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SLC44A3 Gene

protein-coding   GIFtS: 53
GCID: GC01P095286

Solute Carrier Family 44, Member 3

(Previous names: solute carrier family, member 3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 44, Member 31 2
CTL32 3
Solute Carrier Family, Member 31
Choline Transporter-Like Protein 32
Solute Carrier Family 44 Member 33

External Ids:    HGNC: 286891   Entrez Gene: 1269692   Ensembl: ENSG000001430367   UniProtKB: Q8N4M13   

Export aliases for SLC44A3 gene to outside databases

Previous GC identifers: GC01P094998 GC01P093407


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SLC44A3 Gene:
SLC44A3 (solute carrier family 44, member 3) is a protein-coding gene. Diseases associated with SLC44A3 include cystinuria, and yellow fever. An important paralog of this gene is SLC44A1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC44A3 gene promoter:
         Egr-2   HOXA9B   HOXA9   Meis-1   Meis-1b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC44A3 promoter sequence
   Search Chromatin IP Primers for SLC44A3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC44A3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p21.3   Ensembl cytogenetic band:  1p21.3   HGNC cytogenetic band: 1p22.1

SLC44A3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC44A3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P095286:  view genomic region     (about GC identifiers)

Start:
95,285,898 bp from pter      End:
95,360,802 bp from pter
Size:
74,905 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CTL3_HUMAN, Q8N4M1 (See protein sequence)
Recommended Name: Choline transporter-like protein 3  
Size: 653 amino acids; 73783 Da
Sequence caution: Sequence=AAH33858.2; Type=Erroneous initiation; Sequence=AAQ89022.1; Type=Erroneous initiation;
Secondary accessions: B4DVY4 B4E1M4 B7ZA08 E9PJH2 E9PJY8 Q6UWT1 Q7Z6C5 Q9BWY7
Alternative splicing: 6 isoforms:  Q8N4M1-1   Q8N4M1-2   Q8N4M1-3   Q8N4M1-4   Q8N4M1-5   Q8N4M1-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC44A3: NX_Q8N4M1

Explore proteomics data for SLC44A3 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn136, Asn151, Asn412, Asn503, Asn521
  • Modification sites at PhosphoSitePlus

  • See SLC44A3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001107578.1  NP_001245269.1  NP_001245270.1  NP_001245271.1  NP_001245272.1  NP_689582.2  

    ENSEMBL proteins: 
     ENSP00000389143   ENSP00000271227   ENSP00000433641   ENSP00000431836   ENSP00000432789  
     ENSP00000410832   ENSP00000436661   ENSP00000434457   ENSP00000432880  
    Reactome Protein details: Q8N4M1

    SLC44A3 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Choline transporter-like 3
    SLC44 family of choline transporters

    1 InterPro protein domain:
     IPR007603 Choline_transptr-like

    Graphical View of Domain Structure for InterPro Entry Q8N4M1

    ProtoNet protein and cluster: Q8N4M1

    UniProtKB/Swiss-Prot: CTL3_HUMAN, Q8N4M1
    Similarity: Belongs to the CTL (choline transporter-like) family


    SLC44A3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 MGI phenotypic allele for Slc44a3 (no phenotypes)

    SLC44A3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Slc44a3tm1Lex for SLC44A3

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC44A3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC44A3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC44A3

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate SLC44A3:
    hsa-miR-3607-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SLC44A3

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    GenScript: all cDNA clones in your preferred vector (see all 2): SLC44A3 (NM_001114106)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC44A3
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC44A3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CTL3_HUMAN, Q8N4M1: Membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    SLC44A3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SLC44A3 About    
    See pathways by source

    SuperPathContained pathways About
    1Glycerophospholipid biosynthesis
    Glycerophospholipid biosynthesis0.64
    Synthesis of PC0.00
    Phospholipid metabolism0.64
    2Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    SLC-mediated transmembrane transport0.47
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.47
    3Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for SLC44A3
        Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Synthesis of PC



    SLC44A3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC44A3
    Interactions:

        Search GeneGlobe Interaction Network for SLC44A3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for SLC44A3 (Q8N4M13 ENSP000002712274) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    ACHEENSP000003032114STRING: ENSP00000303211
    CHATENSP000003371034STRING: ENSP00000337103
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0006656phosphatidylcholine biosynthetic process TAS--
    GO:0044281small molecule metabolic process TAS--
    GO:0046474glycerophospholipid biosynthetic process TAS--
    GO:0055085transmembrane transport TAS--

    SLC44A3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC44A3 (CTL3)

    1 HMDB Compound for SLC44A3    About this table
    CompoundSynonyms CAS #PubMed Ids
    Choline(2-Hydroxyethyl)trimethyl ammonium (see all 19)62-49-7--

    1 DrugBank Compound for SLC44A3    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    CholineBilineurine (see all 7)62-49-7transportersubstrate17520363



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SLC44A3 gene (6 alternative transcripts): 
    NM_001114106.2  NM_001258340.1  NM_001258341.1  NM_001258342.1  NM_001258343.1  NM_152369.4  

    Unigene Cluster for SLC44A3:

    Solute carrier family 44, member 3
    Hs.483423  [show with all ESTs]
    Unigene Representative Sequence: NM_001114106
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000446120 ENST00000271227(uc001dqv.4 uc001dqx.4 uc010otq.2 uc010otr.2 uc001dqw.4 uc010ots.2 uc009wds.3 uc010ott.2)
    ENST00000527077 ENST00000529450 ENST00000467909 ENST00000422520 ENST00000532427
    ENST00000475883 ENST00000530397(uc010otu.1) ENST00000532670
    miRNA
    Products:
         
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    1 qRT-PCR Assays for microRNA that regulate SLC44A3:
    hsa-miR-3607-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 2): SLC44A3 (NM_001114106)
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC44A3
      QuantiFast Probe-based Assays in human, mouse, rat SLC44A3

    Additional mRNA sequence: 

    AK300193.1 AK301288.1 AK302381.1 AK303906.1 AK313574.1 AK316123.1 AY358659.1 BC033858.1 
    BC040448.1 BC053877.1 BX648225.1 

    7 DOTS entries:

    DT.443243  DT.97777431  DT.101981178  DT.95343415  DT.121431672  DT.121431698  DT.91661205 

    Selected AceView cDNA sequences (see all 85):

    AW439737 AA873189 BI766348 CA394765 AW269723 AA604003 CB851041 BM924167 
    BQ425981 AW007109 NM_152369 CA314227 BC033858 AA978030 CR600415 BC053877 
    BI824953 CB118486 AL530322 AW821877 BI763810 AW821881 AL540829 BI765961 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC44A3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17
    SP1:        -                 -                                                                                 
    SP2:              -           -                                                                                 
    SP3:                                                                                                            
    SP4:                                                                                                            


    ECgene alternative splicing isoforms for SLC44A3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC44A3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTTTAACT
    SLC44A3 Expression
    About this image


    SLC44A3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Kidney (Urinary System)
             Ureteric Bud Cells Ureteric Bud
     
     Colon (Gastrointestinal Tract)
     
     Stomach (Gastrointestinal Tract)
    SLC44A3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC44A3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.483423
        Custom PCR Arrays for SLC44A3
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC44A3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC44A3 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc44a31 , 5 solute carrier family 44, member 31, 5 82.39(n)1
    81.26(a)1
      3 (52.94 cM)5
    2136031  NM_145394.31  NP_663369.21 
     1214595295 
    chicken
    (Gallus gallus)
    Aves SLC44A31 solute carrier family 44, member 3 69.61(n)
    65.74(a)
      424486  XM_004936578.1  XP_004936635.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC44A36
    solute carrier family 44, member 3
    62(a)
    1 ↔ 1
    4(89183883-89284533)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG13116
    --
    30(a)
    1 → many
    3L(4277962-4281585)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PNS16
    Protein of unknown function; has similarity to Tor...
    16(a)
    1 → many
    XV(636939-638558) YOR161C


    ENSEMBL Gene Tree for SLC44A3 (if available)
    TreeFam Gene Tree for SLC44A3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC44A3 gene
    SLC44A12  SLC44A52  SLC44A42  SLC44A22  
    3 SIMAP similar genes for SLC44A3 using alignment to 5 protein entries:     CTL3_HUMAN (see all proteins):
    SLC44A1    SLC44A2    SLC44A5

    SLC44A3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SLC44A3
    PGOHUM00000241049


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC44A3 (see all 1821)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1808617471,2
    --93405610(+) CTACAA/GATTTT 5 -- int10--------
    rs38603461,2
    C,F,A,H--93405882(-) TATACA/GATGAA 1 -- us2k123Minor allele frequency- G:0.46NS EA NA WA CSA 2250
    rs38901191,2
    C,F,H--95284105(-) TGTCCA/TGGAAC 6 -- us2k18Minor allele frequency- T:0.43NA CSA WA EA 370
    rs1872313681,2
    --95284122(+) TGGTTC/TCTGGT 6 -- us2k10--------
    rs1921101451,2
    C--95284126(+) TCCTGA/GTCTTT 6 -- us2k10--------
    rs38603471,2
    C,F,H--95284191(-) TGATAC/AAATAG 6 -- us2k120Minor allele frequency- A:0.15NS EA NA WA 2328
    rs38603481,2
    C,H--95284222(-) ATCAAA/GCAAGA 6 -- us2k113Minor allele frequency- G:0.05NA WA CSA EA 378
    rs38901181,2
    C,F--95284230(-) AGGACA/GTAATC 6 -- us2k112Minor allele frequency- G:0.38NA WA CSA EA 375
    rs1836777711,2
    --95284231(+) ATTATA/GTCCTC 6 -- us2k10--------
    rs1876181841,2
    --95284247(+) ATGTCA/GTTCAA 6 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC44A3 (95285898 - 95360802 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SLC44A3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv267890CNV Insertion20981092
    nsv506949CNV Insertion20534489
    esv272153CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC44A3
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC44A3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    6 diseases for SLC44A3:    
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    cystinuria    yellow fever    fanconi's anemia    esophageal squamous cell carcinoma
    esophagitis    squamous cell carcinoma


    SLC44A3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC44A3
    Human Genome Epidemiology (HuGE) Navigator: SLC44A3 (1 document)

    Export disorders for SLC44A3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC44A3 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with SLC44A3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. Molecular characterization of the family of choline transporter-like proteins and their splice variants. (PubMed id 15715662)1, 3 Traiffort E.... Meunier F.-M. (J. Neurochem. 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins. (PubMed id 10677542)1, 2 O'Regan S.... Meunier F.-M. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    7. Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. (PubMed id 23934736)1 Yu B....Boerwinkle E. (Genet. Epidemiol. 2013)
    8. A genome-wide association search for type 2 diabetes genes in African Americans. (PubMed id 22238593)1 Palmer N.D....Sladek R. (PLoS ONE 2012)
    9. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. (PubMed id 21248752)2 Varela I....Futreal P.A. (Nature 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 126969 HGNC: 28689 AceView: MGC45474 Ensembl:ENSG00000143036 euGenes: HUgn126969
    ECgene: SLC44A3 H-InvDB: SLC44A3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC44A3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC44A3 gene:
    Search GeneIP for patents involving SLC44A3

    GeneCards and IP:
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