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SLC39A9 Gene

protein-coding   GIFtS: 49
GCID: GC14P069865

Solute Carrier Family 39, Member 9

  Search for SLC39A9
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 39, Member 91 2     Solute Carrier Family 39 (Zinc Transporter), Member 92
Zrt- And Irt-Like Protein 92 3     Zinc Transporter SLC39A92
ZIP-92 3     Zinc Transporter ZIP92
ZIP92 3     Solute Carrier Family 39 Member 93

External Ids:    HGNC: 201821   Entrez Gene: 553342   Ensembl: ENSG000000293647   UniProtKB: Q9NUM33   

Export aliases for SLC39A9 gene to outside databases

Previous GC identifers: GC00U913003 GC14P067856 GC14P067857 GC14P068935 GC14P050033


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SLC39A9 Gene:
SLC39A9 (solute carrier family 39, member 9) is a protein-coding gene. GO annotations related to this gene include metal ion transmembrane transporter activity.

UniProtKB/Swiss-Prot: S39A9_HUMAN, Q9NUM3
Function: May act as a zinc-influx transporter (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC39A9 gene promoter:
         GR   Pbx1a   p300   C/EBPalpha   AREB6   E2F-1   E2F   HOXA5   GR-alpha   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC39A9 promoter sequence
   Search Chromatin IP Primers for SLC39A9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC39A9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24.1   Ensembl cytogenetic band:  14q24.1   HGNC cytogenetic band: 14q24.1

SLC39A9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC39A9 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P069865:  view genomic region     (about GC identifiers)

Start:
69,864,732 bp from pter      End:
69,929,107 bp from pter
Size:
64,376 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: S39A9_HUMAN, Q9NUM3 (See protein sequence)
Recommended Name: Zinc transporter ZIP9  
Size: 307 amino acids; 32251 Da
Secondary accessions: Q53HN3 Q5MJQ0 Q6P2Q1 Q86WY2
Alternative splicing: 2 isoforms:  Q9NUM3-1   Q9NUM3-2   

Explore the universe of human proteins at neXtProt for SLC39A9: NX_Q9NUM3

Explore proteomics data for SLC39A9 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn29, Asn241
  • Modification sites at PhosphoSitePlus

  • See SLC39A9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001239077.1  NP_001239079.1  NP_001239080.1  NP_001239081.1  NP_060845.2  

    ENSEMBL proteins: 
     ENSP00000452385   ENSP00000336887   ENSP00000468864   ENSP00000450639   ENSP00000451833  

    SLC39A9 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SLC39A9

     
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    Search eBioscience for ELISAs for SLC39A9 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: Zinc transporter 9
    SLC39 family of metal ion transporters

    1 InterPro protein domain:
     IPR003689 ZIP

    Graphical View of Domain Structure for InterPro Entry Q9NUM3

    ProtoNet protein and cluster: Q9NUM3

    1 Blocks protein domain: IPB003689 Zinc transporter ZIP

    UniProtKB/Swiss-Prot: S39A9_HUMAN, Q9NUM3
    Similarity: Belongs to the ZIP transporter (TC 2.A.5) family


    Find genes that share domains with SLC39A9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S39A9_HUMAN, Q9NUM3
    Function: May act as a zinc-influx transporter (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046873metal ion transmembrane transporter activity IEA--
         
    Find genes that share ontologies with SLC39A9           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC39A9
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    miRNA
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    miRTarBase miRNAs that target SLC39A9:
    hsa-mir-192-5p (MIRT026440), hsa-mir-215-5p (MIRT024680)

    Block miRNA regulation of human, mouse, rat SLC39A9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SLC39A9 (see all 91):
    hsa-miR-140-5p hsa-miR-106a hsa-miR-15a hsa-miR-218-1* hsa-miR-200a hsa-miR-138-2* hsa-miR-502-3p hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidSLC39A9 3' UTR sequence
    Inhib. RNA
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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC39A9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S39A9_HUMAN, Q9NUM3: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytosol1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SLC39A9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC39A9
    Interactions:

        Search GeneGlobe Interaction Network for SLC39A9

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006829zinc ion transport IEA--
    GO:0030001metal ion transport ----
    GO:0055085transmembrane transport ----

    Find genes that share ontologies with SLC39A9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC39A9 (S39A9)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC39A9 gene (5 alternative transcripts): 
    NM_001252148.1  NM_001252150.1  NM_001252151.1  NM_001252152.1  NM_018375.4  

    Unigene Cluster for SLC39A9:

    Solute carrier family 39 (zinc transporter), member 9
    Hs.432690  [show with all ESTs]
    Unigene Representative Sequence: NM_018375
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000556125 ENST00000555245 ENST00000538956 ENST00000556605(uc001xlf.4)
    ENST00000336643 ENST00000031146(uc021rvg.1 uc021rvh.1 uc001xle.3 uc010aqx.3)
    ENST00000554059(uc001xld.4) ENST00000555840(uc001xlg.4) ENST00000557046
    ENST00000554023
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SLC39A9 (see all 91):
    hsa-miR-140-5p hsa-miR-106a hsa-miR-15a hsa-miR-218-1* hsa-miR-200a hsa-miR-138-2* hsa-miR-502-3p hsa-miR-93
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    OriGene qPCR primer pairs and template standards for SLC39A9
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      QuantiTect SYBR Green Assays in human, mouse, rat SLC39A9
      QuantiFast Probe-based Assays in human, mouse, rat SLC39A9

    Additional mRNA sequence: 

    AK002136.1 AK025831.1 AK222547.1 AK293222.1 AK310285.1 AK311104.1 AK316381.1 AL137760.1 
    AY358687.1 AY780789.1 BC033301.1 BC062762.1 BC064383.1 FJ423549.1 

    16 DOTS entries:

    DT.100016675  DT.445513  DT.100669940  DT.100796024  DT.202590  DT.91741450  DT.91776263  DT.100641919 
    DT.100796022  DT.91976403  DT.101985095  DT.120778826  DT.95180833  DT.100807817  DT.120778701  DT.95259943 

    Selected AceView cDNA sequences (see all 332):

    BQ109223 BQ718872 F05993 CF265191 AW117655 AA700153 AI160543 N59616 
    BF221831 BU688791 BU838531 BQ430162 BU676917 AI632932 AA700480 BX432587 
    BX111771 BX387360 AW273361 BU069497 BC062762 BM791602 CR604607 BP364966 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC39A9    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b
    SP1:                          -                                   -               
    SP2:                          -                             -     -               
    SP3:                          -                                                   
    SP4:                                                                              


    ECgene alternative splicing isoforms for SLC39A9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC39A9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATGGCTGCC
    SLC39A9 Expression
    About this image

    SLC39A9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC39A9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.432690
        Custom PCR Arrays for SLC39A9
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC39A9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SLC39A9 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc39a91 , 5 solute carrier family 39 (zinc transporter), member more1, 5 89.69(n)1
    93.49(a)1
      12 (36.91 cM)5
    3281331  NM_026244.21  NP_080520.21 
     806442155 
    chicken
    (Gallus gallus)
    Aves SLC39A91 solute carrier family 39 (zinc transporter), member more 81.09(n)
    90.82(a)
      423261  NM_001007933.1  NP_001007934.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC39A96
    solute carrier family 39, member 9
    90(a)
    1 ↔ 1
    GL343318.1(441524-468698)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.162842 Xenopus laevis transcribed sequence with moderate similarity more 74.78(n)    BU915251.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc56g122 wufc56g12 76.41(n)   325159  57055177 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG21771 CG2177 57.85(n)
    56.88(a)
      43786  NM_143662.2  NP_651919.2 
    worm
    (Caenorhabditis elegans)
    Secernentea T01D3.51 T01D3.5 54.3(n)
    52.92(a)
      179862  NM_073992.4  NP_506393.1 


    ENSEMBL Gene Tree for SLC39A9 (if available)
    TreeFam Gene Tree for SLC39A9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC39A9 (see all 1195)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs37597701,2
    C,F,H--69867080(+) ACAGAT/CGTTAA 5 -- int128Minor allele frequency- C:0.48EA NA NS WA CSA 3981
    rs1868405491,2
    --69867091(+) GCGAGG/TGTCCC 5 -- int10--------
    rs1381969291,2
    --69867117(+) TGAAAA/GCACTG 5 -- int10--------
    rs1916235111,2
    --69867142(+) TGATAA/GGTCCT 5 -- int10--------
    rs1141904371,2
    C--69867310(+) AGGAGG/ACCTGA 5 -- int11Minor allele frequency- A:0.01WA 118
    rs1437673641,2
    --69867399(+) ATAGCC/TTGTGG 5 -- int10--------
    rs37597711,2
    C,F,A,H--69867489(+) TGTTGC/G/TTGTTC 5 -- int115NS EA NA WA CSA 791
    rs783171721,2
    C,F--69867753(+) GGAGAC/ATGGAT 5 -- int13Minor allele frequency- A:0.08CSA WA NA 240
    rs792314041,2
    C,F--69868050(+) CCTGCC/GCAGTA 5 -- int13Minor allele frequency- G:0.07WA NA EA 358
    rs1838656131,2
    --69868092(+) AACCAC/TATTTT 5 -- int10--------

    HapMap Linkage Disequilibrium report for SLC39A9 (69864732 - 69929107 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SLC39A9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv526398CNV Loss19592680
    nsv456335CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing SLC39A9
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC39A9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with SLC39A9           About GenesLikeMe

    Genetic Association Database (GAD): SLC39A9
    Human Genome Epidemiology (HuGE) Navigator: SLC39A9 (1 document)

    Export disorders for SLC39A9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC39A9 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with SLC39A9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Polymorphisms in mitochondrial genes and prostate cancer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (amp 2008)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    4. Stromal upregulation of lateral epithelial adhesions: gene expression analysis of signalling pathways in prostate epithelium. (PubMed id 21696611)1 Chambers K.F....Lang S.H. (J. Biomed. Sci. 2011)
    5. SLC39A9 (ZIP9) regulates zinc homeostasis in the secretory pathway: characterization of the ZIP subfamily I protein in vertebrate cells. (PubMed id 19420709)1 Matsuura W.... Kambe T. (Biosci. Biotechnol. Biochem. 2009)
    6. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55334 HGNC: 20182 AceView: SLC39A9 Ensembl:ENSG00000029364 euGenes: HUgn55334
    ECgene: SLC39A9 H-InvDB: SLC39A9

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC39A9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC39A9 gene:
    Search GeneIP for patents involving SLC39A9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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