Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC41A2 Gene

protein-coding   GIFtS: 49
GCID: GC12M105197

Solute Carrier Family 41 (Magnesium Transporter), Member...

(Previous names: solute carrier family 41, member 2)
  Search for SLC41A2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 41 (Magnesium Transporter), Member 21 2
Solute Carrier Family 41, Member 21 2
SLC41A1-L12
SLC41A1-Like 12
Solute Carrier Family 41 Member 22

External Ids:    HGNC: 310451   Entrez Gene: 841022   Ensembl: ENSG000001360527   OMIM: 6108025   UniProtKB: Q96JW43   

Export aliases for SLC41A2 gene to outside databases

Previous GC identifers: GC12M103701 GC12M103702 GC12M102256


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SLC41A2 Gene: 
SLC41A2 (solute carrier family 41 (magnesium transporter), member 2) is a protein-coding gene. Among its related super-pathways are Transmembrane transport of small molecules and Zinc transporters. GO annotations related to this gene include cation transmembrane transporter activity. An important paralog of this gene is SLC41A3.

UniProtKB/Swiss-Prot: S41A2_HUMAN, Q96JW4
Function: Acts as a plasma-membrane magnesium transporter




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC41A2 gene promoter:
         AREB6   TBP   S8   Nkx2-5   POU6F1 (c2)   E4BP4   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC41A2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC41A2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC41A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q23.3   Ensembl cytogenetic band:  12q23.3   HGNC cytogenetic band: 12q24.11

SLC41A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC41A2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M105197:  view genomic region     (about GC identifiers)

Start:
105,196,331 bp from pter      End:
105,352,522 bp from pter
Size:
156,192 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: S41A2_HUMAN, Q96JW4 (See protein sequence)
Recommended Name: Solute carrier family 41 member 2  
Size: 573 amino acids; 62473 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAH36734.1; Type=Erroneous initiation; Sequence=AAI06872.2; Type=Erroneous initiation;
Sequence=AAI06873.2; Type=Erroneous initiation; Sequence=BAB55402.1; Type=Frameshift; Positions=69, 101, 103;
Sequence=CAB66762.1; Type=Erroneous initiation;
Secondary accessions: Q3KP68 Q9H0E5

Explore the universe of human proteins at neXtProt for SLC41A2: NX_Q96JW4

Explore proteomics data for SLC41A2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96JW4

  • SLC41A2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC41A2 Protein Expression
    REFSEQ proteins: NP_115524.3  
    ENSEMBL proteins: 
     ENSP00000258538   ENSP00000391377   ENSP00000396429   ENSP00000407898   ENSP00000414526  
     ENSP00000395550   ENSP00000397315   ENSP00000396297   ENSP00000410625  
    Reactome Protein details: Q96JW4
    Human Recombinant Protein Products for SLC41A2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for SLC41A2
    GenScript Custom Purified and Recombinant Proteins Services for SLC41A2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC41A2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--

    SLC41A2 for ontologies           About GeneDecksing



    SLC41A2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SLC41A2
    GenScript Custom Superior Antibodies Services for SLC41A2
    Novus Biologicals SLC41A2 Antibodies
    Abcam antibodies for SLC41A2
    Cloud-Clone Corp. Antibodies for SLC41A2 
    Search ThermoFisher Antibodies for SLC41A2
    LSBio Antibodies in human, mouse, rat for SLC41A2 

    Assay Products for SLC41A2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SLC41A2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SLC41A2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SLC41A2 
    Cloud-Clone Corp. CLIAs for SLC41A2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: SLC41A2 
    SLC41 family of divalent cation transporters

    1 InterPro protein domain:
     IPR006667 SLC41_membr_dom

    Graphical View of Domain Structure for InterPro Entry Q96JW4

    ProtoNet protein and cluster: Q96JW4

    UniProtKB/Swiss-Prot: S41A2_HUMAN, Q96JW4
    Similarity: Belongs to the SLC41A transporter family


    SLC41A2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S41A2_HUMAN, Q96JW4
    Function: Acts as a plasma-membrane magnesium transporter

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008324cation transmembrane transporter activity IEA--
         
    SLC41A2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SLC41A2:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC41A2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SLC41A2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC41A2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC41A2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC41A2
    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC41A2 (see all 22):
    hsa-miR-30c hsa-miR-140-5p hsa-miR-15a hsa-miR-10b hsa-miR-944 hsa-miR-30d hsa-miR-29b-1* hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidSLC41A2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SLC41A2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC41A2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SLC41A2
    Sirion Biotech Customized adenovirus for overexpression of SLC41A2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for SLC41A2 (see all 10)
    OriGene ORF clones in mouse, rat for SLC41A2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLC41A2 (NM_032148)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC41A2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC41A2
    Sirion Biotech Customized lentivirus for stable overexpression of SLC41A2 
                         Customized lentivirus expression plasmids for stable overexpression of SLC41A2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SLC41A2
    Search LifeMap BioReagents cell lines for SLC41A2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC41A2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC41A2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
    Transmembrane transport of small molecules0.50
    2Zinc transporters
    Metal ion SLC transporters0.68

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for SLC41A2
        SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
    Metal ion SLC transporters



    SLC41A2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC41A2

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0055085transmembrane transport TAS--

    SLC41A2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC41A2 (S41A2)

    1 HMDB Compound for SLC41A2    About this table
    CompoundSynonyms CAS #PubMed Ids
    MagnesiumMagnesium (see all 2)7439-95-4--

    Search CenterWatch for drugs/clinical trials and news about SLC41A2 / S41A2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC41A2 gene: 
    NM_032148.3  

    Unigene Cluster for SLC41A2:

    Solute carrier family 41, member 2
    Hs.577463  [show with all ESTs]
    Unigene Representative Sequence: NM_032148
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258538(uc001tla.3) ENST00000549713 ENST00000437220 ENST00000415674
    ENST00000411411 ENST00000449866 ENST00000433540 ENST00000424946 ENST00000417469
    ENST00000432951
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC41A2
    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC41A2 (see all 22):
    hsa-miR-30c hsa-miR-140-5p hsa-miR-15a hsa-miR-10b hsa-miR-944 hsa-miR-30d hsa-miR-29b-1* hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidSLC41A2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SLC41A2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC41A2
    Clone
    Products:
         
    OriGene clones in human, mouse for SLC41A2 (see all 10)
    OriGene ORF clones in mouse, rat for SLC41A2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLC41A2 (NM_032148)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC41A2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC41A2
    Sirion Biotech Customized lentivirus for stable overexpression of SLC41A2 
                         Customized lentivirus expression plasmids for stable overexpression of SLC41A2 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SLC41A2
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC41A2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC41A2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC41A2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC41A2

    Additional mRNA sequence: 

    AK027838.1 AL136828.1 BC036734.1 BC106871.1 BC106872.1 

    6 DOTS entries:

    DT.40123011  DT.307211  DT.100736414  DT.121190669  DT.121190664  DT.97779819 

    24/50 AceView cDNA sequences (see all 50):

    AK027838 BG562989 AL136828 AA455987 BX114417 BF589238 BU753775 CA438691 
    AW016390 AI471124 AA938600 CB962857 BG623531 BI913563 BF432428 CB145616 
    AI245600 BU753121 AI366515 CA941943 AI419596 AI400772 NM_032148 AI683853 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC41A2 expression in normal human tissues (normalized intensities)      SLC41A2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTAAGTTG
    SLC41A2 Expression
    About this image


    SLC41A2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Ovary (Reproductive System)
             Pre-Granulosa Cells Primordial Follicle
     
     Kidney (Urinary System)
             Podocytes Podocyte Layer
     
     Blood (Hematopoietic System)
             pre Conventional Dendritic Cells Peripheral Blood
     
     Choroid Plexus (Nervous System)
             Mature Choroid Plexus Cells Choroid Plexus
     
     Brain (Nervous System)
             Mature Choroid Plexus Cells Choroid Plexus

    See SLC41A2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC41A2

    SOURCE GeneReport for Unigene cluster: Hs.577463
        SABiosciences Custom PCR Arrays for SLC41A2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SLC41A2
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC41A2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC41A2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC41A2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC41A2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC41A2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SLC41A2 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc41a21 , 5 solute carrier family 41, member 21, 5 84.03(n)1
    91.26(a)1
      10 (41.03 cM)5
    3383651  NM_177388.31  NP_796362.11 
     832308485 
    chicken
    (Gallus gallus)
    Aves SLC41A21 solute carrier family 41, member 2 79.87(n)
    84.82(a)
      427913  NM_001031483.1  NP_001026654.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC41A26
    Uncharacterized protein
    85(a)
    1 ↔ 1
    5(18630471-18667765)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.42632 Transcribed sequence with weak similarity to protein more 80.41(n)    AL884650.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5662421 solute carrier family 41 member 2-like 69.38(n)
    79.07(a)
      566242  XM_689511.3  XP_694603.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG331811 CG33181 48.71(n)
    44.26(a)
      318916  NM_176712.2  NP_788885.1 
    worm
    (Caenorhabditis elegans)
    Secernentea K07H8.26
    ZK185.26
    (see all 3)
    Protein ZK185.2
    (see all 3)
    39(a)
    32(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    IV(8291539-8294596)
    IV(4536553-4541771)


    ENSEMBL Gene Tree for SLC41A2 (if available)
    TreeFam Gene Tree for SLC41A2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC41A2 gene
    SLC41A32  SLC41A12  
    2 SIMAP similar genes for SLC41A2 using alignment to 9 protein entries:     S41A2_HUMAN (see all proteins):
    SLC41A1    SLC41A3

    SLC41A2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SLC41A2
    PGOHUM00000259271


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2294 SNPs in SLC41A2 are shown (see all 2294)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1413311241,2
    --105196844(+) ATATTA/GTGTGT 1 -- int10--------
    rs1867832821,2
    C--105196911(+) GCTTGC/TCCTGT 1 -- int10--------
    rs1896869021,2
    --105196923(+) TATTTC/TTTAAA 1 -- int10--------
    rs1392742181,2
    C--105197033(+) ATGGA-/TTTTTTTA 1 -- int10--------
    rs1164485931,2
    F--105197054(+) ATCTTT/CGCAGC 1 -- int11Minor allele frequency- C:0.02WA 118
    rs1168874591,2
    F--105197066(+) AAATAT/CTCATC 1 -- int11Minor allele frequency- C:0.03NA 120
    rs1502002241,2
    --105197101(+) TAAGAA/CTGTTC 1 -- int10--------
    rs776971071,2
    C,F--105197406(+) TAACGG/ATCTTG 1 -- ut311Minor allele frequency- A:0.13EA 120
    rs1159176281,2
    C,F--105197647(+) GTCAAC/TGGGCT 1 -- ut311Minor allele frequency- T:0.02WA 118
    rs79581581,2
    C,F,H--105197677(+) ATCACT/CTGCTC 1 -- ut316Minor allele frequency- C:0.02NS EA WA 538

    HapMap Linkage Disequilibrium report for SLC41A2 (105196331 - 105352522 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for SLC41A2:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv269511CNV Insertion20981092
    nsv899497CNV Loss21882294
    nsv899498CNV Gain21882294
    nsv899496CNV Gain21882294
    nsv832505CNV Gain17160897
    nsv899495CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC41A2
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC41A2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SLC41A2 for disorders           About MalaCards
    OMIM gene information: 610802    OMIM disorders: --


    SLC41A2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SLC41A2

    Export disorders for SLC41A2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC41A2 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with SLC41A2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    3. SLC41A2 encodes a plasma-membrane Mg2+ transporter. (PubMed id 16984228)2, 9 Sahni J.... Scharenberg A.M. (2007)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    5. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (2007)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. Functional characterization of the mouse [corrected] solute carrier, SLC41A2. (PubMed id 15809054)1 Goytain A. and Quamme G.A. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. The human solute carrier SLC41A1 belongs to a novel eukaryotic subfamily with homology to prokaryotic MgtE Mg2+ transporters. (PubMed id 12810078)1 Wabakken T.... Aasheim H.-C. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84102 HGNC: 31045 AceView: SLC41A2 Ensembl:ENSG00000136052 euGenes: HUgn84102
    ECgene: SLC41A2 H-InvDB: SLC41A2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC41A2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC41A2 gene:
    Search GeneIP for patents involving SLC41A2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SLC41A2  
     OriGene qPCR primer pairs and template standards for SLC41A2   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SLC41A2  
     OriGene qSTAR qPCR primer pairs in human, mouse for SLC41A2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SLC41A2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SLC41A2   OriGene Custom Protein Services for SLC41A2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC41A2
     QIAGEN SeqTarget long-range PCR primers for resequencing SLC41A2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC41A2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC41A2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC41A2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC41A2
     GenScript Custom Purified and Recombinant Proteins Services for SLC41A2 GenScript cDNA clones with any tag delivered in your preferred vector for SLC41A2
     GenScript Custom Assay Services for SLC41A2 GenScript Custom Superior Antibodies Services for SLC41A2
     GenScript Custom overexpressing Cell Line Services for SLC41A2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SLC41A2 promoter
     Search Chromatin IP Primers for SLC41A2
     RT2 qPCR Primer Assay in human, mouse, rat SLC41A2
     Search GNC Networks for SLC41A2
     SABiosciences Custom PCR Arrays for SLC41A2
     Search Tocris compounds for SLC41A2 (S41A2)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     SLC41A2 antibodies
     Antibodies for SLC41A2
     See all of Abcam's Antibodies, Kits and Proteins for SLC41A2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for SLC41A2
     Antibodies for SLC41A2
     ELISAs for SLC41A2
     CLIAs for SLC41A2
     Search LifeMap BioReagents cell lines for SLC41A2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC41A2
     SwitchGear 3'UTR luciferase reporter plasmids for SLC41A2
     SwitchGear Promoter luciferase reporter plasmids for SLC41A2
     Search ThermoFisher Antibodies for SLC41A2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC41A2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC41A2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SLC41A2
    Customized:
     lentivirus for stable overexpression of SLC41A2
     lentivirus expression plasmids for stable overexpression of SLC41A2
     adenovirus for overexpression of SLC41A2
     LSBio Antibodies in human, mouse, rat for SLC41A2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SLC41A2 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4