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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC44A2 Gene

protein-coding   GIFtS: 53
GCID: GC19P010713

solute carrier family 44, member 2
 Explore 6 diseases affiliated with
SLC44A2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SLC44A2    

Aliases
for SLC44A2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Solute Carrier Family 44, Member 21 2
CTL21 2 3 5
PP12922
Choline Transporter-Like Protein 22
Solute Carrier Family 44 Member 23

External Ids:    HGNC: 172921   Entrez Gene: 571532   Ensembl: ENSG000001293537   OMIM: 6061065   UniProtKB: Q8IWA53   

Export aliases for SLC44A2 gene to outside databases

Previous GC identifers: GC19P010575 GC19P010290


Summaries
for SLC44A2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: CTL2_HUMAN, Q8IWA5
Function: Isoform 1, but not isoform 3, exhibits some choline transporter activity

Gene Wiki entry for SLC44A2


Genomic Views
for SLC44A2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011295.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC44A2 gene promoter:
         USF1   Sp1   NF-YA   Ik-2   CBF-A   CBF-B   USF-1   CP1A   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLC44A2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC44A2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC44A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.1   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.1

SLC44A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC44A2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P010713:  view genomic region     (about GC identifiers)

Start:
 10,713,121 bp from pter      End:
 10,755,235 bp from pter
Size:
 42,115 bases      Orientation:
 plus strand

Proteins
for SLC44A2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CTL2_HUMAN, Q8IWA5 (See protein sequence)
Recommended Name: Choline transporter-like protein 2  
Size: 706 amino acids; 80124 Da
Subunit: Interacts with COCH
Subcellular location: Membrane; Multi-pass membrane protein (By similarity)
Sequence caution: Sequence=BAC11662.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B2RBB1 B3KNH3 B4DFJ0 F2Q9D7 Q658V1 Q658Z2 Q6PJV7 Q8N2F0 Q9NY68
Alternative promoter usage, Alternative splicing: 3 isoforms:  Q8IWA5-1   Q8IWA5-2   Q8IWA5-3   (Produced by alternative promoter usage)

Explore the universe of human proteins at neXtProt for SLC44A2: NX_Q8IWA5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8IWA5

    • SLC44A2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001138528.1  NP_065161.3  

    ENSEMBL proteins: 
     ENSP00000468691   ENSP00000385135   ENSP00000336888   ENSP00000465547   ENSP00000467552  
     ENSP00000466664   ENSP00000466612   ENSP00000468070   ENSP00000466575   ENSP00000468812  
    Reactome Protein details: Q8IWA5
    Human Recombinant Protein Products: 
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    Novus Biologicals SLC44A2 Protein
    Novus Biologicals SLC44A2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SLC44A2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane TAS10677542


    SLC44A2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for SLC44A2

    Protein Domains /
    Families
    for SLC44A2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SLC44A2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007603 Choline_transptr-like

    Graphical View of Domain Structure for InterPro Entry Q8IWA5

    ProtoNet protein and cluster: Q8IWA5

    UniProtKB/Swiss-Prot: CTL2_HUMAN, Q8IWA5
    Similarity: Belongs to the CTL (choline transporter-like) family


    Function
    for SLC44A2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CTL2_HUMAN, Q8IWA5
    Function: Isoform 1, but not isoform 3, exhibits some choline transporter activity

    miRNA
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    hsa-miR-140-5p hsa-miR-3673 hsa-miR-642a hsa-miR-4311 hsa-miR-520d-5p hsa-miR-1271 hsa-miR-449a hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmid: SLC44A2 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: SLC44A2
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for SLC44A2

    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity IMP12761501
    GO:0015220choline transmembrane transporter activity TAS10677542


    SLC44A2 for ontologies           About GeneDecksing



    Pathways & Interactions
    for SLC44A2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1SLC-mediated transmembrane transport
    		SLC-mediated transmembrane transport1.00
    		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    		Transmembrane transport of small molecules0.50
    2Glycerophospholipid biosynthesis
    		Glycerophospholipid biosynthesis1.00
    		Phospholipid metabolism0.64
    3Metabolism
    		Metabolism1.00
    		Metabolism of lipids and lipoproteins0.34
    4Amine compound SLC transporters
    		Amine compound SLC transporters1.00
    5Synthesis of PE
    		Synthesis of PC0.30

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/9        Reactome Pathways for SLC44A2 (see all 9)
        Metabolism
    Amine compound SLC transporters
    Phospholipid metabolism
    Synthesis of PC
    Glycerophospholipid biosynthesis



    SLC44A2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC44A2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for SLC44A2 (Q8IWA53 ENSP000003368884) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RBL1P287493I2D: score=1 
    ACHEENSP000003032114STRING: ENSP00000303211
    CHATENSP000003371034STRING: ENSP00000337103
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0006656phosphatidylcholine biosynthetic process TAS--
    GO:0007165signal transduction IMP12761501
    GO:0015871choline transport TAS10677542
    GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascade IMP12761501


    SLC44A2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SLC44A2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC44A2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC44A2

    1 HMDB Compound for SLC44A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Choline(2-Hydroxyethyl)trimethyl ammonium (see all 19)62-49-7--

    1 DrugBank Compound for SLC44A2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    CholineBilineurine (see all 7)62-49-7transportersubstrate17139284 17016423

    1 Novoseek chemical compound relationship for SLC44A2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    choline 67.2 18 20410607 (4), 20040764 (3), 14973250 (2), 19319905 (1) (see all 7)

    Search CenterWatch for drugs/clinical trials and news about SLC44A2 / CTL2 

    Transcripts
    for SLC44A2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SLC44A2 gene (2 alternative transcripts): 
    NM_001145056.1  NM_020428.3  

    Unigene Cluster for SLC44A2:

    Solute carrier family 44, member 2
    Hs.534560  [show with all ESTs]
    Unigene Representative Sequence: NM_020428
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000590382 ENST00000588465 ENST00000407327(uc002mpe.4 uc002mpg.1 uc002mph.3 uc002mpi.3)
    ENST00000335757(uc002mpf.3) ENST00000590857 ENST00000588688 ENST00000586078
    ENST00000592293 ENST00000588409 ENST00000588393 ENST00000589561 ENST00000588214
    ENST00000591194 ENST00000586549 ENST00000590475

    miRNA
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    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC44A2 (see all 22):
    hsa-miR-140-5p hsa-miR-3673 hsa-miR-642a hsa-miR-4311 hsa-miR-520d-5p hsa-miR-1271 hsa-miR-449a hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmid: SLC44A2 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC44A2 (see all 7)
    OriGene shRNA RFP: SLC44A2
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    Clone
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    Additional cDNA sequence: 

    AF070636.1 AF258549.1 AK027519.1 AK075512.1 AK126550.1 AK294118.1 AK309801.1 AK314582.1 
    AL832517.1 AL832978.1 BC010617.2 BC020511.1 BC040556.1 BC042692.1 FN668568.1 

    24/30 DOTS entries (see all 30):

    DT.102833692  DT.95355206  DT.95355268  DT.441730  DT.92459939  DT.100799933  DT.100833552  DT.100821485 
    DT.100821488  DT.101985238  DT.75125134  DT.97768532  DT.121484197  DT.95355285  DT.100821481  DT.121484204 
    DT.91718975  DT.121484147  DT.121484169  DT.100821482  DT.121484144  DT.121484209  DT.121484217  DT.92459937 

    24/656 AceView cDNA sequences (see all 656):

    BM463400 Z40821 BU186009 CA487420 AL556606 BM051625 BE294075 BU153735 
    BG741388 CR625042 AW408627 BQ717663 CN484075 BE295971 AA774640 AL549526 
    BI829961 R84842 CF139049 BQ960387 AL832517 CF265145 BM718029 AI033317 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SLC44A2 (see all 11)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^ 14a · 14b · 14c ^ 15a · 15b ^ 16a · 16b · 16c ·
    SP1:                                                                                                                          -     -           -               
    SP2:        -     -                                                                                                           -     -           -               
    SP3:                                                                                                                          -     -           -               
    SP4:                                                                                                                          -     -           -               
    SP5:                                                                                                                                                            

    ExUns: 16d · 16e ^ 17a · 17b · 17c ^ 18a · 18b · 18c ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b ^ 24a · 24b
    SP1:                                                                          -     -               
    SP2:                                                                          -     -               
    SP3:        -     -                                                           -     -               
    SP4:                                                                                                
    SP5:                                                                                                


    ECgene alternative splicing isoforms for SLC44A2

    Expression
    for SLC44A2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC44A2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CATTAAAGGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SLC44A2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC44A2

    SOURCE GeneReport for Unigene cluster: Hs.534560

    UniProtKB/Swiss-Prot: CTL2_HUMAN, Q8IWA5
    Tissue specificity: Present in supporting cells of the inner ear (at protein level). Only isoform 3 is expressed in
    inner ear vestibular tissue

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    In Situ
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    Orthologs
    for SLC44A2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC44A2 gene from 8/26 species (see all 26)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Slc44a21 , 5 solute carrier family 44, member 21, 5 85.13(n)1
    90.93(a)1    		   9 (7.77 cM)5
    686821  NM_152808.31  NP_690021.11 
     213378285 
    lizard
    (Anolis carolinensis)    		 Reptilia SLC44A26
    		 --
    		 80(a)
    		 1 ↔ 1
    		 2(80526168-80563913)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BJ042568.12   -- 78.79(n)    BJ042568.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii sbcb392 sbcb39 75.6(n)   321056  BC054915.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG118806
    		 --
    		 31(a)
    		 possible ortholog
    		 3R(24949104-24953972)
    worm
    (Caenorhabditis elegans)    		 Secernentea chtl-16
    		 Choline transporter-like protein 1
    		 33(a)
    		 possible ortholog
    		 X(5355602-5364290)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT3G153801 Plasma-membrane choline transporter family protein 42.61(n)
    27.52(a)    		   820777  NM_112406.4  NP_566511.1 
    rice
    (Oryza sativa)    		 Liliopsida Os04g06814001 hypothetical protein 43.37(n)
    28.66(a)    		   4337431  NM_001060824.1  NP_001054289.1 


    ENSEMBL Gene Tree for SLC44A2 (if available)
    TreeFam Gene Tree for SLC44A2 (if available) 

    Paralogs
    for SLC44A2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC44A2 gene
    SLC44A12  SLC44A52  SLC44A32  SLC44A42  
    4 SIMAP similar genes for SLC44A2 using alignment to 8 protein entries:     CTL2_HUMAN (see all proteins):
    SLC44A5    SLC44A3    SLC44A4    SLC44A1

    SLC44A2 for paralogs           About GeneDecksing



    Genomic Variants
    for SLC44A2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/806 NCBI SNPs in SLC44A2 are shown (see all 806)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs353403691,2
    		C--10320925(+) CTTTC-/TTTTTT 1 -- int12Minor allele frequency- T:0.00NA CSA 4
    rs342771291,2
    		C,--10327668(+) GGGGG-/GTCCAG 1 -- int13Minor allele frequency- G:0.17NA CSA 6
    rs1388752411,2
    		--10711164(+) CACCAA/GTGATC 1 -- us2k10--------
    rs1494092211,2
    		--10711393(+) CACCAA/GCAGTG 1 -- us2k10--------
    rs1871377031,2
    		--10711436(+) CAACAC/TTTGGT 1 -- us2k10--------
    rs757760961,2
    		--10711473(+) TTCAGG/CTGGGT 1 -- us2k11Minor allele frequency- C:0.01NA 120
    rs2006156031,2
    		--10711542(+) TCTTT-/TTTC  
                TTTCT     		1 -- us2k10--------
    rs2016578211,2
    		--10711561(+) TCTTT-/CTTTTT 1 -- us2k10--------
    rs343182611,2
    		C,--10711733(+) GCAACT/CTCCAC 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs1920915131,2
    		--10711754(+) CAAGCC/GATTCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC44A2 (10713121 - 10755235 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SLC44A2: --
    Human Gene Mutation Database (HGMD): SLC44A2

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    Disorders / Diseases
    for SLC44A2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SLC44A2 for disorders           About GeneDecksing

    OMIM gene information: 606106    OMIM disorders: --

    6 diseases for SLC44A2:    About MalaCards
    hearing loss    chronic lymphocytic leukemia    lymphocytic leukemia    colon carcinoma
    leukemia    carcinoma

    Human Genome Epidemiology (HuGE) Navigator: SLC44A2 (1 document)

    Export disorders for SLC44A2 gene to outside databases

    Publications
    for SLC44A2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC44A2 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with SLC44A2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins. (PubMed id 10677542)1, 2, 3 O'Regan S.... Meunier F.-M. (2000)
    2. Identification and characterization of choline transporter-like protein 2, an inner ear glycoprotein of 68 and 72 kDa that is the target of antibody-induced hearing loss. (PubMed id 14973250)1, 2, 9 Nair T.S.... Carey T.E. (2004)
    3. Cochlin isoforms and their interaction with CTL2 (SLC44A2) in the inner ear. (PubMed id 17926100)1, 2, 9 Kommareddi P.K.... Carey T.E. (2007)
    4. Isoforms, expression, glycosylation, and tissue distr ibution of CTL2/SLC44A2. (PubMed id 20665236)1, 2 Kommareddi P.K....Carey T.E. (2010)
    5. Molecular characterization of the family of choline transporter-like proteins and their splice variants. (PubMed id 15715662)1, 3 Traiffort E....Meunier F.M. (2005)
    6. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. Involvement of choline transporter-like proteins, CTL 1 and CTL2, in glucocorticoid-induced acceleration of phosphatidylcholine synth esis via increased choline uptake. (PubMed id 20410607)1, 9 Nakamura T....Tamai I. (2010)
    10. The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 am ino acid substitution. (PubMed id 20040764)1, 9 Curtis B.R....Aster R.H. (2010)

    External Searches for SLC44A2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SLC44A2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57153 HGNC: 17292 AceView: CTL2 Ensembl:ENSG00000129353 euGenes: HUgn57153
    ECgene: SLC44A2 H-InvDB: SLC44A2

    Other Databases showing SLC44A2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SLC44A2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC44A2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SLC44A2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SLC44A2 gene:
    Search GeneIP for patents involving SLC44A2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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