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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC6A14 Gene

protein-coding   GIFtS: 59
GCID: GC0XP115481

Solute Carrier Family 6 (Amino Acid Transporter), Member...

(Previous names: solute carrier family 6 (neurotransmitter transporter),...)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 6 (Amino Acid Transporter), Member 141 2     Amino Acid Transporter B0+2
Solute Carrier Family 6 (Neurotransmitter Transporter), Member 141 2     Sodium- And Chloride-Dependent Neutral And Basic Amino Acid Transporter
B(0+)2
Amino Acid Transporter ATB0+2 3     Solute Carrier Family 6 Member 143
BMIQ112 5     OBX5

External Ids:    HGNC: 110471   Entrez Gene: 112542   Ensembl: ENSG000000879167   OMIM: 3004445   UniProtKB: Q9UN763   

Export aliases for SLC6A14 gene to outside databases

Previous GC identifers: GC0XP110424 GC0XP112654 GC0XP113582 GC0XP114351 GC0XP115379 GC0XP105105


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC6A14 Gene:
This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride
dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids.
This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked
obesity. A pseudogene of this gene is found on chromosome X.(provided by RefSeq, May 2010)

GeneCards Summary for SLC6A14 Gene: 
SLC6A14 (solute carrier family 6 (amino acid transporter), member 14) is a protein-coding gene. Diseases associated with SLC6A14 include obesity, and ileus, and among its related super-pathways are Amino acid transport across the plasma membrane and Transmembrane transport of small molecules. GO annotations related to this gene include neurotransmitter:sodium symporter activity and amino acid transmembrane transporter activity. An important paralog of this gene is SLC6A6.

UniProtKB/Swiss-Prot: S6A14_HUMAN, Q9UN76
Function: Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline)
in a Na(+)/Cl(-)-dependent manner

Gene Wiki entry for SLC6A14 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_028405.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC6A14 gene promoter:
         STAT1   STAT4   STAT1beta   NF-kappaB   STAT1alpha   POU2F1   POU2F1a   STAT2   STAT3   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC6A14 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC6A14

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC6A14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq23   Ensembl cytogenetic band:  Xq23   HGNC cytogenetic band: Xq23

SLC6A14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC6A14 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP115481:  view genomic region     (about GC identifiers)

Start:
115,567,747 bp from pter      End:
115,592,625 bp from pter
Size:
24,879 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: S6A14_HUMAN, Q9UN76 (See protein sequence)
Recommended Name: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)  
Size: 642 amino acids; 72153 Da
Subcellular location: Membrane; Multi-pass membrane protein
Miscellaneous: Transport inhibited by BCH (2-aminobicyclo-[2.2.1]-heptane-2-carboxylic acid)
Secondary accessions: Q5H942

Explore the universe of human proteins at neXtProt for SLC6A14: NX_Q9UN76

Explore proteomics data for SLC6A14 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UN76

  • SLC6A14 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC6A14 Protein Expression
    REFSEQ proteins: NP_009162.1  
    ENSEMBL proteins: 
     ENSP00000360967  
    Reactome Protein details: Q9UN76
    Human Recombinant Protein Products for SLC6A14: 
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    Cloud-Clone Corp. Proteins for SLC6A14 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--
    GO:0031526brush border membrane IEA--

    SLC6A14 for ontologies           About GeneDecksing



    SLC6A14 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: ATB0,+ 
    Glycine transporter subfamily

    1 InterPro protein domain:
     IPR000175 Na/ntran_symport

    Graphical View of Domain Structure for InterPro Entry Q9UN76

    ProtoNet protein and cluster: Q9UN76

    UniProtKB/Swiss-Prot: S6A14_HUMAN, Q9UN76
    Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A14 subfamily


    SLC6A14 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S6A14_HUMAN, Q9UN76
    Function: Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline)
    in a Na(+)/Cl(-)-dependent manner

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005328neurotransmitter:sodium symporter activity IEA--
    GO:0015171amino acid transmembrane transporter activity TAS10446133
         
    SLC6A14 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SLC6A14:
     Decreased Salmonella enterica   Lamellipodia cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC6A14 
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    SwitchGear 3'UTR luciferase reporter plasmidSLC6A14 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC6A14 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Amino acid and oligopeptide SLC transporters
    Amino acid and oligopeptide SLC transporters0.63
    Transport of inorganic cations/anions and amino acids/oligopeptides0.52
    Amino acid transport across the plasma membrane0.63
    2SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.50
    3Amine compound SLC transporters
    Amine compound SLC transporters0.63
    Na+/Cl- dependent neurotransmitter transporters0.63

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/8        Reactome Pathways for SLC6A14 (see all 8)
        Na+/Cl- dependent neurotransmitter transporters
    Amino acid transport across the plasma membrane
    Amine compound SLC transporters
    SLC-mediated transmembrane transport
    Transmembrane transport of small molecules



    SLC6A14 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC6A14

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003333amino acid transmembrane transport TAS10446133
    GO:0006520cellular amino acid metabolic process TAS10446133
    GO:0006810transport TAS10446133
    GO:0006811ion transport TAS--
    GO:0006836neurotransmitter transport ----

    SLC6A14 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC6A14 (S6A14)

    1 HMDB Compound for SLC6A14    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--

    4 DrugBank Compounds for SLC6A14    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Proline(-)-2-Pyrrolidinecarboxylic acid (see all 6)147-85-3target--17139284 17016423
    D-Serine-- 312-84-5transporter--11846403
    ValaciclovirValaciclovir Hcl (see all 6)124832-27-5transporter--15290873
    ValganciclovirCymeval (see all 2)175865-60-8transporter--15290873

    1 IUPHAR Ligand for SLC6A14 (ATB0,+)    About this table 
    LigandTypeActionAffinityPubmed IDs
    α-methyl-D,L-tryptophan
    InhibitorInhibition3.618522536

    Search CenterWatch for drugs/clinical trials and news about SLC6A14 / S6A14

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC6A14 gene: 
    NM_007231.4  

    Unigene Cluster for SLC6A14:

    Solute carrier family 6 (amino acid transporter), member 14
    Hs.522109  [show with all ESTs]
    Unigene Representative Sequence: NM_007231
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371900(uc011mtm.2 uc004eqi.3) ENST00000463626
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    hsa-miR-548j hsa-miR-29a hsa-miR-374a hsa-miR-548l hsa-miR-186 hsa-miR-548d-5p hsa-miR-548a-5p hsa-miR-23a
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    Additional mRNA sequence: 

    AF151978.1 AK304243.1 AK313390.1 BC093710.1 BC093712.1 

    1 DOTS entry:

    DT.40235975 

    24/35 AceView cDNA sequences (see all 35):

    BQ082831 AA552658 BM856524 BX951397 AF151978 BQ311065 BX642162 CA312866 
    BV184027 BU686768 BQ016954 BX951304 AW192480 BU687102 NM_007231 AW190954 
    CB122805 BE819593 AW812970 BQ378136 BE003214 AI669617 BQ311137 BM826722 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SLC6A14    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                                                                                          
    SP2:                                                                          -               


    ECgene alternative splicing isoforms for SLC6A14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC6A14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATTCTACCA
    SLC6A14 Expression
    About this image


    See SLC6A14 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC6A14

    SOURCE GeneReport for Unigene cluster: Hs.522109

    UniProtKB/Swiss-Prot: S6A14_HUMAN, Q9UN76
    Tissue specificity: Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels
    detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC6A14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SLC6A14 gene from 6/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc6a141 , 5 solute carrier family 6 (neurotransmitter transporter), more1, 5 87.98(n)1
    89.5(a)1
      X (16.78 cM)5
    567741  NM_020049.41  NP_064433.31 
     217148965 
    chicken
    (Gallus gallus)
    Aves SLC6A141 solute carrier family 6 (amino acid transporter), member more 71.14(n)
    74.09(a)
      100857521  XM_003641135.1  XP_003641183.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC6A146
    Transporter
    70(a)
    1 ↔ 1
    GL343403.1(425345-458478)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.234712 Xenopus laevis transcribed sequence with weak similarity more 74.15(n)    BU900196.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1001506651 similar to solute carrier family 6 (neurotransmitter more 64.34(n)
    66.96(a)
      100150665  XM_001923561.2  XP_001923596.1 
    worm
    (Caenorhabditis elegans)
    Secernentea snf-43
    snf-61
    Protein SNF-61 36(a)
    (best of 6)3
    48.1(n)1
    35.29(a)1
      II(12832809-12835718)3
    1917681  NM_065015.41  NP_497416.41 


    ENSEMBL Gene Tree for SLC6A14 (if available)
    TreeFam Gene Tree for SLC6A14 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC6A14 gene
    SLC6A62  SLC6A112  SLC6A122  SLC6A82  SLC6A52  SLC6A32  SLC6A12  SLC6A42  
    SLC6A132  SLC6A72  SLC6A22  SLC6A92  
    18 SIMAP similar genes for SLC6A14 using alignment to 1 protein entry:     S6A14_HUMAN:
    SLC6A5    SLC6A7    SLC6A4    SLC6A2    SLC6A1    SLC6A12
    SLC6A3    SLC6A9    SLC6A11    SLC6A13    SLC6A8    SLC6A6
    SLC6A18    DKFZp761I0921    SLC6A15    SLC6A17    SLC6A19    SLC6A20

    SLC6A14 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for SLC6A14
    PGOHUM00000240281 PGOHUM00000241508 PGOHUM00000241964


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/439 SNPs in SLC6A14 are shown (see all 439)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1828332281,2
    --105115062(-) TTTCAC/TAGGGT 1 -- int10--------
    rs39655551,2
    C,A--105115172(-) ACCAAC/AAATTA 1 -- int12Minor allele frequency- A:0.00NA CSA 3
    rs23350181,2
    C,F,A,H--105115199(-) TAAAAC/TATAAC 2 Y C mis111Minor allele frequency- N:0.00NS EA NA CSA 638
    rs1897661621,2
    --105115381(-) GGCATC/TTGCTT 1 -- int10--------
    rs1854563361,2
    --105115429(-) TGTTGC/TGAGCT 1 -- int10--------
    rs285819571,2
    C--105115471(-) ATATCG/CTAGTG 1 -- int13Minor allele frequency- C:0.00NA 5
    rs1809374041,2
    --105115650(-) TCAACA/TTGCAG 1 -- int10--------
    rs1458401051,2
    C--105115679(-) TTATCC/TAATAA 1 -- int10--------
    rs1918790601,2
    --105115995(-) TGTAGC/TACACT 1 -- int10--------
    rs1439085171,2
    --105116004(-) CATACC/TATCTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for SLC6A14 (115567747 - 115592625 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SLC6A14:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv438153CNV Loss16468122
    nsv526428CNV Gain19592680
    dgv526n21CNV Gain19592680
    nsv523582CNV Gain19592680
    nsv527804CNV Gain19592680


    Human Gene Mutation Database (HGMD): SLC6A14

    Locus Specific Mutation Databases (LSDB): SLC6A14
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC6A14
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC6A14

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300444   
    OMIM disorders: 300306  
    UniProtKB/Swiss-Prot: S6A14_HUMAN, Q9UN76
  • Note=Genetic variations in SLC6A14 may be associated with obesity in some populations, as shown by
    significant differences in allele frequencies between obese and non-obese individuals

  • 8 diseases for SLC6A14:    About MalaCards
    obesity    ileus    ulcerative colitis    cholera
    pneumonia    cystic fibrosis    colorectal cancer    prostatitis


    SLC6A14 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC6A14
    Human Genome Epidemiology (HuGE) Navigator: SLC6A14 (8 documents)

    Export disorders for SLC6A14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC6A14 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with SLC6A14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The SLC6A14 gene shows evidence of association with obesity. (PubMed id 14660752)1, 2, 4, 9 Suviolahti E.... Pajukanta P. (2003)
    2. Cloning and functional expression of a human Na(+) and Cl(-)- dependent neutral and cationic amino acid transporter B(0+). (PubMed id 10446133)1, 2, 3 Sloan J.L. and Mager S. (1999)
    3. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    4. Obesity-related Polymorphisms and Their Associations With the Ability to Regulate Fat Oxidation in Obese Europeans: The NUGENOB Stud y. (PubMed id 19876004)1, 4 Corpeleijn E....Blaak E.E. (2009)
    5. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    6. Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians. (PubMed id 15331564)1, 4 Durand E....Froguel P. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Human solute carrier SLC6A14 is the beta-alanine carrier. (PubMed id 18599538)1, 9 Anderson C.M....Thwaites D.T. (2008)
    9. Multiple apical plasma membrane constituents are assoc iated with susceptibility to meconium ileus in individuals with cystic fibrosis. (PubMed id 22466613)1 Sun L....Strug L.J. (2012)
    10. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11254 HGNC: 11047 AceView: SLC6A14 Ensembl:ENSG00000087916 euGenes: HUgn11254
    ECgene: SLC6A14 H-InvDB: SLC6A14

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC6A14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC6A14 gene:
    Search GeneIP for patents involving SLC6A14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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