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SLC39A2 Gene

protein-coding   GIFtS: 54
GCID: GC14P021467

Solute Carrier Family 39 (Zinc Transporter), Member 2

  See SLC39A2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 39 (Zinc Transporter), Member 21 2     ETI-12
ZIP22 3 5     Zinc Transporter ZIP22
Solute Carrier Family 39 Member 22 3     Zinc Uptake Transporter 22
6A12 3     Eti-13
ZIP-22 3     hZIP23
Zrt- And Irt-Like Protein 22 3     

External Ids:    HGNC: 171271   Entrez Gene: 299862   Ensembl: ENSG000001657947   OMIM: 6121665   UniProtKB: Q9NP943   

Export aliases for SLC39A2 gene to outside databases

Previous GC identifers: GC14P018839 GC14P015254 GC14P019457 GC14P020537 GC14P001588


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC39A2 Gene:
This gene encodes a member of the ZIP family of metal ion transporters. The encoded protein functions as a zinc
transporter. Mutations in this gene may be associated with susceptibility to carotid artery disease. Multiple
transcript variants have been described. (provided by RefSeq, Mar 2010)

GeneCards Summary for SLC39A2 Gene:
SLC39A2 (solute carrier family 39 (zinc transporter), member 2) is a protein-coding gene. Diseases associated with SLC39A2 include artery disease, and lung cancer susceptibility. GO annotations related to this gene include zinc ion transmembrane transporter activity. An important paralog of this gene is SLC39A1.

UniProtKB/Swiss-Prot: S39A2_HUMAN, Q9NP94
Function: Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can
function in the presence of albumin. May also transport other divalent cations. May be important in contact
inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis

Gene Wiki entry for SLC39A2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC39A2 gene promoter:
         E2F-4   E2F-3a   E2F-5   POU3F2 (N-Oct-5b)   CUTL1   E2F-2   POU3F2   E2F   E2F-1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC39A2 promoter sequence
   Search Chromatin IP Primers for SLC39A2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC39A2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.1

SLC39A2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC39A2 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P021467:  view genomic region     (about GC identifiers)

Start:
21,467,414 bp from pter      End:
21,470,034 bp from pter
Size:
2,621 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: S39A2_HUMAN, Q9NP94 (See protein sequence)
Recommended Name: Zinc transporter ZIP2  
Size: 309 amino acids; 32742 Da
Miscellaneous: Zinc uptake is inhibited at pH levels below 7.0 and is stimulated at higher pH and is significantly
inhibited by Cu(2+), Co(2+) and Mn(2+) ions. Not inhibited by Fe(2+)
Secondary accessions: B2RC76 G3V5X2 Q4QQJ1 Q4V9S4 Q96JT6 Q9UD20
Alternative splicing: 2 isoforms:  Q9NP94-1   Q9NP94-2   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for SLC39A2: NX_Q9NP94

Explore proteomics data for SLC39A2 at MOPED


See SLC39A2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001243517.1  NP_055394.2  

ENSEMBL proteins: 
 ENSP00000452568   ENSP00000298681  
Reactome Protein details: Q9NP94

SLC39A2 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
SLC: Solute carriers

IUPHAR Guide to PHARMACOLOGY protein family classification: Zinc transporter 2
SLC39 family of metal ion transporters

1 InterPro protein domain:
 IPR003689 ZIP

Graphical View of Domain Structure for InterPro Entry Q9NP94

ProtoNet protein and cluster: Q9NP94

1 Blocks protein domain: IPB003689 Zinc transporter ZIP

UniProtKB/Swiss-Prot: S39A2_HUMAN, Q9NP94
Similarity: Belongs to the ZIP transporter (TC 2.A.5) family


Find genes that share domains with SLC39A2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: S39A2_HUMAN, Q9NP94
Function: Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can
function in the presence of albumin. May also transport other divalent cations. May be important in contact
inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis
Induction: Shows a dramatic induction in normal epithelial cells contact inhibition

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005385zinc ion transmembrane transporter activity IMP--
GO:0046873metal ion transmembrane transporter activity ----
     
Find genes that share ontologies with SLC39A2           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for SLC39A2:
 Increased gamma-H2AX phosphory 

     7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc39a2):
 craniofacial  embryogenesis  growth/size/body  homeostasis/metabolism  integument 
 limbs/digits/tail  liver/biliary system 

Find genes that share phenotypes with SLC39A2           About GenesLikeMe

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC39A2
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC39A2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC39A2

miRNA
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miRTarBase miRNAs that target SLC39A2:
hsa-mir-335-5p (MIRT018258)

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1 qRT-PCR Assays for microRNA that regulate SLC39A2:
hsa-miR-539
SwitchGear 3'UTR luciferase reporter plasmidSLC39A2 3' UTR sequence
Inhib. RNA
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
S39A2_HUMAN, Q9NP94: Cell membrane; Multi-pass membrane protein
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane5

Gene Ontology (GO): 4 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane TAS--
GO:0005887integral component of plasma membrane TAS10681536
GO:0016020membrane ----
GO:0016023cytoplasmic membrane-bounded vesicle IDA14612438

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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for SLC39A2 About    
See pathways by source

SuperPathContained pathways About
1Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
SLC-mediated transmembrane transport0.47
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds0.38
Transmembrane transport of small molecules0.47
2Metal ion SLC transporters
Metal ion SLC transporters
Zinc influx into cells by the SLC39 gene family0.00
Zinc transporters0.00
3Senescence and Autophagy
Senescence and Autophagy


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Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


1 BioSystems Pathway for SLC39A2
    Senescence and Autophagy

1 Reactome Pathway for SLC39A2
    Zinc influx into cells by the SLC39 gene family


    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC39A2
Interactions:

    GeneGlobe Interaction Network for SLC39A2

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

Selected Interacting proteins for SLC39A2 (Q9NP943 ENSP000002986814) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
InteractantInteraction Details
GeneCardExternal ID(s)
KCNAB1Q147223, ENSP000004199524I2D: score=1 STRING: ENSP00000419952
KCNAB2Q133033, ENSP000001642474I2D: score=1 STRING: ENSP00000164247
SLC39A1Q9NY263, ENSP000003097104I2D: score=1 STRING: ENSP00000309710
SLC39A11ENSP000002555594STRING: ENSP00000255559
RAD50ENSP000002653354STRING: ENSP00000265335
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006829zinc ion transport TAS10681536
GO:0030001metal ion transport ----
GO:0055085transmembrane transport TAS--
GO:0071577zinc ion transmembrane transport ----

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for SLC39A2 (S39A2)

1 Novoseek inferred chemical compound relationship for SLC39A2 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
zinc 60.6 12 17550612 (4), 14525987 (3), 9618566 (2), 12748861 (1) (see all 5)



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(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for SLC39A2 gene (2 alternative transcripts): 
NM_001256588.1  NM_014579.3  

Unigene Cluster for SLC39A2:

Solute carrier family 39 (zinc transporter), member 2
Hs.175783  [show with all ESTs]
Unigene Representative Sequence: NM_014579
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000554422 ENST00000298681(uc001vys.3 uc001vyr.3) ENST00000554128

miRNA
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1 qRT-PCR Assays for microRNA that regulate SLC39A2:
hsa-miR-539
SwitchGear 3'UTR luciferase reporter plasmidSLC39A2 3' UTR sequence
Inhib. RNA
Products:
     
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Clone
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Primer
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OriGene qPCR primer pairs and template standards for SLC39A2
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Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SLC39A2
  QuantiTect SYBR Green Assays in human, mouse, rat SLC39A2
  QuantiFast Probe-based Assays in human, mouse, rat SLC39A2

Additional mRNA sequence: 

AF186081.1 AK314974.1 AY029483.1 BC096723.1 BC098254.1 BC098274.1 BC110057.1 D83039.1 

1 DOTS entry:

DT.303682 

22 AceView cDNA sequences:

AI669751 AI382710 AY029483 BU727419 CR621267 AW450224 AF186081 BE673491 
NM_014579 D83039 BX369259 BX117886 AI804852 BX379871 BF437207 BM689307 
AA149204 BF222226 BP359281 BE856536 AA149203 CD708699 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for SLC39A2    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b
SP1:                    -                     
SP2:                    -                     
SP3:                                          


ECgene alternative splicing isoforms for SLC39A2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SLC39A2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
SLC39A2 Expression
About this image

SLC39A2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

SLC39A2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.175783

UniProtKB/Swiss-Prot: S39A2_HUMAN, Q9NP94
Tissue specificity: Expressed only in prostate and uterine epithelial cells

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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC39A2 gene from Selected species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Slc39a21 , 5 solute carrier family 39 (zinc transporter), member more1, 5 81.34(n)1
78.32(a)1
  14 (26.71 cM)5
2149221  NM_001039676.21  NP_001034765.21 
 518928895 
lizard
(Anolis carolinensis)
Reptilia SLC39A26
solute carrier family 39 (zinc transporter), membe...
53(a)
1 ↔ 1
GL343220.1(1565248-1575670)
tropical clawed frog
(Xenopus tropicalis)
Amphibia LOC1004960061 zinc transporter ZIP1-like 54.31(n)
48.95(a)
  100496006  XM_002934278.2  XP_002934324.1 
zebrafish
(Danio rerio)
Actinopterygii slc39a16
solute carrier family 39 (zinc transporter), membe...
36(a)
1 ↔ 1
7(14770692-14780759) ENSDARG00000058257
fruit fly
(Drosophila melanogaster)
Insecta CG43346
--
20(a)
many ↔ many
3R(11094405-11096254)
worm
(Caenorhabditis elegans)
Secernentea F31C3.46
Protein F31C3.4 (F31C3.4) mRNA, complete cds
20(a)
1 → many
I(15050797-15052420) WBGene00009286
thale cress
(Arabidopsis thaliana)
eudicotyledons ZIP21 ZIP2 40.61(n)
26.55(a)
  836071  NM_125344.2  NP_200760.1 
rice
(Oryza sativa)
Liliopsida Os01g09722001 Os01g0972200 44(n)
27.94(a)
  4326394  NM_001052075.1  NP_001045540.1 


ENSEMBL Gene Tree for SLC39A2 (if available)
TreeFam Gene Tree for SLC39A2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for SLC39A2 gene
SLC39A12  SLC39A32  
2 SIMAP similar genes for SLC39A2 using alignment to 1 protein entry:     S39A2_HUMAN:
SLC39A1    SLC39A3

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(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for SLC39A2 (see all 167)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 14 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs9439971,2
C,F,H--2464273(+) AAGCTC/TGCCCT 2 -- us2k122Minor allele frequency- T:0.12NA NS EA WA 2696
rs1834494381,2
--2464291(+) TGTGGC/TAGTTC 2 -- us2k10--------
rs1444916551,2
C--2464353(+) AAGCAA/GAAGTA 2 -- us2k10--------
rs760603741,2
C,F--2464587(+) ACCAAC/TTTAAG 2 -- us2k11Minor allele frequency- T:0.09WA 118
rs1440441181,2
--2464650(+) AAAGCA/GAACTG 2 -- us2k10--------
rs1468388671,2
C--2464686(+) TAGATA/CCTGCC 2 -- us2k10--------
rs1873410241,2
--2464695(+) CCAACA/GTGTTA 2 -- us2k10--------
rs714102551,2
C,F--2464716(+) GTGCCG/AATGAA 2 -- us2k13Minor allele frequency- A:0.06NA 124
rs1922387301,2
--2464727(+) TTTCAA/GACGCG 2 -- us2k10--------
rs1397135321,2
C--2464820(+) AGAAGC/TGTAAA 2 -- us2k10--------

HapMap Linkage Disequilibrium report for SLC39A2 (21467414 - 21470034 bp)

Structural Variations
     Database of Genomic Variants (DGV) 5 variations for SLC39A2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv470622CNV Loss18288195
nsv832740CNV Gain17160897
nsv428293CNV Gain+Loss18775914
dgv608e1CNV Complex17122850
dgv607e1CNV Complex17122850

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing SLC39A2
DNA2.0 Custom Variant and Variant Library Synthesis for SLC39A2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 612166    OMIM disorders: --

3 diseases for SLC39A2:    
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artery disease    lung cancer susceptibility    lung cancer


Find genes that share disorders with SLC39A2           About GenesLikeMe

Genetic Association Database (GAD): SLC39A2
Human Genome Epidemiology (HuGE) Navigator: SLC39A2 (5 documents)

Export disorders for SLC39A2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for SLC39A2 gene, integrated from 10 sources (see all 39):
(articles sorted by number of sources associating them with SLC39A2)
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  1. Functional expression of the human hZIP2 zinc transporter. (PubMed id 10681536)1, 2, 3 Gaither L.A. and Eide D.J. (J. Biol. Chem. 2000)
  2. Subtraction cloning of growth arrest inducible genes in normal human epithelial cells. (PubMed id 7751801)1, 2, 3 Yamaguchi S. (Kokubyo Gakkai Zasshi 1995)
  3. Genetic susceptibility to distinct bladder cancer subphenotypes. (PubMed id 19692168)1, 4 Guey L.T....Malats N. (Eur. Urol. 2010)
  4. PTEN identified as important risk factor of chronic obstructive pulmonary disease. (PubMed id 19625176)1, 4 Hosgood H.D....Lan Q. (Respir Med 2009)
  5. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1, 4 Shen M....Lan Q. (Environ. Mol. Mutagen. 2009)
  6. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1, 4 Hosgood H.D....Lan Q. (Carcinogenesis 2008)
  7. A novel Zip2 Gln/Arg/Leu codon 2 polymorphism is associated with carotid artery disease in aging. (PubMed id 18328005)1, 4 Giacconi R....Mocchegiani E. (Rejuvenation Res 2008)
  8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  9. hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands. (PubMed id 17550612)1, 9 Desouki M.M....Costello L.C. (Mol. Cancer 2007)
  10. Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2. (PubMed id 10477520)1, 9 Gong J....Li M. (Science 1999)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 29986 HGNC: 17127 AceView: SLC39A2 Ensembl:ENSG00000165794 euGenes: HUgn29986
ECgene: SLC39A2 H-InvDB: SLC39A2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for SLC39A2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SLC39A2 gene:
Search GeneIP for patents involving SLC39A2

GeneCards and IP:
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