Aliases for SLC38A9 Gene
Aliases for SLC38A9 Gene
External Ids for SLC38A9 Gene
- HGNC: 26907
- Entrez Gene: 153129
- Ensembl: ENSG00000177058
- OMIM: 616203
- UniProtKB: Q8NBW4
Previous GeneCards Identifiers for SLC38A9 Gene
- GC05M054958
- GC05M051895
Summaries for SLC38A9 Gene
GeneCards Summary for SLC38A9 Gene
SLC38A9 (Solute Carrier Family 38 Member 9) is a Protein Coding gene. Among its related pathways are mTOR signaling pathway (KEGG). Gene Ontology (GO) annotations related to this gene include amino acid transmembrane transporter activity.
UniProtKB/Swiss-Prot for SLC38A9 Gene
-
Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).
Additional gene information for SLC38A9 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC38A9 Gene
Genomics for SLC38A9 Gene
GeneHancer (GH) Regulatory Elements for SLC38A9 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH05I055711 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 560.6 | +60.8 | 60769 | 2 | HDGF PKNOX1 SMAD1 ARID4B SIN3A DMAP1 YY1 SLC30A9 POLR2B ZNF766 | SLC38A9 DDX4 IL31RA DHX29 MTREX RNA5SP183 GC05P055648 | |
GH05I055692 | Promoter | 0.9 | EPDnew | 550.2 | +80.4 | 80431 | 0.1 | FOXA2 NFIA FEZF1 RAD21 PRDM6 HNF1A BCL6 HNF4A | SLC38A9 DDX4 GC05P055648 | |
GH05I055697 | Promoter | 0.5 | EPDnew | 550.2 | +75.3 | 75276 | 0.1 | SLC38A9 DDX4 GC05P055648 | ||
GH05I055305 | Promoter/Enhancer | 2.1 | EPDnew Ensembl ENCODE | 22.2 | +465.7 | 465678 | 4.6 | HDGF PKNOX1 SMAD1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 IRF4 | MTREX DHX29 SLC38A9 ENSG00000264281 CCNO RNF138P1 GC05P055257 | |
GH05I055463 | Enhancer | 0.9 | FANTOM5 | 32.7 | +309.1 | 309091 | 0.3 | ZNF493 ZNF529 ZFP64 MZF1 ZNF155 ZNF121 ZNF23 ZNF354C ZNF138 KLF7 | DHX29 MTREX SLC38A9 RNF138P1 GPX8 FLJ31104 ENSG00000264281 LOC100419851 ENSG00000279883 GC05M055421 |
- Top Transcription factor binding sites by QIAGEN in the SLC38A9 gene promoter:
Regulatory Element Products
Genomic Locations for SLC38A9 Gene
- chr5:55,625,845-55,773,194
- (GRCh38/hg38)
- Size:
- 147,350 bases
- Orientation:
- Minus strand
- chr5:54,921,673-55,069,022
- (GRCh37/hg19)
Genomic View for SLC38A9 Gene
- Cytogenetic band:
-
- 5q11.2 by Ensembl
- 5q11.2 by Entrez Gene
- 5q11.2 by HGNC


RefSeq DNA sequence for SLC38A9 Gene
Proteins for SLC38A9 Gene
-
Protein details for SLC38A9 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NBW4-S38A9_HUMAN
- Recommended name:
- Sodium-coupled neutral amino acid transporter 9
- Protein Accession:
- Q8NBW4
- A0A0A8K8P2
- B3KXV1
- B7Z7D0
- Q0P5S0
- Q6MZJ8
Protein attributes for SLC38A9 Gene
- Size:
- 561 amino acids
- Molecular mass:
- 63776 Da
- Quaternary structure:
-
- Associated component of the Ragulator complex (composed of LAMTOR1, LAMTOR2, LAMTOR3, LAMTOR4 and LAMTOR5). Associated component of the Rag GTPases heterodimers (composed of RRAGA, RRAGB, RRAGC and RRAGD).
- SequenceCaution:
-
- Sequence=BAQ19756.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for SLC38A9 Gene
Post-translational modifications for SLC38A9 Gene
- Glycosylated.
- Ubiquitination at isoforms=237
- Glycosylation at isoforms=2, 3, 4239, isoforms=2, 3, 4248, posLast=266266, and posLast=274274
Other Protein References for SLC38A9 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001245215.1
- NP_001245216.1
- NP_001269358.1
- NP_001336311.1
- NP_001336312.1
- NP_001336313.1
- NP_001336314.1
- NP_775785.2
- XP_006714600.1
- XP_006714601.1
- XP_006714602.1
- XP_011541475.1
- XP_011541476.1
- XP_011541478.1
- XP_011541479.1
- XP_011541480.1
- XP_011541482.1
- XP_011541484.1
- XP_011541485.1
- XP_011541486.1
- XP_016864566.1
- XP_016864567.1
- XP_016864568.1
- XP_016864569.1
- XP_016864570.1
- XP_016864571.1
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for SLC38A9
- Novus Biologicals Antibodies for SLC38A9
-
Abcam antibodies for SLC38A9
- Invitrogen Antibodies for SLC38A9
- antibodies-online: Search results for 4 available SLC38A9 Antibodies ranked by validation data
- Compare Top SLC38A9 Antibodies
-
Quality Products:
- GeneTex SLC38A9 antibody for SLC38A9
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SLC38A9
- Origene Custom Protein Services for SLC38A9
- Novus Biologicals proteins for SLC38A9
- antibodies-online: Search results for 4 available SLC38A9 Proteins ranked by validation data
- Compare Top SLC38A9 Proteins
-
Quality Products:
- Search GeneTex for Proteins for SLC38A9
Assay Products
No data available for DME Specific Peptides for SLC38A9 Gene
Domains & Families for SLC38A9 Gene
Gene Families for SLC38A9 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
- Transporters
Protein Domains for SLC38A9 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for SLC38A9 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8NBW4UniProtKB/Swiss-Prot:
S38A9_HUMAN :- The cytosolic N-terminus part of the protein mediates interaction with the Ragulator complex and the Rag GTPases heterodimers.
- Belongs to the amino acid/polyamine transporter 2 family. SLC38A9 subfamily.
- Domain:
-
- The cytosolic N-terminus part of the protein mediates interaction with the Ragulator complex and the Rag GTPases heterodimers.
- Family:
-
- Belongs to the amino acid/polyamine transporter 2 family. SLC38A9 subfamily.
Function for SLC38A9 Gene
Molecular function for SLC38A9 Gene
- UniProtKB/Swiss-Prot Function:
- Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acids. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids (PubMed:25561175, PubMed:25567906). Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids, suggesting that it acts as an amino acid sensor instead (PubMed:25561175, PubMed:25567906). The high concentration of arginine in lysosomes suggests that it acts as an arginine sensor (PubMed:25567906).
Phenotypes From GWAS Catalog for SLC38A9 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 25561175 |
GO:0015171 | amino acid transmembrane transporter activity | IDA,TAS | -- |
Phenotypes for SLC38A9 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for SLC38A9
-
-
ViGene Biosciences lentiviral particle packaged cDNA for SLC38A9 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SLC38A9 gene
- Search ViGene Biosciences for SLC38A9
CRISPR Products
-
OriGene CRISPR knockouts for SLC38A9
- genomics-online: gRNA clones - Search results for 110 available SLC38A9 gene related products
- Overview of 110 available SLC38A9 gene related products
- Applied Biological Materials CRISPR for SLC38A9
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SLC38A9
- GenScript: Design CRISPR guide RNA sequences for SLC38A9
miRNA for SLC38A9 Gene
- miRTarBase miRNAs that target SLC38A9
-
- hsa-mir-3194-5p (MIRT487295)
- hsa-mir-4755-3p (MIRT487296)
- hsa-mir-3607-3p (MIRT487297)
- hsa-mir-1972 (MIRT487298)
- hsa-mir-548ay-3p (MIRT487299)
- hsa-mir-548at-3p (MIRT487300)
- hsa-mir-548as-3p (MIRT487301)
- hsa-mir-548t-3p (MIRT487302)
- hsa-mir-548ap-3p (MIRT487303)
- hsa-mir-548aa (MIRT487304)
- hsa-mir-8086 (MIRT512692)
- hsa-mir-4474-5p (MIRT512693)
- hsa-mir-372-5p (MIRT512694)
- hsa-mir-371a-5p (MIRT512695)
- hsa-mir-616-5p (MIRT512696)
- hsa-mir-373-5p (MIRT512697)
- hsa-mir-371b-5p (MIRT512698)
- hsa-mir-3934-5p (MIRT512699)
- hsa-mir-764 (MIRT512700)
- hsa-mir-125a-3p (MIRT512701)
- hsa-mir-4659b-3p (MIRT534201)
- hsa-mir-4659a-3p (MIRT534202)
- hsa-mir-6875-3p (MIRT534203)
- hsa-mir-4775 (MIRT534204)
- hsa-mir-4778-3p (MIRT534205)
- hsa-mir-24-2-5p (MIRT653522)
- hsa-mir-24-1-5p (MIRT653523)
- hsa-mir-1911-5p (MIRT653524)
- hsa-mir-1976 (MIRT653525)
- hsa-mir-3653-5p (MIRT653526)
- hsa-mir-6747-3p (MIRT653527)
- hsa-mir-6727-3p (MIRT653528)
- hsa-mir-4722-3p (MIRT653529)
- hsa-mir-145-3p (MIRT653530)
- hsa-mir-488-5p (MIRT653531)
- hsa-mir-4661-3p (MIRT653532)
- hsa-mir-129-5p (MIRT653533)
- hsa-mir-5010-3p (MIRT653534)
- hsa-mir-2113 (MIRT653535)
- hsa-mir-8063 (MIRT653536)
- hsa-mir-501-5p (MIRT653537)
- hsa-mir-500a-5p (MIRT653538)
- hsa-mir-551b-5p (MIRT653539)
- hsa-mir-3675-3p (MIRT653540)
- hsa-mir-605-5p (MIRT653541)
- hsa-mir-106a-3p (MIRT671488)
- hsa-mir-4430 (MIRT671489)
- hsa-mir-3652 (MIRT671490)
- hsa-mir-564 (MIRT671491)
- hsa-mir-122-5p (MIRT671492)
- hsa-mir-504-3p (MIRT671493)
- hsa-mir-3135b (MIRT671494)
- hsa-mir-4695-3p (MIRT671495)
- hsa-mir-4772-3p (MIRT671496)
- hsa-mir-6787-3p (MIRT671497)
- hsa-mir-1304-3p (MIRT671498)
- hsa-mir-6736-3p (MIRT671499)
- hsa-mir-6890-3p (MIRT671500)
- hsa-mir-183-5p (MIRT671501)
- hsa-mir-454-3p (MIRT671502)
- hsa-mir-4295 (MIRT671503)
- hsa-mir-3666 (MIRT671504)
- hsa-mir-301b-3p (MIRT671505)
- hsa-mir-301a-3p (MIRT671506)
- hsa-mir-130b-3p (MIRT671507)
- hsa-mir-130a-3p (MIRT671508)
- hsa-mir-5197-5p (MIRT671509)
- hsa-mir-1264 (MIRT761734)
- hsa-mir-330-3p (MIRT765631)
- hsa-mir-3654 (MIRT766409)
- hsa-mir-4520-3p (MIRT769969)
- hsa-mir-4638-3p (MIRT770515)
- hsa-mir-519d-5p (MIRT773734)
- hsa-mir-6835-3p (MIRT780035)
miRNA Products
- Search ViGene Biosciences for SLC38A9
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SLC38A9
- Browse OriGene Inhibitory RNA Products For SLC38A9
- genomics-online: shRNA clones - Search results for 110 available SLC38A9 gene related products
- Overview of 110 available SLC38A9 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SLC38A9 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SLC38A9
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SLC38A9
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for SLC38A9
- Applied Biological Materials Clones for SLC38A9
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for SLC38A9
-
ViGene Biosciences adenoviral particle packaged cDNA for SLC38A9 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for SLC38A9 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for SLC38A9 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC38A9 Gene
Localization for SLC38A9 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SLC38A9 Gene
- Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein.
- Nucleoplasm (2)
- Vesicles (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005654 | nucleoplasm | IDA | -- |
GO:0005764 | lysosome | IEA,IDA | 25561175 |
GO:0005765 | lysosomal membrane | TAS | -- |
GO:0005768 | endosome | IEA | -- |
GO:0005770 | late endosome | IDA | 25561175 |
Pathways & Interactions for SLC38A9 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | mTOR signaling pathway (KEGG) |
Pathways by source for SLC38A9 Gene
1 KEGG pathway for SLC38A9 Gene
Interacting Proteins for SLC38A9 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003333 | amino acid transmembrane transport | IDA | 25567906 |
GO:0006810 | transport | IEA | -- |
GO:0006865 | amino acid transport | IEA | -- |
GO:0007050 | cell cycle arrest | TAS | -- |
GO:0016241 | regulation of macroautophagy | TAS | -- |
No data available for SIGNOR curated interactions for SLC38A9 Gene
Transcripts for SLC38A9 Gene
mRNA/cDNA for SLC38A9 Gene
- (26) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (63) Selected AceView cDNA sequences:
- (26) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SLC38A9 Gene
- Solute carrier family 38, member 9:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for SLC38A9
- genomics-online: gRNA clones - Search results for 110 available SLC38A9 gene related products
- Overview of 110 available SLC38A9 gene related products
- Applied Biological Materials CRISPR for SLC38A9
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for SLC38A9
- GenScript: Design CRISPR guide RNA sequences for SLC38A9
miRNA Products
- Search ViGene Biosciences for SLC38A9
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for SLC38A9
- Browse OriGene Inhibitory RNA Products For SLC38A9
- genomics-online: shRNA clones - Search results for 110 available SLC38A9 gene related products
- Overview of 110 available SLC38A9 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for SLC38A9 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for SLC38A9
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for SLC38A9
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for SLC38A9
- Applied Biological Materials Clones for SLC38A9
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | |||||||||||||||||||||
SP2: | |||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||
SP4: | - | - |
Expression for SLC38A9 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- nGnG Amacrine Cells Inner Nuclear Layer
-
Neurons
- nGnG Amacrine Cells Inner Nuclear Layer
-
Placenta (Extraembryonic Tissues)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SLC38A9 Gene
NURSA nuclear receptor signaling pathways regulating expression of SLC38A9 Gene:
SLC38A9SOURCE GeneReport for Unigene cluster for SLC38A9 Gene:
Hs.745105Primer Products
-
OriGene qPCR primer pairs for SLC38A9
- genomics-online: primer clones - Search results for 110 available SLC38A9 gene related products
- Overview of 110 available SLC38A9 gene related products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC38A9 Gene
Orthologs for SLC38A9 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | SLC38A9 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | SLC38A9 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | SLC38A9 33 34 |
|
||
mouse (Mus musculus) |
Mammalia | Slc38a9 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Slc38a9 33 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | SLC38A9 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | SLC38A9 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | SLC38A9 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | SLC38A9 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | slc38a9 33 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.2883 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | slc38a9 33 34 |
|
||
worm (Caenorhabditis elegans) |
Secernentea | F13H10.3 33 34 |
|
||
sea squirt (Ciona savignyi) |
Ascidiacea | CSA.10819 34 |
|
OneToOne |
- Species where no ortholog for SLC38A9 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for SLC38A9 Gene
(1) SIMAP similar genes for SLC38A9 Gene using alignment to 12 proteins:
No data available for Paralogs for SLC38A9 Gene
Variants for SLC38A9 Gene
SNP ID | Clin | Chr 05 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000016038 | -- | 55,707,723(-) | T/C | genic_upstream_transcript_variant, intron_variant | |
rs1000063940 | -- | 55,694,789(-) | T/C | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000146290 | -- | 55,694,720(-) | C/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
rs1000147353 | -- | 55,673,778(-) | C/T | intron_variant | |
rs1000180417 | -- | 55,673,450(-) | T/C | intron_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2759343 | CNV | gain | 17122850 |
esv3424207 | CNV | insertion | 20981092 |
esv3447394 | CNV | duplication | 20981092 |
nsv1109697 | CNV | deletion | 24896259 |
nsv1123947 | CNV | deletion | 24896259 |
nsv329478 | CNV | deletion | 16902084 |
nsv507253 | OTHER | sequence alteration | 20534489 |
nsv507254 | OTHER | sequence alteration | 20534489 |
nsv830304 | CNV | gain+loss | 17160897 |
nsv830305 | CNV | loss | 17160897 |
nsv830306 | CNV | gain | 17160897 |
Additional Variant Information for SLC38A9 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SLC38A9
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC38A9 Gene
Disorders for SLC38A9 Gene
Additional Disease Information for SLC38A9
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for SLC38A9 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC38A9 Gene
Publications for SLC38A9 Gene
- SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. (PMID: 25561175) Rebsamen M … Superti-Furga G (Nature 2015) 2 3 4 58
- Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. (PMID: 25567906) Wang S … Sabatini DM (Science (New York, N.Y.) 2015) 2 3 4 58
- Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PMID: 20881960) Lango Allen H … Hirschhorn JN (Nature 2010) 3 44 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
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