7A5P2 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC7A5P2 Gene COMPARTMENTS Subcellular localization image for SLC7A5P2 gene
Compartment Confidence
plasma membrane 3
peroxisome 1
vacuole 1

Gene Ontology (GO) - Cellular Components for SLC7A5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC7A5P2: view

Pathways for SLC7A5P2 Gene

SuperPathways for SLC7A5P2 Gene

Superpath Contained pathways
1 Defective BTD causes biotidinase deficiency
2 Fatty acid, triacylglycerol, and ketone body metabolism
3 Metabolism
4 Disease
genes like me logo Genes that share pathways with SLC7A5P2: view

Interacting Proteins for SLC7A5P2 Gene

Gene Ontology (GO) - Biological Process for SLC7A5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003333 amino acid transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC7A5P2: view

Transcripts for SLC7A5P2 Gene

mRNA/cDNA for SLC7A5P2 Gene

(29) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC7A5P2 Gene

Solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC7A5P2

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC7A5P2 Gene

No ASD Table

Relevant External Links for SLC7A5P2 Gene

GeneLoc Exon Structure for
SLC7A5P2
ECgene alternative splicing isoforms for
SLC7A5P2

Expression for SLC7A5P2 Gene

mRNA expression in normal human tissues for SLC7A5P2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SLC7A5P2 Gene

SOURCE GeneReport for Unigene cluster for SLC7A5P2 Gene Hs.664952

mRNA Expression by UniProt/SwissProt for SLC7A5P2 Gene

Q9GIP4-LAT1L_HUMAN
Tissue specificity: Expressed in peripheral blood mononuclear cells and lymphoid and myeloid cell lines.
genes like me logo Genes that share expressions with SLC7A5P2: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for SLC7A5P2 Gene

Orthologs for SLC7A5P2 Gene

Evolution for SLC7A5P2 Gene

ENSEMBL:
Gene Tree for SLC7A5P2 (if available)
TreeFam:
Gene Tree for SLC7A5P2 (if available)

No data available for Orthologs for SLC7A5P2 Gene

Paralogs for SLC7A5P2 Gene

Selected SIMAP similar genes for SLC7A5P2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC7A5P2: view

No data available for Paralogs for SLC7A5P2 Gene

Variants for SLC7A5P2 Gene

Sequence variations from dbSNP and Humsavar for SLC7A5P2 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs42138 -- 21,520,173(-) TCATG(A/G)GCTCG nc-transcript-variant
rs42139 -- 21,520,288(+) GCCAT(C/T)ATCTT nc-transcript-variant
rs42140 -- 21,520,360(+) GCACC(C/G)GCCAT nc-transcript-variant
rs481140 -- 21,518,092(+) CAGGC(C/T)GGTCT nc-transcript-variant
rs514970 -- 21,520,152(-) TGACG(C/T)CCACG nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC7A5P2 Gene

Variant ID Type Subtype PubMed ID
nsv905576 CNV Gain 21882294
esv34235 CNV Gain 17911159
dgv830e1 CNV Complex 17122850
nsv905578 CNV Gain 21882294
nsv433437 CNV Gain 18776910
nsv827584 CNV Gain 20364138
esv25717 CNV Gain+Loss 19812545
nsv433438 CNV Gain 18776910
esv33799 CNV Loss 17666407
nsv905579 CNV Gain 21882294
nsv9397 CNV Gain+Loss 18304495
nsv905580 CNV Loss 21882294
dgv2642n71 CNV Loss 21882294
nsv509606 CNV Insertion 20534489
essv17266 CNV CNV 17122850
dgv831e1 CNV Complex 17122850
dgv832e1 CNV Complex 17122850
nsv428322 CNV Gain 18775914
esv2421840 CNV Deletion 20811451
nsv442716 CNV CNV 18776908
esv2651779 CNV Gain 19546169
dgv2643n71 CNV Gain 21882294
dgv466n67 CNV Gain 20364138
nsv827589 CNV Loss 20364138

Relevant External Links for SLC7A5P2 Gene

HapMap Linkage Disequilibrium report
SLC7A5P2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC7A5P2 Gene

Disorders for SLC7A5P2 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for SLC7A5P2 Gene including...

Search for SLC7A5P2 Gene in MalaCards »

(1) University of Copenhagen DISEASES for SLC7A5P2 Gene

genes like me logo Genes that share disorders with SLC7A5P2: view

No data available for UniProtKB/Swiss-Prot for SLC7A5P2 Gene

Publications for SLC7A5P2 Gene

  1. Up-regulated expression of a novel gene in activated human peripheral blood mononuclear cells that is a truncated paralog of the human system L-amino acid transporter 1. (PMID: 12009310) Ito M. … Tsurudome M. (Int. J. Biochem. Cell Biol. 2002) 2 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4

Products for SLC7A5P2 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SLC7A5P2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SLC7A5P2
    • Block miRNA regulation of SLC7A5P2 using miScript Target Protectors

    Sources for SLC7A5P2 Gene

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