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Aliases for SLC35E2 Gene

Aliases for SLC35E2 Gene

  • Solute Carrier Family 35, Member E2 2 3

External Ids for SLC35E2 Gene

Previous GeneCards Identifiers for SLC35E2 Gene

  • GC01M9N0168
  • GC01M001695
  • GC01M001584
  • GC01M001587
  • GC01M001646
  • GC01M001654
  • GC01M000939

Summaries for SLC35E2 Gene

GeneCards Summary for SLC35E2 Gene

SLC35E2 (Solute Carrier Family 35, Member E2) is a Protein Coding gene. An important paralog of this gene is SLC35E1.

UniProtKB/Swiss-Prot for SLC35E2 Gene

  • Putative transporter.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC35E2 Gene

Genomics for SLC35E2 Gene

Regulatory Elements for SLC35E2 Gene

Transcription factor binding sites by QIAGEN in the SLC35E2 gene promoter:

Genomic Location for SLC35E2 Gene

1,724,838 bp from pter
1,745,999 bp from pter
21,162 bases
Minus strand

Genomic View for SLC35E2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLC35E2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC35E2 Gene

Proteins for SLC35E2 Gene

  • Protein details for SLC35E2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Solute carrier family 35 member E2
    Protein Accession:
    Secondary Accessions:
    • B3KWR0
    • O75035
    • Q2TAY8
    • Q569F8
    • Q5CZA4
    • Q5QPR8
    • Q9Y3J8

    Protein attributes for SLC35E2 Gene

    266 amino acids
    Molecular mass:
    29079 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC35E2 Gene


neXtProt entry for SLC35E2 Gene

Proteomics data for SLC35E2 Gene at MOPED

Post-translational modifications for SLC35E2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SLC35E2 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for SLC35E2 Gene

Domains & Families for SLC35E2 Gene

Gene Families for SLC35E2 Gene

Protein Domains for SLC35E2 Gene


Suggested Antigen Peptide Sequences for SLC35E2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TPT transporter family. SLC35E subfamily.
  • Belongs to the TPT transporter family. SLC35E subfamily.
genes like me logo Genes that share domains with SLC35E2: view

Function for SLC35E2 Gene

Molecular function for SLC35E2 Gene

UniProtKB/Swiss-Prot Function:
Putative transporter.

Gene Ontology (GO) - Molecular Function for SLC35E2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015297 antiporter activity IBA --
genes like me logo Genes that share ontologies with SLC35E2: view

Phenotypes for SLC35E2 Gene

GenomeRNAi human phenotypes for SLC35E2:
genes like me logo Genes that share phenotypes with SLC35E2: view

Animal Model Products

CRISPR Products

miRNA for SLC35E2 Gene

miRTarBase miRNAs that target SLC35E2

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC35E2 Gene

Localization for SLC35E2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC35E2 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SLC35E2 Gene COMPARTMENTS Subcellular localization image for SLC35E2 gene
Compartment Confidence
nucleus 2

Gene Ontology (GO) - Cellular Components for SLC35E2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC35E2: view

Pathways & Interactions for SLC35E2 Gene

SuperPathways for SLC35E2 Gene

No Data Available

Interacting Proteins for SLC35E2 Gene

Gene Ontology (GO) - Biological Process for SLC35E2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0098656 anion transmembrane transport IBA --
genes like me logo Genes that share ontologies with SLC35E2: view

No data available for Pathways by source and SIGNOR curated interactions for SLC35E2 Gene

Drugs & Compounds for SLC35E2 Gene

No Compound Related Data Available

Transcripts for SLC35E2 Gene

mRNA/cDNA for SLC35E2 Gene

Unigene Clusters for SLC35E2 Gene

Solute carrier family 35, member E2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLC35E2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC35E2 Gene

No ASD Table

Relevant External Links for SLC35E2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SLC35E2 Gene

mRNA expression in normal human tissues for SLC35E2 Gene

SOURCE GeneReport for Unigene cluster for SLC35E2 Gene Hs.707620

genes like me logo Genes that share expression patterns with SLC35E2: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SLC35E2 Gene

Orthologs for SLC35E2 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC35E2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SLC35E2 35
  • 99.32 (n)
  • 99.59 (a)
(Anolis carolinensis)
Reptilia SLC35E2 36
  • 78 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia slc35e2b 35
  • 65.64 (n)
  • 70.1 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14621 36
  • 10 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 10 (a)
Species with no ortholog for SLC35E2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SLC35E2 Gene

Gene Tree for SLC35E2 (if available)
Gene Tree for SLC35E2 (if available)

Paralogs for SLC35E2 Gene

Paralogs for SLC35E2 Gene

(1) SIMAP similar genes for SLC35E2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC35E2: view

Variants for SLC35E2 Gene

Sequence variations from dbSNP and Humsavar for SLC35E2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs7455 -- 1,727,443(-) GCAGC(C/T)GTGGT intron-variant, utr-variant-3-prime
rs16355 -- 1,728,631(-) CTCTA(A/T)CTTTC intron-variant, utr-variant-3-prime
rs710321 -- 1,730,323(+) GACTC(A/G)GGACC intron-variant, utr-variant-3-prime
rs710322 -- 1,730,265(+) GGAAA(A/G)CCAGT intron-variant, utr-variant-3-prime
rs710323 -- 1,730,206(-) CTGAA(C/T)GATTT intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SLC35E2 Gene

Variant ID Type Subtype PubMed ID
nsv10161 CNV Gain+Loss 18304495
dgv10n71 CNV Loss 21882294
dgv20n71 CNV Loss 21882294
dgv34n71 CNV Loss 21882294
nsv871690 CNV Gain 21882294
dgv9e1 CNV Complex 17122850
dgv43n71 CNV Loss 21882294
nsv871954 CNV Loss 21882294
nsv871540 CNV Gain 21882294
dgv45n71 CNV Loss 21882294
nsv871583 CNV Loss 21882294
esv27786 CNV Gain 19812545
esv2748696 CNV Deletion 23290073
dgv3n67 CNV Gain 20364138
dgv51n71 CNV Loss 21882294
dgv10e1 CNV Complex 17122850
nsv482957 CNV Loss 15286789
dgv52n71 CNV Loss 21882294
dgv53n71 CNV Gain 21882294
nsv871560 CNV Loss 21882294
nsv442858 CNV CNV 18776908
nsv436343 CNV Deletion 17901297
nsv834091 CNV Loss 17160897
nsv822475 CNV Gain 20364138
nsv822697 CNV Loss 20364138
nsv871903 CNV Gain+Loss 21882294
nsv871121 CNV Gain 21882294
essv725 CNV CNV 17122850
nsv822809 CNV Loss 20364138

Variation tolerance for SLC35E2 Gene

Residual Variation Intolerance Score: 77.18% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.43; 42.82% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SLC35E2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC35E2 Gene

Disorders for SLC35E2 Gene

Relevant External Links for SLC35E2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SLC35E2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC35E2 Gene

Publications for SLC35E2 Gene

  1. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 67
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for SLC35E2 Gene

Sources for SLC35E2 Gene

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