Aliases for SLC36A1 Gene
External Ids for SLC36A1 Gene
Previous GeneCards Identifiers for SLC36A1 Gene
This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1. [provided by RefSeq, Jul 2008]
GeneCards Summary for SLC36A1 Gene
SLC36A1 (Solute Carrier Family 36 (Proton/Amino Acid Symporter), Member 1) is a Protein Coding gene. Diseases associated with SLC36A1 include allan-herndon-dudley syndrome and aminoaciduria. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Protein digestion and absorption. GO annotations related to this gene include symporter activity and L-alanine transmembrane transporter activity. An important paralog of this gene is SLC36A3.
UniProtKB/Swiss-Prot for SLC36A1 Gene
Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity).