Aliases for SLC39A14 Gene
External Ids for SLC39A14 Gene
Previous GeneCards Identifiers for SLC39A14 Gene
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SLC39A14 Gene
SLC39A14 (Solute Carrier Family 39 Member 14) is a Protein Coding gene. Among its related pathways are Metal ion SLC transporters and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include ferrous iron transmembrane transporter activity and zinc ion transmembrane transporter activity. An important paralog of this gene is SLC39A12.
UniProtKB/Swiss-Prot for SLC39A14 Gene
May mediate cellular uptake of nontransferrin-bound iron (By similarity). Broad-scope metal ion transporter with a preference for zinc uptake.