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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC52A3 Gene

protein-coding   GIFtS: 49
GCID: GC20M000741

solute carrier family 52, riboflavin transporter, member...

(Previous name: chromosome 20 open reading frame 54 )
(Previous symbol: C20orf54)
 Explore 19 diseases affiliated with
SLC52A3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC52A3    

Aliases
for SLC52A3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 52, Riboflavin Transporter, Member 31 2     Riboflavin Transporter 22 3
C20orf541 2 3 5     BVVLS2 5
HRFT21     Chromosome 20 Open Reading Frame 541
RFT22 3 5     BVVLS12
RFVT31 2     Solute Carrier Family 52 Member 32
BA371L19.11     

External Ids:    HGNC: 161871   Entrez Gene: 1132782   Ensembl: ENSG000001012767   OMIM: 6133505   UniProtKB: Q9NQ403   

Export aliases for SLC52A3 gene to outside databases


Summaries
for SLC52A3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SLC52A3:
This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role
in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell
surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van
Laere syndrome and Fazio-Londe disease. (provided by RefSeq, Mar 2012)

UniProtKB/Swiss-Prot: S52A3_HUMAN, Q9NQ40
Function: Riboflavin transporter. Riboflavin transport is Na(+)-independent but moderately pH-sensitive. Activity is
strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN) and flavin adenine
dinucleotide (FAD), and to a lesser extent by amiloride

Gene Wiki entry for SLC52A3 (C20orf54)


Genomic Views
for SLC52A3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011387.8  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for SLC52A3
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SLC52A3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC52A3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p13   HGNC cytogenetic band: 20p13

SLC52A3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC52A3 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M000741:  view genomic region     (about GC identifiers)

Start:
 740,724 bp from pter      End:
 749,228 bp from pter
Size:
 8,505 bases      Orientation:
 minus strand

Proteins
for SLC52A3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: S52A3_HUMAN, Q9NQ40 (See protein sequence)
Recommended Name: Solute carrier family 52, riboflavin transporter, member 3  
Size: 469 amino acids; 50805 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Caution: It is uncertain whether Met-1 or Met-5 is the initiator
Secondary accessions: A8K6P1 Q5W1A0 Q5W1A1 Q8NCL7 Q96GD5
Alternative splicing: 2 isoforms:  Q9NQ40-1   Q9NQ40-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC52A3: NX_Q9NQ40

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NQ40

    • SLC52A3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_212134.3  
    ENSEMBL proteins: 
     ENSP00000217254   ENSP00000371370  

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    Uscn Proteins for SLC52A3

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane IDA--


    SLC52A3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SLC52A3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC52A3 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009357 Endogenous_retrovirus_rcpt

    Graphical View of Domain Structure for InterPro Entry Q9NQ40

    ProtoNet protein and cluster: Q9NQ40

    UniProtKB/Swiss-Prot: S52A3_HUMAN, Q9NQ40
    Similarity: Belongs to the riboflavin transporter family


    Function
    for SLC52A3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: S52A3_HUMAN, Q9NQ40
    Function: Riboflavin transporter. Riboflavin transport is Na(+)-independent but moderately pH-sensitive. Activity is
    strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN) and flavin adenine
    dinucleotide (FAD), and to a lesser extent by amiloride
    Biophysicochemical properties: Kinetic parameters: KM=0.98 uM for riboflavin;

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    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0032217riboflavin transporter activity IDA--


    SLC52A3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SLC52A3:
     Increased HPV18 LCR reporter a 

    Animal Models:
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Slc52a3):
     hematopoietic system  mortality/aging 

    SLC52A3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SLC52A3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Vitamin digestion and absorption
    		Vitamin digestion and absorption1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for SLC52A3):
        Vitamin digestion and absorption


    SLC52A3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC52A3

    2 Interacting proteins for SLC52A3 (Q9NQ403) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIP13Q156453I2D: score=3 
    HOMER2Q9NSB83I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007605sensory perception of sound IMP--
    GO:0032218riboflavin transport IDA--
    GO:0034605cellular response to heat IEA--


    SLC52A3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC52A3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC52A3
    Search CenterWatch for drugs/clinical trials and news about SLC52A3 / S52A3 

    Transcripts
    for SLC52A3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC52A3 gene: 
    NM_033409.3  

    Unigene Cluster for SLC52A3:

    Solute carrier family 52, riboflavin transporter, member 3
    Hs.283865  [show with all ESTs]
    Unigene Representative Sequence: NM_033409
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000217254(uc002wed.4) ENST00000381944(uc002wee.2) ENST00000473664
    ENST00000488495

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    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AK291706.1 BC009750.2 JX478249.1 

    5 DOTS entries:

    DT.91729600  DT.442493  DT.92066299  DT.120812592  DT.100722324 

    24/51 AceView cDNA sequences (see all 51):

    BX102356 BX350153 AL547105 AW082342 AI638176 NM_033409 BC009750 BX359203 
    AI799867 AK074650 AI492407 CB306944 AA903862 AA722541 CD635112 AI377348 
    AL044006 AW189419 CD635108 AW438810 AI804916 AW295908 BE563706 BE222918 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for SLC52A3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6
    SP1:              -                           
    SP2:              -                           
    SP3:                                          


    ECgene alternative splicing isoforms for SLC52A3

    Expression
    for SLC52A3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC52A3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGAGCCCCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SLC52A3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyProximal TubuleProximal Tubule CellsKidney
    KidneyEpithelial TubuleKidney
    KidneyMetanephrosKidney
    KidneyProximal TubuleKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Line H9 (WA09) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass

    See SLC52A3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC52A3

    SOURCE GeneReport for Unigene cluster: Hs.283865

    UniProtKB/Swiss-Prot: S52A3_HUMAN, Q9NQ40
    Tissue specificity: Predominantly expressed in testis. Highly expressed in small intestine and prostate

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    In Situ
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    Orthologs
    for SLC52A3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for SLC52A3 gene from 6/24 species (see all 24)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves C20H20orf541 chromosome 20 open reading frame, human C20orf54 67.42(n)
    60.63(a)    		   419270  XM_417443.3  XP_417443.3 
    lizard
    (Anolis carolinensis)    		 Reptilia C20orf546
    --
    		 --
    		 56(a)
    48(a)
    		 1 ↔ 1
    possible ortholog
    		 GL343346.1(307694-313760)
    AAWZ02038103(2677-5860)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia 1420061962   -- 77.54(n)    142006196 
    zebrafish
    (Danio rerio)    		 Actinopterygii slc52a31 solute carrier family 52, riboflavin transporter, member more 60.36(n)
    58.54(a)    		   678609  NM_001040357.1  NP_001035447.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG115761 CG11576 53.06(n)
    41.32(a)    		   43756  NM_143644.2  NP_651901.3 
    worm
    (Caenorhabditis elegans)    		 Secernentea Y47D7A.141 Protein Y47D7A.14 44.18(n)
    35.89(a)    		   178842  NM_071826.3  NP_504227.3 


    ENSEMBL Gene Tree for SLC52A3 (if available)
    TreeFam Gene Tree for SLC52A3 (if available) 

    Paralogs
    for SLC52A3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC52A3 gene
    SLC52A22  SLC52A12  
    2 SIMAP similar genes for SLC52A3 using alignment to 2 protein entries:     S52A3_HUMAN (see all proteins):
    SLC52A1    SLC52A2

    SLC52A3 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC52A3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/287 NCBI SNPs in SLC52A3 are shown (see all 287)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs61333711,2
    		H--691713(+) ACATCC/TTTAAG 1 -- int14Minor allele frequency- T:0.00NS EA 420
    rs454819051,2
    		C,F,--692075(+) TGCTGG/AGATTA 1 -- int13Minor allele frequency- A:0.33NA 6
    rs10530181,2
    		C,F,H,--692246(-) CCAGAC/GATGCA 1 -- ut31 ese311Minor allele frequency- G:0.09MN NS EA NA WA 846
    rs769984611,2
    		F,--692516(+) GGAGAG/AAGGGC 1 -- ut311Minor allele frequency- A:0.02WA 118
    rs1133422501,2
    		--692584(+) TACTAT/CGATGG 1 -- ut311Minor allele frequency- C:0.00CSA 1
    rs730697091,2
    		C,--692799(+) TAACAC/TCCTTG 1 -- ut310--------
    rs133399331,2
    		C,F,H,--693665(+) ACCCCG/ACTCGC 1 -- int1 ese35Minor allele frequency- A:0.01NS EA WA 532
    rs764419121,2
    		C,F,--694156(+) TTCTAC/TTGTTT 1 -- int11Minor allele frequency- T:0.03NA 120
    rs60857191,2
    		H--694165(+) ttaagC/AtgAGA 1 -- int14Minor allele frequency- A:0.00NS EA 420
    rs61175071,2
    		H--694287(+) TCCTCC/TTGCAA 1 -- int14Minor allele frequency- T:0.00NS EA 420

    HapMap Linkage Disequilibrium report for SLC52A3 (740724 - 749228 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC52A3: --
    Human Gene Mutation Database (HGMD): SLC52A3

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC52A3
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC52A3

    Disorders / Diseases
    for SLC52A3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC52A3 for disorders           About GeneDecksing

    OMIM gene information: 613350   
    OMIM disorders: 211530  211500  
    UniProtKB/Swiss-Prot: S52A3_HUMAN, Q9NQ40
  • Defects in SLC52A3 are the cause of Brown-Vialetto-Van Laere syndrome type 1 (BVVLS1) [MIM:211530]. A rare
    • autosomal recessive neurologic disorder characterized by sensorineural hearing loss and a variety of cranial nerve
    palsies, which develop over a relatively short period of time in a previously healthy individual. Sensorineural
    hearing loss may precede the neurological signs. The course is invariably progressive, but the rate of decline is
    variable within and between families. With disease evolution, long tract signs, lower motor neuron signs, cerebellar
    ataxia, and lower cranial nerve (III-VI) palsies develop, giving rise to a complex picture resembling amyotrophic
    lateral sclerosis. Diaphragmatic weakness and respiratory compromise are some of the most distressing features,
    leading to recurrent chest infections and respiratory failure, which are often the cause of patients' demise
  • Defects in SLC52A3 are the cause of Fazio-Londe disease (FALOND) [MIM:211500]. A rare neurological disease
    • characterized by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. It may
    present in childhood with severe neurological deterioration with hypotonia, respiratory insufficiency leading to
    premature death, or later in life with bulbar weakness which progresses to involve motor neurons throughout the
    neuroaxis. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations
    of the tongue and facial muscles

    19 diseases for SLC52A3:    About MalaCards
    brown-vialetto-van laere syndrome    fazio londe syndrome    sensorineural hearing loss    cranial nerve palsy
    amyotrophic lateral sclerosis    dysphagia    esophageal squamous cell carcinoma    hearing loss
    cerebellar ataxia    lateral sclerosis    respiratory failure    hypotonia
    squamous cell carcinoma    neurologic diseases    ataxia    esophagitis
    neuronitis    prostatitis    carcinoma


    Export disorders for SLC52A3 gene to outside databases

    Publications
    for SLC52A3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC52A3 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with SLC52A3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and functional characterization of rat riboflavin transporter 2. (PubMed id 19122205)1, 2, 3 Yamamoto S....Yuasa H. (2009)
    2. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2, 3 Deloukas P....Rogers J. (2001)
    3. Brown-Vialetto-Van Laere syndrome, a ponto-bulbar pal sy with deafness, is caused by mutations in c20orf54. (PubMed id 20206331)1, 2 Green P....Josifova D.J. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Four novel C20orf54 mutations identified in Brown-Vial etto-Van Laere syndrome patients. (PubMed id 22718020)1 Dezfouli M.A....Elahi E. (2012)
    7. Decreased blood riboflavin levels are correlated with defective expression of RFT2 gene in gastric cancer. (PubMed id 22791947)1 Eli M....Hasim A. (2012)
    8. Effect of clinical mutations on functionality of the h uman riboflavin transporter-2 (hRFT-2). (PubMed id 22273710)1 Nabokina S.M....Said H.M. (2012)
    9. Brown-Vialetto-Van Laere and Fazio Londe syndrome is associated with a riboflavin transporter defect mimicking mild MADD: a new inborn error of metabolism with potential treatment. (PubMed id 21110228)2 Bosch A.M....Waterham H.R. (2011)
    10. Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells. (PubMed id 21512156)1 Subramanian V.S....Said H.M. (2011)

    External Searches for SLC52A3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing SLC52A3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 113278 HGNC: 16187 AceView: C20orf54 Ensembl:ENSG00000101276 euGenes: HUgn113278
    ECgene: SLC52A3 Kegg: 113278 H-InvDB: SLC52A3

    Other Databases showing SLC52A3 gene

    (According to HUGE)
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    Specialized Databases showing SLC52A3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC52A3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC52A3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC52A3 gene:
    Search GeneIP for patents involving SLC52A3

    GeneCards and IP:
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