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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC5A12 Gene

protein-coding   GIFtS: 50
GCID: GC11M026648

Solute Carrier Family 5 (Sodium/Monocarboxylate Cotransporter),...

(Previous names: solute carrier family 5 (sodium/glucose cotransporter),...)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 5 (Sodium/Monocarboxylate Cotransporter), Member
121 2
     Low-Affinity Sodium-Lactate Cotransporter2 3
SMCT22 3 5     Solute Carrier Family 5 Member 122 3
Solute Carrier Family 5 (Sodium/Glucose Cotransporter), Member 121 2     Sodium-Coupled Monocarboxylate Transporter 22
Electroneutral Sodium Monocarboxylate Cotransporter2 3     Sodium-Iodide Related Cotransporter2

External Ids:    HGNC: 287501   Entrez Gene: 1599632   Ensembl: ENSG000001489427   OMIM: 6124555   UniProtKB: Q1EHB43   

Export aliases for SLC5A12 gene to outside databases

Previous GC identifer: GC11M026386


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC5A12 Gene:
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption
of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the
proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal
proximal tubule (Gopal et al., 2007 (PubMed 17692818)).(supplied by OMIM, Dec 2008)

GeneCards Summary for SLC5A12 Gene: 
SLC5A12 (solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12) is a protein-coding gene. Diseases associated with SLC5A12 include hyperuricemia, and pneumonia. GO annotations related to this gene include symporter activity. An important paralog of this gene is SLC5A8.

UniProtKB/Swiss-Prot: SC5AC_HUMAN, Q1EHB4
Function: Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter.
Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate,
nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of
reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May
play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of
lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_009237.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC5A12 gene promoter:
         TBP   E2F-3a   E2F-4   E2F-5   E2F-2   HNF-1A   E2F-1   E2F   Nkx6-1   HNF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC5A12 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC5A12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC5A12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p14.2   Ensembl cytogenetic band:  11p14.2   HGNC cytogenetic band: 11p14.2

SLC5A12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC5A12 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M026648:  view genomic region     (about GC identifiers)

Start:
26,688,566 bp from pter      End:
26,744,974 bp from pter
Size:
56,409 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SC5AC_HUMAN, Q1EHB4 (See protein sequence)
Recommended Name: Sodium-coupled monocarboxylate transporter 2  
Size: 618 amino acids; 67647 Da
Subcellular location: Apical cell membrane; Multi-pass membrane protein. Note=Detected at the brush border
membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity)
Secondary accessions: Q86UC7
Alternative splicing: 2 isoforms:  Q1EHB4-1   Q1EHB4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC5A12: NX_Q1EHB4

Explore proteomics data for SLC5A12 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q1EHB4

  • SLC5A12 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC5A12 Protein Expression
    REFSEQ proteins: NP_848593.2  
    ENSEMBL proteins: 
     ENSP00000379326   ENSP00000436011   ENSP00000280467   ENSP00000435053  

    Human Recombinant Protein Products for SLC5A12: 
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC5A12 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--
    GO:0016324apical plasma membrane IEA--

    SLC5A12 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: SMCT2 
    Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters

    2 InterPro protein domains:
     IPR019900 Na/solute_symporter_subgr
     IPR001734 Na/solute_symporter

    Graphical View of Domain Structure for InterPro Entry Q1EHB4

    ProtoNet protein and cluster: Q1EHB4

    1 Blocks protein domain: IPB001734 Na+/solute symporter

    UniProtKB/Swiss-Prot: SC5AC_HUMAN, Q1EHB4
    Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family


    SLC5A12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SC5AC_HUMAN, Q1EHB4
    Function: Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter.
    Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate,
    nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of
    reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May
    play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of
    lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity)
    Enzyme regulation: Cotransport of monocarboxylates and nicotinate strongly inhibited by ibuprofen, fenoprofen and
    ketoprofen

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity ----
    GO:0015293symporter activity IEA--
         
    SLC5A12 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC5A12 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC5A12 
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    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC5A12 (see all 14):
    hsa-miR-299-5p hsa-miR-203 hsa-miR-875-3p hsa-miR-576-5p hsa-miR-3606 hsa-miR-374b hsa-miR-4272 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidSLC5A12 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC5A12


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC5A12

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0006814sodium ion transport IEA--
    GO:0055085transmembrane transport ----

    SLC5A12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC5A12 (SC5AC)

    1 HMDB Compound for SLC5A12    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--

    Search CenterWatch for drugs/clinical trials and news about SLC5A12 / SC5AC

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC5A12 gene: 
    NM_178498.3  

    Unigene Cluster for SLC5A12:

    Solute carrier family 5 (sodium/glucose cotransporter), member 12
    Hs.148907  [show with all ESTs]
    Unigene Representative Sequence: NM_178498
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396005(uc001mra.2 uc001mrb.2) ENST00000527405 ENST00000280467(uc001mrc.4)
    ENST00000533617 ENST00000528822
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC5A12
    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC5A12 (see all 14):
    hsa-miR-299-5p hsa-miR-203 hsa-miR-875-3p hsa-miR-576-5p hsa-miR-3606 hsa-miR-374b hsa-miR-4272 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidSLC5A12 3' UTR sequence
    Inhib. RNA
    Products:
         
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC5A12
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC5A12

    Additional mRNA sequence: 

    AL049270.1 AY299482.1 BC029048.1 BC049207.1 

    6 DOTS entries:

    DT.201196  DT.87015906  DT.95362979  DT.95147924  DT.120698716  DT.120717595 

    24/69 AceView cDNA sequences (see all 69):

    AI222681 BF115123 AI634654 AI474636 AI913587 BF740012 BE048940 AI478641 
    AW272244 AI493090 NM_178498 BM924715 AI493025 AI433307 AI241284 BC041454 
    BX099432 AI792874 AI522321 AI821961 AA994816 AI566076 BI764390 AW614338 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SLC5A12    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:              -     -                                                           -                                       
    SP2:              -                                                                                                         
    SP3:                    -                                                                                                   


    ECgene alternative splicing isoforms for SLC5A12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC5A12 expression in normal human tissues (normalized intensities)      SLC5A12 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC5A12 Expression
    About this image


    SLC5A12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 2 entries
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
     
     Intestine (Gastrointestinal Tract)
             ileum   
     
     Paraxial Mesoderm (Gastrulation Derivatives)
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
     
     Ovary (Reproductive System)
             oocyte   
     
     Endothelium (Cardiovascular System)
             Embryoid bodies ( Two-step protocol for endothelial differentiation by embryoid...

    See SLC5A12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC5A12

    SOURCE GeneReport for Unigene cluster: Hs.148907
        SABiosciences Custom PCR Arrays for SLC5A12
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC5A12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SLC5A12 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc5a121 , 5 solute carrier family 5 (sodium/glucose cotransporter), more1, 5 82.85(n)1
    82.63(a)1
      2 (56.75 cM)5
    2416121  NM_001003915.21  NP_001003915.11 
     1105972985 
    chicken
    (Gallus gallus)
    Aves SLC5A121 solute carrier family 5 (sodium/glucose cotransporter), more 70.25(n)
    72.31(a)
      431338  XM_428889.1  XP_428889.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC5A126
    solute carrier family 5 (sodium/glucose cotranspor...
    73(a)
    1 ↔ 1
    GL343240.1(865980-899427)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc640372 hypothetical protein MGC64037 76.06(n)   393339  BC053215.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG67236
    CG96576
    (see all 12)
    --
    32(a)
    30(a)
    (see all 12)
    many ↔ many
    many ↔ many
    (see all 12)
    3R(7241940-7244389)
    X(7312628-7315672)
    worm
    (Caenorhabditis elegans)
    Secernentea ZK822.51 Protein ZK822.5 44.44(n)
    33.72(a)
      178127  NM_001047602.3  NP_001041067.1 


    ENSEMBL Gene Tree for SLC5A12 (if available)
    TreeFam Gene Tree for SLC5A12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC5A12 gene
    SLC5A82  SLC5A12  SLC5A42  SLC5A52  SLC5A112  SLC5A92  SLC5A102  SLC5A32  
    SLC5A22  SLC5A62  
    3 SIMAP similar genes for SLC5A12 using alignment to 4 protein entries:     SC5AC_HUMAN (see all proteins):
    SLC5A8    SLC5A5    SLC5A6

    SLC5A12 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1314 SNPs in SLC5A12 are shown (see all 1314)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1453739371,2
    Cuntested126734223(+) ATAGCA/GAACTG 2 R C mis10--------
    rs1842359781,2
    C--26688275(+) ATCTTG/TCTCCA 1 -- ds50010--------
    rs1887382881,2
    --26688318(+) CAGCCC/TGACAC 1 -- ds50010--------
    rs1931829791,2
    --26688407(+) TTTGAA/GACACC 1 -- ds50010--------
    rs1382873981,2
    --26688411(+) AAACAC/TCAAAG 1 -- ds50010--------
    rs71032161,2
    C,F,A,H--26688444(+) TGTGCA/GTGTTT 1 -- ds50015Minor allele frequency- G:0.02NS EA WA 538
    rs1829611441,2
    --26688497(+) GGAGAC/TTGGGG 1 -- ds50010--------
    rs1872603941,2
    --26688553(+) AAAATA/CTACCC 1 -- ds50010--------
    rs1917262471,2
    --26688592(+) ACATTC/TTATTA 1 -- ut310--------
    rs1438954461,2
    C--26688627(+) GTGTA-/CCCATT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC5A12 (26688566 - 26744974 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SLC5A12:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1423248CNV Insertion17803354
    nsv39059CNV Loss16902084
    nsv819331CNV Gain19587683

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612455    OMIM disorders: --

    2 diseases for SLC5A12:    About MalaCards
    hyperuricemia    pneumonia

    1 disease from the University of Copenhagen DISEASES database for SLC5A12:
    Hyperuricemia

    SLC5A12 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC5A12

    Export disorders for SLC5A12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC5A12 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SLC5A12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney. (PubMed id 17692818)1, 2 Gopal E.... Prasad P.D. (2007)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. Genome-wide association with diabetes-related traits in the Framingham Heart Study. (PubMed id 17903298)4 Meigs J.B....Dupuis J. (2007)
    4. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PubMed id 17903307)4 Wilk J.B....O'Connor G.T. (2007)
    5. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
    6. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. (PubMed id 11022011)4 Ober C....Cox N.J. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 159963 HGNC: 28750 AceView: SLC5A12 Ensembl:ENSG00000148942 euGenes: HUgn159963
    ECgene: SLC5A12 H-InvDB: SLC5A12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC5A12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC5A12 gene:
    Search GeneIP for patents involving SLC5A12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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