Aliases for SLC5A5 Gene
External Ids for SLC5A5 Gene
This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.[provided by RefSeq, Sep 2009]
GeneCards Summary for SLC5A5 Gene
SLC5A5 (Solute Carrier Family 5 (Sodium/Iodide Cotransporter), Member 5) is a Protein Coding gene. Diseases associated with SLC5A5 include thyroid dyshormonogenesis 1 and neonatal hypothyroidism. Among its related pathways are Metabolism and Metabolism of amino acids and derivatives. GO annotations related to this gene include iodide transmembrane transporter activity and sodium:iodide symporter activity. An important paralog of this gene is SLC5A10.
UniProtKB/Swiss-Prot for SLC5A5 Gene
Mediates iodide uptake in the thyroid gland