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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC44A1 Gene

protein-coding   GIFtS: 58
GCID: GC09P108006

Solute Carrier Family 44 (Choline Transporter), Member 1

(Previous name: CDW92 antigen)
(Previous symbol: CDW92)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 44 (Choline Transporter), Member 11 2     RP11-287A8.12
CDW921 2 3 5     Choline Transporter-Like Protein 12
CTL12 3 5     Solute Carrier Family 44, Member 12
CDW92 Antigen1 2     CDw923
CD922 3     CD92 Antigen3
CHTL12     Solute Carrier Family 44 Member 13

External Ids:    HGNC: 187981   Entrez Gene: 234462   Ensembl: ENSG000000702147   OMIM: 6061055   UniProtKB: Q8WWI53   

Export aliases for SLC44A1 gene to outside databases

Previous GC identifers: GC09P105087 GC09P107046 GC09P077662


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SLC44A1 Gene: 
SLC44A1 (solute carrier family 44 (choline transporter), member 1) is a protein-coding gene. Diseases associated with SLC44A1 include lung adenocarcinoma, and neuroblastoma, and among its related super-pathways are Transmembrane transport of small molecules and Glycerophospholipid biosynthesis. GO annotations related to this gene include choline transmembrane transporter activity. An important paralog of this gene is SLC44A5.

UniProtKB/Swiss-Prot: CTL1_HUMAN, Q8WWI5
Function: Choline transporter. May be involved in membrane synthesis and myelin production

Gene Wiki entry for SLC44A1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_008470.19  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC44A1 gene promoter:
         CUTL1   POU3F2   AP-2gamma   POU2F1   POU2F1a   AP-2beta   Chx10   AP-2alpha   AP-2alphaA   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SLC44A1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC44A1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q31.2   Ensembl cytogenetic band:  9q31.1   HGNC cytogenetic band: 9q31.2

SLC44A1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC44A1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P108006:  view genomic region     (about GC identifiers)

Start:
108,006,903 bp from pter      End:
108,201,452 bp from pter
Size:
194,550 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CTL1_HUMAN, Q8WWI5 (See protein sequence)
Recommended Name: Choline transporter-like protein 1  
Size: 657 amino acids; 73302 Da
Subcellular location: Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass
membrane protein
Secondary accessions: A6NLZ9 Q5VUB3 Q8WVB0 Q96KU3 Q9NY69
Alternative splicing: 3 isoforms:  Q8WWI5-1   Q8WWI5-2   Q8WWI5-3   

Explore the universe of human proteins at neXtProt for SLC44A1: NX_Q8WWI5

Explore proteomics data for SLC44A1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WWI5

  • SLC44A1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC44A1 Protein Expression
    REFSEQ proteins: NP_536856.2  
    ENSEMBL proteins: 
     ENSP00000363855   ENSP00000433072   ENSP00000363852   ENSP00000363856   ENSP00000341856  
    Reactome Protein details: Q8WWI5
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005741mitochondrial outer membrane IEA--
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane TAS10677542

    SLC44A1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CD: CD molecules
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Choline transporter-like 1 
    SLC44 family of choline transporters

    1 InterPro protein domain:
     IPR007603 Choline_transptr-like

    Graphical View of Domain Structure for InterPro Entry Q8WWI5

    ProtoNet protein and cluster: Q8WWI5

    UniProtKB/Swiss-Prot: CTL1_HUMAN, Q8WWI5
    Similarity: Belongs to the CTL (choline transporter-like) family


    SLC44A1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CTL1_HUMAN, Q8WWI5
    Function: Choline transporter. May be involved in membrane synthesis and myelin production

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015220choline transmembrane transporter activity TAS10677542
         
    SLC44A1 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC44A1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.50
    2Glycerophospholipid biosynthesis
    Glycerophospholipid biosynthesis0.64
    Phospholipid metabolism0.64
    3Metabolism
    Metabolism0.40
    Metabolism of lipids and lipoproteins0.34
    4Amine compound SLC transporters
    Amine compound SLC transporters0.63
    5Synthesis of PE
    Synthesis of PC0.30

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    5/9        Reactome Pathways for SLC44A1 (see all 9)
        Metabolism
    Amine compound SLC transporters
    Phospholipid metabolism
    Synthesis of PC
    Glycerophospholipid biosynthesis



    SLC44A1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC44A1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/33 Interacting proteins for SLC44A1 (Q8WWI52, 3 ENSP000003638524) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    C11orf58O001932, 3MINT-8249909 I2D: score=2 
    KCNE3Q9Y6H62, 3MINT-8259139 I2D: score=2 
    NUDT21O438092, 3MINT-8264556 I2D: score=2 
    MAP4K3Q8IVH83I2D: score=2 
    GBASO753233I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0006656phosphatidylcholine biosynthetic process TAS--
    GO:0015871choline transport TAS10677542
    GO:0044281small molecule metabolic process TAS--
    GO:0046474glycerophospholipid biosynthetic process TAS--

    SLC44A1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SLC44A1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC44A1 (CTL1)

    1 HMDB Compound for SLC44A1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Choline(2-Hydroxyethyl)trimethyl ammonium (see all 19)62-49-7--

    1 DrugBank Compound for SLC44A1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    CholineBilineurine (see all 7)62-49-7transportersubstrate17520363 17624579 16000150 16319125

    1 IUPHAR Ligand for SLC44A1 (Choline transporter-like 1)    About this table 
    LigandTypeActionAffinityPubmed IDs
    hemicholinium-3
    InhibitorInhibition3.5 - 4.5--

    1 Novoseek inferred chemical compound relationship for SLC44A1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    choline 79.2 54 16319125 (5), 19246089 (4), 19135976 (3), 20410607 (3) (see all 11)

    Search CenterWatch for drugs/clinical trials and news about SLC44A1 / CTL1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC44A1 gene (2 alternative transcripts): 
    NM_022109.2  NM_080546.3  

    Unigene Cluster for SLC44A1:

    Solute carrier family 44, member 1
    Hs.573495  [show with all ESTs]
    Unigene Representative Sequence: NM_080546
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374723 ENST00000470972 ENST00000374720(uc004bcn.3) ENST00000374724
    ENST00000607692 ENST00000607701 ENST00000436716 ENST00000343170(uc004bco.1)

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    Additional mRNA sequence: 

    AJ272365.1 AJ420812.1 AK000109.1 AK022549.1 AK124926.1 BC018213.1 BC049203.1 

    19 DOTS entries:

    DT.99935125  DT.100641268  DT.448846  DT.75135392  DT.91736239  DT.95131203  DT.312497  DT.92450007 
    DT.95131192  DT.97784636  DT.121204719  DT.121204758  DT.75149766  DT.92450004  DT.92450013  DT.95131201 
    DT.97847958  DT.100795900  DT.432420 

    24/388 AceView cDNA sequences (see all 388):

    AI818580 BQ719350 W49553 BM829784 AU125248 BI495559 BE302809 AA120951 
    AL707392 AW059547 AU119372 BI762353 CB216865 CB851595 BM980171 AI654542 
    CB216185 AI752936 BX477394 AW058478 AA922927 AI827411 AI468836 BQ775525 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SLC44A1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b · 19c ^ 20
    SP1:                                      -           -                                                           -                                 
    SP2:                                      -           -                                                           -     -     -                     
    SP3:                                                  -                                                           -     -     -     -     -         
    SP4:                                                                                                                                                
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for SLC44A1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC44A1 expression in normal human tissues (normalized intensities)      SLC44A1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAACAAGTTT
    SLC44A1 Expression
    About this image


    SLC44A1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             Thoracic Rib
             skeleton/cranium/viscerocranium   
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Myelinating Oligodendrocyte Cells Forebrain White Matter
             Medulla Oblongata
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 2 entries
             Hindgut
     
     Neural Crest (Gastrulation Derivatives)
             skeleton/cranium/viscerocranium   
     
     Cartilage (Muscoskeletal System)
             skeleton/cranium/viscerocranium   

    See SLC44A1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC44A1

    SOURCE GeneReport for Unigene cluster: Hs.573495

    UniProtKB/Swiss-Prot: CTL1_HUMAN, Q8WWI5
    Tissue specificity: Expressed in various cells of the hematopoietic system

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SLC44A1 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc44a11 , 5 solute carrier family 44, member 11, 5 91.11(n)1
    96.15(a)1
      4 (28.66 cM)5
    1004341  NM_133891.31  NP_598652.31 
     534404135 
    chicken
    (Gallus gallus)
    Aves SLC44A11 solute carrier family 44, member 1 83.03(n)
    88.46(a)
      427301  XM_003643040.1  XP_003643088.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC44A16
    solute carrier family 44, member 1
    88(a)
    1 ↔ 1
    GL343218.1(1005280-1126632)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.164812 Xenopus laevis transcribed sequence with strong similarity more 81.49(n)    BJ622552.1 
    zebrafish
    (Danio rerio)
    Actinopterygii slc44a1a1 solute carrier family 44, member 1a 66.25(n)
    72.49(a)
      100333377  XM_002660581.2  XP_002660627.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG13111 CG1311 49.69(n)
    38.82(a)
      38523  NM_139627.1  NP_647884.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PNS16
    Protein of unknown function; has similarity to Tor...
    14(a)
    1 → many
    XV(636939-638558)


    ENSEMBL Gene Tree for SLC44A1 (if available)
    TreeFam Gene Tree for SLC44A1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC44A1 gene
    SLC44A52  SLC44A32  SLC44A42  SLC44A22  
    3 SIMAP similar genes for SLC44A1 using alignment to 2 protein entries:     CTL1_HUMAN (see all proteins):
    SLC44A3    SLC44A2    SLC44A5

    SLC44A1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2896 SNPs in SLC44A1 are shown (see all 2896)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs70419791,2
    C,F--108005214(+) CTTTTC/TCTTGT 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1442937971,2
    --108005267(+) ATTGGG/TACTAG 1 -- us2k10--------
    rs1846909131,2
    --108005302(+) TGTATG/TTATTG 1 -- us2k10--------
    rs735085911,2
    C,F--108005356(+) TGGTAC/TGGTGG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1478363211,2
    --108005412(+) TTCAAG/TATCTC 1 -- us2k10--------
    rs1808334771,2
    --108005504(+) TACCAA/GCATTT 1 -- us2k10--------
    rs1396675421,2
    --108005792(+) CCCTTC/GCAGCT 1 -- us2k10--------
    rs2002837231,2
    C--108005840(-) TGTCTA/CAAAAG 1 -- us2k10--------
    rs101212641,2
    C--108005857(+) GACAAG/AATGAA 1 -- us2k12Minor allele frequency- A:0.00NA 4
    rs1180880821,2
    F--108005875(+) ATGAAA/GGCTAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SLC44A1 (108006903 - 108201452 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for SLC44A1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2738882CNV Deletion23290073
    esv2657248CNV Deletion23128226
    nsv893689CNV Loss21882294
    nsv893685CNV Loss21882294
    dgv8271n71CNV Loss21882294
    nsv893691CNV Loss21882294
    nsv831678CNV Gain+Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606105    OMIM disorders: --

    5 diseases for SLC44A1:    About MalaCards
    lung adenocarcinoma    neuroblastoma    adenocarcinoma    cervicitis
    neuronitis


    SLC44A1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC44A1

    Export disorders for SLC44A1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC44A1 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with SLC44A1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells. (PubMed id 11698453)1, 2, 3, 9 Wille S.... Stockinger H. (2001)
    2. An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins. (PubMed id 10677542)1, 2, 3 O'Regan S.... Meunier F.-M. (2000)
    3. Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages. (PubMed id 16319125)1, 7, 9 Fullerton M.D....Bakovic M. (2006)
    4. Meta-analysis of genome-wide association data identif ies two loci influencing age at menarche. (PubMed id 19448620)1, 4 Perry J.R....Murabito J.M. (2009)
    5. The solute carrier 44A1 is a mitochondrial protein an d mediates choline transport. (PubMed id 19357133)1, 2 Michel V. and Bakovic M. (2009)
    6. Molecular characterization of the family of choline transporter-like proteins and their splice variants. (PubMed id 15715662)1, 2 Traiffort E....Meunier F.M. (2005)
    7. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Detection of choline transporter-like 1 protein CTL1 in neuroblastoma x glioma cells and in the CNS, and its role in choline uptake. (PubMed id 19519661)1, 9 MachovA! E....Dolezal V. (2009)
    10. Involvement of choline transporter-like proteins, CTL 1 and CTL2, in glucocorticoid-induced acceleration of phosphatidylcholine synth esis via increased choline uptake. (PubMed id 20410607)1, 9 Nakamura T....Tamai I. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23446 HGNC: 18798 AceView: CDW92 Ensembl:ENSG00000070214 euGenes: HUgn23446
    ECgene: SLC44A1 H-InvDB: SLC44A1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC44A1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC44A1 gene:
    Search GeneIP for patents involving SLC44A1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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