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Aliases for SLC35G2 Gene

Aliases for SLC35G2 Gene

  • Solute Carrier Family 35, Member G2 2 3
  • Transmembrane Protein 22 2 3 4
  • TMEM22 3 4
  • Solute Carrier Family 35 Member G2 3

External Ids for SLC35G2 Gene

Previous HGNC Symbols for SLC35G2 Gene

  • TMEM22

Previous GeneCards Identifiers for SLC35G2 Gene

  • GC03P136538

Summaries for SLC35G2 Gene

GeneCards Summary for SLC35G2 Gene

SLC35G2 (Solute Carrier Family 35, Member G2) is a Protein Coding gene. An important paralog of this gene is SLC35G5.

UniProtKB/Swiss-Prot for SLC35G2 Gene

  • May play a role in cell proliferation.

Gene Wiki entry for SLC35G2 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC35G2 Gene

Genomics for SLC35G2 Gene

Genomic Location for SLC35G2 Gene

Start:
136,818,647 bp from pter
End:
136,855,892 bp from pter
Size:
37,246 bases
Orientation:
Plus strand

Genomic View for SLC35G2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC35G2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC35G2 Gene

No data available for Regulatory Elements for SLC35G2 Gene

Proteins for SLC35G2 Gene

  • Protein details for SLC35G2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBE7-S35G2_HUMAN
    Recommended name:
    Solute carrier family 35 member G2
    Protein Accession:
    Q8TBE7
    Secondary Accessions:
    • B2RA80
    • D3DNE1
    • Q9BWN4
    • Q9H0S6

    Protein attributes for SLC35G2 Gene

    Size:
    412 amino acids
    Molecular mass:
    46422 Da
    Quaternary structure:
    • Interacts with RAB37.
    SequenceCaution:
    • Sequence=AAH00111.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for SLC35G2 Gene

Proteomics data for SLC35G2 Gene at MOPED

Post-translational modifications for SLC35G2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC35G2 Gene

No data available for DME Specific Peptides for SLC35G2 Gene

Domains for SLC35G2 Gene

Gene Families for SLC35G2 Gene

HGNC:
  • SLC :Solute carriers

Protein Domains for SLC35G2 Gene

Blocks:
InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q8TBE7

UniProtKB/Swiss-Prot:

S35G2_HUMAN :
  • Q8TBE7
Domain:
  • Contains 2 EamA domains.
Family:
  • Belongs to the SLC35G solute transporter family.
genes like me logo Genes that share domains with SLC35G2: view

No data available for Suggested Antigen Peptide Sequences for SLC35G2 Gene

Function for SLC35G2 Gene

Molecular function for SLC35G2 Gene

UniProtKB/Swiss-Prot Function: May play a role in cell proliferation.

Phenotypes for SLC35G2 Gene

GenomeRNAi human phenotypes for SLC35G2:
genes like me logo Genes that share phenotypes with SLC35G2: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SLC35G2 Gene

Localization for SLC35G2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC35G2 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC35G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005794 Golgi apparatus IDA --
GO:0005886 plasma membrane IDA 19148500
GO:0005887 integral component of plasma membrane TAS 19148500
GO:0016020 membrane --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with SLC35G2: view

No data available for Subcellular locations from COMPARTMENTS for SLC35G2 Gene

Pathways for SLC35G2 Gene

SuperPathways for SLC35G2 Gene

No Data Available

Interacting Proteins for SLC35G2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000376794%0d%0a9606.ENSP00000002829%0d%0a
Selected Interacting proteins: Q8TBE7-S35G2_HUMAN ENSP00000376794 for SLC35G2 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for SLC35G2 Gene

None

No data available for Pathways by source for SLC35G2 Gene

Transcripts for SLC35G2 Gene

Unigene Clusters for SLC35G2 Gene

Solute carrier family 35, member G2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC35G2 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b
SP1:
SP2: - -
SP3: -

Relevant External Links for SLC35G2 Gene

GeneLoc Exon Structure for
SLC35G2
ECgene alternative splicing isoforms for
SLC35G2

Expression for SLC35G2 Gene

mRNA expression in normal human tissues for SLC35G2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for SLC35G2 Gene Hs.477692

genes like me logo Genes that share expressions with SLC35G2: view

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SLC35G2 Gene

Orthologs for SLC35G2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLC35G2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC35G2 35
  • 99.43 (n)
  • 98.79 (a)
SLC35G2 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM22 35
  • 93.43 (n)
  • 95.13 (a)
TMEM22 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLC35G2 35
  • 94.5 (n)
  • 97.09 (a)
SLC35G2 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc35g2 35
  • 88.27 (n)
  • 92.23 (a)
Slc35g2 16
Slc35g2 36
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC35G2 36
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SLC35G2 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slc35g2 35
  • 87.62 (n)
  • 91.75 (a)
chicken
(Gallus gallus)
Aves SLC35G2 35
  • 76.16 (n)
  • 78.1 (a)
SLC35G2 36
  • 77 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC35G2 36
  • 79 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc35g2 35
  • 74.27 (n)
  • 79.37 (a)
zebrafish
(Danio rerio)
Actinopterygii slc35g2b 35
  • 67.73 (n)
  • 74.45 (a)
Species with no ortholog for SLC35G2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC35G2 Gene

ENSEMBL:
Gene Tree for SLC35G2 (if available)
TreeFam:
Gene Tree for SLC35G2 (if available)

Paralogs for SLC35G2 Gene

Paralogs for SLC35G2 Gene

Selected SIMAP similar genes for SLC35G2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC35G2: view

Variants for SLC35G2 Gene

Sequence variations from dbSNP and Humsavar for SLC35G2 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1400261 -- 136,819,135(-) GGCGC(C/T)GCCCG utr-variant-5-prime
rs1400262 -- 136,819,133(-) CGCTG(C/T)CCGGA utr-variant-5-prime
rs1400263 -- 136,819,074(-) TCTCC(A/G)CCCTC utr-variant-5-prime
rs1406539 -- 136,835,081(-) aatgt(G/T)aaatt intron-variant
rs1406540 -- 136,834,904(-) gaact(C/T)gggtg intron-variant

Relevant External Links for SLC35G2 Gene

HapMap Linkage Disequilibrium report
SLC35G2
Human Gene Mutation Database (HGMD)
SLC35G2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SLC35G2 Gene

Disorders for SLC35G2 Gene

No disorders were found for SLC35G2 Gene.

No data available for UniProtKB/Swiss-Prot for SLC35G2 Gene

Publications for SLC35G2 Gene

  1. Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells. (PMID: 19148500) Dobashi S. … Nakamura Y. (Oncol. Rep. 2009) 3 4 23
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  5. New genetic associations detected in a host response study to hepatitis B vaccine. (PMID: 20237496) Davila S. … Seielstad M. (Genes Immun. 2010) 3

Products for SLC35G2 Gene

Sources for SLC35G2 Gene

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