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SLC7A14 Gene

protein-coding   GIFtS: 51
GCID: GC03M170177

Solute Carrier Family 7, Member 14

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 7, Member 141 2     Solute Carrier Family 7 (Orphan Transporter), Member 142
KIAA16133 5     Solute Carrier Family 7 Member 143
Probable Cationic Amino Acid Transporter2     RP685
Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System),
Member 142
     

External Ids:    HGNC: 293261   Entrez Gene: 577092   Ensembl: ENSG000000132937   OMIM: 6157205   UniProtKB: Q8TBB63   

Export aliases for SLC7A14 gene to outside databases

Previous GC identifers: GC03M171666 GC03M167547


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SLC7A14 Gene:
SLC7A14 (solute carrier family 7, member 14) is a protein-coding gene. Diseases associated with SLC7A14 include cystinuria, and leber hereditary optic neuropathy. GO annotations related to this gene include amino acid transmembrane transporter activity. An important paralog of this gene is LOC284379.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC7A14 gene promoter:
         LHX3b/Lhx3b   Elk-1   p300   Pax-2   IRF-1   CUTL1   Pax-2a   LCR-F1   E2F   E2F-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC7A14 promoter sequence
   Search Chromatin IP Primers for SLC7A14

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC7A14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q26.2   Ensembl cytogenetic band:  3q26.2   HGNC cytogenetic band: 3q26.2

SLC7A14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC7A14 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M170177:  view genomic region     (about GC identifiers)

Start:
170,177,342 bp from pter      End:
170,303,863 bp from pter
Size:
126,522 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: S7A14_HUMAN, Q8TBB6 (See protein sequence)
Recommended Name: Probable cationic amino acid transporter  
Size: 771 amino acids; 84052 Da
Sequence caution: Sequence=BAB13439.1; Type=Erroneous termination; Positions=765; Note=Translated as Glu;
Secondary accessions: B3KV33 Q9HCF9

Explore the universe of human proteins at neXtProt for SLC7A14: NX_Q8TBB6

Explore proteomics data for SLC7A14 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn282, Asn676
  • Modification sites at PhosphoSitePlus

  • See SLC7A14 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_066000.2  
    ENSEMBL proteins: 
     ENSP00000231706  

    SLC7A14 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SLC7A14

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    Abcam antibodies for SLC7A14
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    LSBio Antibodies in human, mouse, rat for SLC7A14

    SLC7A14 Assay Products:

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    Cloud-Clone Corp. ELISAs for SLC7A14
    Cloud-Clone Corp. CLIAs for SLC7A14


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Probable cationic amino acid transporter
    SLC7 family

    1 InterPro protein domain:
     IPR002293 AA/rel_permease1

    Graphical View of Domain Structure for InterPro Entry Q8TBB6

    ProtoNet protein and cluster: Q8TBB6

    UniProtKB/Swiss-Prot: S7A14_HUMAN, Q8TBB6
    Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter
    (CAT) (TC 2.A.3.3) family


    SLC7A14 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015171amino acid transmembrane transporter activity IEA--
         
    SLC7A14 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC7A14
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    miRNA
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    Block miRNA regulation of human, mouse, rat SLC7A14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC7A14 (see all 117):
    hsa-miR-194* hsa-miR-323-3p hsa-miR-485-3p hsa-miR-128 hsa-miR-938 hsa-miR-374a hsa-miR-1273d hsa-miR-3161
    SwitchGear 3'UTR luciferase reporter plasmidSLC7A14 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SLC7A14
    Predesigned siRNA for gene silencing in human, mouse, rat SLC7A14

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SLC7A14

    Clone
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    OriGene ORF clones in mouse, rat for SLC7A14
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    GenScript: all cDNA clones in your preferred vector: SLC7A14 (NM_020949)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC7A14
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC7A14

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC7A14


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S7A14_HUMAN, Q8TBB6: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    SLC7A14 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC7A14
    Interactions:

        Search GeneGlobe Interaction Network for SLC7A14

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for SLC7A14 (ENSP000002317064) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1CAENSP000003260314STRING: ENSP00000326031
    OTCENSP000000390074STRING: ENSP00000039007
    SLC25A3ENSP000002283184STRING: ENSP00000228318
    CLN3ENSP000003530734STRING: ENSP00000353073
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0010923negative regulation of phosphatase activity IDA19389623
    GO:0055085transmembrane transport ----

    SLC7A14 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC7A14 (S7A14)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC7A14 gene (2 alternative transcripts): 
    NM_175917.2  NM_020949.2  

    Unigene Cluster for SLC7A14:

    Solute carrier family 7 (orphan transporter), member 14
    Hs.596660  [show with all ESTs]
    Unigene Representative Sequence: NM_020949
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000231706(uc003fgz.2) ENST00000466168
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SLC7A14 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC7A14 (see all 117):
    hsa-miR-194* hsa-miR-323-3p hsa-miR-485-3p hsa-miR-128 hsa-miR-938 hsa-miR-374a hsa-miR-1273d hsa-miR-3161
    SwitchGear 3'UTR luciferase reporter plasmidSLC7A14 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SLC7A14
    Predesigned siRNA for gene silencing in human, mouse, rat SLC7A14
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLC7A14 (NM_020949)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC7A14
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC7A14
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC7A14
      QuantiTect SYBR Green Assays in human, mouse, rat SLC7A14
      QuantiFast Probe-based Assays in human, mouse, rat SLC7A14

    Additional mRNA sequence: 

    AB046833.1 AK094547.1 AK122655.1 BC022968.1 

    2 DOTS entries:

    DT.86842740  DT.304460 

    Selected AceView cDNA sequences (see all 25):

    BQ184615 AW469542 BC022968 BG191336 BM680978 BX281331 AB046833 BX353179 
    BX331795 AK122655 CR599969 BX349909 BX369724 BI600900 BX353178 BG910182 
    AL707311 BX403114 BM725968 BQ186589 BF528139 AV753554 BG914052 BG202100 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC7A14 expression in normal human tissues (normalized intensities)      SLC7A14 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGAAAGAAA
    SLC7A14 Expression
    About this image


    SLC7A14 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Thalamus
     
     Pancreas (Endocrine System)    fully expand to see all 4 entries
             Endocrine Progenitor Cells Ventral Pancreatic Bud
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Telencephalon
     
     Paraxial Mesoderm (Gastrulation Derivatives)
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
     
     Neural Crest (Gastrulation Derivatives)
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
    SLC7A14 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC7A14 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.596660
        Custom PCR Arrays for SLC7A14
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC7A14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SLC7A14 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc7a141 , 5 solute carrier family 7 (cationic amino acid transporter, more1, 5 90.92(n)1
    96.76(a)1
      3 (15.17 cM)5
    2419191  NM_172861.31  NP_766449.11 
     312029105 
    chicken
    (Gallus gallus)
    Aves SLC7A141 solute carrier family 7 (orphan transporter), member more 80.69(n)
    90(a)
      424989  XM_422796.4  XP_422796.3 
    lizard
    (Anolis carolinensis)
    Reptilia SLC7A146
    solute carrier family 7, member 14
    90(a)
    1 ↔ 1
    3(7472227-7532505)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia slc7a141 solute carrier family 7 (orphan transporter), member more 75.09(n)
    84.37(a)
      100493085  XM_002931549.2  XP_002931595.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5662701 high affinity cationic amino acid transporter 1-like 72.66(n)
    77.84(a)
      566270  XM_005163407.1  XP_005163464.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG125311 CG12531 54.56(n)
    48.76(a)
      32986  NM_134506.3  NP_608350.2 
    worm
    (Caenorhabditis elegans)
    Secernentea C50D2.26
    F23F1.66
    (see all 3)
    Protein F23F1.6 (F23F1.6) mRNA, complete cds
    (see all 3)
    39(a)
    35(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    II(109165-111427) WBGene00016806
    II(35236-37313) WBGene00017747


    ENSEMBL Gene Tree for SLC7A14 (if available)
    TreeFam Gene Tree for SLC7A14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC7A14 gene
    LOC2843792  SLC7A22  SLC7A42  SLC7A12  SLC7A32  
    4 SIMAP similar genes for SLC7A14 using alignment to 1 protein entry:     S7A14_HUMAN:
    SLC7A1    SLC7A2    SLC7A3    SLC7A4

    SLC7A14 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC7A14 (see all 2549)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs102124141,2
    Cuntested1170199682(+) tcttaA/C/Gcattc 1 -- int10--------
    rs1464057411,2
    Cuntested1170218991(+) GGCTCC/TGGCCG 2 R G mis11Minor allele frequency- T:0.00NA 4550
    rs677715571,2
    C--167602804(+) AAAAA-/AT/T  
            
    ATATA
    1 -- int11NA 2
    rs349358631,2
    C--170129536(+) CTTCT-/T/T   
       T
    /TTT
    TTTTT
    2 -- int1 cds10--------
    rs1849747351,2
    --170176904(+) CATGTA/GATATG 1 -- ds50010--------
    rs1905739811,2
    --170176918(+) AATATA/GTGGCC 1 -- ds50010--------
    rs1141544541,2
    C,F--170176954(+) CAGGTA/GTCACC 1 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1818453091,2
    --170177121(+) GGTGTC/GGGGGG 1 -- ds50010--------
    rs615086971,2
    C,F--170177139(+) TTGAGT/GAGGAC 1 -- ds50012Minor allele frequency- G:0.06WA 120
    rs1477779551,2
    C--170177218(+) TGTTAA/GAAGAA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for SLC7A14 (170177342 - 170303863 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SLC7A14:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv7356OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC7A14
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC7A14

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615720   
    OMIM disorders: 615725  
    8 diseases for SLC7A14:    About MalaCards
    cystinuria    leber hereditary optic neuropathy    neuropathy    pneumonia
    tuberculosis    pancreatitis    cerebritis    malaria

    2 diseases from the University of Copenhagen DISEASES database for SLC7A14:
    Cystinuria     Leber hereditary optic neuropathy

    SLC7A14 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC7A14
    Human Genome Epidemiology (HuGE) Navigator: SLC7A14 (1 document)

    Export disorders for SLC7A14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC7A14 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SLC7A14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    4. A chimera carrying the functional domain of the orphan protein SLC7A14 in the backbone of SLC7A2 mediates trans-stimulated arginine transport. (PubMed id 22787143)1 Jaenecke I....Closs E.I. (J. Biol. Chem. 2012)
    5. Docking motif-guided mapping of the interactome of protein phosphatase-1. (PubMed id 19389623)1 Hendrickx A.... Bollen M. (Chem. Biol. 2009)
    6. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    7. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57709 HGNC: 29326 AceView: KIAA1613 Ensembl:ENSG00000013293 euGenes: HUgn57709
    ECgene: SLC7A14 H-InvDB: SLC7A14

    (According to HUGE)
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    HUGE: KIAA1613

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SLC7A14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC7A14 gene:
    Search GeneIP for patents involving SLC7A14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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