Aliases for SLC36A4 Gene
External Ids for SLC36A4 Gene
Previous GeneCards Identifiers for SLC36A4 Gene
SLC36A4 belongs to the SLC36 family of amino acid transporters based on sequence similarity with other family members (e.g., SLC36A1; MIM 606561). SLC36 proteins contain about 500 amino acids and have 9 to 11 transmembrane domains. Unlike other SLC36 family members, which are proton-coupled amino acid transporters, SLC36A4 is a high-affinity/low-capacity non-proton-coupled amino acid transporter (Pillai and Meredith, 2011 [PubMed 21097500]).[supplied by OMIM, Feb 2011]
GeneCards Summary for SLC36A4 Gene
SLC36A4 (Solute Carrier Family 36 (Proton/Amino Acid Symporter), Member 4) is a Protein Coding gene. GO annotations related to this gene include symporter activity and amino acid transmembrane transporter activity. An important paralog of this gene is SLC36A1.
UniProtKB/Swiss-Prot for SLC36A4 Gene
Functions as a sodium-independent electroneutral transporter for tryptophan, proline and alanine. Inhibited by sarcosine.