SLC35F2 Gene
protein-coding GIFtS : 46
GCID: GC11 M107661
solute carrier family 35, member F2
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Aliasesfor SLC35F2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Solute Carrier Family 35, Member F2 1 2 FLJ130181 HSNOV12 Lung Squamous Cell Cancer Related Protein LSCC-32 Solute Carrier Family 35 Member F22
Export aliases for SLC35F2 gene to outside databases Previous GC identifers: GC11M107199 GC11M107166 GC11M103587
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Summariesfor SLC35F2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: S35F2_HUMAN, Q8IXU6 Function : Putative solute transporter (Potential)
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Genomic Viewsfor SLC35F2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000011.9 NC_018922.1 NT_033899.8 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SLC35F2 gene promoter: AhR FAC1 SRY POU2F1 POU2F1a MyoD HSF1 (long) HSF1short Nkx5-1 En-1 Other transcription factors Search SABiosciences Chromatin IP Primers for SLC35F2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat SLC35F2
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 11q22.3 Ensembl cytogenetic band: 11q22.3 HGNC cytogenetic band: 11q22.3 SLC35F2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 11 GeneLoc Exon Structure
GeneLoc location for GC11M107661: view genomic region
(about GC identifiers )
Start:
107,661,717 bp from pter
End:
107,799,019 bp from pter
Size:
137,303 bases
Orientation:
minus strand
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Proteinsfor SLC35F2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: S35F2_HUMAN, Q8IXU6 (See
protein sequence )Recommended Name: Solute carrier family 35 member F2 Size : 374 amino acids; 41212 Da
Subcellular location : Membrane; Multi-pass membrane protein (Potential)
Sequence caution : Sequence=CAA68226.1; Type=Erroneous initiation;
Secondary accessions : Q14963 Q5JPA8 Q6ZRQ3 Q9H947Alternative splicing : 3 isoforms : Q8IXU6-1 Q8IXU6-2 Q8IXU6-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SLC35F2: NX_Q8IXU6 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8IXU6 SLC35F2 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_059985.2 ENSEMBL proteins: ENSP00000436785 ENSP00000434307 ENSP00000434076 ENSP00000364834 ENSP00000433783 ENSP00000433461 ENSP00000393571 ENSP00000265836 Human Recombinant Protein Products: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005575 cellular_component
ND -- GO:0016021 integral to membrane
IEA --
SLC35F2 for ontologies About GeneDecksing SLC35F2 Antibody Products: Assay Products for SLC35F2:
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Protein
Domains / Familiesfor SLC35F2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
SLC35F2 for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q8IXU6 ProtoNet protein and cluster: Q8IXU6
UniProtKB/Swiss-Prot: S35F2_HUMAN, Q8IXU6 Similarity : Belongs to the SLC35F solute transporter family
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Functionfor SLC35F2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: S35F2_HUMAN, Q8IXU6 Function : Putative solute transporter (Potential)
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SLC35F2 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SLC35F2OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SLC35F2 (NM_017515 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC35F2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SLC35F2
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35F2
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0003674 molecular_function
ND --
SLC35F2 for ontologies About GeneDecksing
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Pathways & Interactionsfor SLC35F2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC35F2 STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)2 Interacting proteins for SLC35F2 (ENSP00000265836 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 2 biological process terms (GO ID links to tree view) : About this table
SLC35F2 for ontologies About GeneDecksing
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Drugs & Compoundsfor SLC35F2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for SLC35F2 Search CenterWatch for drugs/clinical trials and news about SLC35F2 / S35F2
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Transcriptsfor SLC35F2 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for SLC35F2 gene: NM_017515.4 Unigene Cluster for SLC35F2:
Solute carrier family 35, member F2 Hs.524014 [show with all ESTs ] Unigene Representative Sequence: AK128062 8 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000525815 (uc010rvu.2 uc001pjq.3 ) ENST00000525071 ENST00000533664 ENST00000375682 ENST00000532513 ENST00000524991 ENST00000429869 (uc001pjs.3 )ENST00000265836 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SLC35F2 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SLC35F2OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SLC35F2 (NM_017515 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SLC35F2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SLC35F2
Additional cDNA sequence: AK023080.1 AK128062.1 AK300582.1 AL833969.1 AY078178.1 BC039195.2 BC048302.1 X99961.1
15 DOTS entries : DT.100644214 DT.92427644
DT.99950246 DT.85104579 DT.100868243 DT.120702411 DT.120702415 DT.120711448 DT.120910227 DT.91652987 DT.91973249 DT.92010119 DT.95200484 DT.100708269 DT.120711460 24/96 AceView cDNA sequences (see all 96 ):
CA437969 BM904328 BQ015583 AL556394 AL833969 BQ013432 BX327551 AI918642 CA430138 AJ243247 AW029229 BM822891 AW410590 CB306728 CA945129 AI439654 BG289049 AL558560 AI433913 AK023080 BX485562 BI861268 AU124996 AA507009 GeneLoc Exon Structure 3 Alternative Splicing Database (ASD) splice patterns (SP) for SLC35F2 About this scheme ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c SP1 :     -               SP2 :     -   -             SP3 :       -            
ECgene alternative splicing isoforms for SLC35F2
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Expression for SLC35F2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section SLC35F2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GAAATACAAA
About this image SLC35F2 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See SLC35F2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SLC35F2 SOURCE GeneReport for Unigene cluster: Hs.524014 SABiosciences Custom PCR Arrays for SLC35F2 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for SLC35F2Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat SLC35F2 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat SLC35F2 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat SLC35F2 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35F2
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Orthologsfor SLC35F2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for SLC35F2 gene from 8/24 species (see all 24 ) About this table
ENSEMBL Gene Tree for SLC35F2 (if available)TreeFam Gene Tree for SLC35F2 (if available)
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Paralogsfor SLC35F2 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for SLC35F2 gene SLC35F1 2 1 SIMAP similar gene for SLC35F2 using alignment to 5 protein entries: S35F2_HUMAN (see all proteins ):SLC35F1
SLC35F2 for paralogs About GeneDecksing
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Genomic Variantsfor SLC35F2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 11 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for SLC35F2 (107661717 - 107799019 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for SLC35F2 5 CNVs : 48689 39087 8697 37662 66063
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing SLC35F2
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Disorders
/ Diseasesfor SLC35F2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
SLC35F2 for disorders About GeneDecksing 2 diseases for SLC35F2 : About MalaCards ataxia telangiectasia ataxia Human Genome Epidemiology (HuGE) Navigator: SLC35F2 (1 document)Export disorders for SLC35F2 gene to outside databases
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Publicationsfor SLC35F2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for SLC35F2 gene, integrated from 9 sources (see all 15 ): (articles sorted by number of sources associating them with SLC35F2) Utopia : connect your pdf to the dynamic world of online information
Construction of a transcription map around the gene for ataxia telangiectasia; identification of at least four novel genes. (PubMed id 9119394) 1 , 2 , 3 Stankovic T.... Taylor A.M.R. (1997) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983) 1 Kim W....Gygi S.P. (2011) Highly expressed SLC35F2 in non-small cell lung cance r is associated with pathological staging. (PubMed id 21874247) 1 Bu L....Wang J. (2011) Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048) 1 Danielsen J.M....Nielsen M.L. (2011) A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473) 1 Wagner S.A....Choudhary C. (2011) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231) 2 Olsen J.V....Mann M. (2010) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332) 2 Mayya V.... Han D.K. (2009) Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201) 1 Abdelmohsen K....Gorospe M. (2009)
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External Searches for SLC35F2 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing SLC35F2 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing SLC35F2 gene
(According to HUGE )
About This Section --
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Specialized Databases showing SLC35F2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for SLC35F2 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for SLC35F2 gene: Search GeneIP for patents involving SLC35F2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor SLC35F2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for SLC35F2 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for SLC35F2 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for SLC35F2 Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for SLC35F2 OriGene 3'-UTR Clone for SLC35F2 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SLC35F2 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SLC35F2 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for SLC35F2 OriGene Custom Protein Services for SLC35F2 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC35F2 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing SLC35F2 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat SLC35F2 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat SLC35F2 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat SLC35F2 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat SLC35F2
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SLC35F2 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35F2
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Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SLC35F2
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Aliases for SLC35F2
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Disorders / Diseases for SLC35F2
Domains / Families for SLC35F2
Drugs / Compounds for SLC35F2
Expression for SLC35F2
Function for SLC35F2
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Orthologs for SLC35F2
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Pathways / Interactions for SLC35F2
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Proteins for SLC35F2
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Transcripts for SLC35F2
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