Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SLC4A1AP Gene

protein-coding   GIFtS: 50
GCID: GC02P027886

Solute Carrier Family 4 (Anion Exchanger), Member 1, Adaptor...

(Previous names: solute carrier family 4 (anion exchanger), member 1, adapter...)
  See SLC4A1AP-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Solute Carrier Family 4 (Anion Exchanger), Member 1, Adaptor
Protein1 2
     Solute Carrier Family 4 Anion Exchanger Member 1 Adapter Protein2 3
Solute Carrier Family 4 (Anion Exchanger), Member 1, Adapter Protein1 2     HLC-32 3
Lung Cancer Oncogene 31 2     kanadaptin2
Human Lung Cancer Oncogene 3 Protein2 3     Kidney Anion Exchanger Adaptor Protein2
Kidney Anion Exchanger Adapter Protein2 3     

External Ids:    HGNC: 138131   Entrez Gene: 229502   Ensembl: ENSG000001637987   OMIM: 6026555   UniProtKB: Q9BWU03   

Export aliases for SLC4A1AP gene to outside databases

Previous GC identifers: GC02P027807 GC02P027978 GC02P027844 GC02P027861 GC02P027862 GC02P027797 GC02P027739 GC02P027627


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for SLC4A1AP Gene:
SLC4A1AP (solute carrier family 4 (anion exchanger), member 1, adaptor protein) is a protein-coding gene. Diseases associated with SLC4A1AP include lung cancer. An important paralog of this gene is SNIP1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC4A1AP gene promoter:
         TBP   Spz1   Elk-1   STAT5A   PPAR-alpha   TFIID   STAT3   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC4A1AP promoter sequence
   Search Chromatin IP Primers for SLC4A1AP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC4A1AP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p23.3   Ensembl cytogenetic band:  2p23.3   HGNC cytogenetic band: 2p23.3

SLC4A1AP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC4A1AP gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P027886:  view genomic region     (about GC identifiers)

Start:
27,886,338 bp from pter      End:
27,917,847 bp from pter
Size:
31,510 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NADAP_HUMAN, Q9BWU0 (See protein sequence)
Recommended Name: Kanadaptin  
Size: 796 amino acids; 88814 Da
Caution: PubMed:15764369 initially suggested a role in targeting SLC4A1 (kidney anion exchanger 1) to the plasma
membrane; it does not seem to do so as it does not interact with SLC4A1 and has no effect on SLC4A1 trafficking
Sequence caution: Sequence=AAN12269.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for SLC4A1AP:
4H87 (3D)    
Secondary accessions: A6NJ39 Q4KMT1 Q4KMX0 Q7Z5Q9 Q9NVN2

Explore the universe of human proteins at neXtProt for SLC4A1AP: NX_Q9BWU0

Explore proteomics data for SLC4A1AP at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SLC4A1AP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060628.2  
    ENSEMBL proteins: 
     ENSP00000323837   ENSP00000404129  

    SLC4A1AP Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for SLC4A1AP
    OriGene Protein Over-expression Lysate for SLC4A1AP
    OriGene MassSpec for SLC4A1AP
    OriGene Custom Protein Services for SLC4A1AP
    GenScript Custom Purified and Recombinant Proteins Services for SLC4A1AP
    Novus Biologicals SLC4A1AP Proteins
    Novus Biologicals SLC4A1AP Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for SLC4A1AP 

     
    antibodies-online proteins for SLC4A1AP (5 products) 

     
    antibodies-online peptides for SLC4A1AP

    SLC4A1AP Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for SLC4A1AP
    OriGene Custom Antibody Services for SLC4A1AP
    Novus Biologicals SLC4A1AP Antibodies
    Abcam antibodies for SLC4A1AP
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibody for SLC4A1AP
    antibodies-online antibodies for SLC4A1AP (22 products) 

    SLC4A1AP Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SLC4A1AP
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SLC4A1AP
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for SLC4A1AP 
    antibodies-online kits for SLC4A1AP (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR008984 SMAD_FHA_domain
     IPR014720 dsRNA-bd_dom
     IPR000253 FHA_dom

    Graphical View of Domain Structure for InterPro Entry Q9BWU0

    ProtoNet protein and cluster: Q9BWU0

    1 Blocks protein domain: IPB000253 Forkhead-associated (FHA)

    UniProtKB/Swiss-Prot: NADAP_HUMAN, Q9BWU0
    Similarity: Contains 1 FHA domain


    Find genes that share domains with SLC4A1AP           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17553790
         
    Find genes that share ontologies with SLC4A1AP           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Slc4a1ap (no phenotypes)

    Find genes that share phenotypes with SLC4A1AP           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for SLC4A1AP

    miRNA
    Products:
        
    miRTarBase miRNAs that target SLC4A1AP:
    hsa-mir-375 (MIRT019988), hsa-mir-186-5p (MIRT045177), hsa-mir-16-5p (MIRT032022)

    Block miRNA regulation of human, mouse, rat SLC4A1AP using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate SLC4A1AP:
    hsa-miR-616* hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidSLC4A1AP 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SLC4A1AP
    Predesigned siRNA for gene silencing in human, mouse, rat SLC4A1AP

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SLC4A1AP

    Clone
    Products:
         
    OriGene clones in human, mouse for SLC4A1AP (see all 6)
    OriGene ORF clones in mouse, rat for SLC4A1AP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLC4A1AP (NM_018158)
    Sino Biological Human cDNA Clone for SLC4A1AP
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC4A1AP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC4A1AP

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SLC4A1AP
    Browse ESI BIO Cell Lines and PureStem Progenitors for SLC4A1AP 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC4A1AP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    NADAP_HUMAN, Q9BWU0: Nucleus. Cytoplasm. Note=Mainly nuclear. Small amounts are found in the cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with SLC4A1AP           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC4A1AP
    Interactions:

        GeneGlobe Interaction Network for SLC4A1AP

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for SLC4A1AP (Q9BWU01, 3 ENSP000003238374) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ILKQ134181, 3, ENSP000002994214EBI-1999704,EBI-747644 I2D: score=1 STRING: ENSP00000299421
    SLC4A1P027303, ENSP000002624184I2D: score=2 STRING: ENSP00000262418
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    PSMC6P623333, ENSP000004018024I2D: score=1 STRING: ENSP00000401802
    RBL1P287493I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC4A1AP (NADAP)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SLC4A1AP gene: 
    NM_018158.2  

    Unigene Cluster for SLC4A1AP:

    Solute carrier family 4 (anion exchanger), member 1, adaptor protein
    Hs.306000  [show with all ESTs]
    Unigene Representative Sequence: NM_018158
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326019(uc002rlk.4) ENST00000427424 ENST00000492196
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SLC4A1AP using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate SLC4A1AP:
    hsa-miR-616* hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmidSLC4A1AP 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SLC4A1AP
    Predesigned siRNA for gene silencing in human, mouse, rat SLC4A1AP
    Clone
    Products:
         
    OriGene clones in human, mouse for SLC4A1AP (see all 6)
    OriGene ORF clones in mouse, rat for SLC4A1AP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLC4A1AP (NM_018158)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC4A1AP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC4A1AP
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC4A1AP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC4A1AP
      QuantiTect SYBR Green Assays in human, mouse, rat SLC4A1AP
      QuantiFast Probe-based Assays in human, mouse, rat SLC4A1AP

    Additional mRNA sequence: 

    AK001486.1 AK300958.1 AY028435.1 AY117688.1 BC098302.1 BC098358.1 BC099711.1 BC099739.1 
    DQ786283.1 U38432.1 

    12 DOTS entries:

    DT.100675496  DT.100703335  DT.95149029  DT.411112  DT.100826887  DT.92444493  DT.99936021  DT.121010651 
    DT.92444487  DT.95231044  DT.436333  DT.92444491 

    Selected AceView cDNA sequences (see all 203):

    BU616823 AW051810 BF589433 CF528956 AI292134 BP361738 AU146606 CB108688 
    AI224951 AI362266 AY028435 AI027674 AA910253 N26833 AL597506 AI421543 
    CB054194 AI208150 AA748416 BF197202 BX479632 BM015979 AW510652 AW991229 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC4A1AP (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17
    SP1:                                      -                                                                                       
    SP2:        -     -                       -                                                                                       
    SP3:                                                                                                                              
    SP4:                                                                                                                              
    SP5:                                                                                                                              


    ECgene alternative splicing isoforms for SLC4A1AP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SLC4A1AP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCCTATTAA
    SLC4A1AP Expression
    About this image

    SLC4A1AP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC4A1AP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.306000

    UniProtKB/Swiss-Prot: NADAP_HUMAN, Q9BWU0
    Tissue specificity: Ubiquitously expressed

        Custom PCR Arrays for SLC4A1AP
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC4A1AP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC4A1AP
    QuantiTect SYBR Green Assays in human, mouse, rat SLC4A1AP
    QuantiFast Probe-based Assays in human, mouse, rat SLC4A1AP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC4A1AP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for SLC4A1AP gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc4a1ap1 , 5 solute carrier family 4 (anion exchanger), member 1, more1, 5 82.35(n)1
    79.97(a)1
      5 (17.27 cM)5
    205341  NM_009206.21  NP_033232.21 
     315269955 
    chicken
    (Gallus gallus)
    Aves SLC4A1AP1 solute carrier family 4 (anion exchanger), member 1, more 72.59(n)
    72.86(a)
      421420  XM_419473.4  XP_419473.4 
    lizard
    (Anolis carolinensis)
    Reptilia SLC4A1AP6
    solute carrier family 4 (anion exchanger), member ...
    60(a)
    1 ↔ 1
    2(125217249-125239237)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.116012 Transcribed sequence with weak similarity to protein more 73.59(n)    BX717637.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.117622 Transcribed sequence with weak similarity to protein more 78.06(n)    AI878160.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG77061 , 3 anion exchanger adaptor3
    CG77061
    36(a)3
    49.3(n)1
    42.16(a)1
      91C13
    422441  NM_142485.21  NP_650742.21 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK632.23 Coiled coil protein 33(a)   III(9870825-9873999)   --


    ENSEMBL Gene Tree for SLC4A1AP (if available)
    TreeFam Gene Tree for SLC4A1AP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for SLC4A1AP gene
    SNIP12  PPP1R82  

    Find genes that share paralogs with SLC4A1AP           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for SLC4A1AP
    PGOHUM00000245127 PGOHUM00000236000


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SLC4A1AP (see all 582)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1874114621,2
    --27888476(+) TTGTGC/TTATGT 1 -- int10--------
    rs1922073841,2
    --27888505(+) TGGAAC/TTCTAT 1 -- int10--------
    rs1826073541,2
    --27888544(+) TATAGC/GATATT 1 -- int10--------
    rs759578171,2
    C,F--27888729(+) GAAGAT/CAGGAA 1 -- int12Minor allele frequency- C:0.20CSA WA 120
    rs1143245491,2
    C,F--27888758(+) TGCTAA/CGTGCC 1 -- int11Minor allele frequency- C:0.05WA 118
    rs728521921,2
    C,F--27888972(+) AAGAAT/GGTAAA 1 -- int13Minor allele frequency- G:0.06WA 122
    rs1507408281,2
    --27889113(+) GTTGGA/GCAGCA 1 -- int10--------
    rs1390541451,2
    --27889164(+) GTAGAC/GATGGG 1 -- int10--------
    rs778666041,2
    C--27889222(+) CCACCA/CCCCAC 1 -- int11Minor allele frequency- C:0.00NA 2
    rs134262061,2
    C--27889229(+) ccaccA/Cccccc 1 -- int1 trp30--------

    HapMap Linkage Disequilibrium report for SLC4A1AP (27886338 - 27917847 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SLC4A1AP:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2660490CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing SLC4A1AP
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC4A1AP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 602655    OMIM disorders: --

    1 disease for SLC4A1AP:    
    About MalaCards
    lung cancer


    Find genes that share disorders with SLC4A1AP           About GenesLikeMe

    Genetic Association Database (GAD): SLC4A1AP

    Export disorders for SLC4A1AP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SLC4A1AP gene, integrated from 10 sources (see all 36):
    (articles sorted by number of sources associating them with SLC4A1AP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human kanadaptin and kidney anion exchanger 1 (kAE1) do not interact in transfected HEK 293 cells. (PubMed id 15764369)1, 2, 9 Kittanakom S.... Reithmeier R.A.F. (Mol. Membr. Biol. 2004)
    2. Kanadaptin is a protein that interacts with the kidney but not the erythroid form of band 3. (PubMed id 9422766)1, 3, 9 Chen J....Al-Awqati Q. (J. Biol. Chem. 1998)
    3. A comprehensive genetic association study of Alzheimer disease in African Americans. (PubMed id 22159054)1, 4 Logue M.W....Farrer L.A. (Arch. Neurol. 2011)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. Genetic variants associated with breast size also influence breast cancer risk. (PubMed id 22747683)1 Eriksson N....Tung J.Y. (BMC Med. Genet. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 22950 HGNC: 13813 AceView: SLC4A1AP Ensembl:ENSG00000163798 euGenes: HUgn22950
    ECgene: SLC4A1AP H-InvDB: SLC4A1AP

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SLC4A1AP Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Band_3

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SLC4A1AP gene:
    Search GeneIP for patents involving SLC4A1AP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for SLC4A1AP   OriGene RNAi products in human, mouse, rat for SLC4A1AP  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for SLC4A1AP  
     OriGene MassSpec for SLC4A1AP   OriGene clones in human, mouse for SLC4A1AP  
     OriGene qSTAR qPCR primer pairs in human, mouse for SLC4A1AP   OriGene Purified Protein for SLC4A1AP  
     OriGene ORF clones in mouse, rat for SLC4A1AP   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SLC4A1AP   OriGene Custom Protein Services for SLC4A1AP  

     
     
     Block miRNA regulation of human, mouse, rat SLC4A1AP using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SLC4A1AP
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC4A1AP Predesigned siRNA for gene silencing in human, mouse, rat SLC4A1AP
     QuantiFast Probe-based Assays in human, mouse, rat SLC4A1AP QuantiTect SYBR Green Assays in human, mouse, rat SLC4A1AP
     Custom PCR Arrays for SLC4A1AP Search Chromatin IP Primers for SLC4A1AP
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC4A1AP  GeneGlobe Interaction Network for SLC4A1AP
     Regulatory tfbs in SLC4A1AP promoter
     GenScript Custom Purified and Recombinant Proteins Services for SLC4A1AP GenScript cDNA clones with any tag delivered in your preferred vector for SLC4A1AP
     GenScript Custom Assay Services for SLC4A1AP GenScript Custom overexpressing Cell Line Services for SLC4A1AP
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SLC4A1AP (NADAP)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for SLC4A1AP
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SLC4A1AP antibodies
     SLC4A1AP proteins
     SLC4A1AP lysates
     Antibodies for SLC4A1AP
     See all of Abcam's Antibodies, Kits and Proteins for SLC4A1AP
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for SLC4A1AP
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC4A1AP
     SwitchGear 3'UTR luciferase reporter plasmids for SLC4A1AP
     SwitchGear Promoter luciferase reporter plasmids for SLC4A1AP
     ThermoFisher Antibody for SLC4A1AP
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC4A1AP
     Browse compounds at ApexBio
     Search Addgene for plasmids for SLC4A1AP
      Search eBioscience for proteins for SLC4A1AP
      Search eBioscience for elisas for SLC4A1AP
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for SLC4A1AP
     antibodies-online antibodies for SLC4A1AP (22 products)
     antibodies-online kits for SLC4A1AP (2 products)
     antibodies-online peptides for SLC4A1AP
     antibodies-online proteins for SLC4A1AP (5 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SLC4A1AP gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4