Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SLC38A11 Gene

Aliases for SLC38A11 Gene

  • Solute Carrier Family 38, Member 11 2 3
  • Solute Carrier Family 38 Member 11 3 4
  • AVT2 3 4
  • Putative Sodium-Coupled Neutral Amino Acid Transporter 11 3

External Ids for SLC38A11 Gene

Summaries for SLC38A11 Gene

GeneCards Summary for SLC38A11 Gene

SLC38A11 (Solute Carrier Family 38, Member 11) is a Protein Coding gene. An important paralog of this gene is SLC38A1.

UniProtKB/Swiss-Prot for SLC38A11 Gene

  • Putative sodium-dependent amino acid/proton antiporter.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC38A11 Gene

Genomics for SLC38A11 Gene

Genomic Location for SLC38A11 Gene

Start:
164,896,186 bp from pter
End:
164,955,525 bp from pter
Size:
59,340 bases
Orientation:
Minus strand

Genomic View for SLC38A11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC38A11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC38A11 Gene

Regulatory Elements for SLC38A11 Gene

Proteins for SLC38A11 Gene

  • Protein details for SLC38A11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q08AI6-S38AB_HUMAN
    Recommended name:
    Putative sodium-coupled neutral amino acid transporter 11
    Protein Accession:
    Q08AI6
    Secondary Accessions:
    • B4DF99
    • Q8N887

    Protein attributes for SLC38A11 Gene

    Size:
    406 amino acids
    Molecular mass:
    44825 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC38A11 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC38A11 Gene

Proteomics data for SLC38A11 Gene at MOPED

Post-translational modifications for SLC38A11 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn44 and Asn275

Other Protein References for SLC38A11 Gene

No data available for DME Specific Peptides for SLC38A11 Gene

Domains for SLC38A11 Gene

Gene Families for SLC38A11 Gene

HGNC:
  • SLC :Solute carriers
IUPHAR :

Protein Domains for SLC38A11 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC38A11 Gene

Graphical View of Domain Structure for InterPro Entry

Q08AI6

UniProtKB/Swiss-Prot:

S38AB_HUMAN
Family:
  • Belongs to the amino acid/polyamine transporter 2 family.:
    • Q08AI6
genes like me logo Genes that share domains with SLC38A11: view

Function for SLC38A11 Gene

Molecular function for SLC38A11 Gene

UniProtKB/Swiss-Prot Function: Putative sodium-dependent amino acid/proton antiporter.

Gene Ontology (GO) - Molecular Function for SLC38A11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015171 amino acid transmembrane transporter activity IBA --
genes like me logo Genes that share ontologies with SLC38A11: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC38A11 Gene

Localization for SLC38A11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC38A11 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC38A11 Gene COMPARTMENTS Subcellular localization image for SLC38A11 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for SLC38A11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC38A11: view

Pathways for SLC38A11 Gene

SuperPathways for SLC38A11 Gene

No Data Available

Interacting Proteins for SLC38A11 Gene

Gene Ontology (GO) - Biological Process for SLC38A11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003333 amino acid transmembrane transport IBA --
GO:0006814 sodium ion transport IEA --
GO:0006865 amino acid transport --
genes like me logo Genes that share ontologies with SLC38A11: view

No data available for Pathways by source for SLC38A11 Gene

Compounds for SLC38A11 Gene

(1) HMDB Compounds for SLC38A11 Gene

Compound Synonyms Cas Number PubMed IDs
Sodium
  • Sodium
7440-23-5
genes like me logo Genes that share compounds with SLC38A11: view

Transcripts for SLC38A11 Gene

Unigene Clusters for SLC38A11 Gene

Solute carrier family 38, member 11:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC38A11 Gene

No ASD Table

Relevant External Links for SLC38A11 Gene

GeneLoc Exon Structure for
SLC38A11
ECgene alternative splicing isoforms for
SLC38A11

Expression for SLC38A11 Gene

mRNA expression in normal human tissues for SLC38A11 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for SLC38A11 Gene Hs.658702

genes like me logo Genes that share expressions with SLC38A11: view

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SLC38A11 Gene

Orthologs for SLC38A11 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLC38A11 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC38A11 35
  • 99.51 (n)
  • 99.75 (a)
SLC38A11 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC38A11 35
  • 87.85 (n)
  • 88.67 (a)
SLC38A11 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC38A11 35
  • 88.1 (n)
  • 86.95 (a)
SLC38A11 36
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc38a11 35
  • 84.56 (n)
  • 85.06 (a)
Slc38a11 16
Slc38a11 36
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 63 (a)
OneToMany
-- 36
  • 70 (a)
OneToMany
-- 36
  • 66 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SLC38A11 36
  • 67 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slc38a11 35
  • 82.1 (n)
  • 83 (a)
chicken
(Gallus gallus)
Aves SLC38A11 35
  • 72.27 (n)
  • 70.28 (a)
SLC38A11 36
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC38A11 36
  • 54 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc38a11 35
  • 66.32 (n)
  • 62.69 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100536170 35
  • 61.2 (n)
  • 60.35 (a)
slc38a11 36
  • 53 (a)
OneToMany
slc38a11 36
  • 53 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005983 35
  • 47.19 (n)
  • 39.48 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13743 35
  • 45.66 (n)
  • 38.54 (a)
CG13743 36
  • 28 (a)
OneToOne
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR671W 35
  • 44.32 (n)
  • 32.68 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes AVT2 35
  • 45.45 (n)
  • 33.61 (a)
AVT2 36
  • 24 (a)
OneToMany
AVT2 38
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C02277g 35
  • 43.87 (n)
  • 28.49 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU01481 35
  • 47.48 (n)
  • 36.98 (a)
Species with no ortholog for SLC38A11:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC38A11 Gene

ENSEMBL:
Gene Tree for SLC38A11 (if available)
TreeFam:
Gene Tree for SLC38A11 (if available)

Paralogs for SLC38A11 Gene

Paralogs for SLC38A11 Gene

genes like me logo Genes that share paralogs with SLC38A11: view

Variants for SLC38A11 Gene

Sequence variations from dbSNP and Humsavar for SLC38A11 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
VAR_039981 -

Structural Variations from Database of Genomic Variants (DGV) for SLC38A11 Gene

Variant ID Type Subtype PubMed ID
nsv834444 CNV Gain 17160897

Relevant External Links for SLC38A11 Gene

HapMap Linkage Disequilibrium report
SLC38A11

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC38A11 Gene

Disorders for SLC38A11 Gene

Relevant External Links for SLC38A11

Genetic Association Database (GAD)
SLC38A11
Human Genome Epidemiology (HuGE) Navigator
SLC38A11
genes like me logo Genes that share disorders with SLC38A11: view

No data available for UniProtKB/Swiss-Prot for SLC38A11 Gene

Publications for SLC38A11 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects. (PMID: 23506890) SchiAPth H.B. … Fredriksson R. (Mol. Aspects Med. 2013) 3
  4. Web-based, participant-driven studies yield novel genetic associations for common traits. (PMID: 20585627) Eriksson N. … Mountain J. (PLoS Genet. 2010) 48
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for SLC38A11 Gene

Sources for SLC38A11 Gene

Back to Top

Content