SLC47A2 Gene
protein-coding GIFtS: 52
GCID: GC17M019582
|
|
solute carrier family 47, member 2
| |
Aliases for SLC47A2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Solute Carrier Family 47, Member 21 2 | | MATE2K2 5 | | MATE21 2 3 5 | | MATE2-B2 | | MATE2-K1 2 | | H+/Organic Cation Antiporter2 | | Kidney-Specific H(+)/Organic Cation Antiporter2 3 | | Multidrug And Toxin Extrusion 22 | | MATE-22 3 | | Multidrug And Toxin Extrusion Protein 22 | | HMATE-21 | | Solute Carrier Family 47 Member 23 | | FLJ311961 5 | | |
Export aliases for SLC47A2 gene to outside databasesPrevious GC identifers: GC17M019524 GC17M018960 |
Summaries for SLC47A2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for SLC47A2: This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, bothendogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE(multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of theMATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encodingdifferent isoforms have been identified for this gene. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: S47A2_HUMAN, Q86VL8Function: Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine,N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, andganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes Gene Wiki entry for SLC47A2
|
Genomic Views for SLC47A2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SLC47A2 gene promoter: STAT5B STAT1 STAT4 STAT6 STAT1beta STAT5A STAT1alpha C/EBPalpha STAT2 STAT3 Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC47A2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC47A2 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p11.2 Ensembl cytogenetic band: 17p11.2 HGNC cytogenetic band: 17p11.2SLC47A2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M019582: view genomic region
(about GC identifiers)
Start:
|
19,581,601 bp from pter |
End:
|
19,622,292 bp from pter |
Size:
|
40,692 bases |
Orientation:
|
minus strand |
|
Proteins for SLC47A2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: S47A2_HUMAN, Q86VL8 (See
protein sequence)Recommended Name: Multidrug and toxin extrusion protein 2 Size: 602 amino acids; 65085 Da
Subcellular location: Cell membrane; Multi-pass membrane protein (Potential). Note=Localized at the brush bordermembranes of the proximal tubules
Secondary accessions: A0JBX9 A0P8Z7 Q63HJ9 Q8IV44 Q96NA1Alternative splicing: 6 isoforms: Q86VL8-1 Q86VL8-2 Q86VL8-3 Q86VL8-4 Q86VL8-5 Q86VL8-6 (Inactive. Note)Explore the universe of human proteins at neXtProt for SLC47A2: NX_Q86VL8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86VL8 SLC47A2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001093116.1 NP_001243592.1 NP_690872.2 ENSEMBL proteins: ENSP00000326671 ENSP00000338084 ENSP00000458694 ENSP00000391848 Reactome Protein details: Q86VL8 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SLC47A2 for ontologies About GeneDecksing
SLC47A2 Antibody Products: Assay Products for SLC47A2: |
Protein
Domains / Families for SLC47A2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC47A2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q86VL8ProtoNet protein and cluster: Q86VL8 1 Blocks protein family: IPB002528 Multi antimicrobial extrusion protein MatE
UniProtKB/Swiss-Prot: S47A2_HUMAN, Q86VL8Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family |
Function for SLC47A2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: S47A2_HUMAN, Q86VL8Function: Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine,N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, andganciclovir. Responsible for the secretion of cationic drugs across the brush border membranesBiophysicochemical properties: Kinetic parameters: KM=0.76 mM for TEA; KM=0.11 mM for MPP; KM=0.12 mM for cimetidine;KM=1.98 mM for metformin; KM=4.2 mM for guanidine; KM=1.58 mM for procainamide; KM=0.06 mM for topotecan; KM=0.85 mMfor estrone sulfate; KM=4.32 mM for acyclovir; KM=4.28 mM for ganciclovir; Vmax=0.88 nmol/min/mg enzyme toward TEA;Vmax=0.575 nmol/min/mg enzyme toward MPP; Vmax=0.115 nmol/min/mg enzyme toward cimetidine; Vmax=0.845 nmol/min/mgenzyme toward metformin; Vmax=0.58 nmol/min/mg enzyme toward guanidine; Vmax=3.385 nmol/min/mg enzyme towardprocainamide; Vmax=0.13 nmol/min/mg enzyme toward topotecan; Vmax=0.425 nmol/min/mg enzyme toward estrone sulfate;Vmax=0.945 nmol/min/mg enzyme toward acyclovir; Vmax=0.805 nmol/min/mg enzyme toward ganciclovir; pH dependence:Optimum pH is 9.0. Active from pH 6 to 9;
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC47A2 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC47A2 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SLC47A2 (NM_152908) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC47A2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC47A2  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC47A2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0015238 | drug transmembrane transporter activity |
IEA | -- | | GO:0015297 | antiporter activity |
IEA | -- |
SLC47A2 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for SLC47A2:
|
Pathways & Interactions for SLC47A2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | SLC-mediated transmembrane transport | | | 2 | Bile salt and organic anion SLC transporters | |
Pathway sources See GeneCards unified pathways Show all pathways
4
Reactome Pathways for SLC47A2
SLC47A2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC47A2
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0055085 | transmembrane transport |
TAS | -- |
SLC47A2 for ontologies About GeneDecksing
|
Drugs & Compounds for SLC47A2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for SLC47A2 Search CenterWatch for drugs/clinical trials and news about SLC47A2 / S47A2 
|
Transcripts for SLC47A2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SLC47A2 gene (3 alternative transcripts): NM_001099646.1 NM_001256663.1 NM_152908.3 Unigene Cluster for SLC47A2: Solute carrier family 47, member 2 Hs.126830 [show with all ESTs]Unigene Representative Sequence: BX64886110 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000325411 ENST00000467609 ENST00000463318(uc002gwi.3) ENST00000350657(uc002gwe.4 uc002gwg.4 uc002gwf.4 uc002gwh.4 uc010cqs.1) ENST00000574239 ENST00000433844 ENST00000574220(uc010cqt.1) ENST00000467379 ENST00000483510 ENST00000456947
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC47A2 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC47A2 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): SLC47A2 (NM_152908) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC47A2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC47A2  |
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC47A2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SLC47A2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC47A2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC47A2 |
Additional cDNA sequence: AB250364.1 AB250701.1 AK055758.1 AK307647.1 AK310218.1 BC035288.1 BC050578.1 BC062614.1 BX648861.1 10 DOTS entries: DT.97839140 DT.99936361 DT.97815326 DT.100017478 DT.101980033 DT.120981829 DT.40126658 DT.100647363 DT.75133123 DT.91860425 24/52 AceView cDNA sequences (see all 52): AA931466 AI861851 BC035288 AW006868 AK123589 BC062614 AI074484 BF432333 AI795956 AI245393 AI640517 AW614840 BC050578 NM_152908 BM924669 BM930596 AI240993 BI760930 BM750139 BI762150 AL699675 AK055758 AW271387 BM557728 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SLC47A2 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SLC47A2
|
Expression for SLC47A2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC47A2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
About this image See SLC47A2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SLC47A2
SOURCE GeneReport for Unigene cluster: Hs.126830 UniProtKB/Swiss-Prot: S47A2_HUMAN, Q86VL8Tissue specificity: Isoform 3 is predominantly expressed in kidney. Isoform 6 is expressed in brain SABiosciences Custom PCR Arrays for SLC47A2
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC47A2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SLC47A2 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC47A2 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC47A2 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC47A2 |
Orthologs for SLC47A2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for SLC47A2 gene from 7/24 species (see all 24) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
SLC47A26 |
Uncharacterized protein |
60(a) |
1 ↔ 1 |
19(6798886-6804788) |
lizard (Anolis carolinensis) |
Reptilia |
SLC47A26 |
-- |
44(a) |
1 ↔ 1 |
AAWZ02039426(443-4021) |
zebrafish (Danio rerio) |
Actinopterygii |
slc47a11 |
solute carrier family 47, member 1 |
54.39(n) 46.36(a) |
  |
541497 NM_001014310.2 NP_001014332.2 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
YDR338C1 |
hypothetical protein |
40.02(n) 30.07(a) |
  |
851938 NP_010625.1 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT4G230301 |
mate efflux domain-containing protein |
44.14(n) 33.56(a) |
  |
828402 NM_118432.1 NP_194034.1 |
rice (Oryza sativa) |
Liliopsida |
Os04g05716001 |
hypothetical protein |
47.35(n) 31.14(a) |
  |
4336717 NM_001060141.2 NP_001053606.2 |
E. coli (Escherichia coli) |
Gamma proteobacteria |
mdtK6 |
multidrug efflux system transporter |
19(a) |
1 → many |
Chromosome(1741481-1742854) |
Species with no ortholog for SLC47A2
ENSEMBL Gene Tree for SLC47A2 (if available) TreeFam Gene Tree for SLC47A2 (if available)  |
Paralogs for SLC47A2 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for SLC47A2 gene
- SLC47A12
1 SIMAP similar gene for SLC47A2 using alignment to 2 protein entries: S47A2_HUMAN (see all proteins):SLC47A1
SLC47A2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for SLC47A2 PGOHUM00000245557
|
Genomic Variants for SLC47A2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC47A2 (19581601 - 19622292 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SLC47A2: -- Human Gene Mutation Database (HGMD): SLC47A2
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC47A2 |
|
Disorders
/ Diseases for SLC47A2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SLC47A2 for disorders About GeneDecksing
OMIM gene information: 609833
OMIM disorders: --
2 diseases for SLC47A2: About MalaCardsdyslexia pneumonia 1 disease from the University of Copenhagen DISEASES database for SLC47A2:Dyslexia Human Genome Epidemiology (HuGE) Navigator: SLC47A2 (3 documents) Export disorders for SLC47A2 gene to outside databases
|
Publications for SLC47A2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC47A2 gene, integrated from 9 sources (see all 18): (articles sorted by number of sources associating them with SLC47A2) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification and functional characterization of a new human kidney- specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2. (PubMed id 16807400)1, 2, 3 Masuda S.... Inui K. (2006)
- The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations. (PubMed id 16996621)1, 2, 3 Omote H....Moriyama Y. (2006)
- Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters. (PubMed id 17509534)1, 2 Tanihara Y.... Inui K. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Exploring the transcriptome of ciliated cells using in silico dissection of human tissues. (PubMed id 22558177)1 Ivliev A.E....Sergeeva M.G. (2012)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Evaluation of 4',6-diamidino-2-phenylindole as a fluo rescent probe substrate for rapid assays of the functionality of human multidru g and toxin extrusion proteins. (PubMed id 20047987)1 Yasujima T....Yuasa H. (2010)
- Heterozygous variants of multidrug and toxin extrusio ns (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients. (PubMed id 20016398)1 Toyama K....Inui K. (2010)
- Functional characteristics of two human MATE transpor ters: kinetics of cimetidine transport and profiles of inhibition by various co mpounds. (PubMed id 20067714)1 Ohta K.Y....Yuasa H. (2009)
- Identification of multidrug and toxin extrusion (MATE 1 and MATE2-K) variants with complete loss of transport activity. (PubMed id 19158817)1 Kajiwara M....Inui K. (2009)
|
External Searches for SLC47A2 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SLC47A2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC47A2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC47A2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SLC47A2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SLC47A2 gene: Search GeneIP for patents involving SLC47A2
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SLC47A2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC47A2 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC47A2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC47A2 | | OriGene Protein Over-expression Lysate for SLC47A2 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SLC47A2 | | OriGene 3'-UTR Clone for SLC47A2 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC47A2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC47A2 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SLC47A2 | | OriGene Custom Protein Services for SLC47A2 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC47A2 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC47A2 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC47A2 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC47A2 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC47A2 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC47A2 |
| |
 |  |  |  | |
| | | Search Tocris compounds for SLC47A2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | SLC47A2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC47A2 |
|  |  |  | | | ThermoFisher Antibodies for SLC47A2 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC47A2 |
|
|
|
|