SLC6A8 Gene
protein-coding GIFtS: 61
GCID: GC0XP152953
|
|
solute carrier family 6 (neurotransmitter transporter, creatine),...
| |
Aliases
for SLC6A8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member81 2 | | Solute Carrier Family 6 Member 82 3 | | CT11 2 3 | | CRT2 | | CRTR1 2 5 | | Creatine Transporter SLC6A82 | | Creatine Transporter 12 3 | | Sodium- And Chloride-Dependent Creatine Transporter 12 |
Export aliases for SLC6A8 gene to outside databasesPrevious GC identifers: GC0XP147090 GC0XP149408 GC0XP150539 GC0XP151421 GC0XP152301 GC0XP152433 GC0XP152606 GC0XP141612 |
Summaries
for SLC6A8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SLC6A8:
The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out ofcells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encodingdifferent isoforms have been found for this gene. (provided by RefSeq, Dec 2008)
UniProtKB/Swiss-Prot: SC6A8_HUMAN, P48029Function: Required for the uptake of creatine in muscles and brain
Gene Wiki entry for SLC6A8
|
Genomic Views
for SLC6A8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167198.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC6A8 gene promoter:
E2F-3a Sp1 E2F E2F-1 E2F-2 Egr-4
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC6A8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC6A8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28SLC6A8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP152953: view genomic region
(about GC identifiers)
Start:
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152,953,554 bp from pter |
End:
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152,962,048 bp from pter |
Size:
|
8,495 bases |
Orientation:
|
plus strand |
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Proteins
for SLC6A8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SC6A8_HUMAN, P48029 (See
protein sequence)Recommended Name: Sodium- and chloride-dependent creatine transporter 1 Size: 635 amino acids; 70523 Da
Subcellular location: Membrane; Multi-pass membrane protein
Secondary accessions: B2KY47 B4DIA3 E9PFC0 Q13032 Q66I36Alternative splicing: 4 isoforms: P48029-1 P48029-2 P48029-3 P48029-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SLC6A8: NX_P48029
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P48029
SLC6A8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001136277.1 NP_001136278.1 NP_005620.1
ENSEMBL proteins: ENSP00000253122 ENSP00000403041 ENSP00000404046 ENSP00000400463 ENSP00000403682 ENSP00000394742 Reactome Protein details: P48029
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SLC6A8 for ontologies About GeneDecksing
SLC6A8 Antibody Products:
Assay Products for SLC6A8: |
Protein
Domains /
Families
for SLC6A8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC6A8 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P48029ProtoNet protein and cluster: P48029 1 Blocks protein family: IPB002984 Creatine transporter signature
UniProtKB/Swiss-Prot: SC6A8_HUMAN, P48029Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily |
Function
for SLC6A8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SC6A8_HUMAN, P48029Function: Required for the uptake of creatine in muscles and brain Genatlas biochemistry entry for SLC6A8:solute carrier family 6,member A8,neurotransmitter transporter,creatine
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC6A8 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC6A8 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC6A8 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- | | GO:0005308 | creatine transmembrane transporter activity |
NAS | 8661037 | | GO:0005309 | creatine:sodium symporter activity |
IEA | -- | | GO:0005328 | neurotransmitter:sodium symporter activity |
IEA | -- | | GO:0015220 | choline transmembrane transporter activity |
IEA | -- |
SLC6A8 for ontologies About GeneDecksing
Animal Models:
5 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Slc6a8):
SLC6A8 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SLC6A8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism of amino acids and derivatives | | | 2 | Metabolism | | | 3 | creatine-phosphate biosynthesis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for SLC6A8
SLC6A8 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC6A8
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for SLC6A8 (P480293 ENSP000002531224) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
SLC6A8 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC6A8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SLC6A8 for compounds About GeneDecksing
 Browse Tocris compounds for SLC6A8
2 HMDB Compounds for SLC6A8 About this table
1 DrugBank Compound for SLC6A8 About this table
3 Novoseek chemical compound relationships for SLC6A8 gene About this table
Search CenterWatch for drugs/clinical trials and news about SLC6A8 / SC6A8
|
Transcripts
for SLC6A8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC6A8 gene (3 alternative transcripts): NM_001142805.1 NM_001142806.1 NM_005629.3 Unigene Cluster for SLC6A8: Solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Hs.540696 [show with all ESTs]Unigene Representative Sequence: L3140910 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000253122(uc004fib.3 uc004fic.3 uc011myx.1 uc010nuj.2)
ENST00000476466 ENST00000430077(uc010nui.1) ENST00000466243 ENST00000467402
ENST00000429147 ENST00000485324 ENST00000413787 ENST00000442457 ENST00000457723
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC6A8 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC6A8 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): SLC6A8 (NM_001142805) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC6A8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC6A8 |
Additional cDNA sequence: AB209704.1 AK295495.1 AK309060.1 BC012355.1 BC081558.1 BC128089.1 L31409.1 U17986.1 11 DOTS entries: DT.208191 DT.121313457 DT.101960135 DT.95122312 DT.121313424 DT.121317745 DT.91770795 DT.95155614 DT.97777592 DT.121313459 DT.91747644 24/420 AceView cDNA sequences (see all 420): BU188850 F05064 CF243138 AI313496 BM686758 BM469011 AI188573 BQ941459 BI520007 AI554610 BU728309 CA424985 BM672940 BX283221 BM564619 BU753220 BQ427669 AI745370 BM771864 BU622792 AW297931 BM719623 AA435763 BM770194
GeneLoc Exon Structure
|
Expression
for SLC6A8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC6A8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCATTTTCCA
About this image
See SLC6A8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC6A8
SOURCE GeneReport for Unigene cluster: Hs.540696
UniProtKB/Swiss-Prot: SC6A8_HUMAN, P48029Tissue specificity: Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testisand prostate
SABiosciences Custom PCR Arrays for SLC6A8
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC6A8
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC6A8 |
Orthologs
for SLC6A8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SLC6A8 gene from 4/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SLC6A86 |
-- |
79(a) |
1 ↔ 1 |
Un(7934832-7935734) |
lizard
(Anolis carolinensis) |
Reptilia |
SLC6A86 |
-- |
85(a) |
1 ↔ 1 |
2(86877658-86918354) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.167702 |
Transcribed sequence with weak similarity to protein spP48029 (H.sapiens) S6A8_HUMAN Sodium- and chloride-dependent creatine transporter 1 (CT1) less |
75.91(n) |
|
BI472886.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
snf-113 |
Na(+)/Cl(-)-dependent GABA transporter |
47(a)
(best of 7) |
|
V(11307950-11311658) -- |
ENSEMBL Gene Tree for SLC6A8 (if available)
TreeFam Gene Tree for SLC6A8 (if available) |
Paralogs
for SLC6A8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SLC6A8 gene
- SLC6A62 SLC6A112 SLC6A122 SLC6A142 SLC6A52 SLC6A32 SLC6A12 SLC6A132
- SLC6A42 SLC6A72 SLC6A22 SLC6A92
18 SIMAP similar genes for SLC6A8 using alignment to 6 protein entries: SC6A8_HUMAN (see all proteins):SLC6A6 SLC6A12 SLC6A11 SLC6A1 SLC6A4 SLC6A13
SLC6A3 SLC6A9 SLC6A2 SLC6A7 SLC6A5 SLC6A14
SLC6A15 SLC6A20 DKFZp761I0921 SLC6A17 SLC6A19 SLC6A18
SLC6A8 for paralogs About GeneDecksing
5/9 Pseudogenes.org Pseudogenes for SLC6A8 (see all 9)
PGOHUM00000262930 PGOHUM00000262931 PGOHUM00000262939 PGOHUM00000262334 PGOHUM00000259130
|
Genomic Variants
for SLC6A8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC6A8 (152953554 - 152962048 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for SLC6A8
3 CNVs: 74083 97102 74082
Human Gene Mutation Database (HGMD): SLC6A8
Locus Specific Mutation Databases (LSDB): SLC6A8
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC6A8 |
|
Disorders
/ Diseases
for SLC6A8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SLC6A8 for disorders About GeneDecksing
OMIM gene information: 300036
OMIM disorders: 300352
UniProtKB/Swiss-Prot: SC6A8_HUMAN, P48029
Defects in SLC6A8 are the cause of X-linked creatine deficiency syndrome (XL-CDS) [MIM:300352]. XL-CDS causesdevelopmental delay, hypotonia, mental retardation, seizures, short stature and midface hypoplasia
13  diseases for SLC6A8: About MalaCardsx-linked creatine deficiency creatine deficiency syndrome fragile x syndrome autism spectrum disorder
intractable epilepsy x inactivation short stature intellectual disability
hypotonia seizures cerebritis prostatitis
sepsis
3 diseases from the University of Copenhagen DISEASES database for SLC6A8:AGAT deficiency Intellectual disability Ornithine translocase deficiency 2 Novoseek disease relationships for SLC6A8 gene About this table
GeneTests: SLC6A8
Creatine Deficiency Syndromes
Human Genome Epidemiology (HuGE) Navigator: SLC6A8 (3 documents)
Export disorders for SLC6A8 gene to outside databases
|
Publications
for SLC6A8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC6A8 gene, integrated from 9 sources (see all 53):
(articles sorted by number of sources associating them with SLC6A8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification, characterization and cloning of SLC6A8C, a novel splice variant of the creatine transporter gene. (PubMed id 18515020)1, 2, 9 Martinez-Munoz C....Salomons G.S. (2008)
- X-linked mental retardation with seizures and carrier manifestations is caused by a mutation in the creatine-transporter gene (SLC6A8) located in Xq28. (PubMed id 11898126)1, 2, 9 Hahn K.A.... Schwartz C.E. (2002)
- High frequency of creatine deficiency syndromes in patients with unexplained mental retardation. (PubMed id 17101918)1, 2 Lion-Francois L.... des Portes V. (2006)
- High prevalence of SLC6A8 deficiency in X-linked mental retardation. (PubMed id 15154114)1, 2 Rosenberg E.H.... Salomons G.S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- X-linked creatine deficiency syndrome: a novel mutation in creatine transporter gene SLC6A8. (PubMed id 12210795)1, 2 Bizzi A.... Uziel G. (2002)
- The genomic organization of a human creatine transporter (CRTR) gene located in Xq28. (PubMed id 8661155)1, 2 Sandoval N....Platzer M. (1996)
- Assignment of the creatine transporter gene (SLC6A8) to human chromosome Xq28 telomeric to G6PD. (PubMed id 7774949)1, 3 Gregor P....Warren S.T. (1995)
- Cloning and sequencing of a cDNA encoding a novel member of the human brain GABA/noradrenaline neurotransmitter transporter family. (PubMed id 7622069)1, 2 Barnwell L.F.... Townsel J.G. (1995)
- Cloning, pharmacological characterization, and genomic localization of the human creatine transporter. (PubMed id 7953292)1, 2 Nash S.R.... Caron M.G. (1994)
|
External Searches for SLC6A8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SLC6A8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC6A8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC6A8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC6A8 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SLC6A8 |
|
| | |
About This Section
| Patent Information for SLC6A8 gene:
Search GeneIP for patents involving SLC6A8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLC6A8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC6A8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC6A8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC6A8 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC6A8 | | OriGene 3'-UTR Clone for SLC6A8 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC6A8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC6A8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SLC6A8 | | OriGene Custom Protein Services for SLC6A8 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC6A8 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC6A8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC6A8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC6A8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC6A8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC6A8 |
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| | | | Search Tocris compounds for SLC6A8 |
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 | | | SLC6A8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC6A8 |
|  |  |  | | | | Search ThermoFisher Antibodies for SLC6A8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC6A8 |
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