Aliases for SLC39A8 Gene
- Solute Carrier Family 39 (Zinc Transporter), Member 8 2 3
- BCG-Induced Integral Membrane Protein In Monocyte Clone 103 Protein 3 4
- Solute Carrier Family 39 (Metal Ion Transporter), Member 8 2 3
- LIV-1 Subfamily Of ZIP Zinc Transporter 6 3 4
- Solute Carrier Family 39 Member 8 3 4
- Zrt- And Irt-Like Protein 8 3 4
- BIGM103 3 4
External Ids for SLC39A8 Gene
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]
GeneCards Summary for SLC39A8 Gene
SLC39A8 (Solute Carrier Family 39 (Zinc Transporter), Member 8) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include metal ion transmembrane transporter activity. An important paralog of this gene is SLC39A12.
UniProtKB/Swiss-Prot for SLC39A8 Gene
Acts as a zinc-influx transporter.