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Aliases for SLC37A1 Gene

Aliases for SLC37A1 Gene

  • Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 1 2 3
  • G3PP 3 4 6
  • Solute Carrier Family 37 (Glycerol-3-Phosphate Transporter), Member 1 2 3
  • Glycerol-3-Phosphate Permease 3 4
  • G-3-P Transporter 3 4
  • G-3-P Permease 3 4
  • Solute Carrier Family 37 Member 1 4
  • Glycerol-3-Phosphate Transporter 3

External Ids for SLC37A1 Gene

Summaries for SLC37A1 Gene

Entrez Gene Summary for SLC37A1 Gene

  • SLC37A1, a member of the sugar-phosphate transport family, transports glycerol-3-phosphate (G3P) between cellular compartments for its utilization in several compartment-specific biochemical pathways.[supplied by OMIM, Jul 2004]

GeneCards Summary for SLC37A1 Gene

SLC37A1 (Solute Carrier Family 37 (Glucose-6-Phosphate Transporter), Member 1) is a Protein Coding gene. Diseases associated with SLC37A1 include glycerol kinase deficiency. GO annotations related to this gene include transporter activity. An important paralog of this gene is SLC37A2.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC37A1 Gene

Genomics for SLC37A1 Gene

Genomic Location for SLC37A1 Gene

Start:
42,496,008 bp from pter
End:
42,581,440 bp from pter
Size:
85,433 bases
Orientation:
Plus strand

Genomic View for SLC37A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC37A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC37A1 Gene

Regulatory Elements for SLC37A1 Gene

Proteins for SLC37A1 Gene

  • Protein details for SLC37A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P57057-GLPT_HUMAN
    Recommended name:
    Glycerol-3-phosphate transporter
    Protein Accession:
    P57057
    Secondary Accessions:
    • D3DSJ7
    • Q9HAQ1

    Protein attributes for SLC37A1 Gene

    Size:
    533 amino acids
    Molecular mass:
    57648 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC37A1 Gene

Proteomics data for SLC37A1 Gene at MOPED

Post-translational modifications for SLC37A1 Gene

No Post-translational modifications

Other Protein References for SLC37A1 Gene

No data available for DME Specific Peptides for SLC37A1 Gene

Domains for SLC37A1 Gene

Gene Families for SLC37A1 Gene

Protein Domains for SLC37A1 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC37A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P57057

UniProtKB/Swiss-Prot:

GLPT_HUMAN
Family:
  • Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.:
    • P57057
genes like me logo Genes that share domains with SLC37A1: view

Function for SLC37A1 Gene

Gene Ontology (GO) - Molecular Function for SLC37A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity IEA --
genes like me logo Genes that share ontologies with SLC37A1: view

miRNA for SLC37A1 Gene

miRTarBase miRNAs that target SLC37A1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC37A1 Gene

Localization for SLC37A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC37A1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC37A1 Gene COMPARTMENTS Subcellular localization image for SLC37A1 gene
Compartment Confidence
plasma membrane 3
cytosol 1
endoplasmic reticulum 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SLC37A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IDA 19946888
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC37A1: view

Pathways for SLC37A1 Gene

SuperPathways for SLC37A1 Gene

No Data Available

Interacting Proteins for SLC37A1 Gene

Gene Ontology (GO) - Biological Process for SLC37A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008643 carbohydrate transport IEA --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC37A1: view

No data available for Pathways by source for SLC37A1 Gene

Compounds for SLC37A1 Gene

(1) Novoseek inferred chemical compound relationships for SLC37A1 Gene

Compound -log(P) Hits PubMed IDs
glycerol 3-phosphate 90.1 17
genes like me logo Genes that share compounds with SLC37A1: view

Transcripts for SLC37A1 Gene

Unigene Clusters for SLC37A1 Gene

Solute carrier family 37 (glycerol-3-phosphate transporter), member 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC37A1 Gene

No ASD Table

Relevant External Links for SLC37A1 Gene

GeneLoc Exon Structure for
SLC37A1
ECgene alternative splicing isoforms for
SLC37A1

Expression for SLC37A1 Gene

mRNA expression in normal human tissues for SLC37A1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SLC37A1 Gene

SOURCE GeneReport for Unigene cluster for SLC37A1 Gene Hs.547009

mRNA Expression by UniProt/SwissProt for SLC37A1 Gene

P57057-GLPT_HUMAN
Tissue specificity: Expressed in numerous tissues, with highest expression in kidney, bone marrow, spleen, liver, small intestine, as well as in fetal brain, liver and spleen
genes like me logo Genes that share expressions with SLC37A1: view

No data available for mRNA differential expression in normal tissues for SLC37A1 Gene

Orthologs for SLC37A1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC37A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC37A1 35
  • 99.44 (n)
  • 99.44 (a)
SLC37A1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLC37A1 35
  • 84.74 (n)
  • 87.24 (a)
SLC37A1 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC37A1 35
  • 86.38 (n)
  • 88.7 (a)
SLC37A1 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc37a1 35
  • 83.24 (n)
  • 87.01 (a)
Slc37a1 16
Slc37a1 36
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC37A1 36
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SLC37A1 36
  • 80 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slc37a1 35
  • 83.05 (n)
  • 86.87 (a)
chicken
(Gallus gallus)
Aves SLC37A1 35
  • 70.15 (n)
  • 75.9 (a)
SLC37A1 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC37A1 36
  • 76 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii slc37a1 35
  • 65.33 (n)
  • 68.97 (a)
slc37a1 36
  • 67 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta MFS16 36
  • 41 (a)
OneToMany
CG10069 37
  • 44 (a)
worm
(Caenorhabditis elegans)
Secernentea T10C6.6a 37
  • 30 (a)
T10C6.6b 37
  • 31 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT4G17550 35
  • 50.43 (n)
  • 45.19 (a)
barley
(Hordeum vulgare)
Liliopsida Hv.12156 35
corn
(Zea mays)
Liliopsida Zm.13067 35
rice
(Oryza sativa)
Liliopsida Os02g0652800 35
  • 54.88 (n)
  • 49.89 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.9170 36
  • 50 (a)
OneToMany
Species with no ortholog for SLC37A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for SLC37A1 Gene

ENSEMBL:
Gene Tree for SLC37A1 (if available)
TreeFam:
Gene Tree for SLC37A1 (if available)

Paralogs for SLC37A1 Gene

Paralogs for SLC37A1 Gene

Selected SIMAP similar genes for SLC37A1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC37A1: view

Variants for SLC37A1 Gene

Sequence variations from dbSNP and Humsavar for SLC37A1 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type MAF
rs179185 -- 42,561,633(+) GTAGT(A/G)TGAAA intron-variant
rs190141 -- 42,548,492(+) cttgg(C/G)catgt intron-variant
rs228042 -- 42,530,194(+) AGGTA(C/T)TTTGA intron-variant
rs228043 -- 42,530,328(+) CCCTG(A/G)GTGTG intron-variant
rs228044 -- 42,531,229(+) TTCCC(C/T)GCACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC37A1 Gene

Variant ID Type Subtype PubMed ID
nsv522001 CNV Gain 19592680
nsv834103 CNV Gain 17160897
nsv521904 CNV Loss 19592680
nsv913795 CNV Loss 21882294
esv25213 CNV Loss 19812545
esv2723551 CNV Deletion 23290073
nsv913796 CNV Loss 21882294
dgv4750n71 CNV Loss 21882294
dgv4751n71 CNV Loss 21882294
nsv3533 CNV Loss 18451855
nsv913802 CNV Loss 21882294
esv2723552 CNV Deletion 23290073
esv2153018 CNV Deletion 18987734
esv2723553 CNV Deletion 23290073
esv2723554 CNV Deletion 23290073
esv2723555 CNV Deletion 23290073
esv2723556 CNV Deletion 23290073
esv4794 CNV Deletion 18987735
esv2723557 CNV Deletion 23290073
nsv187256 CNV Loss 16902084
esv2723558 CNV Deletion 23290073
esv2723559 CNV Deletion 23290073
esv2723560 CNV Deletion 23290073

Relevant External Links for SLC37A1 Gene

HapMap Linkage Disequilibrium report
SLC37A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC37A1 Gene

Disorders for SLC37A1 Gene

Relevant External Links for SLC37A1

Genetic Association Database (GAD)
SLC37A1
genes like me logo Genes that share disorders with SLC37A1: view

No data available for UniProtKB/Swiss-Prot for SLC37A1 Gene

Publications for SLC37A1 Gene

  1. Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency. (PMID: 11112347) Bartoloni L. … Antonarakis S.E. (Genomics 2000) 2 3 4 23
  2. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M. … Yaspo M.-L. (Nature 2000) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. (PMID: 15862967) Pope S.N. … Lee I.R. (J. Steroid Biochem. Mol. Biol. 2005) 3
  5. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. (PMID: 16009131) Carroll J.S. … Brown M. (Cell 2005) 3

Products for SLC37A1 Gene

  • antibodies-online peptides for SLC37A1
  • antibodies-online antibodies for SLC37A1
  • antibodies-online kits for SLC37A1

Sources for SLC37A1 Gene

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