Aliases for SLC39A1 Gene
External Ids for SLC39A1 Gene
Previous Symbols for SLC39A1 Gene
This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
GeneCards Summary for SLC39A1 Gene
SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1) is a Protein Coding gene. Diseases associated with SLC39A1 include prostate cancer and breast cancer. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include receptor binding and inorganic cation transmembrane transporter activity. An important paralog of this gene is SLC39A3.
UniProtKB/Swiss-Prot for SLC39A1 Gene
Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.