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Aliases for SLC35F1 Gene

Aliases for SLC35F1 Gene

  • Solute Carrier Family 35 Member F1 2 3 5
  • C6orf169 3 4
  • Chromosome 6 Open Reading Frame 169 2
  • Solute Carrier Family 35, Member F1 2
  • DJ230I3.1 3

External Ids for SLC35F1 Gene

Previous HGNC Symbols for SLC35F1 Gene

  • C6orf169

Previous GeneCards Identifiers for SLC35F1 Gene

  • GC06P118274
  • GC06P118335
  • GC06P115810

Summaries for SLC35F1 Gene

GeneCards Summary for SLC35F1 Gene

SLC35F1 (Solute Carrier Family 35 Member F1) is a Protein Coding gene. An important paralog of this gene is SLC35F2.

UniProtKB/Swiss-Prot for SLC35F1 Gene

  • Putative solute transporter.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC35F1 Gene

Genomics for SLC35F1 Gene

Regulatory Elements for SLC35F1 Gene

Enhancers for SLC35F1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around SLC35F1 on UCSC Golden Path with GeneCards custom track

Promoters for SLC35F1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SLC35F1 on UCSC Golden Path with GeneCards custom track

Genomic Location for SLC35F1 Gene

117,907,231 bp from pter
118,317,676 bp from pter
410,446 bases
Plus strand

Genomic View for SLC35F1 Gene

Genes around SLC35F1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC35F1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC35F1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC35F1 Gene

Proteins for SLC35F1 Gene

  • Protein details for SLC35F1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 35 member F1
    Protein Accession:
    Secondary Accessions:
    • B4DJ02
    • E1P564
    • Q1RMG1
    • Q4G0U9
    • Q4G167
    • Q6N007

    Protein attributes for SLC35F1 Gene

    408 amino acids
    Molecular mass:
    45346 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH36493.1; Type=Frameshift; Positions=53, 242; Evidence={ECO:0000305};

    Alternative splice isoforms for SLC35F1 Gene


neXtProt entry for SLC35F1 Gene

Post-translational modifications for SLC35F1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC35F1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC35F1 Gene

Domains & Families for SLC35F1 Gene

Gene Families for SLC35F1 Gene

Protein Domains for SLC35F1 Gene


Suggested Antigen Peptide Sequences for SLC35F1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the SLC35F solute transporter family.
  • Belongs to the SLC35F solute transporter family.
genes like me logo Genes that share domains with SLC35F1: view

Function for SLC35F1 Gene

Molecular function for SLC35F1 Gene

UniProtKB/Swiss-Prot Function:
Putative solute transporter.
genes like me logo Genes that share phenotypes with SLC35F1: view

Animal Models for SLC35F1 Gene

MGI Knock Outs for SLC35F1:

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC35F1

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SLC35F1 Gene

Localization for SLC35F1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC35F1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC35F1 Gene COMPARTMENTS Subcellular localization image for SLC35F1 gene
Compartment Confidence
cytoskeleton 2
cytosol 2
nucleus 2
golgi apparatus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for SLC35F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC35F1: view

Pathways & Interactions for SLC35F1 Gene

SuperPathways for SLC35F1 Gene

No Data Available

Interacting Proteins for SLC35F1 Gene

Gene Ontology (GO) - Biological Process for SLC35F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
genes like me logo Genes that share ontologies with SLC35F1: view

No data available for Pathways by source and SIGNOR curated interactions for SLC35F1 Gene

Drugs & Compounds for SLC35F1 Gene

No Compound Related Data Available

Transcripts for SLC35F1 Gene

mRNA/cDNA for SLC35F1 Gene

Unigene Clusters for SLC35F1 Gene

Solute carrier family 35, member F1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC35F1 Gene

No ASD Table

Relevant External Links for SLC35F1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC35F1 Gene

mRNA expression in normal human tissues for SLC35F1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC35F1 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x6.4), Brain - Anterior cingulate cortex (BA24) (x6.1), Brain - Cortex (x4.4), Brain - Nucleus accumbens (basal ganglia) (x4.3), and Brain - Amygdala (x4.2).

Protein differential expression in normal tissues from HIPED for SLC35F1 Gene

This gene is overexpressed in Fetal Brain (47.5) and Frontal cortex (16.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SLC35F1 Gene

Protein tissue co-expression partners for SLC35F1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of SLC35F1 Gene:


SOURCE GeneReport for Unigene cluster for SLC35F1 Gene:

genes like me logo Genes that share expression patterns with SLC35F1: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for SLC35F1 Gene

Orthologs for SLC35F1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC35F1 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Slc35f1 34
  • 90.21 (n)
  • 96.65 (a)
Slc35f1 16
Slc35f1 35
  • 93 (a)
(Pan troglodytes)
Mammalia SLC35F1 34
  • 99.84 (n)
  • 100 (a)
SLC35F1 35
  • 100 (a)
(Rattus norvegicus)
Mammalia Slc35f1 34
  • 90.38 (n)
  • 96.13 (a)
(Bos Taurus)
Mammalia SLC35F1 35
  • 91 (a)
SLC35F1 34
  • 92.26 (n)
  • 98.57 (a)
(Canis familiaris)
Mammalia SLC35F1 35
  • 99 (a)
SLC35F1 34
  • 92.97 (n)
  • 98.46 (a)
(Monodelphis domestica)
Mammalia SLC35F1 35
  • 96 (a)
(Ornithorhynchus anatinus)
Mammalia SLC35F1 35
  • 77 (a)
(Gallus gallus)
Aves SLC35F1 35
  • 84 (a)
SLC35F1 34
  • 82.39 (n)
  • 92.27 (a)
(Anolis carolinensis)
Reptilia SLC35F1 35
  • 83 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc35f1 34
  • 75.07 (n)
  • 84.53 (a)
(Danio rerio)
Actinopterygii slc35f1 34
  • 74 (n)
  • 81.94 (a)
slc35f1 35
  • 78 (a)
(Caenorhabditis elegans)
Secernentea Y73E7A.3 34
  • 52.4 (n)
  • 48.49 (a)
Y73E7A.3 35
  • 35 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G59310 34
  • 51.07 (n)
  • 41.69 (a)
(Oryza sativa)
Liliopsida Os05g0299500 34
  • 50.61 (n)
  • 43.81 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU00542 34
  • 46.98 (n)
  • 36.91 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPCC320.08 34
  • 47.75 (n)
  • 39.19 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 41 (a)
Species where no ortholog for SLC35F1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC35F1 Gene

Gene Tree for SLC35F1 (if available)
Gene Tree for SLC35F1 (if available)

Paralogs for SLC35F1 Gene

Paralogs for SLC35F1 Gene

(1) SIMAP similar genes for SLC35F1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC35F1: view

Variants for SLC35F1 Gene

Sequence variations from dbSNP and Humsavar for SLC35F1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs927348 -- 118,270,944(-) AAGGG(C/T)GAGAA intron-variant
rs928597 -- 118,121,971(+) GAAAT(A/C)CTATG intron-variant
rs928598 -- 118,234,452(-) TGGGC(A/G)TTGGT intron-variant
rs928599 -- 118,234,392(-) GTTTT(A/G)TCCCA intron-variant
rs929081 -- 118,199,208(+) TCTCA(A/G)GACAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLC35F1 Gene

Variant ID Type Subtype PubMed ID
dgv1013e201 CNV deletion 23290073
dgv1014e201 CNV deletion 23290073
esv1010089 CNV deletion 20482838
esv1067063 CNV insertion 17803354
esv1466694 CNV insertion 17803354
esv1751015 CNV insertion 17803354
esv2664080 CNV deletion 23128226
esv2673331 CNV deletion 23128226
esv2732620 CNV deletion 23290073
esv2732621 CNV deletion 23290073
esv2732622 CNV deletion 23290073
esv2732623 CNV deletion 23290073
esv3305092 CNV mobile element insertion 20981092
esv3309815 CNV mobile element insertion 20981092
esv3376231 CNV insertion 20981092
esv3540359 CNV deletion 23714750
esv3610502 CNV loss 21293372
esv3610504 CNV loss 21293372
esv3610505 CNV loss 21293372
esv3610507 CNV loss 21293372
nsv1020463 CNV gain 25217958
nsv1114867 CNV deletion 24896259
nsv1121656 CNV deletion 24896259
nsv1124115 CNV deletion 24896259
nsv1133383 CNV tandem duplication 24896259
nsv428153 CNV loss 18775914
nsv476438 CNV novel sequence insertion 20440878
nsv512891 CNV insertion 21212237
nsv522455 CNV loss 19592680
nsv5452 CNV insertion 18451855
nsv604554 CNV loss 21841781
nsv830787 CNV loss 17160897
nsv930481 CNV deletion 23359205
nsv981179 CNV duplication 23825009

Variation tolerance for SLC35F1 Gene

Residual Variation Intolerance Score: 43.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.77; 16.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLC35F1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC35F1 Gene

Disorders for SLC35F1 Gene

Relevant External Links for SLC35F1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SLC35F1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC35F1 Gene

Publications for SLC35F1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 65
  2. Genome-wide association analysis identifies multiple loci related to resting heart rate. (PMID: 20639392) Eijgelsheim M. … O'Donnell C.J. (Hum. Mol. Genet. 2010) 3 46 65
  3. Common variants at ten loci influence QT interval duration in the QTGEN Study. (PMID: 19305408) Newton-Cheh C. … Stricker B.H. (Nat. Genet. 2009) 3 46 65
  4. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. (PMID: 19584346) Vasan R.S. … Blankenberg S. (JAMA 2009) 3 46 65
  5. Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies. (PMID: 19587794) Nolte I.M. … Jamshidi Y. (PLoS ONE 2009) 3 46 65

Products for SLC35F1 Gene

Sources for SLC35F1 Gene