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Aliases for SLC35G6 Gene

Aliases for SLC35G6 Gene

  • Solute Carrier Family 35, Member G6 2 3
  • Transmembrane Protein 21B 2 3 4
  • Acyl-Malonyl-Condensing Enzyme 1-Like Protein 3 3 4
  • Acyl-Malonyl Condensing Enzyme 1-Like 3 2 3
  • AMAC1L3 3 4
  • TMEM21B 3 4
  • Protein AMAC1L3 3

External Ids for SLC35G6 Gene

Previous HGNC Symbols for SLC35G6 Gene

  • TMEM21B
  • AMAC1L3

Previous GeneCards Identifiers for SLC35G6 Gene

  • GC17P007386
  • GC17P007489

Summaries for SLC35G6 Gene

GeneCards Summary for SLC35G6 Gene

SLC35G6 (Solute Carrier Family 35, Member G6) is a Protein Coding gene. An important paralog of this gene is SLC35G2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC35G6 Gene

Genomics for SLC35G6 Gene

Genomic Location for SLC35G6 Gene

7,481,332 bp from pter
7,483,496 bp from pter
2,165 bases
Plus strand

Genomic View for SLC35G6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for SLC35G6 Gene

No data available for Regulatory Elements for SLC35G6 Gene

Proteins for SLC35G6 Gene

  • Protein details for SLC35G6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 35 member G6
    Protein Accession:

    Protein attributes for SLC35G6 Gene

    338 amino acids
    Molecular mass:
    35103 Da
    Quaternary structure:
    No Data Available
    • This gene appears to be the source locus of an SVA-mediated retrotransposition event that gave rise to SLC35G3, SLC35G4 and SLC35G5 genes

neXtProt entry for SLC35G6 Gene

Proteomics data for SLC35G6 Gene at MOPED

Post-translational modifications for SLC35G6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC35G6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC35G6 Gene

Domains & Families for SLC35G6 Gene

Gene Families for SLC35G6 Gene

Protein Domains for SLC35G6 Gene


Suggested Antigen Peptide Sequences for SLC35G6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 EamA domains.
  • Belongs to the SLC35G solute transporter family.
  • Contains 2 EamA domains.
  • Belongs to the SLC35G solute transporter family.
genes like me logo Genes that share domains with SLC35G6: view

Function for SLC35G6 Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC35G6

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLC35G6 Gene

Localization for SLC35G6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC35G6 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC35G6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC35G6: view

No data available for Subcellular locations from COMPARTMENTS for SLC35G6 Gene

Pathways & Interactions for SLC35G6 Gene

SuperPathways for SLC35G6 Gene

No Data Available

Interacting Proteins for SLC35G6 Gene

Gene Ontology (GO) - Biological Process for SLC35G6 Gene


No data available for Pathways by source and SIGNOR curated interactions for SLC35G6 Gene

Drugs & Compounds for SLC35G6 Gene

No Compound Related Data Available

Transcripts for SLC35G6 Gene

mRNA/cDNA for SLC35G6 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC35G6 Gene

Solute carrier family 35, member G6:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC35G6

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC35G6 Gene

No ASD Table

Relevant External Links for SLC35G6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC35G6 Gene

mRNA expression in normal human tissues for SLC35G6 Gene

mRNA differential expression in normal tissues according to GTEx for SLC35G6 Gene

This gene is overexpressed in Testis (x32.1).

Protein differential expression in normal tissues from HIPED for SLC35G6 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SLC35G6 Gene

SOURCE GeneReport for Unigene cluster for SLC35G6 Gene Hs.632234

mRNA Expression by UniProt/SwissProt for SLC35G6 Gene

Tissue specificity: Expressed in placenta and testis.
genes like me logo Genes that share expression patterns with SLC35G6: view

Protein tissue co-expression partners for SLC35G6 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for SLC35G6 Gene

Orthologs for SLC35G6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC35G6 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia AMAC1L3 35
  • 87.28 (n)
  • 89.02 (a)
(Canis familiaris)
Mammalia LOC100688324 35
  • 87.08 (n)
  • 87.87 (a)
-- 36
  • 82 (a)
(Mus musculus)
Mammalia Slc35g3 35
  • 82.74 (n)
  • 81.95 (a)
Slc35g3 36
  • 77 (a)
(Pan troglodytes)
Mammalia AMAC1L3 35
  • 98.03 (n)
  • 95.86 (a)
SLC35G6 36
  • 96 (a)
(Rattus norvegicus)
Mammalia Slc35g3 35
  • 82.94 (n)
  • 81.36 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 69 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 52 (a)
(Danio rerio)
Actinopterygii slc35g2a 36
  • 24 (a)
slc35g2b 36
  • 24 (a)
Species with no ortholog for SLC35G6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC35G6 Gene

Gene Tree for SLC35G6 (if available)
Gene Tree for SLC35G6 (if available)

Paralogs for SLC35G6 Gene

Paralogs for SLC35G6 Gene

(4) SIMAP similar genes for SLC35G6 Gene using alignment to 1 proteins: Pseudogenes for SLC35G6 Gene

genes like me logo Genes that share paralogs with SLC35G6: view

Variants for SLC35G6 Gene

Sequence variations from dbSNP and Humsavar for SLC35G6 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
VAR_044335 -
VAR_044336 -
VAR_059581 -

Structural Variations from Database of Genomic Variants (DGV) for SLC35G6 Gene

Variant ID Type Subtype PubMed ID
esv2422288 CNV Deletion 17116639
nsv457659 CNV Loss 19166990
nsv523672 CNV Loss 19592680
dgv3054n71 CNV Loss 21882294

Variation tolerance for SLC35G6 Gene

Residual Variation Intolerance Score: 94.24% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.95; 79.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLC35G6 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC35G6 Gene

Disorders for SLC35G6 Gene

Relevant External Links for SLC35G6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SLC35G6: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC35G6 Gene

Publications for SLC35G6 Gene

  1. Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study. (PMID: 18950845) Vega A. … Carracedo A. (Gynecol. Oncol. 2009) 67
  2. Emergence of primate genes by retrotransposon-mediated sequence transduction. (PMID: 17101974) Xing J. … Batzer M.A. (Proc. Natl. Acad. Sci. U.S.A. 2006) 67
  3. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 67

Products for SLC35G6 Gene

Sources for SLC35G6 Gene

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