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SLC5A12 Gene

protein-coding   GIFtS: 50
GCID: GC11M026648

Solute Carrier Family 5 (Sodium/Monocarboxylate Cotransporter),...

(Previous names: solute carrier family 5 (sodium/glucose cotransporter),...)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 5 (Sodium/Monocarboxylate Cotransporter), Member
121 2
     Low-Affinity Sodium-Lactate Cotransporter2 3
SMCT22 3 5     Solute Carrier Family 5 Member 122 3
Solute Carrier Family 5 (Sodium/Glucose Cotransporter), Member 121 2     Sodium-Coupled Monocarboxylate Transporter 22
Electroneutral Sodium Monocarboxylate Cotransporter2 3     Sodium-Iodide Related Cotransporter2

External Ids:    HGNC: 287501   Entrez Gene: 1599632   Ensembl: ENSG000001489427   OMIM: 6124555   UniProtKB: Q1EHB43   

Export aliases for SLC5A12 gene to outside databases

Previous GC identifer: GC11M026386


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC5A12 Gene:
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption
of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the
proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal
proximal tubule (Gopal et al., 2007 (PubMed 17692818)).(supplied by OMIM, Dec 2008)

GeneCards Summary for SLC5A12 Gene:
SLC5A12 (solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12) is a protein-coding gene. GO annotations related to this gene include symporter activity. An important paralog of this gene is ENSG00000272962.

UniProtKB/Swiss-Prot: SC5AC_HUMAN, Q1EHB4
Function: Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter.
Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate,
nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of
reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May
play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of
lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC5A12 gene promoter:
         TBP   E2F-3a   E2F-4   E2F-5   E2F-2   HNF-1A   E2F-1   E2F   Nkx6-1   HNF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC5A12 promoter sequence
   Search Chromatin IP Primers for SLC5A12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC5A12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p14.2   Ensembl cytogenetic band:  11p14.2   HGNC cytogenetic band: 11p14.2

SLC5A12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC5A12 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M026648:  view genomic region     (about GC identifiers)

Start:
26,688,566 bp from pter      End:
26,744,974 bp from pter
Size:
56,409 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SC5AC_HUMAN, Q1EHB4 (See protein sequence)
Recommended Name: Sodium-coupled monocarboxylate transporter 2  
Size: 618 amino acids; 67647 Da
Secondary accessions: Q86UC7
Alternative splicing: 2 isoforms:  Q1EHB4-1   Q1EHB4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC5A12: NX_Q1EHB4

Explore proteomics data for SLC5A12 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn480
  • Modification sites at PhosphoSitePlus

  • See SLC5A12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_848593.2  
    ENSEMBL proteins: 
     ENSP00000379326   ENSP00000436011   ENSP00000280467   ENSP00000435053  

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    antibodies-online kits for SLC5A12 (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: SMCT2
    Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters

    2 InterPro protein domains:
     IPR019900 Na/solute_symporter_subgr
     IPR001734 Na/solute_symporter

    Graphical View of Domain Structure for InterPro Entry Q1EHB4

    ProtoNet protein and cluster: Q1EHB4

    1 Blocks protein domain: IPB001734 Na+/solute symporter

    UniProtKB/Swiss-Prot: SC5AC_HUMAN, Q1EHB4
    Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family


    Find genes that share domains with SLC5A12           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SC5AC_HUMAN, Q1EHB4
    Function: Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter.
    Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate,
    nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of
    reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May
    play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of
    lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity)
    Enzyme regulation: Cotransport of monocarboxylates and nicotinate strongly inhibited by ibuprofen, fenoprofen and
    ketoprofen

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity ----
    GO:0015293symporter activity IEA--
         
    Find genes that share ontologies with SLC5A12           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for SLC5A12

    miRNA
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    hsa-miR-299-5p hsa-miR-203 hsa-miR-875-3p hsa-miR-576-5p hsa-miR-3606 hsa-miR-374b hsa-miR-4272 hsa-miR-374a
    SwitchGear 3'UTR luciferase reporter plasmidSLC5A12 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SC5AC_HUMAN, Q1EHB4: Apical cell membrane; Multi-pass membrane protein. Note=Detected at the brush border
    membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0016324apical plasma membrane IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with SLC5A12           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC5A12
    Interactions:

        Search GeneGlobe Interaction Network for SLC5A12

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0006814sodium ion transport IEA--
    GO:0055085transmembrane transport ----

    Find genes that share ontologies with SLC5A12           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC5A12 (SC5AC)

    1 HMDB Compound for SLC5A12    About this table
    CompoundSynonyms CAS #PubMed Ids
    SodiumSodium (see all 2)7440-23-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC5A12 gene: 
    NM_178498.3  

    Unigene Cluster for SLC5A12:

    Solute carrier family 5 (sodium/glucose cotransporter), member 12
    Hs.148907  [show with all ESTs]
    Unigene Representative Sequence: NM_178498
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396005(uc001mra.2 uc001mrb.2) ENST00000527405 ENST00000280467(uc001mrc.4)
    ENST00000533617 ENST00000528822
    miRNA
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    hsa-miR-299-5p hsa-miR-203 hsa-miR-875-3p hsa-miR-576-5p hsa-miR-3606 hsa-miR-374b hsa-miR-4272 hsa-miR-374a
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC5A12
      QuantiFast Probe-based Assays in human, mouse, rat SLC5A12

    Additional mRNA sequence: 

    AL049270.1 AY299482.1 BC029048.1 BC049207.1 

    6 DOTS entries:

    DT.201196  DT.87015906  DT.95362979  DT.95147924  DT.120698716  DT.120717595 

    Selected AceView cDNA sequences (see all 69):

    BF740012 AI474636 BE048940 AW272244 AI913587 AI222681 AI478641 AI493090 
    BF115123 AI634654 BM924715 BI764390 BC041454 AI493025 AI821961 AI522321 
    BE048682 AI733515 AI522047 AA872711 AI261569 AI792225 BX099432 AW001704 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SLC5A12    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:              -     -                                                           -                                       
    SP2:              -                                                                                                         
    SP3:                    -                                                                                                   


    ECgene alternative splicing isoforms for SLC5A12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC5A12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SLC5A12 Expression
    About this image


    SLC5A12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 2 entries
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
     
     Paraxial Mesoderm (Gastrulation Derivatives)
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
     
     NULL (Uncategorized)
             Vascular endothelial growth factor-induced embryoid bodies
     
     Mesoderm (Gastrulation Derivatives)
             PureStem 7SMOO32, NCr-fac & Meso Progenitor
     
     Kidney (Urinary System)
    SLC5A12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC5A12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.148907
        Custom PCR Arrays for SLC5A12
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SLC5A12 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc5a121 , 5 solute carrier family 5 (sodium/glucose cotransporter), more1, 5 84.84(n)1
    85.28(a)1
      2 (56.75 cM)5
    2416121  NM_001177624.11  NP_001171095.11 
     1105972985 
    chicken
    (Gallus gallus)
    Aves SLC5A121 solute carrier family 5 (sodium/glucose cotransporter), more 70.52(n)
    72.48(a)
      431338  XM_428889.2  XP_428889.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC5A126
    solute carrier family 5 (sodium/monocarboxylate co...
    73(a)
    1 ↔ 1
    GL343240.1(865980-899427)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia slc5a121 solute carrier family 5 (sodium/glucose cotransporter), more 68.34(n)
    72.73(a)
      100495641  XM_004913592.1  XP_004913649.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc640372 hypothetical protein MGC64037 76.06(n)   393339  BC053215.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG104441 CG10444 49.49(n)
    40.58(a)
      37294  NM_137621.2  NP_611465.2 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK822.51 ZK822.5 44.42(n)
    33.65(a)
      178127  NM_001047602.4  NP_001041067.1 


    ENSEMBL Gene Tree for SLC5A12 (if available)
    TreeFam Gene Tree for SLC5A12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC5A12 gene
    ENSG000002729622  SLC5A82  SLC5A12  SLC5A42  SLC5A52  SLC5A112  SLC5A92  SLC5A102  
    SLC5A32  SLC5A22  SLC5A62  
    3 SIMAP similar genes for SLC5A12 using alignment to 4 protein entries:     SC5AC_HUMAN (see all proteins):
    SLC5A8    SLC5A5    SLC5A6

    Find genes that share paralogs with SLC5A12           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC5A12 (see all 1314)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1453739371,2
    Cuntested126734223(+) ATAGCA/GAACTG 2 R C mis10--------
    rs1842359781,2
    C--26688275(+) ATCTTG/TCTCCA 1 -- ds50010--------
    rs1887382881,2
    --26688318(+) CAGCCC/TGACAC 1 -- ds50010--------
    rs1931829791,2
    --26688407(+) TTTGAA/GACACC 1 -- ds50010--------
    rs1382873981,2
    --26688411(+) AAACAC/TCAAAG 1 -- ds50010--------
    rs71032161,2
    C,F,A,H--26688444(+) TGTGCA/GTGTTT 1 -- ds50015Minor allele frequency- G:0.02NS EA WA 538
    rs1829611441,2
    --26688497(+) GGAGAC/TTGGGG 1 -- ds50010--------
    rs1872603941,2
    --26688553(+) AAAATA/CTACCC 1 -- ds50010--------
    rs1917262471,2
    --26688592(+) ACATTC/TTATTA 1 -- ut310--------
    rs1438954461,2
    C--26688627(+) GTGTA-/CCCATT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SLC5A12 (26688566 - 26744974 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SLC5A12:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1423248CNV Insertion17803354
    nsv39059CNV Loss16902084
    nsv819331CNV Gain19587683

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC5A12
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612455    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for SLC5A12:
    Hyperuricemia

    Find genes that share disorders with SLC5A12           About GenesLikeMe

    Genetic Association Database (GAD): SLC5A12

    Export disorders for SLC5A12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC5A12 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with SLC5A12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney. (PubMed id 17692818)1, 2 Gopal E.... Prasad P.D. (Biochim. Biophys. Acta 2007)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    4. Genome-wide association with diabetes-related traits in the Framingham Heart Study. (PubMed id 17903298)4 Meigs J.B....Dupuis J. (BMC Med. Genet. 2007)
    5. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PubMed id 17903307)4 Wilk J.B....O'Connor G.T. (BMC Med. Genet. 2007)
    6. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (Nature 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)
    9. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. (PubMed id 11022011)4 Ober C....Cox N.J. (Am. J. Hum. Genet. 2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 159963 HGNC: 28750 AceView: SLC5A12 Ensembl:ENSG00000148942 euGenes: HUgn159963
    ECgene: SLC5A12 H-InvDB: SLC5A12

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SLC5A12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC5A12 gene:
    Search GeneIP for patents involving SLC5A12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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