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Aliases for SLC35G3 Gene

Aliases for SLC35G3 Gene

  • Solute Carrier Family 35, Member G3 2 3
  • Transmembrane Protein 21A 2 3 4
  • Acyl-Malonyl Condensing Enzyme 1 2 3
  • Acyl-Malonyl-Condensing Enzyme 1 3 4
  • TMEM21A 3 4
  • AMAC1 3 4
  • Protein AMAC1 3

External Ids for SLC35G3 Gene

Previous HGNC Symbols for SLC35G3 Gene

  • TMEM21A
  • AMAC1

Previous GeneCards Identifiers for SLC35G3 Gene

  • GC17M033520

Summaries for SLC35G3 Gene

GeneCards Summary for SLC35G3 Gene

SLC35G3 (Solute Carrier Family 35, Member G3) is a Protein Coding gene. Diseases associated with SLC35G3 include keratolytic winter erythema. An important paralog of this gene is SLC35G2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC35G3 Gene

Genomics for SLC35G3 Gene

Genomic Location for SLC35G3 Gene

35,192,520 bp from pter
35,194,523 bp from pter
2,004 bases
Minus strand

Genomic View for SLC35G3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC35G3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC35G3 Gene

No data available for Regulatory Elements for SLC35G3 Gene

Proteins for SLC35G3 Gene

  • Protein details for SLC35G3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 35 member G3
    Protein Accession:
    Secondary Accessions:
    • B9EGE9

    Protein attributes for SLC35G3 Gene

    338 amino acids
    Molecular mass:
    35381 Da
    Quaternary structure:
    No Data Available
    • The gene encoding this protein appears to have arisen by SVA-mediated retrotransposition of the SLC35G6 gene in the primate lineage

neXtProt entry for SLC35G3 Gene

Proteomics data for SLC35G3 Gene at MOPED

Post-translational modifications for SLC35G3 Gene

No Post-translational modifications

Other Protein References for SLC35G3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC35G3 Gene

Domains & Families for SLC35G3 Gene

Gene Families for SLC35G3 Gene

Protein Domains for SLC35G3 Gene


Suggested Antigen Peptide Sequences for SLC35G3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 EamA domains.
  • Belongs to the SLC35G solute transporter family.
  • Contains 2 EamA domains.
  • Belongs to the SLC35G solute transporter family.
genes like me logo Genes that share domains with SLC35G3: view

Function for SLC35G3 Gene

Phenotypes for SLC35G3 Gene

genes like me logo Genes that share phenotypes with SLC35G3: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC35G3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC35G3 Gene

Localization for SLC35G3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC35G3 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC35G3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC35G3: view

No data available for Subcellular locations from COMPARTMENTS for SLC35G3 Gene

Pathways & Interactions for SLC35G3 Gene

SuperPathways for SLC35G3 Gene

No Data Available

Interacting Proteins for SLC35G3 Gene

Gene Ontology (GO) - Biological Process for SLC35G3 Gene


No data available for Pathways by source and SIGNOR curated interactions for SLC35G3 Gene

Drugs & Compounds for SLC35G3 Gene

No Compound Related Data Available

Transcripts for SLC35G3 Gene

mRNA/cDNA for SLC35G3 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC35G3 Gene

Solute carrier family 35, member G3:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC35G3

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC35G3 Gene

No ASD Table

Relevant External Links for SLC35G3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC35G3 Gene

mRNA expression in normal human tissues for SLC35G3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC35G3 Gene

This gene is overexpressed in Testis (x42.3).

SOURCE GeneReport for Unigene cluster for SLC35G3 Gene Hs.514814

mRNA Expression by UniProt/SwissProt for SLC35G3 Gene

Tissue specificity: Expressed in testis.
genes like me logo Genes that share expression patterns with SLC35G3: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for SLC35G3 Gene

Orthologs for SLC35G3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC35G3 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Slc35g3 16
Slc35g3 36
  • 77 (a)
(Canis familiaris)
Mammalia -- 36
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 69 (a)
(Pan troglodytes)
Mammalia SLC35G5 36
  • 93 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 53 (a)
(Danio rerio)
Actinopterygii slc35g2a 36
  • 23 (a)
slc35g2b 36
  • 23 (a)
Species with no ortholog for SLC35G3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC35G3 Gene

Gene Tree for SLC35G3 (if available)
Gene Tree for SLC35G3 (if available)

Paralogs for SLC35G3 Gene

Paralogs for SLC35G3 Gene

(3) SIMAP similar genes for SLC35G3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC35G3: view

Variants for SLC35G3 Gene

Sequence variations from dbSNP and Humsavar for SLC35G3 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs1299732 -- 35,192,880(+) CCTTC(C/G)CCGTG utr-variant-3-prime
rs7208407 -- 35,193,244(+) TTGCC(C/T)TTATT utr-variant-3-prime
rs8079507 -- 35,193,946(+) GAACC(A/G/T)CACTG missense, reference
rs8182314 -- 35,193,052(+) CTTTA(C/T)CCCTT utr-variant-3-prime
rs9900196 -- 35,196,103(+) TTTTT(C/T)TACAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SLC35G3 Gene

Variant ID Type Subtype PubMed ID
nsv2037 CNV Loss 18451855

Variation tolerance for SLC35G3 Gene

Residual Variation Intolerance Score: 73.26% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.93; 67.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLC35G3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC35G3 Gene

Disorders for SLC35G3 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SLC35G3 Gene - From: GeneCards

Disorder Aliases PubMed IDs
keratolytic winter erythema
  • erythrokeratolysis hiemalis ichthyosis
- elite association

Relevant External Links for SLC35G3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SLC35G3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SLC35G3 Gene

Publications for SLC35G3 Gene

  1. Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759. (PMID: 11896452) Appel S. … Rosenthal A. (Eur. J. Hum. Genet. 2002) 23 67
  2. Emergence of primate genes by retrotransposon-mediated sequence transduction. (PMID: 17101974) Xing J. … Batzer M.A. (Proc. Natl. Acad. Sci. U.S.A. 2006) 67
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for SLC35G3 Gene

Sources for SLC35G3 Gene

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