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SLC45A2 Gene

protein-coding   GIFtS: 53
GCID: GC05M033981

Solute Carrier Family 45, Member 2

(Previous name: membrane associated transporter)
(Previous symbol: MATP)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 45, Member 21 2     OCA42 5
MATP1 2 3 5     SHEP52 5
AIM12 3 5     1A12
Membrane Associated Transporter1 2     Membrane-Associated Transporter Protein2
Melanoma Antigen AIM12 3     underwhite2
Protein AIM-12 3     Solute Carrier Family 45 Member 23

External Ids:    HGNC: 164721   Entrez Gene: 511512   Ensembl: ENSG000001641757   OMIM: 6062025   UniProtKB: Q9UMX93   

Export aliases for SLC45A2 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC45A2 Gene:
This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high
percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and
polymorphisms in this gene are associated with variations in skin and hair color. Multiple transcript variants
encoding different isoforms have been found for this gene. (provided by RefSeq, Mar 2009)

GeneCards Summary for SLC45A2 Gene:
SLC45A2 (solute carrier family 45, member 2) is a protein-coding gene. Diseases associated with SLC45A2 include oculocutaneous albinism type 4, and melanoma. An important paralog of this gene is SLC45A4.

UniProtKB/Swiss-Prot: S45A2_HUMAN, Q9UMX9
Function: Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By
similarity)

Gene Wiki entry for SLC45A2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NT_006576.17  NC_018916.2  NT_187551.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC45A2 gene promoter:
         Sp1   SREBP-1c   CBF-C   SREBP-1b   SREBP-1a   CBF-B   CBF-A   CP1A   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC45A2 promoter sequence
   Search Chromatin IP Primers for SLC45A2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC45A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p13.2   Ensembl cytogenetic band:  5p13.2   HGNC cytogenetic band: 5p13.3

SLC45A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC45A2 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M033981:  view genomic region     (about GC identifiers)

Start:
33,944,721 bp from pter      End:
33,984,835 bp from pter
Size:
40,115 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: S45A2_HUMAN, Q9UMX9 (See protein sequence)
Recommended Name: Membrane-associated transporter protein  
Size: 530 amino acids; 58268 Da
Sequence caution: Sequence=AAH03597.1; Type=Frameshift; Positions=188;
Secondary accessions: Q6P2P0 Q9BTM3
Alternative splicing: 4 isoforms:  Q9UMX9-1   Q9UMX9-2   Q9UMX9-3   Q9UMX9-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC45A2: NX_Q9UMX9

Explore proteomics data for SLC45A2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn356
  • Modification sites at PhosphoSitePlus

  • See SLC45A2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001012527.1  NP_057264.3  

    ENSEMBL proteins: 
     ENSP00000296589   ENSP00000371534   ENSP00000424010   ENSP00000421100   ENSP00000341014  
     ENSP00000340444  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: SLC45A2
    SLC45 orphans

    1 InterPro protein domain:
     IPR016196 MFS_dom_general_subst_transpt

    Graphical View of Domain Structure for InterPro Entry Q9UMX9

    ProtoNet protein and cluster: Q9UMX9

    UniProtKB/Swiss-Prot: S45A2_HUMAN, Q9UMX9
    Similarity: Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family


    SLC45A2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S45A2_HUMAN, Q9UMX9
    Function: Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By
    similarity)

    Phenotypes:
         7 MGI mutant phenotypes (inferred from 18 alleles(MGI details for Slc45a2):

     behavior/neurological  growth/size/body  homeostasis/metabolism  integument  pigmentation 
     reproductive system  vision/eye 

    SLC45A2 for phenotypes           About GeneDecksing

    Animal Models:
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    miRTarBase miRNAs that target SLC45A2:
    hsa-mir-21-5p (MIRT030963), hsa-mir-25-3p (MIRT050329), hsa-mir-98-5p (MIRT027715), hsa-mir-124-3p (MIRT022895)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S45A2_HUMAN, Q9UMX9: Melanosome membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular2
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--
    GO:0033162melanosome membrane IEA--

    SLC45A2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC45A2
    Interactions:

        Search GeneGlobe Interaction Network for SLC45A2

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007601visual perception IEA--
    GO:0042438melanin biosynthetic process IEA--
    GO:0048066developmental pigmentation IEA--
    GO:0050896response to stimulus IEA--
    GO:0055085transmembrane transport ----

    SLC45A2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC45A2 (S45A2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC45A2 gene (2 alternative transcripts): 
    NM_001012509.2  NM_016180.3  

    Unigene Cluster for SLC45A2:

    Solute carrier family 45, member 2
    Hs.278962  [show with all ESTs]
    Unigene Representative Sequence: NM_001012509
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296589(uc003jid.3) ENST00000382102(uc003jie.3) ENST00000510600
    ENST00000509381(uc003jif.4) ENST00000505056 ENST00000342059 ENST00000345083(uc011coe.1)

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    Additional mRNA sequence: 

    AF172849.1 BC003597.1 BC064405.1 

    5 DOTS entries:

    DT.100009858  DT.97810206  DT.92418433  DT.92418432  DT.75182601 

    Selected AceView cDNA sequences (see all 70):

    BU179292 BQ677464 BU838274 BU184927 BQ677908 BU194436 BU839037 BQ421552 
    BQ894058 BQ680375 N27920 BQ676555 BQ679448 BQ675907 BU179462 BQ676017 
    BQ677454 BQ877593 BQ682447 BQ678442 BQ883505 BQ679269 BQ677110 BU168577 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SLC45A2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7
    SP1:                                            -                     
    SP2:                    -     -                                       
    SP3:                                                                  
    SP4:              -                                                   
    SP5:                                                                  


    ECgene alternative splicing isoforms for SLC45A2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC45A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGTTGGGGG
    SLC45A2 Expression
    About this image

    SLC45A2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC45A2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.278962

    UniProtKB/Swiss-Prot: S45A2_HUMAN, Q9UMX9
    Tissue specificity: Expressed in most melanoma cell lines and melanocytes

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SLC45A2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc45a21 , 5 solute carrier family 45, member 21, 5 83.18(n)1
    82.42(a)1
      15 (5.40 cM)5
    222931  NM_053077.31  NP_444307.11 
     110007215 
    chicken
    (Gallus gallus)
    Aves SLC45A21 solute carrier family 45, member 2 69.38(n)
    69.33(a)
      431665  NM_001083364.1  NP_001076833.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.56002 Transcribed sequence with moderate similarity to protein spQ9UMX9 (H.sapiens) MATP_HUMAN Membrane-associated transporter protein (AIM-1 protein) (Melanoma antigen AIM1) less 77.84(n)    BX712162.1 
    zebrafish
    (Danio rerio)
    Actinopterygii slc45a21 solute carrier family 45, member 2 64.11(n)
    65.86(a)
      558311  NM_001110377.1  NP_001103847.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG410876
    --
    29(a)
    1 → many
    U(2089457-2090079)


    ENSEMBL Gene Tree for SLC45A2 (if available)
    TreeFam Gene Tree for SLC45A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC45A2 gene
    SLC45A42  SLC45A12  SLC45A32  
    1 SIMAP similar gene for SLC45A2 using alignment to 4 protein entries:     S45A2_HUMAN (see all proteins):
    SLC45A4

    SLC45A2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    S45A2_HUMAN, Q9UMX9: Genetic variants in SLC45A2 define the skin/hair/eye pigmentation variation locus 5 (SHEP5)
    [MIM:227240]. Hair, eye and skin pigmentation are among the most visible examples of human phenotypic variation,
    with a broad normal range that is subject to substantial geographic stratification. In the case of skin,
    individuals tend to have lighter pigmentation with increasing distance from the equator. By contrast, the
    majority of variation in human eye and hair color is found among individuals of European ancestry, with most
    other human populations fixed for brown eyes and black hair


    Selected SNPs for SLC45A2 (see all 1024)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0670714
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0670712 M I mis40--------
    VAR_0227194
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0227192 A T mis40--------
    VAR_0227104
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0227102 P A mis40--------
    VAR_0227204
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0227202 A V mis40--------
    rs289393801,2,4
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0227182 mis40--------
    VAR_0670724
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0670722 G S mis40--------
    VAR_0227174
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0227172 Y C mis40--------
    VAR_0227144
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0227142 W C mis40--------
    VAR_0227134
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0227132 G V mis40--------
    VAR_0227124
    Albinism, oculocutaneous, 4 (OCA4)4--see VAR_0227122 D N mis40--------

    HapMap Linkage Disequilibrium report for SLC45A2 (33944721 - 33984835 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SLC45A2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2730053CNV Deletion23290073
    esv33876CNV Loss17666407
    nsv462115CNV Loss19166990
    nsv830255CNV Loss17160897
    nsv519240CNV Gain19592680
    nsv522715CNV Gain19592680

    Human Gene Mutation Database (HGMD): SLC45A2
    Locus Specific Mutation Databases (LSDB): SLC45A2

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC45A2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606202   
    OMIM disorders: 606574  227240  
    UniProtKB/Swiss-Prot: S45A2_HUMAN, Q9UMX9
  • Albinism, oculocutaneous, 4 (OCA4) [MIM:606574]: A disorder of pigmentation characterized by reduced
    biosynthesis of melanin in the skin, hair and eyes. Patients show reduced or lacking pigmentation associated with
    classic albinism ocular abnormalities, including decreased visual acuity, macular hypoplasia, optic dysplasia,
    atypical choroidal vessels, and nystagmus. Note=The disease is caused by mutations affecting the gene represented
    in this entry

  • 14 diseases for SLC45A2:    
    About MalaCards
    oculocutaneous albinism type 4    melanoma    oculocutaneous albinism type 1    oculocutaneous albinism
    albinism    congenital nystagmus    cutaneous malignant melanoma    ocular albinism
    neutropenia    basal cell carcinoma    choroiditis    multiple myeloma
    myeloma    malaria

    2 diseases from the University of Copenhagen DISEASES database for SLC45A2:
    Oculocutaneous albinism     Ocular albinism

    SLC45A2 for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for SLC45A2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    albinism oculocutaneous 96.2 10 17768386 (2), 18245373 (2), 14722913 (1), 17358008 (1) (see all 6)
    albinism 90.2 1 14722913 (1)
    melanoma 40.1 8 11700328 (2), 18683857 (2), 16116595 (1), 18563784 (1) (see all 5)

    GeneTests: SLC45A2
    GeneReviews: SLC45A2
    Genetic Association Database (GAD): SLC45A2
    Human Genome Epidemiology (HuGE) Navigator: SLC45A2 (24 documents)

    Export disorders for SLC45A2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC45A2 gene, integrated from 10 sources (see all 68):
    (articles sorted by number of sources associating them with SLC45A2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Distribution of the F374 allele of the SLC45A2 (MATP) gene and founder-haplotype analysis. (PubMed id 17044855)1, 2, 4, 9 Yuasa I....Henke J. (Ann. Hum. Genet. 2006)
    2. Single nucleotide polymorphisms in the MATP gene are associated with normal human pigmentation variation. (PubMed id 15714523)1, 2, 4, 9 Graf J.... van Daal A. (Hum. Mutat. 2005)
    3. Mutations in the MATP gene in five German patients affected by oculocutaneous albinism type 4. (PubMed id 14722913)1, 2, 4, 9 Rundshagen U....Kaesmann-Kellner B. (Hum. Mutat. 2004)
    4. A genomewide association study of skin pigmentation in a South Asian population. (PubMed id 17999355)1, 2, 4, 9 Stokowski R.P....Cox D.R. (Am. J. Hum. Genet. 2007)
    5. Mutations in the human orthologue of the mouse underwhite gene (uw) underlie a new form of oculocutaneous albinism, OCA4. (PubMed id 11574907)1, 2, 3, 9 Newton J.M.... Brilliant M.H. (Am. J. Hum. Genet. 2001)
    6. MATP polymorphisms in Germans and Japanese: the L374F mutation as a population marker for Caucasoids. (PubMed id 15455243)1, 2, 4 Yuasa I.... Irizawa Y. (Int. J. Legal Med. 2004)
    7. SLC45A2 variations in Indian oculocutaneous albinism patients. (PubMed id 17768386)1, 2, 9 Sengupta M.... Ray K. (Mol. Vis. 2007)
    8. Promoter polymorphisms in the MATP (SLC45A2) gene are associated with normal human skin color variation. (PubMed id 17358008)1, 4, 9 Graf J....van Daal A. (Hum. Mutat. 2007)
    9. SLC45A2: a novel malignant melanoma-associated gene. (PubMed id 18563784)1, 4, 9 Fernandez L.P....Ribas G. (Hum. Mutat. 2008)
    10. Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma. (PubMed id 19710684)1, 4, 9 Duffy D.L....Montgomery G.W. (J. Invest. Dermatol. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51151 HGNC: 16472 AceView: MATP Ensembl:ENSG00000164175 euGenes: HUgn51151
    ECgene: SLC45A2 H-InvDB: SLC45A2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC45A2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SLC45A2 Genetics and Cytogenetics in Oncology and Haematology
    Mutations of the MATP genehttp://www.retina-international.org/files/sci-news/matpmut.htm
    Albinism database (ADB)http://albinismdb.med.umn.edu/oca4mut.html
    GeneReviewshttp://www.ncbi.nlm.nih.gov/books/NBK1116/?term=SLC45A2[genesymbol]

    (Patent information from GeneIP,
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    Patent Information for SLC45A2 gene:
    Search GeneIP for patents involving SLC45A2

    GeneCards and IP:
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