V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

SLC5A5 Gene

protein-coding GIFtS: 60

GC19P017843

solute carrier family 5 (sodium iodide symporter), member 5
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
NIS ^¹, ², ³, ⁵
Na(+)/I(-)-symporter ^³

Descriptions
Na(+)/I(-) cotransporter ^³
Sodium-iodide symporter ^², ³
Solute carrier family 5 member 5 ^³
solute carrier family 5 (sodium iodide symporter), member 5 ^²

External Ids
HGNC: 11040¹
Entrez Gene: 6528²
UniProtKB: Q92911³
Ensembl: ENSG00000105641⁷

Search outside databases for aliases for SLC5A5 gene

Previous GC identifers: GC19P018476 GC19P018374 GC19P017827

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for SLC5A5:

The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active

I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2

Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of

iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]).[supplied by OMIM]

UniProtKB/Swiss-Prot: SC5A5_HUMAN, Q92911

Function: Mediates iodide uptake in the thyroid gland

Gene Wiki entry for SLC5A5 (Sodium-iodide_symporter)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SLC5A5 gene

Entrez Gene cytogenetic band: 19p13.2-p12 Ensembl cytogenetic band: 19p13.11 HGNC cytogenetic band: 19p13.2-p12

SLC5A5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P017843: (about GC identifiers)

Start:	17,843,782 bp from pter
End:	17,865,897 bp from pter
Size:	22,116 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000019.8 NT_011295.10

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: SC5A5_HUMAN, Q92911 (See protein sequence)

Recommended Name: Sodium/iodide cotransporter

Size: 643 amino acids; 68666 Da

Subcellular location: Membrane; Multi-pass membrane protein

Secondary accessions: O43702 Q2M335 Q9NYB6

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_000444.1

ENSEMBL proteins:

ENSP00000222248

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Sodium Iodide Symporter)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	TAS	9388506

About this table

Antibodies for SLC5A5:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of SLC5A5
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Sodium Iodide Symporter), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for SLC5A5

Assays for SLC5A5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q92911

ProtoNet protein and cluster: Q92911

1 Blocks protein family: IPB001734 Na+/solute symporter

UniProtKB/Swiss-Prot: SC5A5_HUMAN, Q92911

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SLC5A5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SLC5A5)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000453

Applied Biosystems Silencer® siRNAs for SLC5A5

Sigma-Aldrich siRNA and siRNA Panels for SLC5A5

Sigma-Aldrich shRNA for SLC5A5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000453
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000453
untagged cDNA clone in CMV expression vector: NM_000453

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000453

UniProtKB/Swiss-Prot: SC5A5_HUMAN, Q92911

Function: Mediates iodide uptake in the thyroid gland

Genatlas biochemistry entry for SLC5A5:

solute carrier family 5 member 5,sodium iodide symporter,expressed in thyroid,breast,colon and

ovary,involved in thyroid hormone synthesis and metabolism pathway

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005215	transporter activity	IEA	--
GO:0008507	sodium:iodide symporter activity	IEA	--
GO:0015111	iodide transmembrane transporter activity	TAS	9388506
GO:0015293	symporter activity	IEA	--
GO:0031402	sodium ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for SLC5A5

5/23 Interacting proteins for SLC5A5 (ENSP00000222248³) via UniProtKB, MINT, and/or STRING (see all 23 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NKX2-1	ENSP00000353918³	STRING (score=.99)
PAX8	ENSP00000263334³	STRING (score=.977)
TG	ENSP00000220616³	STRING (score=.968)
TPO	ENSP00000329869³	STRING (score=.967)
TSHR	ENSP00000298171³	STRING (score=.967)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	IEA	--
GO:0006814	sodium ion transport	IEA	--
GO:0015705	iodide transport	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SLC5A5
9 Novoseek chemical compound relationships for SLC5A5 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
sodium iodide	95.34	13	18205108 (3), 10895037 (1), 16500013 (1), 19098211 (1) (see all 7)
iodide	91.26	43	18708479 (5), 12028133 (3), 10487695 (3), 15850642 (3) (see all 20)
perchlorate	70.80	3	15850642 (1), 16500013 (1), 14633711 (1)
iodine	59.96	2	18205108 (1), 14757968 (1)
125i	57.23	2	15347726 (2)
sodium	56.67	7	12028133 (1), 11061512 (1), 10487695 (1), 14757968 (1) (see all 7)
luteolin	53.86	1	15080787 (1)
kaempferol	50.99	1	15080787 (1)
oligonucleotide	3.77	1	9589686 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SLC5A5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SLC5A5)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000453

Sigma-Aldrich siRNA and siRNA Panels for SLC5A5

Sigma-Aldrich shRNA for SLC5A5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000453

REFSEQ mRNAs for SLC5A5 gene:

NM_000453.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000453

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000453
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000453
                                 untagged cDNA clone in CMV expression vector: NM_000453

Additional cDNA sequence:

AF260700.1 BC105047.1 BC105049.1 BX648217.1 D87920.1 U66088.1

2 DOTS entries:

DT.106024 DT.101975701

6 AceView cDNA sequences:

U66088 NM_000453 BX648217 D87920 AF260700 BX509090

highest scoring ESTs for SLC5A5:

U66088 AF260700 D87920 BX648217 NM_000453 BC105047 BC105049 BX509090 AA664278 BF934731

Unigene Cluster for SLC5A5:

Solute carrier family 5 (sodium iodide symporter), member 5

Hs.584804 [show with all ESTs]

Unigene Representative Sequence: NM_000453

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for SLC5A5

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13a	·	13b	^	14	^	15
SP1:
SP2:

About this scheme

ECgene alternative splicing isoforms for SLC5A5

1 Ensembl transcript including schematic representation:

ENST00000222248

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SLC5A5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SLC5A5

¹ / ² / ³

3 probe-sets matching SLC5A5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32459_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	U66088	1.00	1.00	1.00	1
211123_at²^{, 3}	U133-A	1	1.00	1.00	--	--	D87920	0.80	1.00	0.91	1
211123_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GCCCTACTGA

SOURCE GeneReport for Unigene cluster: Hs.584804
Expression variation in blood from EXPOLDB for SLC5A5
UniProtKB/Swiss-Prot: SC5A5_HUMAN, Q92911
Tissue specificity: Expression is primarily in thyroid tissue, but also to a lower extent in
mammary gland and ovary. Expression is reduced in tumors

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SLC5A5 gene from 5/10 species (see all 10 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SLC5A5¹	--	solute carrier family 5 (sodium iodide symporter), more	84.84(n) 85.2(a)	484830 XM_541946.2 XP_541946.2
chimpanzee (Pan troglodytes)	SLC5A5¹	--	solute carrier family 5 (sodium iodide symporter), more	99.53(n) 99.38(a)	468767 XM_524154.2 XP_524154.2
cow (Bos taurus)	SLC5A5¹	--	solute carrier family 5 (sodium iodide symporter), more	85.77(n) 88.61(a)	505310 XM_581578.3 XP_581578.3
rat (Rattus norvegicus)	Slc5a5¹	--	solute carrier family 5 (sodium iodide symporter), more	80.25(n) 84.78(a)	114613 NM_052983.1 NP_443215.1
mouse (Mus musculus)	Slc5a5^{1, 5}	8⁵	solute carrier family 5 (sodium iodide symporter), more^{1, 5}	80.58(n)¹ 84.62(a)¹	114479¹ NM_053248.1¹ NP_444478.1¹ AA615690⁵ AA690196⁵ (see all 13)

About this table Species with no ortholog for SLC5A5

ENSEMBL Gene Tree for SLC5A5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SLC5A5 gene

SLC5A8² SLC5A12²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/168 NCBI SNPs in SLC5A5 are shown (see all 168 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 38)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs8108188^1,2	A,C,F,H	17849825(+)	`CTGCCT/GGCTGT`	1	G/C	mis¹ ese³		8		EU EA WA	838
	rs12327843^1,2	A,C,F,H	17865912(+)	`AGCCCT/CGACGG`	1	--	ut3¹		8		EU EA WA	832
	rs13344000^1,2	A,H	17865901(+)	`TTAGAC/TGCTGC`	1	--	ut3¹		4		EU EA WA	416
	rs11879531^1,2	C	17842091(+)	`CAGCCA/GGCAAC`	1	--	ng5¹		0	--	--	--	--
	rs8103545^1,2	F,H	17847763(+)	`CAGGGC/TGGCAT`	1	G/G	syn¹		4		EU EA WA	418
	rs35209536^1,2	F	17849794(+)	`CAGGTC/TGGCCT`	1	V/V	syn¹		1		NA	76
	rs7257982^1,2	A,C,F,H	17851584(+)	`CACGGG/TTCCCT`	1	--	int¹		4		EU EA WA	418
	rs7255301^1,2	A,C,F,H	17845834(+)	`CTGGCG/AGGCGC`	1	--	int¹		7		EU EA WA NA	556
	rs10417391^1,2	A,C,F,H	17850420(+)	`CAGACA/GAGGGC`	1	--	int¹		8		EU EA WA	832
	rs4808708^1,2	A,C,F,H	17862686(+)	`TCCCCG/ACCTCT`	1	--	int¹		7		EU EA WA NA	550

About this table

HapMap Linkage Disequilibrium images for SLC5A5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 601843 disorders: 274400

UniProtKB/Swiss-Prot: SC5A5_HUMAN, Q92911

Defects in SLC5A5 are the cause of congenital hypothyroidism due to dyshormonogenesis type

1 (CHDH1) [MIM:274400]. CHDH1 is characterized by an inability of the thyroid to maintain a

concentration difference of readily exchangeable iodine between the plasma and the thyroid gland,

leading to congenital hypothyroidism

10 Novoseek disease relationships for SLC5A5 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
congenital hypothyroidism	68.95	2	10895037 (1), 10487695 (1)
thyroid cancer	68.87	5	11061512 (3), 14757968 (1), 18202121 (1)
thyroid carcinoma	56.65	4	11454507 (2), 11061512 (1)
autoimmune thyroid disease	44.68	1	14550956 (1)
thyroid diseases	42.31	6	16121204 (1), 18205108 (1), 11716040 (1)
thyroid papillary carcinoma	39.76	1	17639055 (1)
hypothyroidism	32.14	13	16418213 (2)
tumors	21.77	14	14633711 (2), 18058866 (2), 18676766 (1), 17931047 (1) (see all 8)
cancer	9.42	2	18205108 (1), 17854396 (1)
carcinoma	0.00	3	11454507 (1), 14550956 (1)

About this table

Genatlas disease: SLC5A5

congenital hypothyroidism with goiter,low thyroidal and salivary gland radioiodide uptake

Human Gene Mutation Database: SLC5A5

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/108 PubMed articles for SLC5A5 gene (see all 108 ):

A novel mutation in the sodium/iodide symporter gene in the largest family with iodide transport defect. (PubMed id 10487695)^{1, 3, 4} Kosugi S.... Dean H.J. (1999)
The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)^{3, 4} Grimwood J.... Lucas S.M. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Novel, missense and loss-of-function mutations in the sodium/iodide symporter gene causing iodide transport defect in three Japanese patients. (PubMed id 9745458)^{3, 4} Kosugi S.... Jhiang S.M. (1998)
Congenital hypothyroidism due to mutations in the sodium/iodide symporter: identification of a nonsense mutation producing a downstream cryptic 3' splice site. (PubMed id 9486973)^{3, 4} Pohlenz J....Refetoff S. (1998)
Increased expression of the Na+/I- symporter in cultured human thyroid cells exposed to thyrotropin and in Graves' thyroid tissue. (PubMed id 9329364)^{3, 4} Saito T....Onaya T. (1997)
Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter. (PubMed id 9231811)^{2, 3} Smanik P.A....Jhiang S.M. (1997)
Congenital hypothyroidism caused by a mutation in the Na(+)/I(-) symporter. (PubMed id 9171822)^{3, 4} Fujiwara H....Amino N. (1997)
Cloning of the human sodium iodide symporter. (PubMed id 8806637)^{3, 4} Smanik P.A....Jhiang S.M. (1996)
Identification of cyclic adenosine 3',5'-monophosphate response element modulator as an activator of the human sodium/iodide symporter upstream enhancer. (PubMed id 18202121)^{1, 3} Fenton M.S....Hershman J.M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6528	HGNC: 11040	AceView: SLC5A5	Ensembl:ENSG00000105641	euGenes: HUgn6528
ECgene: SLC5A5	H-InvDB: SLC5A5

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
GeneReviews	http://www.genetests.org/query?gene=SLC5A5

Licensable Technologies for SLC5A5
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for SLC5A5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SLC5A5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SLC5A5		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SLC5A5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Search for Recombinant Proteins
	Search for Antibodies
	Chimera RNAi (SLC5A5)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Sodium Iodide Symporter)
	Antibodies (Sodium Iodide Symporter)

Search OriGene for SLC5A5

Search Tocris compounds for SLC5A5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for SLC5A5

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
SLC5A5 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

SLC5A5 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for SLC5A5

Summaries
for SLC5A5

Genomic Location
for SLC5A5

Proteins
for SLC5A5

Protein Domains/
Families
for SLC5A5

Gene Function
for SLC5A5

Pathways & Interactions
for SLC5A5

Drugs & Compounds
for SLC5A5

Transcripts
for SLC5A5

Expression
for SLC5A5

Orthologs
for SLC5A5

Paralogs
for SLC5A5

SNPs/Variants
for SLC5A5

Disorders & Mutations
for SLC5A5

Medical News
for SLC5A5

Publications
for SLC5A5

Search for SLC5A5

Genome Databases showing SLC5A5

Other Databases showing SLC5A5

Specialized Databases showing SLC5A5

Licensable Technologies
for SLC5A5

Services
for SLC5A5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SLC5A5 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor SLC5A5

Summariesfor SLC5A5

Genomic Locationfor SLC5A5

Proteinsfor SLC5A5

Protein Domains/Familiesfor SLC5A5

Gene Functionfor SLC5A5

Pathways & Interactionsfor SLC5A5

Drugs & Compoundsfor SLC5A5

Transcriptsfor SLC5A5

Expression for SLC5A5

Orthologsfor SLC5A5

Paralogsfor SLC5A5

SNPs/Variantsfor SLC5A5

Disorders & Mutationsfor SLC5A5

Medical Newsfor SLC5A5

Publicationsfor SLC5A5

Search for SLC5A5

Genome Databases showing SLC5A5

Other Databases showing SLC5A5

Specialized Databases showing SLC5A5

Licensable Technologiesfor SLC5A5

Servicesfor SLC5A5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SLC5A5

Summaries
for SLC5A5

Genomic Location
for SLC5A5

Proteins
for SLC5A5

Protein Domains/
Families
for SLC5A5

Gene Function
for SLC5A5

Pathways & Interactions
for SLC5A5

Drugs & Compounds
for SLC5A5

Transcripts
for SLC5A5

Expression
for SLC5A5

Orthologs
for SLC5A5

Paralogs
for SLC5A5

SNPs/Variants
for SLC5A5

Disorders & Mutations
for SLC5A5

Medical News
for SLC5A5

Publications
for SLC5A5

Licensable Technologies
for SLC5A5

Services
for SLC5A5