SLC38A9 Gene
protein-coding GIFtS: 41
GCID: GC05M054958
|
|
solute carrier family 38, member 9
| |
Aliases
for SLC38A9 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Solute Carrier Family 38, Member 91 2 | | FLJ907091 | | Putative Sodium-Coupled Neutral Amino Acid Transporter 92 |
Export aliases for SLC38A9 gene to outside databasesPrevious GC identifer: GC05M051895 |
Summaries
for SLC38A9 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: S38A9_HUMAN, Q8NBW4Function: Putative sodium-dependent amino acid/proton antiporter (By similarity)
|
Genomic Views
for SLC38A9 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_006713.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SLC38A9 gene promoter:
AhR COUP-TF1 COUP FOXO3 HNF-4alpha2 HNF-4alpha1 FOXO3b COUP-TF NRF-2 FOXO3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for SLC38A9
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC38A9 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q11.2 Ensembl cytogenetic band: 5q11.2 HGNC cytogenetic band: 5q11.2SLC38A9 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M054958: view genomic region
(about GC identifiers)
Start:
|
54,921,673 bp from pter |
End:
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55,069,022 bp from pter |
Size:
|
147,350 bases |
Orientation:
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minus strand |
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Proteins
for SLC38A9 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: S38A9_HUMAN, Q8NBW4 (See
protein sequence)Recommended Name: Putative sodium-coupled neutral amino acid transporter 9 Size: 561 amino acids; 63776 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: B3KXV1 B7Z7D0 Q0P5S0 Q6MZJ8Alternative splicing: 4 isoforms: Q8NBW4-1 Q8NBW4-2 Q8NBW4-3 Q8NBW4-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SLC38A9: NX_Q8NBW4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NBW4
SLC38A9 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001245215.1 NP_001245216.1 NP_775785.2
ENSEMBL proteins: ENSP00000427707 ENSP00000380074 ENSP00000420934 ENSP00000426925 ENSP00000427335 ENSP00000423219 ENSP00000426413 ENSP00000424918 ENSP00000425055 ENSP00000427624 ENSP00000422843 ENSP00000424271 ENSP00000425259 ENSP00000420950 ENSP00000425842 ENSP00000316596 ENSP00000397429 ENSP00000437771
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
SLC38A9 for ontologies About GeneDecksing
SLC38A9 Antibody Products:
Assay Products for SLC38A9: |
Protein
Domains /
Families
for SLC38A9 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SLC38A9 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8NBW4ProtoNet protein and cluster: Q8NBW4 UniProtKB/Swiss-Prot: S38A9_HUMAN, Q8NBW4Similarity: Belongs to the amino acid/polyamine transporter 2 family |
Function
for SLC38A9 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: S38A9_HUMAN, Q8NBW4Function: Putative sodium-dependent amino acid/proton antiporter (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC38A9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC38A9
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC38A9 |
2 GenomeRNAi human phenotypes for SLC38A9:
|
Pathways & Interactions
for SLC38A9 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC38A9
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006814 | sodium ion transport |
IEA | -- | | GO:0006865 | amino acid transport |
IEA | -- |
SLC38A9 for ontologies About GeneDecksing
|
Drugs & Compounds
for SLC38A9 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SLC38A9
1 HMDB Compound for SLC38A9 About this table
Search CenterWatch for drugs/clinical trials and news about SLC38A9 / S38A9
|
Transcripts
for SLC38A9 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SLC38A9 gene (3 alternative transcripts): NM_001258286.1 NM_001258287.1 NM_173514.3 Unigene Cluster for SLC38A9: Solute carrier family 38, member 9 Hs.649685 [show with all ESTs]Unigene Representative Sequence: NM_00125828618/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27): ENST00000515159 ENST00000505708(uc003jqe.2) ENST00000396865(uc003jqf.2 uc010ivy.2)
ENST00000515629(uc003jqd.2 uc010ivx.2) ENST00000508124 ENST00000512595
ENST00000511233 ENST00000515754 ENST00000524030 ENST00000512208 ENST00000524154
ENST00000507447 ENST00000514806 ENST00000503817 ENST00000503891 ENST00000502247
ENST00000513993 ENST00000505563
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC38A9 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC38A9
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SLC38A9 (NM_173514) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC38A9 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC38A9 |
Additional cDNA sequence: AK057666.1 AK075190.1 AK122957.1 AK127988.1 AK301850.1 BC036232.1 BC045589.1 BC066891.1 BC101361.1 BC101362.2 NR_047649.1 NR_047650.1 13 DOTS entries: DT.95150773 DT.91745257 DT.100000911 DT.100719456 DT.40113778 DT.40124443 DT.97786686 DT.100705024 DT.100754703 DT.40197539 DT.40289376 DT.99970630 DT.40221334 24/63 AceView cDNA sequences (see all 63): BU632379 AI418728 AK127988 AA760716 BC036232 CR608660 AW024248 AW449801 AK122957 BX101969 AW026144 AK075190 CK819547 AI149244 BC045589 AI580489 BC066891 BG054799 CB988696 BM802069 CB961543 AK057666 BG723739 AA725807
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC38A9 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SLC38A9
|
Expression
for SLC38A9 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SLC38A9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See SLC38A9 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC38A9
SOURCE GeneReport for Unigene cluster: Hs.649685
SABiosciences Custom PCR Arrays for SLC38A9
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC38A9
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC38A9 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC38A9 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC38A9 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC38A9 |
Orthologs
for SLC38A9 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SLC38A9 gene from 7/20 species (see all 20) About this table
ENSEMBL Gene Tree for SLC38A9 (if available)
TreeFam Gene Tree for SLC38A9 (if available) |
Paralogs
for SLC38A9 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SLC38A9 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SLC38A9 (54921673 - 55069022 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for SLC38A9
3 CNVs: 6403 4445 2578 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC38A9 |
|
Disorders
/ Diseases
for SLC38A9 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for SLC38A9 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SLC38A9 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SLC38A9) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Hundreds of variants clustered in genomic loci and bi ological pathways affect human height. (PubMed id 20881960)1 Lango Allen H....Hirschhorn J.N. (2010)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1 Otsuki T....Isogai T. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for SLC38A9 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SLC38A9 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SLC38A9 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SLC38A9 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SLC38A9 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SLC38A9 gene:
Search GeneIP for patents involving SLC38A9
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SLC38A9 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SLC38A9 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC38A9 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC38A9 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SLC38A9 | | OriGene 3'-UTR Clone for SLC38A9 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC38A9 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC38A9 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 | | | SLC38A9 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC38A9 |
|  |  |  | | | | Search ThermoFisher Antibodies for SLC38A9 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC38A9 |
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