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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SLC6A13 Gene

protein-coding GIFtS: 56
GCID: GC12M000329

solute carrier family 6 (neurotransmitter transporter, GABA),...

Explore 1 disease affiliated with
SLC6A13 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 13¹ ²
GAT2¹ ² ³
GAT-2² ³
GABA Transport Protein²
Sodium- And Chloride-Dependent GABA Transporter 2²
Solute Carrier Family 6 Member 13³

External Ids:	HGNC: 11046¹	Entrez Gene: 6540²	Ensembl: ENSG00000010379⁷	OMIM: 615097⁵	UniProtKB: Q9NSD5³

Export aliases for SLC6A13 gene to outside databases

Previous GC identifers: GC12M000184 GC12M000200

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: S6A13_HUMAN, Q9NSD5

Function: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals

summary for SLC6A13:

GABA transporters are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) that

mediate the rapid removal of GABA and maintain low extracellular levels. Four 12-TM domain transporters

(GAT-1, GAT-2, GAT-3 and BGT-1) have been identified and localized to neurons and glia. While GAT-1, GAT-2,

GAT-3 and BGT-1 bind GABA with varying affinities, they share structural motifs including 12-TM domains,

extracellular glycosylation sites and intracellular consensus sites for phosphorylation. A vesicular

transporter (VGAT) has also been identified. This member of the SCL32 family is both structurally and

functionally distinct, containing 10-TM domains and being found in GABAergic and glycinergic neurons. Some

anticonvulsants have been reported to act upon the GABA transporters. There is evidence to suggest that GABA

transporters are linked to epilepsy, affective disorders and schizophrenia.

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000012.11 NC_018923.1 NT_009759.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SLC6A13 gene promoter:
STAT1 C/EBPbeta p53 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 GATA-6 STAT3 NF-kappaB1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC6A13 promoter sequence

Search SABiosciences Chromatin IP Primers for SLC6A13

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC6A13

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.3 Ensembl cytogenetic band: 12p13.33 HGNC cytogenetic band: 12p13.33

SLC6A13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC6A13 gene location

GeneLoc information about chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M000329: view genomic region (about GC identifiers)

Start:	329,789 bp from pter	End:	372,039 bp from pter
Size:	42,251 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: S6A13_HUMAN, Q9NSD5 (See protein sequence)

Recommended Name: Sodium- and chloride-dependent GABA transporter 2

Size: 602 amino acids; 68009 Da

Subcellular location: Membrane; Multi-pass membrane protein

Sequence caution: Sequence=AAF64247.1; Type=Frameshift; Positions=542;

Secondary accessions: B4DJL1 Q8TCC2 Q8WW56

Alternative splicing: 3 isoforms: Q9NSD5-1 Q9NSD5-2 Q9NSD5-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC6A13: NX_Q9NSD5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NSD5

SLC6A13 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001177926.1 NP_001230321.1 NP_057699.2

ENSEMBL proteins:

ENSP00000339260 ENSP00000444606 ENSP00000437386 ENSP00000443466 ENSP00000389316

ENSP00000407104

Reactome Protein details: Q9NSD5
Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SLC6A13

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	--
GO:0005887	integral to plasma membrane	IEA	--
GO:0016021	integral to membrane	--	--

SLC6A13 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for SLC6A13

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SLC6A13 for domains About GeneDecksing

2 InterPro domains/families:

IPR000175 Na/ntran_symport

IPR002981 Na/ntran_symport_GABA_GAT2

Graphical View of Domain Structure for InterPro Entry Q9NSD5

ProtoNet protein and cluster: Q9NSD5

UniProtKB/Swiss-Prot: S6A13_HUMAN, Q9NSD5

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: S6A13_HUMAN, Q9NSD5

Function: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals

Biophysicochemical properties: Kinetic parameters: KM=3.7 uM for GABA; KM=20.2 uM for beta-alanine;

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		hsa-miR-3673 hsa-miR-206 hsa-miR-613 hsa-miR-1
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC6A13

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005328	neurotransmitter:sodium symporter activity	IEA	--
GO:0005332	gamma-aminobutyric acid:sodium symporter activity	IEA	--
GO:0042165	neurotransmitter binding	IEA	--

SLC6A13 for ontologies           About GeneDecksing

Animal Models:
     Mouse knock-out Slc6a13^tm1.2Ncd for SLC6A13
     2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Slc6a13):

homeostasis/metabolism

no phenotypic analysis

SLC6A13 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

SLC-mediated transmembrane transport

	SLC-mediated transmembrane transport	1.00			Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	0.38
	Transmembrane transport of small molecules	0.50

GABA synthesis, release, reuptake and degradation

GABA synthesis, release, reuptake and degradation

1.00

Neurotransmitter Release Cycle

0.53

Transmission across Chemical Synapses

Transmission across Chemical Synapses

1.00

Neuronal System

0.67

Amine compound SLC transporters

Amine compound SLC transporters

1.00

Na+/Cl- dependent neurotransmitter transporters

0.63

Reuptake of GABA

Reuptake of GABA

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for SLC6A13

GABA signaling in brain

5/10 Reactome Pathways for SLC6A13 (see all 10)

	Transmission across Chemical Synapses
	GABA synthesis, release, reuptake and degradation
	Na+/Cl- dependent neurotransmitter transporters
	Amine compound SLC transporters
	Neurotransmitter Release Cycle

1 PharmGKB Pathway for SLC6A13

Benzodiazepine Pathway, Pharmacodynamics

SLC6A13 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SLC6A13

1 Interacting protein for SLC6A13 (Q9NSD5³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBR4	Q5T4S7³	I2D: score=1

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006836	neurotransmitter transport	--	--
GO:0007268	synaptic transmission	TAS	--
GO:0007269	neurotransmitter secretion	TAS	--
GO:0055085	transmembrane transport	TAS	--

SLC6A13 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

SLC6A13 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Compounds for SLC6A13 available from Tocris Bioscience About this table

Compound	Action	CAS #
Riluzole hydrochloride	Glutamate release inhibitor/GABA uptake inhibitor	[1744-22-5]
(�)-Nipecotic acid	GABA uptake inhibitor	[60252-41-7]
beta-Alanine	Endogenous glycine agonist, more selective than taurine (Cat. No. 0209)	[107-95-9]
SKF 89976A hydrochloride	Potent GABA uptake inhibitor. Penetrates blood brain barrier	[85375-15-1]
(S)-SNAP 5114	GABA uptake inhibitor	[157604-55-2]

1 HMDB Compound for SLC6A13 About this table

Compound	Synonyms	CAS #	PubMed Ids
Sodium	Sodium (see all 2)	7440-23-5	--

1 Novoseek chemical compound relationship for SLC6A13 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
gaba	73.7	33	17502375 (5), 10443590 (2), 7854065 (2), 8583006 (2) (see all 12)

Search CenterWatch for drugs/clinical trials and news about SLC6A13 / S6A13

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SLC6A13 gene (3 alternative transcripts):

NM_001190997.2 NM_001243392.1 NM_016615.4

Unigene Clusters for SLC6A13:

Solute carrier family 6 (neurotransmitter transporter, GABA), member 13

Hs.504398 [show with all ESTs], Hs.733878 [show with all ESTs]

Unigene Representative Sequences: NM_016615, DQ786244

12 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000343164(uc009zdj.2 uc001qic.2 uc010sdm.1) ENST00000539668

ENST00000542379 ENST00000543722 ENST00000542947 ENST00000546319 ENST00000536842

ENST00000534887 ENST00000539260 ENST00000542272 ENST00000436453(uc001qid.2)

ENST00000445055(uc010sdl.2)

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		hsa-miR-3673 hsa-miR-206 hsa-miR-613 hsa-miR-1
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Additional cDNA sequence: DQ786244.1

7 DOTS entries:

DT.97839052 DT.40126672 DT.102825094 DT.100744217 DT.406188 DT.121149537 DT.99977092

24/416 AceView cDNA sequences (see all 416):

AA460157 R94969 BM662288 BX474753 BE301184 AU134388 BM686577 AK057703

AI797502 BM310524 AA906265 AA128422 BC053893 AW006851 CA437681 CB158627

AI634822 U25911 N70444 BX106636 BC022392 AW444590 AI146438 AW268369

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SLC6A13 (see all 11) About this scheme

ExUns:	1	^	2a	·	2b	·	2c	^	3a	·	3b	^	4a	·	4b	·	4c	^	5a	·	5b	^	6a	·	6b	·	6c	·	6d	^	7	^	8a	·	8b	^	9	^	10a	·	10b	^	11a	·	11b	^	12a	·	12b	^	13a	·
SP1:							-						-						-		-																		-		-
SP2:							-						-						-		-																		-		-		-
SP3:			-		-		-
SP4:			-		-		-						-
SP5:							-		-		-		-		-		-		-		-

ExUns:	13b	·	13c	^	14	^	15	^	16	^	17a	·	17b
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for SLC6A13

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SLC6A13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAAAGAAGG

About this image

SLC6A13 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

10 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Kidney

Proximal Tubule Cells

Kidney

Adipose

Visceral White Adipose

Adipose

Brain

Kidney

Kidney

Kidney

Kidney

Kidney

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SLC6A13 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC6A13

SOURCE GeneReport for Unigene clusters: Hs.504398 Hs.733878

UniProtKB/Swiss-Prot: S6A13_HUMAN, Q9NSD5

Tissue specificity: Expressed in brain, kidney, lung, liver and testis

SABiosciences Expression via Pathway-Focused PCR Array including SLC6A13:

GABA & Glutamate in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SLC6A13 gene from 5/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100858230¹	sodium- and chloride-dependent GABA transporter 2-like	80.09(n) 85.69(a)		100858230 XM_003640400.1 XP_003640448.1
lizard (Anolis carolinensis)	Reptilia	SLC6A13⁶	--	83(a)	1 ↔ 1	5(11826437-11866069)
African clawed frog (Xenopus laevis)	Amphibia	MGC68654²	hypothetical protein MGC68654	79.5(n)		BC060418.1
zebrafish (Danio rerio)	Actinopterygii	LOC100332592¹	sodium- and chloride-dependent GABA transporter 2-like	73.77(n) 78.69(a)		100332592 XM_002667362.2 XP_002667408.2
worm (Caenorhabditis elegans)	Secernentea	snf-11³	Na(+)/Cl(-)-dependent GABA transporter	48(a) (best of 9)		V(11307950-11311658) --

ENSEMBL Gene Tree for SLC6A13 (if available)
TreeFam Gene Tree for SLC6A13 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SLC6A13 gene

SLC6A6² SLC6A11² SLC6A12² SLC6A14² SLC6A5² SLC6A8² SLC6A1² SLC6A3²

SLC6A4² SLC6A7² SLC6A2² SLC6A9²

18/20 SIMAP similar genes for SLC6A13 using alignment to 4 protein entries: S6A13_HUMAN (see all proteins) (see all similar genes):

SLC6A12 SLC6A11 DAT1 SLC6A1 SLC6A6 SLC6A9

5HTT SLC6A2 SLC6A3 SLC6A8 SLC6A7 SLC6A4

SLC6A5 SLC6A14 SLC6A15 SLC6A19 SLC6A18 SLC6A20

SLC6A13 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for SLC6A13
PGOHUM00000262332

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs186641466^1,2		--	329336(+)	`CTGGGA/GCGTGG`	2	--	ds500¹		0	--	--	--	--
rs191978446^1,2		--	329500(+)	`TCCTTA/CATGCG`	2	--	ds500¹		0	--	--	--	--
rs73038071^1,2	C,	--	329539(+)	`CACAAA/GGNNNN`	2	--	ds500¹		1		NA	120
rs183898038^1,2		--	329679(+)	`ACTCAA/GTGGGG`	2	--	ds500¹		0	--	--	--	--
rs117529140^1,2	F,	--	329703(+)	`GGAGGG/AGCAGG`	2	--	ds500¹		1		NA	120
rs117034619^1,2	F,	--	329767(+)	`CAGAAA/GTCAGA`	2	--	ds500¹		1		NA	120
rs188459854^1,2		--	329792(+)	`GTCAGC/TGGGAA`	2	--	ut3¹		0	--	--	--	--
rs193181125^1,2		--	329826(+)	`GGATGA/GGAGGG`	2	--	ut3¹		0	--	--	--	--
rs184471969^1,2		--	329861(+)	`ACCTAA/CCAGCC`	2	--	ut3¹		0	--	--	--	--
rs77747027^1,2	C,F,	--	329865(+)	`ACCAGC/TCNNNN`	2	--	ut3¹		1		NA	120

HapMap Linkage Disequilibrium report for SLC6A13 (329789 - 372039 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for SLC6A13
3 CNVs: 2965 35068 9201
1 Indel: 45025
Human Gene Mutation Database (HGMD): SLC6A13

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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SLC6A13 for disorders           About GeneDecksing

OMIM gene information: 615097    OMIM disorders: --

1 disease for SLC6A13:    About MalaCards

kidney disease

1 disease from the University of Copenhagen DISEASES database for SLC6A13:

Focal epilepsy

Human Genome Epidemiology (HuGE) Navigator: SLC6A13 (12 documents)

Export disorders for SLC6A13 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for SLC6A13 gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with SLC6A13)

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world of online information

Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2. (PubMed id 17502375)^{1, 2, 9} Christiansen B.... Braeuner-Osborne H. (2007)
Sequence and chromosomal assignment of a human novel cDNA: similarity to gamma-aminobutyric acid transporter. (PubMed id 11824941)^{1, 2, 9} Gong Y.... Minuk G.Y. (2001)
High selectivity of the g-aminobutyric acid transporte r 2 (GAT-2, SLC6A13) revealed by structure-based approach. (PubMed id 22932902)¹ Schlessinger A....Sali A. (2012)
L-type voltage-dependent calcium channel alpha subuni t 1C is a novel candidate gene associated with secondary hyperparathyroidism: a n application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. (PubMed id 20424473)¹ Yokoyama K....Hosoya T. (2010)
Comprehensive copy number variant (CNV) analysis of n euronal pathways genes in psychiatric disorders identifies rare variants within patients. (PubMed id 20398908)¹ Saus E....Estivill X. (2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
New loci associated with kidney function and chronic kidney disease. (PubMed id 20383146)¹ KAPttgen A....Fox C.S. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Genetical genomic determinants of alcohol consumption in rats and humans. (PubMed id 19874574)¹ Tabakoff B....Hoffman P.L. (2009)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 6540	HGNC: 11046	AceView: JARID1AandSLC6A13	Ensembl:ENSG00000010379	euGenes: HUgn6540
ECgene: SLC6A13	H-InvDB: SLC6A13

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SLC6A13	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SLC6A13 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SLC6A13 gene:
Search GeneIP for patents involving SLC6A13

GeneCards and IP:
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