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Aliases for SLC35G5 Gene

Aliases for SLC35G5 Gene

  • Solute Carrier Family 35, Member G5 2 3
  • AMAC1L2 3 4 6
  • AMAC 3 4 6
  • Acyl-Malonyl-Condensing Enzyme 1-Like Protein 2 3 4
  • Acyl-Malonyl Condensing Enzyme 1-Like 2 2 3
  • Solute Carrier Family 35 Member G5 3
  • Protein AMAC1L2 3

External Ids for SLC35G5 Gene

Previous HGNC Symbols for SLC35G5 Gene

  • AMAC
  • AMAC1L2

Previous GeneCards Identifiers for SLC35G5 Gene

  • GC08P011189

Summaries for SLC35G5 Gene

Entrez Gene Summary for SLC35G5 Gene

  • This gene is intronless and probably arose from retrotransposition of a similar gene. It has high sequence similarity to the gene encoding acyl-malonyl condensing enzyme on chromosome 17. [provided by RefSeq, Aug 2011]

GeneCards Summary for SLC35G5 Gene

SLC35G5 (Solute Carrier Family 35, Member G5) is a Protein Coding gene. Diseases associated with SLC35G5 include keratolytic winter erythema. An important paralog of this gene is SLC35G2.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC35G5 Gene

Genomics for SLC35G5 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLC35G5 Gene

11,330,888 bp from pter
11,332,208 bp from pter
1,321 bases
Plus strand

Genomic View for SLC35G5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC35G5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC35G5 Gene

No data available for Regulatory Elements for SLC35G5 Gene

Proteins for SLC35G5 Gene

  • Protein details for SLC35G5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 35 member G5
    Protein Accession:
    Secondary Accessions:
    • A2RRL6

    Protein attributes for SLC35G5 Gene

    338 amino acids
    Molecular mass:
    35161 Da
    Quaternary structure:
    No Data Available
    • The gene encoding this protein appears to have arisen by SVA-mediated retrotransposition of the SLC35G6 gene in the primate lineage

neXtProt entry for SLC35G5 Gene

Proteomics data for SLC35G5 Gene at MOPED

Post-translational modifications for SLC35G5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC35G5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC35G5 Gene

Domains for SLC35G5 Gene

Gene Families for SLC35G5 Gene

Protein Domains for SLC35G5 Gene


Graphical View of Domain Structure for InterPro Entry



  • Contains 2 EamA domains.
  • Belongs to the SLC35G solute transporter family.
  • Contains 2 EamA domains.
  • Belongs to the SLC35G solute transporter family.
genes like me logo Genes that share domains with SLC35G5: view

No data available for Suggested Antigen Peptide Sequences for SLC35G5 Gene

Function for SLC35G5 Gene

Phenotypes for SLC35G5 Gene

GenomeRNAi human phenotypes for SLC35G5:
genes like me logo Genes that share phenotypes with SLC35G5: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC35G5

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC35G5 Gene

Localization for SLC35G5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC35G5 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC35G5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC35G5: view

No data available for Subcellular locations from COMPARTMENTS for SLC35G5 Gene

Pathways for SLC35G5 Gene

SuperPathways for SLC35G5 Gene

No Data Available

Interacting Proteins for SLC35G5 Gene

Gene Ontology (GO) - Biological Process for SLC35G5 Gene


No data available for Pathways by source for SLC35G5 Gene

Transcripts for SLC35G5 Gene

mRNA/cDNA for SLC35G5 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(8) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC35G5 Gene

Solute carrier family 35, member G5:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC35G5

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC35G5 Gene

No ASD Table

Relevant External Links for SLC35G5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC35G5 Gene

mRNA expression in normal human tissues for SLC35G5 Gene

mRNA differential expression in normal tissues according to GTEx for SLC35G5 Gene

This gene is overexpressed in Testis (10.2).

Protein differential expression in normal tissues for SLC35G5 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SLC35G5 Gene

SOURCE GeneReport for Unigene cluster for SLC35G5 Gene Hs.458397

mRNA Expression by UniProt/SwissProt for SLC35G5 Gene

Tissue specificity: Expressed in placenta and testis.
genes like me logo Genes that share expressions with SLC35G5: view

Expression partners for SLC35G5 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for SLC35G5 Gene

Orthologs for SLC35G5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC35G5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SLC35G5 35
  • 97.53 (n)
  • 94.97 (a)
SLC35G5 36
  • 95 (a)
(Canis familiaris)
Mammalia -- 36
  • 82 (a)
(Mus musculus)
Mammalia Slc35g3 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 69 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 53 (a)
(Danio rerio)
Actinopterygii slc35g2a 36
  • 24 (a)
slc35g2b 36
  • 24 (a)
Species with no ortholog for SLC35G5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC35G5 Gene

Gene Tree for SLC35G5 (if available)
Gene Tree for SLC35G5 (if available)

Paralogs for SLC35G5 Gene

Paralogs for SLC35G5 Gene

(3) SIMAP similar genes for SLC35G5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC35G5: view

Variants for SLC35G5 Gene

Sequence variations from dbSNP and Humsavar for SLC35G5 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs2572403 -- 11,331,835(+) CAGAC(C/G)CCCGT reference, synonymous-codon
rs2736264 -- 11,329,130(+) TTGGT(C/G)TATAT upstream-variant-2KB
rs2736265 -- 11,329,165(+) GAGGC(A/G)GGAGG upstream-variant-2KB
rs2736266 -- 11,329,925(+) ccggc(C/T)gcgac upstream-variant-2KB
rs2736267 -- 11,330,230(+) cgccc(C/T)gtccg upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SLC35G5 Gene

Variant ID Type Subtype PubMed ID
nsv831233 CNV Gain 17160897
nsv890354 CNV Gain 21882294
esv34097 CNV Loss 18971310
esv2658364 CNV Deletion 23128226

Relevant External Links for SLC35G5 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC35G5 Gene

Disorders for SLC35G5 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for SLC35G5 Gene in MalaCards »

(1) Disease for SLC35G5 Gene

genes like me logo Genes that share disorders with SLC35G5: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SLC35G5 Gene

Publications for SLC35G5 Gene

  1. Emergence of primate genes by retrotransposon-mediated sequence transduction. (PMID: 17101974) Xing J. … Batzer M.A. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3 4
  2. Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759. (PMID: 11896452) Appel S. … Rosenthal A. (Eur. J. Hum. Genet. 2002) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Common variants at 30 loci contribute to polygenic dyslipidemia. (PMID: 19060906) Kathiresan S. … Cupples L.A. (Nat. Genet. 2009) 3
  5. Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples. (PMID: 20160193) Weissglas-Volkov D. … Pajukanta P. (Circ Cardiovasc Genet 2010) 3

Products for SLC35G5 Gene

Sources for SLC35G5 Gene

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