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Aliases for SLC39A9 Gene

Aliases for SLC39A9 Gene

  • Solute Carrier Family 39, Member 9 2 3
  • Zrt- And Irt-Like Protein 9 3 4
  • ZIP-9 3 4
  • ZIP9 3 4
  • Solute Carrier Family 39 (Zinc Transporter), Member 9 3
  • Solute Carrier Family 39 Member 9 4
  • Zinc Transporter SLC39A9 3
  • Zinc Transporter ZIP9 3

External Ids for SLC39A9 Gene

Summaries for SLC39A9 Gene

GeneCards Summary for SLC39A9 Gene

SLC39A9 (Solute Carrier Family 39, Member 9) is a Protein Coding gene. GO annotations related to this gene include metal ion transmembrane transporter activity.

UniProtKB/Swiss-Prot for SLC39A9 Gene

  • May act as a zinc-influx transporter.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC39A9 Gene

Genomics for SLC39A9 Gene

Genomic Location for SLC39A9 Gene

Start:
69,398,015 bp from pter
End:
69,462,390 bp from pter
Size:
64,376 bases
Orientation:
Plus strand

Genomic View for SLC39A9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC39A9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC39A9 Gene

Regulatory Elements for SLC39A9 Gene

Proteins for SLC39A9 Gene

  • Protein details for SLC39A9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NUM3-S39A9_HUMAN
    Recommended name:
    Zinc transporter ZIP9
    Protein Accession:
    Q9NUM3
    Secondary Accessions:
    • G3V5J8
    • Q53HN3
    • Q5MJQ0
    • Q6P2Q1
    • Q86WY2

    Protein attributes for SLC39A9 Gene

    Size:
    307 amino acids
    Molecular mass:
    32251 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC39A9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC39A9 Gene

Proteomics data for SLC39A9 Gene at MOPED

Post-translational modifications for SLC39A9 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn29 and Asn241

No data available for DME Specific Peptides for SLC39A9 Gene

Domains for SLC39A9 Gene

Gene Families for SLC39A9 Gene

Protein Domains for SLC39A9 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

S39A9_HUMAN
Family:
  • Belongs to the ZIP transporter (TC 2.A.5) family.:
    • Q9NUM3
genes like me logo Genes that share domains with SLC39A9: view

Function for SLC39A9 Gene

Molecular function for SLC39A9 Gene

UniProtKB/Swiss-Prot Function: May act as a zinc-influx transporter.

Gene Ontology (GO) - Molecular Function for SLC39A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046873 metal ion transmembrane transporter activity IEA --
genes like me logo Genes that share ontologies with SLC39A9: view

miRNA for SLC39A9 Gene

miRTarBase miRNAs that target SLC39A9

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC39A9 Gene

Localization for SLC39A9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC39A9 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC39A9 Gene COMPARTMENTS Subcellular localization image for SLC39A9 gene
Compartment Confidence
plasma membrane 3
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SLC39A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC39A9: view

Pathways for SLC39A9 Gene

SuperPathways for SLC39A9 Gene

No Data Available

Interacting Proteins for SLC39A9 Gene

Gene Ontology (GO) - Biological Process for SLC39A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006829 zinc II ion transport IEA --
GO:0030001 metal ion transport --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC39A9: view

No data available for Pathways by source for SLC39A9 Gene

Transcripts for SLC39A9 Gene

Unigene Clusters for SLC39A9 Gene

Solute carrier family 39 (zinc transporter), member 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC39A9 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b
SP1: - -
SP2: - - -
SP3: -
SP4:

Relevant External Links for SLC39A9 Gene

GeneLoc Exon Structure for
SLC39A9
ECgene alternative splicing isoforms for
SLC39A9

Expression for SLC39A9 Gene

mRNA expression in normal human tissues for SLC39A9 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SLC39A9 Gene

SOURCE GeneReport for Unigene cluster for SLC39A9 Gene Hs.432690

genes like me logo Genes that share expressions with SLC39A9: view

Orthologs for SLC39A9 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC39A9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC39A9 36
  • 99.57 (n)
  • 100 (a)
SLC39A9 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC39A9 36
  • 91.42 (n)
  • 95.11 (a)
SLC39A9 37
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC39A9 36
  • 93.16 (n)
  • 96.09 (a)
SLC39A9 37
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc39a9 36
  • 89.69 (n)
  • 93.49 (a)
Slc39a9 16
Slc39a9 37
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC39A9 37
  • 94 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SLC39A9 37
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slc39a9 36
  • 91.95 (n)
  • 95.47 (a)
chicken
(Gallus gallus)
Aves SLC39A9 36
  • 81.09 (n)
  • 90.82 (a)
SLC39A9 37
  • 85 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC39A9 37
  • 90 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.16284 36
tropical clawed frog
(Silurana tropicalis)
Amphibia slc39a9 36
  • 74.04 (n)
  • 86.14 (a)
Str.2106 36
zebrafish
(Danio rerio)
Actinopterygii slc39a9 36
  • 72.75 (n)
  • 82.08 (a)
slc39a9 37
  • 82 (a)
OneToOne
wufc56g12 36
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009188 36
  • 58.51 (n)
  • 60.34 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG2177 36
  • 57.85 (n)
  • 56.88 (a)
CG2177 37
  • 48 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea T01D3.5 36
  • 54.3 (n)
  • 52.92 (a)
T01D3.5 37
  • 39 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4940 36
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 49 (a)
OneToOne
Species with no ortholog for SLC39A9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC39A9 Gene

ENSEMBL:
Gene Tree for SLC39A9 (if available)
TreeFam:
Gene Tree for SLC39A9 (if available)

Paralogs for SLC39A9 Gene

No data available for Paralogs for SLC39A9 Gene

Variants for SLC39A9 Gene

Sequence variations from dbSNP and Humsavar for SLC39A9 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs7276 -- 69,462,226(+) GTTCA(A/G)TAGCT utr-variant-3-prime
rs1045301 -- 69,461,590(-) ACAGC(A/C)ACTCC utr-variant-3-prime, intron-variant
rs1045534 -- 69,462,323(+) TTTCC(A/C)CTTTA utr-variant-3-prime
rs1055622 -- 69,459,744(+) TCTTT(C/T)CTTTG utr-variant-3-prime, intron-variant
rs1055623 -- 69,459,780(+) CCTCT(C/T)CTCGC utr-variant-3-prime, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC39A9 Gene

Variant ID Type Subtype PubMed ID
nsv526398 CNV Loss 19592680
nsv456335 CNV Gain 19166990

Relevant External Links for SLC39A9 Gene

HapMap Linkage Disequilibrium report
SLC39A9

Disorders for SLC39A9 Gene

Relevant External Links for SLC39A9

Genetic Association Database (GAD)
SLC39A9
Human Genome Epidemiology (HuGE) Navigator
SLC39A9
genes like me logo Genes that share disorders with SLC39A9: view

No data available for UniProtKB/Swiss-Prot for SLC39A9 Gene

Publications for SLC39A9 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Polymorphisms in mitochondrial genes and prostate cancer risk. (PMID: 19064571) Wang L. … Thibodeau S.N. (Cancer Epidemiol. Biomarkers Prev. 2008) 3 49
  4. SLC39A9 (ZIP9) regulates zinc homeostasis in the secretory pathway: characterization of the ZIP subfamily I protein in vertebrate cells. (PMID: 19420709) Matsuura W. … Kambe T. (Biosci. Biotechnol. Biochem. 2009) 3
  5. Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium. (PMID: 21696611) Chambers K.F. … Lang S.H. (J. Biomed. Sci. 2011) 3

Products for SLC39A9 Gene

Sources for SLC39A9 Gene

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