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Aliases for SLC35F2 Gene

Aliases for SLC35F2 Gene

  • Solute Carrier Family 35, Member F2 2 3
  • Lung Squamous Cell Cancer Related Protein LSCC-3 3
  • Solute Carrier Family 35 Member F2 3
  • HSNOV1 3

External Ids for SLC35F2 Gene

Summaries for SLC35F2 Gene

GeneCards Summary for SLC35F2 Gene

SLC35F2 (Solute Carrier Family 35, Member F2) is a Protein Coding gene. An important paralog of this gene is SLC35F1.

UniProtKB/Swiss-Prot for SLC35F2 Gene

  • Putative solute transporter.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC35F2 Gene

Genomics for SLC35F2 Gene

Genomic Location for SLC35F2 Gene

Start:
107,790,991 bp from pter
End:
107,928,293 bp from pter
Size:
137,303 bases
Orientation:
Minus strand

Genomic View for SLC35F2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC35F2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC35F2 Gene

Regulatory Elements for SLC35F2 Gene

Proteins for SLC35F2 Gene

  • Protein details for SLC35F2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IXU6-S35F2_HUMAN
    Recommended name:
    Solute carrier family 35 member F2
    Protein Accession:
    Q8IXU6
    Secondary Accessions:
    • Q14963
    • Q5JPA8
    • Q6ZRQ3
    • Q9H947

    Protein attributes for SLC35F2 Gene

    Size:
    374 amino acids
    Molecular mass:
    41212 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA68226.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for SLC35F2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC35F2 Gene

Proteomics data for SLC35F2 Gene at MOPED

Post-translational modifications for SLC35F2 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys33

Other Protein References for SLC35F2 Gene

No data available for DME Specific Peptides for SLC35F2 Gene

Domains for SLC35F2 Gene

Gene Families for SLC35F2 Gene

Protein Domains for SLC35F2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

S35F2_HUMAN
Family:
  • Belongs to the SLC35F solute transporter family.:
    • Q8IXU6
genes like me logo Genes that share domains with SLC35F2: view

Function for SLC35F2 Gene

Molecular function for SLC35F2 Gene

UniProtKB/Swiss-Prot Function: Putative solute transporter.

Gene Ontology (GO) - Molecular Function for SLC35F2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with SLC35F2: view

miRNA for SLC35F2 Gene

miRTarBase miRNAs that target SLC35F2

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLC35F2 Gene

Localization for SLC35F2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC35F2 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLC35F2 Gene COMPARTMENTS Subcellular localization image for SLC35F2 gene
Compartment Confidence
plasma membrane 3
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for SLC35F2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC35F2: view

Pathways for SLC35F2 Gene

SuperPathways for SLC35F2 Gene

No Data Available

Interacting Proteins for SLC35F2 Gene

Gene Ontology (GO) - Biological Process for SLC35F2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:0008150 biological_process ND --
GO:0055085 transmembrane transport --
genes like me logo Genes that share ontologies with SLC35F2: view

No data available for Pathways by source for SLC35F2 Gene

Transcripts for SLC35F2 Gene

Unigene Clusters for SLC35F2 Gene

Solute carrier family 35, member F2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC35F2 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c
SP1: -
SP2: - -
SP3: -

Relevant External Links for SLC35F2 Gene

GeneLoc Exon Structure for
SLC35F2
ECgene alternative splicing isoforms for
SLC35F2

Expression for SLC35F2 Gene

mRNA expression in normal human tissues for SLC35F2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for SLC35F2 Gene

SOURCE GeneReport for Unigene cluster for SLC35F2 Gene Hs.524014

genes like me logo Genes that share expressions with SLC35F2: view

Orthologs for SLC35F2 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC35F2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC35F2 36
  • 99.6 (n)
  • 99.7 (a)
SLC35F2 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 96 (a)
OneToMany
-- 37
  • 80 (a)
OneToMany
dog
(Canis familiaris)
Mammalia SLC35F2 36
  • 88.86 (n)
  • 93.43 (a)
SLC35F2 37
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc35f2 36
  • 85.12 (n)
  • 89.84 (a)
Slc35f2 16
Slc35f2 37
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC35F2 37
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 95 (a)
OneToMany
-- 37
  • 87 (a)
OneToMany
chicken
(Gallus gallus)
Aves SLC35F2 36
  • 73.8 (n)
  • 77.78 (a)
SLC35F2 37
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC35F2 37
  • 67 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc35f2 36
  • 68.36 (n)
  • 71.75 (a)
Str.1493 36
zebrafish
(Danio rerio)
Actinopterygii Dr.29116 36
slc35f2 36
  • 66.24 (n)
  • 64.52 (a)
slc35f2 37
  • 52 (a)
OneToMany
SLC35F2 (2 of 2) 37
  • 61 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea Y73E7A.3 37
  • 34 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 40 (a)
OneToMany
Species with no ortholog for SLC35F2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC35F2 Gene

ENSEMBL:
Gene Tree for SLC35F2 (if available)
TreeFam:
Gene Tree for SLC35F2 (if available)

Paralogs for SLC35F2 Gene

Paralogs for SLC35F2 Gene

Selected SIMAP similar genes for SLC35F2 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with SLC35F2: view

Variants for SLC35F2 Gene

Sequence variations from dbSNP and Humsavar for SLC35F2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs471838 -- 107,840,909(-) GGCCA(G/T)GTCTC intron-variant, upstream-variant-2KB
rs474154 -- 107,835,513(+) ttcat(G/T)gcagc intron-variant
rs480641 -- 107,835,668(-) CAGAT(C/T)GCTTG intron-variant
rs482480 -- 107,835,484(-) gctcc(A/C)gtttg intron-variant
rs483369 -- 107,835,407(-) TGCCT(C/T)CCAGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC35F2 Gene

Variant ID Type Subtype PubMed ID
nsv898378 CNV Gain 21882294
nsv521771 CNV Gain 19592680
nsv527748 CNV Gain 19592680
nsv520229 CNV Gain 19592680
dgv1313n71 CNV Gain 21882294
nsv468867 CNV Loss 19166990
esv23217 CNV Gain 19812545
esv2421534 CNV Duplication 20811451
nsv442244 CNV CNV 18776908
nsv826079 CNV Loss 20364138
esv268186 CNV Insertion 20981092
esv2750980 CNV Gain 17911159
dgv1314n71 CNV Loss 21882294

Relevant External Links for SLC35F2 Gene

HapMap Linkage Disequilibrium report
SLC35F2

Disorders for SLC35F2 Gene

Relevant External Links for SLC35F2

Genetic Association Database (GAD)
SLC35F2
Human Genome Epidemiology (HuGE) Navigator
SLC35F2
genes like me logo Genes that share disorders with SLC35F2: view

No data available for UniProtKB/Swiss-Prot for SLC35F2 Gene

Publications for SLC35F2 Gene

  1. Construction of a transcription map around the gene for ataxia telangiectasia; identification of at least four novel genes. (PMID: 9119394) Stankovic T. … Taylor A.M.R. (Genomics 1997) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  5. Highly expressed SLC35F2 in non-small cell lung cancer is associated with pathological staging. (PMID: 21874247) Bu L. … Wang J. (Mol Med Rep 2011) 3

Products for SLC35F2 Gene

Sources for SLC35F2 Gene

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