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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SLC4A10 Gene

protein-coding GIFtS: 59
GCID: GC02P162281

solute carrier family 4, sodium bicarbonate transporter,...

(Previous names: solute carrier family 4, sodium bicarbonate transporter-like,...)

Explore 9 diseases affiliated with
SLC4A10 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Solute Carrier Family 4, Sodium Bicarbonate Transporter, Member 10¹ ²		Sodium-Driven Chloride Bicarbonate Exchanger²
NCBE¹ ² ³		Solute Carrier Family 4, Sodium Bicarbonate Cotransporter-Like, Member 10²
NBCn2¹ ²		Solute Carrier Family 4 Member 10³
Solute Carrier Family 4, Sodium Bicarbonate Transporter-Like, Member 10¹

External Ids:	HGNC: 13811¹	Entrez Gene: 57282²	Ensembl: ENSG00000144290⁷	OMIM: 605556⁵	UniProtKB: Q6U841³

Export aliases for SLC4A10 gene to outside databases

Previous GC identifers: GC02P160534 GC02P161009 GC02P162444 GC02P162683 GC02P162306 GC02P162189 GC02P154363

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC4A10:

This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular

pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular

fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger

(NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride

ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of

transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct

isoforms.(provided by RefSeq, May 2010)

UniProtKB/Swiss-Prot: S4A10_HUMAN, Q6U841

Function: Electrogenic sodium/bicarbonate cotransporter in exchange for intracellular chloride. Plays an important role

in regulating intracellular pH (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_005403.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SLC4A10 gene promoter:
AML1a AP-4 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 Evi-1 AREB6 POU2F1 HSF2 POU2F1a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC4A10 promoter sequence

Search SABiosciences Chromatin IP Primers for SLC4A10

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC4A10

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.2 Ensembl cytogenetic band: 2q24.2 HGNC cytogenetic band: 2q24.2

SLC4A10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC4A10 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P162281: view genomic region (about GC identifiers)

Start:	162,280,843 bp from pter	End:	162,841,792 bp from pter
Size:	560,950 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: S4A10_HUMAN, Q6U841 (See protein sequence)

Recommended Name: Sodium-driven chloride bicarbonate exchanger

Size: 1118 amino acids; 125946 Da

Subcellular location: Cell membrane; Multi-pass membrane protein. Note=Localizes to the basolateral membrane (By

similarity)

Secondary accessions: B7Z1R0 B7ZLC5 B9EG69 F8W675 Q4ZFX6 Q8TCP2 Q9HCQ6

Alternative splicing: 3 isoforms: Q6U841-1 Q6U841-2 Q6U841-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC4A10: NX_Q6U841

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6U841

SLC4A10 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001171486.1 NP_001171487.1 NP_071341.2

ENSEMBL proteins:

ENSP00000395797 ENSP00000272716 ENSP00000412871 ENSP00000393066 ENSP00000404486

ENSP00000389180 ENSP00000387716 ENSP00000437527 ENSP00000364664

Reactome Protein details: Q6U841
Human Recombinant Protein Products:

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	Uscn Proteins for SLC4A10

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	--
GO:0016021	integral to membrane	NAS	10993873
GO:0016323	basolateral plasma membrane	IEA	--

SLC4A10 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SLC4A10 for domains About GeneDecksing

5 InterPro domains/families:

IPR011531 HCO3_transpt_C

IPR003020 HCO3_transpt_euk

IPR016152 PTrfase/Anion_transptr

IPR003024 Na/HCO3_transpt

IPR013769 HCO3_transpt_cyt

Graphical View of Domain Structure for InterPro Entry Q6U841

ProtoNet protein and cluster: Q6U841

2 Blocks protein families:

IPB003024 Na+/HCO3- co-transporter signature

IPB013769 HCO3- transporter

UniProtKB/Swiss-Prot: S4A10_HUMAN, Q6U841

Similarity: Belongs to the anion exchanger (TC 2.A.31) family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: S4A10_HUMAN, Q6U841

Function: Electrogenic sodium/bicarbonate cotransporter in exchange for intracellular chloride. Plays an important role

in regulating intracellular pH (By similarity)

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		hsa-miR-376b hsa-miR-25 hsa-miR-4325 hsa-miR-330-3p hsa-miR-92b hsa-miR-181b hsa-miR-505 hsa-miR-92a

		SwitchGear 3'UTR luciferase reporter plasmid: SLC4A10 3' UTR sequence

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC4A10

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005452	inorganic anion exchanger activity	IEA	--
GO:0015293	symporter activity	IEA	--
GO:0015301	anion:anion antiporter activity	--	--

SLC4A10 for ontologies           About GeneDecksing

Animal Models:
     Mouse knock-out Slc4a10^tm1.1Cahb for SLC4A10
     5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Slc4a10):

behavior/neurological

growth/size

homeostasis/metabolism

mortality/aging

nervous system

SLC4A10 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

SLC-mediated transmembrane transport

SLC-mediated transmembrane transport

1.00

Transmembrane transport of small molecules

0.50

Bicarbonate transporters

Bicarbonate transporters

1.00

Amino acid and oligopeptide SLC transporters

Transport of inorganic cations/anions and amino acids/oligopeptides

0.52

Pathway sources
See GeneCards unified pathways
Show all pathways

4 Reactome Pathways for SLC4A10

	Bicarbonate transporters
	SLC-mediated transmembrane transport
	Transmembrane transport of small molecules
	Transport of inorganic cations/anions and amino acids/oligopeptides

SLC4A10 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SLC4A10

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

4 Interacting proteins for SLC4A10 (Q6U841³ ENSP00000395797⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CBFB	Q13951³	I2D: score=1
FOS	P01100³	I2D: score=1
YWHAB	P31946³	I2D: score=1
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	TAS	--
GO:0006814	sodium ion transport	IEA	--
GO:0006821	chloride transport	NAS	10993873
GO:0006885	regulation of pH	IEA	--
GO:0015701	bicarbonate transport	TAS	--

SLC4A10 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SLC4A10

3 HMDB Compounds for SLC4A10 About this table

Compound	Synonyms	CAS #	PubMed Ids
Chlorine	Cl2 (see all 13)	16887-00-6	--
Hydrogen carbonate	Bicarbonate (see all 19)	71-52-3	--
Sodium	Sodium (see all 2)	7440-23-5	--

1 DrugBank Compound for SLC4A10 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Sodium bicarbonate	Bicarbonate of soda (see all 6)	144-55-8	transporter	substrate	15014910 17071329 12847417 12027220

Search CenterWatch for drugs/clinical trials and news about SLC4A10 / S4A10

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SLC4A10 gene (3 alternative transcripts):

NM_001178015.1 NM_001178016.1 NM_022058.3

Unigene Cluster for SLC4A10:

Solute carrier family 4, sodium bicarbonate transporter, member 10

Hs.333958 [show with all ESTs]

Unigene Representative Sequence: NM_001178016

13 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000482861 ENST00000415876 ENST00000493021(uc010fpa.1) ENST00000461456

ENST00000272716 ENST00000449513 ENST00000446997 ENST00000481721 ENST00000421911

ENST00000446228 ENST00000415711 ENST00000535165(uc010zcr.1) ENST00000375514(uc002ubx.4 uc010zcs.2 uc002uby.4)

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		hsa-miR-376b hsa-miR-25 hsa-miR-4325 hsa-miR-330-3p hsa-miR-92b hsa-miR-181b hsa-miR-505 hsa-miR-92a

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Additional cDNA sequence:

AK293793.1 AK294767.1 AK308529.1 AK309839.1 AL713680.1 AL832525.1 AY376402.1 BC036415.2

BC038298.1 BC051190.1 BC136269.1 BC143714.1

5 DOTS entries:

DT.100730828 DT.102842626 DT.102842625 DT.40293654 DT.100674496

24/102 AceView cDNA sequences (see all 102):

BM664443 CD631089 AY376402 BC036415 AL713680 CD631074 BM696161 BX951604

AL832525 BQ067691 BX952927 BE702100 NM_022058 CD102396 CD631067 CD631069

CD631063 BX955341 BC051190 CA775920 CD631075 BC038298 CD631070 AU185739

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for SLC4A10 About this scheme

ExUns:	1	^	2a	·	2b	^	3	^	4	^	5a	·	5b
SP1:									-
SP2:

ECgene alternative splicing isoforms for SLC4A10

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SLC4A10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCACCTATT

About this image

SLC4A10 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Choroid Plexus

Mature Choroid Plexus Cells

Selective marker (cell-identifying gene)

Choroid Plexus

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SLC4A10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC4A10

SOURCE GeneReport for Unigene cluster: Hs.333958

SABiosciences Custom PCR Arrays for SLC4A10

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC4A10

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC4A10 gene from 8/23 species (see all 23) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SLC4A10¹	solute carrier family 4, sodium bicarbonate transporter, more	82.51(n) 92.4(a)		424188 XM_003641613.1 XP_003641661.1
lizard (Anolis carolinensis)	Reptilia	SLC4A10⁶	--	89(a)	1 ↔ 1	GL343359.1(728877-797414)
African clawed frog (Xenopus laevis)	Amphibia	Xl.19338²	Xenopus laevis transcribed sequence with moderate similarity more	76(n)		BQ384734.1
zebrafish (Danio rerio)	Actinopterygii	slc4a10b⁶ CR450841.1⁶	--	81(a) 80(a)	1 ↔ many 1 ↔ many	9(52636193-52713526) 11(10749677-10803733)
fruit fly (Drosophila melanogaster)	Insecta	Ndae1³	sodium:bicarbonate cotransporter	53(a)		27E6 --
worm (Caenorhabditis elegans)	Secernentea	F52B5.1³	anion exchange protein	47(a) (best of 2)		I(8305353-8315575) --
thale cress (Arabidopsis thaliana)	eudicotyledons	BOR5⁶ AT4G32510⁶ (see all 7)	putative boron transporter 7 (see all 7)	20(a) 20(a) (see all 7)	possible ortholog possible ortholog (see all 7)	1(28108474-28111534) 4(15685903-15688811)
rice (Oryza sativa)	Liliopsida	BOR4⁶ BOR3⁶ (see all 3)	boron transporter protein, putative, expressed (see all 3)	20(a) 20(a) (see all 3)	possible ortholog possible ortholog (see all 3)	5(4600956-4607390) 1(3877069-3899085)

ENSEMBL Gene Tree for SLC4A10 (if available)
TreeFam Gene Tree for SLC4A10 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SLC4A10 gene

SLC4A4² SLC4A7² SLC4A1² SLC4A11² SLC4A5² SLC4A8² SLC4A2² SLC4A3²

SLC4A9²

12 SIMAP similar genes for SLC4A10 using alignment to 8 protein entries: S4A10_HUMAN (see all proteins):

DKFZp781H1314 SLC4A8 SLC4A7 SLC4A4 NBC SLC4A5

SLC4A9 SLC4A2 SLC4A1 SLC4A3 AE AE1

SLC4A10 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs116094561^1,2	C,F,	--	154362306(+)	`TTAGTT/GATATT`	3	--	us2k¹		1		WA	118
rs72873621^1,2	C,	--	154362614(+)	`ATGTTC/TTCTTA`	3	--	us2k¹		0	--	--	--	--
rs114789088^1,2	C,F,	--	154363087(+)	`GCTTGG/AGCTAT`	3	--	us2k¹		1		WA	118
rs11682658^1,2	C,H	--	154363413(+)	`CCTAGT/CAAACC`	3	--	us2k¹		5		NS EA NA	420
rs17225644^1,2	C,F,	--	154364593(+)	`CTCTGG/TGTTCT`	3	--	int¹		6		NA	266
rs79019457^1,2	F,	--	154366253(+)	`AGACGA/GCTTTG`	3	--	int¹		1		WA	118
rs74778302^1,2		--	154366659(+)	`GTGGGA/GGGTGG`	3	--	int¹		0	--	--	--	--
rs73007045^1,2	C,F,	--	154367087(+)	`TAAGTG/ATATAG`	3	--	int¹		3		WA CSA	122
rs73971334^1,2	C,	--	154367236(+)	`CACCCC/TATATA`	3	--	int¹		1		WA	2
rs56721699^1,2		--	154367561(+)	`AATATA/GTAACT`	3	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SLC4A10 (162280843 - 162530843 bp, first 250kb of SLC4A10)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for SLC4A10
2 CNVs: 90105 98041
2 Indels: 58929 26482
Human Gene Mutation Database (HGMD): SLC4A10

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SLC4A10 for disorders           About GeneDecksing

OMIM gene information: 605556    OMIM disorders: --

9 diseases for SLC4A10:    About MalaCards

open-angle glaucoma psychogenic depressive psychosis primary open angle glaucoma complex partial epilepsy

choroiditis glaucoma neuronitis hepatitis c

hepatitis

2 diseases from the University of Copenhagen DISEASES database for SLC4A10:

Complex partial epilepsy Endogenous depression

Human Genome Epidemiology (HuGE) Navigator: SLC4A10 (3 documents)

Export disorders for SLC4A10 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SLC4A10 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with SLC4A10)

Utopia: connect your pdf to the dynamic
world of online information

Characterization of human SLC4A10 as an electroneutral Na/HCO3 cotransporter (NBCn2) with Cl- self-exchange activity. (PubMed id 18319254)^{1, 3} Parker M.D....Boron W.F. (2008)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)^{1, 2} Hillier L.W....Wilson R.K. (2005)
The Na+-driven Cl-/HCO3- exchanger. Cloning, tissue distribution, and functional characterization. (PubMed id 10993873)^{1, 2} Wang C.-Z.... Seino S. (2000)
Assignment of the human solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 gene (SLC4A10) to 2q23-->q24 by in situ hybridization and radiation hybrid mapping. (PubMed id 10965143)^{1, 9} Yano H....Seino S. (2000)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Large-scale candidate gene analysis of spontaneous cl earance of hepatitis C virus. (PubMed id 20331378)¹ Mosbruger T.L....Thio C.L. (2010)
AQP1 and SLC4A10 as candidate genes for primary open- angle glaucoma. (PubMed id 20101282)¹ Liu W....Allingham R.R. (2010)
Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability. (PubMed id 18165320)¹ Jacobs S....Hubner C.A. (2008)
Disruption of sodium bicarbonate transporter SLC4A10 in a patient with complex partial epilepsy and mental retardation. (PubMed id 18413482)¹ Gurnett C.A....Bowcock A. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57282	HGNC: 13811	AceView: SLC4A10	Ensembl:ENSG00000144290	euGenes: HUgn57282
ECgene: SLC4A10	H-InvDB: SLC4A10

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SLC4A10	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SLC4A10 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SLC4A10 gene:
Search GeneIP for patents involving SLC4A10

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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