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SLC6A18 Gene

protein-coding   GIFtS: 54
GCID: GC05P001281

Solute Carrier Family 6 (Neutral Amino Acid Transporter),...

(Previous names: solute carrier family 6 (neurotransmitter transporter),...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 6 (Neutral Amino Acid Transporter), Member 181 2     XTRP23 5
Solute Carrier Family 6 (Neurotransmitter Transporter), Member 181 2     Xtrp22
Solute Carrier Family 6, Member 181 2     Sodium Channel-Like Protein2
Sodium- And Chloride-Dependent Transporter XTRP22 3     Sodium-Dependent Neutral Amino Acid Transporter B(0)AT32
System B(0) Neutral Amino Acid Transporter AT32 3     Solute Carrier Family 6 Member 183

External Ids:    HGNC: 264411   Entrez Gene: 3489322   Ensembl: ENSG000001643637   OMIM: 6103005   UniProtKB: Q96N873   

Export aliases for SLC6A18 gene to outside databases

Previous GC identifer: GC05P001279


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC6A18 Gene:
The SLC6 family of proteins, which includes SLC6A18, act as specific transporters for neurotransmitters, amino
acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the
energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 (PubMed
16125675)).(supplied by OMIM, Apr 2010)

GeneCards Summary for SLC6A18 Gene:
SLC6A18 (solute carrier family 6 (neutral amino acid transporter), member 18) is a protein-coding gene. Diseases associated with SLC6A18 include iminoglycinuria, and hyperglycinuria. GO annotations related to this gene include neurotransmitter:sodium symporter activity. An important paralog of this gene is SLC6A15.

UniProtKB/Swiss-Prot: S6A18_HUMAN, Q96N87
Function: Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity)

Gene Wiki entry for SLC6A18 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NT_006576.17  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC6A18 gene promoter:
         Egr-3   p53   RelA   NF-kappaB   HNF-4alpha1   HEN1   Max   FOXO4   NF-kappaB1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC6A18 promoter sequence
   Search Chromatin IP Primers for SLC6A18

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC6A18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p15.33   Ensembl cytogenetic band:  5p15.33   HGNC cytogenetic band: 5p15

SLC6A18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC6A18 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P001281:  view genomic region     (about GC identifiers)

Start:
1,225,470 bp from pter      End:
1,246,304 bp from pter
Size:
20,835 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: S6A18_HUMAN, Q96N87 (See protein sequence)
Recommended Name: Sodium-dependent neutral amino acid transporter B(0)AT3  
Size: 628 amino acids; 70897 Da
Subunit: Associates with TMEM27 (By similarity). TMEM27 association is required for functional expression in
kidney (By similarity)

Explore the universe of human proteins at neXtProt for SLC6A18: NX_Q96N87

Explore proteomics data for SLC6A18 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn144, Asn168, Asn174, Asn354
  • Modification sites at PhosphoSitePlus

  • See SLC6A18 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_872438.2  
    ENSEMBL proteins: 
     ENSP00000323549   ENSP00000296821  
    Reactome Protein details: Q96N87

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    Browse Proteins at Cloud-Clone Corp.

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: B0AT3
    Neutral amino acid transporter subfamily

    2 InterPro protein domains:
     IPR000175 Na/ntran_symport
     IPR002438 Na/ntran_symport_orphan

    Graphical View of Domain Structure for InterPro Entry Q96N87

    ProtoNet protein and cluster: Q96N87

    1 Blocks protein domain: IPB002438 Orphan neurotransmitter transporter signature

    UniProtKB/Swiss-Prot: S6A18_HUMAN, Q96N87
    Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A18 subfamily


    SLC6A18 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S6A18_HUMAN, Q96N87
    Function: Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005328neurotransmitter:sodium symporter activity IEA--
         
    SLC6A18 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Slc6a18):
     cardiovascular system  homeostasis/metabolism  renal/urinary system 

    SLC6A18 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for SLC6A18: Slc6a18tm1Lex Slc6a18tm1Mca

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC6A18
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S6A18_HUMAN, Q96N87: Membrane; Multi-pass membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    cytosol1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane IEA--
    GO:0016021integral component of membrane ----

    SLC6A18 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC6A18 About    
    See pathways by source

    SuperPathContained pathways About
    1Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transport of inorganic cations/anions and amino acids/oligopeptides0.38
    Transmembrane transport of small molecules0.47
    Amino acid transport across the plasma membrane0.32
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Na+/Cl- dependent neurotransmitter transporters0.00

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for SLC6A18
        Na+/Cl- dependent neurotransmitter transporters
    Amino acid transport across the plasma membrane



    SLC6A18 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC6A18
    Interactions:

        Search GeneGlobe Interaction Network for SLC6A18

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for SLC6A18 (ENSP000003235494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STX1AENSP000002228124STRING: ENSP00000222812
    STX1BENSP000002150954STRING: ENSP00000215095
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport TAS--
    GO:0006836neurotransmitter transport ----
    GO:0006865amino acid transport TAS--
    GO:0055085transmembrane transport TAS--

    SLC6A18 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC6A18 (S6A18)

    1 HMDB Compound for SLC6A18    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC6A18 gene: 
    NM_182632.2  

    Unigene Cluster for SLC6A18:

    Solute carrier family 6, member 18
    Hs.213284  [show with all ESTs]
    Unigene Representative Sequence: BC056757
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000324642(uc003jby.2) ENST00000513607 ENST00000296821
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC6A18
      QuantiFast Probe-based Assays in human, mouse, rat SLC6A18

    Additional mRNA sequence: 

    AK055798.1 AK298257.1 BC056757.1 

    1 DOTS entry:

    DT.75163559 

    11 AceView cDNA sequences:

    BC056757 NM_182632 AK055798 AW300281 BE465178 AW302227 AI633966 BF590014 
    AI889085 AW293344 AA214452 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC6A18 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCGGGTCTG
    SLC6A18 Expression
    About this image


    SLC6A18 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Kidney (Urinary System)
             Proximal Tubule Cells Proximal Tubule
     
     Epithelial Cells
             Proximal Tubule Cells Proximal Tubule
    SLC6A18 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC6A18 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.213284

    UniProtKB/Swiss-Prot: S6A18_HUMAN, Q96N87
    Tissue specificity: Abundantly expressed in kidney, but not in intestine

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SLC6A18 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc6a181 , 5 solute carrier family 6 (neurotransmitter transporter), more1, 5 80.06(n)1
    77.63(a)1
      13 (40.13 cM)5
    225981  NM_001040692.31  NP_001035782.11 
     736617505 
    chicken
    (Gallus gallus)
    Aves LOC1008580921 sodium-dependent neutral amino acid transporter B( more 66.2(n)
    64.41(a)
      100858092  XM_003640787.2  XP_003640835.1 
    zebrafish
    (Danio rerio)
    Actinopterygii slc6a181 solute carrier family 6, member 18 66.49(n)
    61.46(a)
      100141332  NM_001114897.1  NP_001108369.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG108041 CG10804 52.19(n)
    45.16(a)
      31317  NM_166975.2  NP_726868.1 


    ENSEMBL Gene Tree for SLC6A18 (if available)
    TreeFam Gene Tree for SLC6A18 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC6A18 gene
    SLC6A152  SLC6A172  SLC6A202  SLC6A162  SLC6A192  
    Selected SIMAP similar genes for SLC6A18 using alignment to 3 protein entries:     S6A18_HUMAN (see all proteins) (see all similar genes):
    SLC6A15    SLC6A19    5HTT    SLC6A20    DKFZp761I0921    SLC6A4
    DAT1    SLC6A17    SLC6A1    SLC6A3    SLC6A16    SLC6A7
    SLC6A9    SLC6A11    SLC6A14    SLC6A5    SLC6A13    SLC6A12

    SLC6A18 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    S6A18_HUMAN, Q96N87: Genetic variation in SLC6A18 is not a significant predictor for elevated systolic or diastolic blood
    pressure and is not associated with hypertension in the Japanese population


    Selected SNPs for SLC6A18 (see all 761)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2018068211,2
    --1225768(+) ACCTGC/TGTCCT 1 -- int10--------
    rs77043631,2
    C,F,A,H--1225801(+) AGGCCG/ATCTCC 1 -- int113Minor allele frequency- A:0.36MN NA WA CSA EA 772
    rs1927927251,2
    --1225968(+) AGCACA/GGAGGA 1 -- int10--------
    rs1426831171,2
    --1225975(+) AGGATC/GCAGTC 1 -- int10--------
    rs1156751901,2
    C,F--1225985(+) CCCCTC/TGGGGT 1 -- int11Minor allele frequency- T:0.02NA 120
    rs77047281,2
    C,F,A,H--1226051(+) GGGCCG/ACCCTG 1 -- int121Minor allele frequency- A:0.38NS EA NA WA CSA 2343
    rs766198841,2
    C,F--1226071(+) CACACC/TCTACA 1 -- int10--------
    rs125141711,2
    C,F,H--1226105(+) AATGTC/TGTCAG 1 -- int16Minor allele frequency- T:0.25WA NA EA 364
    rs77254641,2
    C,A,H--1226117(+) TCTTTT/AAAGAA 1 -- int112Minor allele frequency- A:0.18WA NA CSA EA 373
    rs1163861541,2
    C--1226133(+) AATCCG/TCTCTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for SLC6A18 (1225470 - 1246304 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SLC6A18 (see all 20):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2729449CNV Deletion23290073
    esv2676695CNV Deletion23128226
    dgv963e201CNV Deletion23290073
    esv2729452CNV Deletion23290073
    esv2729453CNV Deletion23290073
    esv2673732CNV Deletion23128226
    esv2729447CNV Deletion23290073
    esv2729451CNV Deletion23290073
    nsv509044CNV Insertion20534489
    esv1141661CNV Insertion17803354

    Human Gene Mutation Database (HGMD): SLC6A18
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC6A18
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC6A18

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610300    OMIM disorders: --

    UniProtKB/Swiss-Prot: S6A18_HUMAN, Q96N87
  • Note=Genetic variations in SLC6A18 might contribute to the disease phentotype in some individuals with
    iminoglycinuria or hyperglycinuria, that carry variants in SLC36A2, SLC6A19 or SLC6A20

  • 11 diseases for SLC6A18:    
    About MalaCards
    iminoglycinuria    hyperglycinuria    iminoglycinuria, digenic    hypertension
    myocardial infarction    tonsillitis    malaria    multiple myeloma
    myeloma    cerebritis    thyroiditis


    SLC6A18 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC6A18
    Human Genome Epidemiology (HuGE) Navigator: SLC6A18 (4 documents)

    Export disorders for SLC6A18 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC6A18 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with SLC6A18)
        Utopia: connect your pdf to the dynamic
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    1. A nonsense polymorphism (Y319X) of the solute carrier family 6 member 18 (SLC6A18) gene is not associated with hypertension and blood pressure in Japanese. (PubMed id 16340170)1, 2, 4 Eslami B.... Koizumi A. (Tohoku J. Exp. Med. 2006)
    2. Genetic susceptibility to distinct bladder cancer subphenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (Eur. Urol. 2010)
    3. Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3. (PubMed id 19478081)1, 3 Singer D....Verrey F. (J. Biol. Chem. 2009)
    4. Analysis of VNTRs in the solute carrier family 6, member 18 (SLC6A18) and lack of association with hypertension. (PubMed id 18554081)1, 4 Yoon Y.H....Leem S.H. (DNA Cell Biol. 2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Mutations in SLC6A19, encoding B(0)AT1, cause Hartnup disorder. (PubMed id 15286787)1, 2 Kleta R....Koizumi A. (Nat. Genet. 2004)
    8. Association study: SLC6A18 gene and myocardial infarction. (PubMed id 21420947)1 Matsumoto K....Aoi N. (Clin. Biochem. 2011)
    9. Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters. (PubMed id 19033659)2 Broer S.... Rasko J.E. (J. Clin. Invest. 2008)
    10. Amino acid transport across mammalian intestinal and renal epithelia. (PubMed id 18195088)1 BrAPer S. (Physiol. Rev. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 348932 HGNC: 26441 AceView: SLC6A18 Ensembl:ENSG00000164363 euGenes: HUgn348932
    ECgene: SLC6A18 H-InvDB: SLC6A18

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC6A18 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC6A18 gene:
    Search GeneIP for patents involving SLC6A18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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