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Aliases for SLC35E2B Gene

Aliases for SLC35E2B Gene

  • Solute Carrier Family 35 Member E2B 2 3 5
  • Solute Carrier Family 35, Member E2B 2 3
  • KIAA0447 4
  • SLC35E2 3

External Ids for SLC35E2B Gene

Previous GeneCards Identifiers for SLC35E2B Gene

  • GC01M001595
  • GC01M000871
  • GC01M001596
  • GC01M001597
  • GC01M001600
  • GC01M001604
  • GC01M001609

Summaries for SLC35E2B Gene

GeneCards Summary for SLC35E2B Gene

SLC35E2B (Solute Carrier Family 35 Member E2B) is a Protein Coding gene. An important paralog of this gene is SLC35E2.

UniProtKB/Swiss-Prot for SLC35E2B Gene

  • Putative transporter.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC35E2B Gene

Genomics for SLC35E2B Gene

Regulatory Elements for SLC35E2B Gene

Promoters for SLC35E2B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SLC35E2B on UCSC Golden Path with GeneCards custom track

Genomic Location for SLC35E2B Gene

1,659,529 bp from pter
1,692,804 bp from pter
33,276 bases
Minus strand

Genomic View for SLC35E2B Gene

Genes around SLC35E2B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC35E2B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC35E2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC35E2B Gene

Proteins for SLC35E2B Gene

  • Protein details for SLC35E2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 35 member E2B
    Protein Accession:
    Secondary Accessions:
    • B3KWR0
    • O75035
    • Q2TAY8
    • Q569F8
    • Q5CZA4
    • Q9Y3J8

    Protein attributes for SLC35E2B Gene

    405 amino acids
    Molecular mass:
    43777 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA32292.3; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for SLC35E2B Gene

Proteomics data for SLC35E2B Gene at MOPED

Post-translational modifications for SLC35E2B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC35E2B Gene

No data available for DME Specific Peptides for SLC35E2B Gene

Domains & Families for SLC35E2B Gene

Gene Families for SLC35E2B Gene

Protein Domains for SLC35E2B Gene


Suggested Antigen Peptide Sequences for SLC35E2B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TPT transporter family. SLC35E subfamily.
  • Belongs to the TPT transporter family. SLC35E subfamily.
genes like me logo Genes that share domains with SLC35E2B: view

Function for SLC35E2B Gene

Molecular function for SLC35E2B Gene

UniProtKB/Swiss-Prot Function:
Putative transporter.
genes like me logo Genes that share phenotypes with SLC35E2B: view

Animal Model Products

CRISPR Products

miRNA for SLC35E2B Gene

miRTarBase miRNAs that target SLC35E2B

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC35E2B Gene

Localization for SLC35E2B Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC35E2B Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC35E2B Gene COMPARTMENTS Subcellular localization image for SLC35E2B gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for SLC35E2B Gene

Pathways & Interactions for SLC35E2B Gene

SuperPathways for SLC35E2B Gene

No Data Available

Interacting Proteins for SLC35E2B Gene

Gene Ontology (GO) - Biological Process for SLC35E2B Gene


No data available for Pathways by source and SIGNOR curated interactions for SLC35E2B Gene

Drugs & Compounds for SLC35E2B Gene

No Compound Related Data Available

Transcripts for SLC35E2B Gene

mRNA/cDNA for SLC35E2B Gene

(4) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC35E2B Gene

Solute carrier family 35, member E2B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SLC35E2B Gene

No ASD Table

Relevant External Links for SLC35E2B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC35E2B Gene

mRNA expression in normal human tissues for SLC35E2B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SLC35E2B Gene

This gene is overexpressed in Heart (52.7) and Retina (16.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for SLC35E2B Gene

SOURCE GeneReport for Unigene cluster for SLC35E2B Gene Hs.655255

genes like me logo Genes that share expression patterns with SLC35E2B: view

Protein tissue co-expression partners for SLC35E2B Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SLC35E2B Gene

Orthologs for SLC35E2B Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SLC35E2B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SLC35E2 35
  • 82.1 (n)
  • 83.42 (a)
SLC35E2B 36
  • 83 (a)
(Canis familiaris)
Mammalia SLC35E2B 35
  • 83.66 (n)
  • 87.13 (a)
SLC35E2B 36
  • 87 (a)
(Mus musculus)
Mammalia Slc35e2 35
  • 81.35 (n)
  • 86.39 (a)
Slc35e2 16
Slc35e2 36
  • 86 (a)
(Rattus norvegicus)
Mammalia Slc35e2b 35
  • 81.11 (n)
  • 86.39 (a)
(Monodelphis domestica)
Mammalia SLC35E2B 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia SLC35E2B 36
  • 78 (a)
(Pan troglodytes)
Mammalia SLC35E2B 36
  • 100 (a)
(Gallus gallus)
Aves SLC35E2B 35
  • 73.83 (n)
  • 83.25 (a)
SLC35E2B 36
  • 81 (a)
(Anolis carolinensis)
Reptilia SLC35E2B 36
  • 81 (a)
(Danio rerio)
Actinopterygii LOC100331662 35
  • 71.43 (n)
  • 75.24 (a)
SLC35E2B 36
  • 64 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14621 36
  • 23 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G17630 35
  • 42.57 (n)
  • 32.28 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 25 (a)
Species with no ortholog for SLC35E2B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SLC35E2B Gene

Gene Tree for SLC35E2B (if available)
Gene Tree for SLC35E2B (if available)

Paralogs for SLC35E2B Gene

Paralogs for SLC35E2B Gene

(2) SIMAP similar genes for SLC35E2B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SLC35E2B: view

Variants for SLC35E2B Gene

Sequence variations from dbSNP and Humsavar for SLC35E2B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10968 -- 1,662,396(-) ATAAC(A/G)GGCCA intron-variant, utr-variant-3-prime
rs368915 -- 1,692,957(+) TCCGC(G/T)GCCGC upstream-variant-2KB
rs418743 -- 1,692,842(+) CCCCT(C/G)CCCCG upstream-variant-2KB
rs426617 -- 1,692,984(+) GGCCG(C/T)TGCAG upstream-variant-2KB
rs498739 -- 1,693,206(-) GGAAC(A/C)GCCCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SLC35E2B Gene

Variant ID Type Subtype PubMed ID
nsv10161 CNV Gain+Loss 18304495
dgv10n71 CNV Loss 21882294
dgv20n71 CNV Loss 21882294
dgv34n71 CNV Loss 21882294
nsv871837 CNV Loss 21882294
nsv871690 CNV Gain 21882294
dgv9e1 CNV Complex 17122850
dgv43n71 CNV Loss 21882294
dgv44n71 CNV Gain+Loss 21882294
nsv871954 CNV Loss 21882294
nsv871540 CNV Gain 21882294
dgv45n71 CNV Loss 21882294
nsv870847 CNV Loss 21882294
dgv46n71 CNV Loss 21882294
dgv47n71 CNV Loss 21882294
nsv871583 CNV Loss 21882294
esv27786 CNV Gain 19812545
esv2748696 CNV Deletion 23290073
dgv48n71 CNV Gain 21882294
nsv871676 CNV Loss 21882294
nsv871749 CNV Gain+Loss 21882294
nsv870598 CNV Gain 21882294
dgv2e199 CNV Deletion 23128226
dgv3n67 CNV Gain 20364138
dgv49n71 CNV Loss 21882294
dgv50n71 CNV Gain 21882294
nsv871030 CNV Gain 21882294
esv2677252 CNV Deletion 23128226
esv1758309 CNV Deletion 17803354
esv6099 CNV Gain 19470904
dgv51n71 CNV Loss 21882294
dgv10e1 CNV Complex 17122850
nsv482957 CNV Loss 15286789
dgv52n71 CNV Loss 21882294

Variation tolerance for SLC35E2B Gene

Gene Damage Index Score: 1.83; 34.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLC35E2B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC35E2B Gene

Disorders for SLC35E2B Gene

Relevant External Links for SLC35E2B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SLC35E2B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC35E2B Gene

Publications for SLC35E2B Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SLC35E2B Gene

Sources for SLC35E2B Gene

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