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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC6A20 Gene

protein-coding   GIFtS: 52
GCID: GC03M045796

solute carrier family 6 (proline IMINO transporter), member...
 Explore 6 diseases affiliated with
SLC6A20 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC6A20    

Aliases
for SLC6A20 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 6 (Proline IMINO Transporter), Member 201 2     Orphan Transporter XT32
XT31 2 3 5     Sodium- And Chloride-Dependent Transporter XTRP32
Xtrp31 2     Solute Carrier Family 6 (Neurotransmitter Transporter), Member 202
Sodium/Imino-Acid Transporter 12 3     X Transporter Protein 32
Transporter RB21A Homolog2 3     XTRP33
SIT12 3     Solute Carrier Family 6 Member 203
Neurotransmitter Transporter RB21A2     

External Ids:    HGNC: 309271   Entrez Gene: 547162   Ensembl: ENSG000001638177   OMIM: 6056165   UniProtKB: Q9NP913   

Export aliases for SLC6A20 gene to outside databases

Previous GC identifers: GC03M045758 GC03M045771


Summaries
for SLC6A20 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC6A20:
Transport of small hydrophilic substances across cell membranes is mediated by substrate-specific transporter proteins
which have been classified into several families of related genes. The protein encoded by this gene is a member of the
subgroup of transporter with unidentified substrates within the Na+ and Cl- coupled transporter family. This gene is
expressed in kidney, and its alternative splicing generates 2 transcript variants. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: S6A20_HUMAN, Q9NP91
Function: Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as
well as N-methylated amino acids. Involved in the transport of glycine

Gene Wiki entry for SLC6A20


Genomic Views
for SLC6A20 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC6A20 gene promoter:
         ATF-2   FOXO3   FOXO3b   PPAR-gamma1   E2F-1   E2F   FOXO4   FOXO3a   PPAR-gamma2   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC6A20 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC6A20

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC6A20


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.6

SLC6A20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC6A20 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M045796:  view genomic region     (about GC identifiers)

Start:
 45,796,941 bp from pter      End:
 45,838,035 bp from pter
Size:
 41,095 bases      Orientation:
 minus strand

Proteins
for SLC6A20 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: S6A20_HUMAN, Q9NP91 (See protein sequence)
Recommended Name: Sodium- and chloride-dependent transporter XTRP3  
Size: 592 amino acids; 65914 Da
Subcellular location: Apical cell membrane; Multi-pass membrane protein (By similarity). Note=Located in the apical
brush border membrane of kidney proximal tubule cells (By similarity)
Sequence caution: Sequence=AAL75944.1; Type=Erroneous initiation;
Secondary accessions: A1A4F2 O75590 Q8TF10 Q9NPQ2 Q9NQ77
Alternative splicing: 2 isoforms:  Q9NP91-1   Q9NP91-2   

Explore the universe of human proteins at neXtProt for SLC6A20: NX_Q9NP91

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NP91

    • SLC6A20 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_064593.1  NP_071800.1  

    ENSEMBL proteins: 
     ENSP00000296133   ENSP00000346298   ENSP00000395506   ENSP00000404310  
    Reactome Protein details: Q9NP91
    Human Recombinant Protein Products: 
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    Uscn Proteins for SLC6A20

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane IEA--
    GO:0016324apical plasma membrane ISS--


    SLC6A20 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SLC6A20 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC6A20 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR000175 Na/ntran_symport
     IPR002438 Na/ntran_symport_orphan

    Graphical View of Domain Structure for InterPro Entry Q9NP91

    ProtoNet protein and cluster: Q9NP91

    1 Blocks protein family: IPB002438 Orphan neurotransmitter transporter signature

    UniProtKB/Swiss-Prot: S6A20_HUMAN, Q9NP91
    Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A20 subfamily


    Function
    for SLC6A20 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: S6A20_HUMAN, Q9NP91
    Function: Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as
    well as N-methylated amino acids. Involved in the transport of glycine

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    SwitchGear 3'UTR luciferase reporter plasmid: SLC6A20 3' UTR sequence
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    Gene Editing
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    Clone
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005328neurotransmitter:sodium symporter activity IEA--
    GO:0015171amino acid transmembrane transporter activity IDA15632147


    SLC6A20 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SLC6A20:
     Decreased viability of wild-ty 


    Pathways & Interactions
    for SLC6A20 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Amino acid and oligopeptide SLC transporters
    		Amino acid and oligopeptide SLC transporters1.00
    		Transport of inorganic cations/anions and amino acids/oligopeptides0.52
    		Amino acid transport across the plasma membrane0.63
    2SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    		Transmembrane transport of small molecules0.50
    3Amine compound SLC transporters
    		Amine compound SLC transporters1.00
    		Na+/Cl- dependent neurotransmitter transporters0.63

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/8        Reactome Pathways for SLC6A20 (see all 8)
        Na+/Cl- dependent neurotransmitter transporters
    Amino acid transport across the plasma membrane
    Amine compound SLC transporters
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules



    SLC6A20 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC6A20

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003333amino acid transmembrane transport IDA15632147
    GO:0006811ion transport TAS--
    GO:0006865amino acid transport TAS--
    GO:0015816glycine transport IMP19033659
    GO:0015824proline transport IMP19033659


    SLC6A20 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC6A20 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC6A20

    2 HMDB Compounds for SLC6A20    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    SodiumSodium (see all 2)7440-23-5--
    Search CenterWatch for drugs/clinical trials and news about SLC6A20 / S6A20 

    Transcripts
    for SLC6A20 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC6A20 gene (2 alternative transcripts): 
    NM_020208.3  NM_022405.3  

    Unigene Cluster for SLC6A20:

    Solute carrier family 6 (proline IMINO transporter), member 20
    Hs.413095  [show with all ESTs]
    Unigene Representative Sequence: NM_020208
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000353278(uc003cow.3) ENST00000358525(uc011bai.2 uc011baj.2)
    ENST00000473146 ENST00000493980 ENST00000413781 ENST00000470226 ENST00000456124


    miRNA
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    hsa-miR-183* hsa-miR-610 hsa-miR-571 hsa-let-7g* hsa-miR-3674 hsa-let-7a-2*
    SwitchGear 3'UTR luciferase reporter plasmid: SLC6A20 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AF075260.1 AJ276207.1 AJ276208.1 AL389979.1 BC036073.1 BC126197.1 BC136431.1 BC144087.1 

    5 DOTS entries:

    DT.101979329  DT.95165442  DT.40201073  DT.100748350  DT.95260371 

    24/53 AceView cDNA sequences (see all 53):

    AI364647 NM_020208 AL389979 CB241149 AI733761 CB853385 AW137313 AF125107 
    CD643407 AI569553 NM_022405 AI269820 CA394539 BM707737 BC036073 AI732605 
    BM709453 AW962443 AF075260 AA296916 AI761527 AA316835 AI732447 BU733412 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SLC6A20    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b
    SP1:              -     -                             -                                             
    SP2:                                                                                                
    SP3:                                                                                                


    ECgene alternative splicing isoforms for SLC6A20

    Expression
    for SLC6A20 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC6A20 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC6A20 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyProximal TubuleProximal Tubule CellsKidney
    BrainBlood Brain BarrierAdult Endothelial CellsBlood Brain Barrier, Endothelium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)

    See SLC6A20 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC6A20

    SOURCE GeneReport for Unigene cluster: Hs.413095

    UniProtKB/Swiss-Prot: S6A20_HUMAN, Q9NP91
    Tissue specificity: Kidney and small intestine. Expressed in the S3 segment of the proximal tubule

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    In Situ
    Assay Products:     
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    Orthologs
    for SLC6A20 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for SLC6A20 gene from 4/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SLC6A201 solute carrier family 6 (proline IMINO transporter), more 78.66(n)
    83.28(a)    		   420699  XM_418798.2  XP_418798.2 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC6A206
    		 --
    		 79(a)
    		 1 ↔ 1
    		 GL343324.1(220789-246340)
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG430666
    		 --
    		 36(a)
    		 1 → many
    		 2R(14402081-14413944)
    worm
    (Caenorhabditis elegans)    		 Secernentea snf-66
    snf-126
    		 Sodium-dependent acetylcholine transporter
    Sodium:Neurotransmitter symporter Family family me...
    		 19(a)
    14(a)
    		 possible ortholog
    possible ortholog
    		 III(1520216-1532760)
    X(9029423-9033904)


    ENSEMBL Gene Tree for SLC6A20 (if available)
    TreeFam Gene Tree for SLC6A20 (if available) 

    Paralogs
    for SLC6A20 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC6A20 gene
    SLC6A152  SLC6A172  SLC6A182  SLC6A162  SLC6A192  
    18/21 SIMAP similar genes for SLC6A20 using alignment to 3 protein entries:     S6A20_HUMAN (see all proteins) (see all similar genes):
    DAT1    SLC6A15    SLC6A19    DKFZp761I0921    SLC6A17    SLC6A18
    5HTT    SLC6A4    SLC6A6    SLC6A16    SLC6A3    SLC6A8
    SLC6A1    SLC6A7    SLC6A11    SLC6A12    SLC6A13    SLC6A5

    SLC6A20 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SLC6A20
    PGOHUM00000259827


    Genomic Variants
    for SLC6A20 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/735 NCBI SNPs in SLC6A20 are shown (see all 735)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs172794371,2
    		C,F,H,pathogenic86677225(+) ACGCCG/ATGAAA 3 /T /M mis1 int1 ese319Minor allele frequency- A:0.06NA NS EA EU 2957
    rs1887752441,2
    		--45796492(+) CACTCA/CCCCCT 2 -- ds50010--------
    rs1443045731,2
    		--45796565(+) AGAGAC/TGCTGA 2 -- ds50010--------
    rs1808029191,2
    		--45796623(+) TGCAGC/TAATTC 2 -- ds50010--------
    rs22510211,2
    		C,F,O,H,--45796657(-) TTGGCC/TGGATT 2 -- ds500141Minor allele frequency- T:0.29EA NS NA CSA WA 5298
    rs1510275681,2
    		--45796746(+) TGGTGC/TGGTCT 2 -- ds50010--------
    rs744106751,2
    		C--45796765(+) ATATGA/CAGAGG 2 -- ds50010--------
    rs1854706771,2
    		--45796802(+) AAAGGA/TTGGAT 2 -- ds50010--------
    rs1409240121,2
    		--45796878(+) ATCTTA/GTGTTG 2 -- ds50010--------
    rs1502020411,2
    		--45796949(+) AGATAA/CACTTG 2 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC6A20 (45796941 - 45838035 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC6A20: --
    Human Gene Mutation Database (HGMD): SLC6A20

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    Disorders / Diseases
    for SLC6A20 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC6A20 for disorders           About GeneDecksing

    OMIM gene information: 605616   
    OMIM disorders: 138500  242600  
    UniProtKB/Swiss-Prot: S6A20_HUMAN, Q9NP91
  • Defects in SLC6A20 are a cause of hyperglycinuria (HG) [MIM:138500]. It is a condition characterized by excess
    • of glycine in the urine. In some cases it is associated with renal colic and renal oxalate stones
  • Defects in SLC6A20 are a cause of iminoglycinuria (IG) [MIM:242600]. It is a disorder of renal tubular
    • reabsorption of glycine and imino acids (proline and hydroxyproline), marked by excessive levels of all three
    substances in the urine. Note=Haploinsufficiency of SLC6A20 combined with deficiency of the neutral amino acid
    transporter SLC6A19 or partially inactivating mutations in SLC36A2, is responsible for iminoglycinuria. Additional
    polymorphisms and mutations in SLC6A18 can contribute to the IG phenotype in some families

    6 diseases for SLC6A20:    About MalaCards
    iminoglycinuria, digenic    iminoglycinuria    hyperglycinuria    aminoaciduria
    malignant mesothelioma    pneumonia

    2 diseases from the University of Copenhagen DISEASES database for SLC6A20:
    Hartnup disease     Pellagra

    Export disorders for SLC6A20 gene to outside databases

    Publications
    for SLC6A20 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC6A20 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with SLC6A20)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The LZTFL1 gene is a part of a transcriptional map covering 250 kb within the common eliminated region 1 (C3CER1) in 3p21.3. (PubMed id 11352561)1, 2, 3 Kiss H....Dumanski J.P. (2001)
    2. Cloning, gene structure, and genomic localization of an orphan transporter from mouse kidney with six alternatively-spliced isoforms. (PubMed id 9932288)1, 2, 3 Nash S.R.... Caron M.G. (1998)
    3. Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino. (PubMed id 15632147)1, 2, 9 Takanaga H.... Hediger M.A. (2005)
    4. Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters. (PubMed id 19033659)1, 2 Broer S....Rasko J.E. (2008)
    5. Sodium translocation by the iminoglycinuria associate d imino transporter (SLC6A20). (PubMed id 19657969)1, 9 BrAPer A....BrAPer S. (2009)
    6. Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)1 Kennedy R.B....Poland G.A. (2012)
    7. A genome-wide association study of metabolic traits i n human urine. (PubMed id 21572414)1 Suhre K....Nauck M. (2011)
    8. Amino acid transport across mammalian intestinal and renal epithelia. (PubMed id 18195088)1 BrAPer S. (2008)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. Differential sensitivity of v-Myb and c-Myb to Wnt-1-induced protein degradation. (PubMed id 15308626)1 Kanei-Ishii C....Ishii S. (2004)

    External Searches for SLC6A20 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
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    Genome Databases showing SLC6A20 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54716 HGNC: 30927 AceView: SLC6A20 Ensembl:ENSG00000163817 euGenes: HUgn54716
    ECgene: SLC6A20 H-InvDB: SLC6A20

    Other Databases showing SLC6A20 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC6A20 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC6A20 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC6A20 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC6A20 gene:
    Search GeneIP for patents involving SLC6A20

    GeneCards and IP:
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