Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC35D3 Gene

protein-coding   GIFtS: 43
GCID: GC06P137243

Solute Carrier Family 35, Member D3


(Previous symbol: FRCL1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 35, Member D31 2
FRCL11 2 3
Fringe Connection-Like Protein 12 3
bA55K22.32
Frc, Fringe-Like 12
Solute Carrier Family 35 Member D32

External Ids:    HGNC: 156211   Entrez Gene: 3401462   Ensembl: ENSG000001827477   OMIM: 6125195   UniProtKB: Q5M8T23   

Export aliases for SLC35D3 gene to outside databases

Previous GC identifers: GC06P137178 GC06P137223 GC06P137218 GC06P137279 GC06P137287 GC06P134808


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SLC35D3 Gene: 
SLC35D3 (solute carrier family 35, member D3) is a protein-coding gene. Diseases associated with SLC35D3 include chediak-higashi syndrome, and hermansky-pudlak syndrome. An important paralog of this gene is SLC35D1.

UniProtKB/Swiss-Prot: S35D3_HUMAN, Q5M8T2
Function: May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC35D3 gene promoter:
         AhR   AML1a   Pbx1a   Arnt   E47   AREB6   Cart-1   NF-Y   CBF(2)   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SLC35D3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC35D3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q23.3   Ensembl cytogenetic band:  6q23.3   HGNC cytogenetic band: 6q23.2

SLC35D3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC35D3 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P137243:  view genomic region     (about GC identifiers)

Start:
137,243,402 bp from pter      End:
137,246,777 bp from pter
Size:
3,376 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: S35D3_HUMAN, Q5M8T2 (See protein sequence)
Recommended Name: Solute carrier family 35 member D3  
Size: 416 amino acids; 44183 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: B4DI58 Q5QNZ6 Q6NX71

Explore the universe of human proteins at neXtProt for SLC35D3: NX_Q5M8T2

Explore proteomics data for SLC35D3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5M8T2

  • SLC35D3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC35D3 Protein Expression
    REFSEQ proteins: NP_001008783.1  
    ENSEMBL proteins: 
     ENSP00000333591  

    Human Recombinant Protein Products for SLC35D3: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SLC35D3
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for SLC35D3
    GenScript Custom Purified and Recombinant Proteins Services for SLC35D3
    Novus Biologicals SLC35D3 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SLC35D3 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    SLC35D3 for ontologies           About GeneDecksing



    SLC35D3 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SLC35D3
    GenScript Custom Superior Antibodies Services for SLC35D3
    Novus Biologicals SLC35D3 Antibodies
    Abcam antibodies for SLC35D3
    Cloud-Clone Corp. Antibodies for SLC35D3 
    Search ThermoFisher Antibodies for SLC35D3
    LSBio Antibodies in human, mouse, rat for SLC35D3 

    Assay Products for SLC35D3: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SLC35D3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SLC35D3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SLC35D3 
    Cloud-Clone Corp. CLIAs for SLC35D3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: FRCL1 
    SLC35 family of nucleotide sugar transporters

    1 InterPro protein domain:
     IPR004853 DUF250

    Graphical View of Domain Structure for InterPro Entry Q5M8T2

    ProtoNet protein and cluster: Q5M8T2

    UniProtKB/Swiss-Prot: S35D3_HUMAN, Q5M8T2
    Similarity: Belongs to the TPT transporter family. SLC35D subfamily


    SLC35D3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S35D3_HUMAN, Q5M8T2
    Function: May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules (By
    similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for SLC35D3:

     Increased gamma-H2AX phosphory 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc35d3):
     hematopoietic system  homeostasis/metabolism  pigmentation 

    SLC35D3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC35D3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SLC35D3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC35D3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC35D3 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC35D3
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC35D3:
    hsa-miR-30c hsa-miR-3163 hsa-miR-30a hsa-miR-30b hsa-miR-30d hsa-miR-340 hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidSLC35D3 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SLC35D3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC35D3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SLC35D3
    Sirion Biotech Customized adenovirus for overexpression of SLC35D3

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for SLC35D3 (see all 6)
    OriGene ORF clones in mouse, rat for SLC35D3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLC35D3 (NM_001008783)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC35D3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC35D3
    Sirion Biotech Customized lentivirus for stable overexpression of SLC35D3 
                         Customized lentivirus expression plasmids for stable overexpression of SLC35D3 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SLC35D3
    Search LifeMap BioReagents cell lines for SLC35D3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35D3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC35D3

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008643carbohydrate transport IEA--

    SLC35D3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC35D3 (S35D3)

    Search CenterWatch for drugs/clinical trials and news about SLC35D3 / S35D3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC35D3 gene: 
    NM_001008783.1  

    Unigene Cluster for SLC35D3:

    Solute carrier family 35, member D3
    Hs.369703  [show with all ESTs]
    Unigene Representative Sequence: BC087842
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000331858(uc003qhe.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC35D3
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC35D3:
    hsa-miR-30c hsa-miR-3163 hsa-miR-30a hsa-miR-30b hsa-miR-30d hsa-miR-340 hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidSLC35D3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SLC35D3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC35D3
    Clone
    Products:
         
    OriGene clones in human, mouse for SLC35D3 (see all 6)
    OriGene ORF clones in mouse, rat for SLC35D3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SLC35D3 (NM_001008783)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC35D3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC35D3
    Sirion Biotech Customized lentivirus for stable overexpression of SLC35D3 
                         Customized lentivirus expression plasmids for stable overexpression of SLC35D3 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC35D3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC35D3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC35D3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC35D3

    Additional mRNA sequence: 

    AK295424.1 AK316095.1 BC067217.1 BC087842.1 

    1 DOTS entry:

    DT.99963968 

    1 AceView cDNA sequence:

    BQ888132 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC35D3 expression in normal human tissues (normalized intensities)      SLC35D3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCAAGAGT
    SLC35D3 Expression
    About this image


    SLC35D3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Epiblast (Early Embryonic Tissues)    fully expand to see all 3 entries
             Epiblast Cells Epiblast
             Epiblast Stem Cell line 5
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Striatum
             putamen   
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac
             platelets   
     
     Eye (Sensory Organs)
             Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Yolk Sac (Extraembryonic Tissues)
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac

    See SLC35D3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC35D3

    SOURCE GeneReport for Unigene cluster: Hs.369703
        SABiosciences Custom PCR Arrays for SLC35D3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SLC35D3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC35D3
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC35D3
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC35D3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35D3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC35D3 gene from 8/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc35d31 , 5 solute carrier family 35, member D31, 5 88.38(n)1
    91.35(a)1
      10 (9.12 cM)5
    761571  NM_029529.31  NP_083805.11 
     198479175 
    chicken
    (Gallus gallus)
    Aves SLC35D31 solute carrier family 35, member D3 75.45(n)
    74.39(a)
      428614  XM_426171.2  XP_426171.2 
    lizard
    (Anolis carolinensis)
    Reptilia SLC35D36
    Uncharacterized protein
    75(a)
    1 ↔ 1
    GL343200.1(2060674-2069336)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5656031 solute carrier family 35 member D3-like 63.57(n)
    64.3(a)
      565603  XM_688872.5  XP_693964.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta frc6
    fringe connection
    20(a)
    1 → many
    3L(17422036-17426290)
    worm
    (Caenorhabditis elegans)
    Secernentea sqv-76
    UDP-sugar transporter sqv-7
    22(a)
    1 → many
    II(7010798-7012692)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G316001 UDP-N-acetylglucosamine (UAA) transporter family protein 43.28(n)
    30.49(a)
      829287  NM_119309.3  NP_567879.1 
    rice
    (Oryza sativa)
    Liliopsida Os06g01881001 hypothetical protein 42.87(n)
    30.59(a)
      4340355  NM_001063555.1  NP_001057020.1 


    ENSEMBL Gene Tree for SLC35D3 (if available)
    TreeFam Gene Tree for SLC35D3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SLC35D3 gene
    SLC35D12  SLC35D22  

    SLC35D3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/118 SNPs in SLC35D3 are shown (see all 118)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1855177431,2
    --134806285(+) CAGCTA/GTTCCT 1 -- us2k10--------
    rs69287601,2
    C,F,A,H--134806402(+) TTGACC/ACCGAG 1 -- us2k1 tfbs312Minor allele frequency- A:0.50NS EA NA WA CSA 767
    rs1480757621,2
    --134806422(+) GCTCAA/CCAAAG 1 -- us2k10--------
    rs754359831,2
    F--134806602(+) AACCAC/GGAGAG 1 -- us2k11Minor allele frequency- G:0.04WA 118
    rs1149713511,2
    C,F--134806664(+) GGTTAC/TGATTC 1 -- us2k11Minor allele frequency- T:0.09WA 118
    rs1890056831,2
    --134806705(+) TGAACC/GAAAGG 1 -- us2k10--------
    rs1451474141,2
    --134806761(+) CCTGGC/TCAAGG 1 -- us2k10--------
    rs624207161,2
    C,F--134806808(+) GGCGCC/TTAACG 1 -- us2k11Minor allele frequency- T:0.50NA 2
    rs77471431,2
    C--134806816(+) ACGGTT/CACCTC 1 -- us2k13Minor allele frequency- C:0.09WA NA 240
    rs1164187051,2
    F--134806884(+) TCCAGG/AGAACT 1 -- us2k11Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for SLC35D3 (137243402 - 137246777 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SLC35D3: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC35D3
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC35D3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612519    OMIM disorders: --

    2 diseases for SLC35D3:    About MalaCards
    chediak-higashi syndrome    hermansky-pudlak syndrome

    2 diseases from the University of Copenhagen DISEASES database for SLC35D3:
    Hermansky-Pudlak syndrome     Chediak-Higashi syndrome

    SLC35D3 for disorders           About GeneDecksing


    Export disorders for SLC35D3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC35D3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SLC35D3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 340146 HGNC: 15621 AceView: SLC35D3 Ensembl:ENSG00000182747 euGenes: HUgn340146
    ECgene: SLC35D3 H-InvDB: SLC35D3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC35D3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC35D3 gene:
    Search GeneIP for patents involving SLC35D3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SLC35D3  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for SLC35D3  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SLC35D3  
     OriGene qSTAR qPCR primer pairs in human, mouse for SLC35D3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SLC35D3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SLC35D3   OriGene Custom Protein Services for SLC35D3  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC35D3
     QIAGEN SeqTarget long-range PCR primers for resequencing SLC35D3
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC35D3
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC35D3
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC35D3
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC35D3
     GenScript Custom Purified and Recombinant Proteins Services for SLC35D3 GenScript cDNA clones with any tag delivered in your preferred vector for SLC35D3
     GenScript Custom Assay Services for SLC35D3 GenScript Custom Superior Antibodies Services for SLC35D3
     GenScript Custom overexpressing Cell Line Services for SLC35D3 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SLC35D3 promoter
     Search Chromatin IP Primers for SLC35D3
     RT2 qPCR Primer Assay in human, mouse, rat SLC35D3
     Search GNC Networks for SLC35D3
     SABiosciences Custom PCR Arrays for SLC35D3
     Search Tocris compounds for SLC35D3 (S35D3)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     SLC35D3 antibodies
     SLC35D3 proteins
     Antibodies for SLC35D3
     See all of Abcam's Antibodies, Kits and Proteins for SLC35D3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for SLC35D3
     Antibodies for SLC35D3
     ELISAs for SLC35D3
     CLIAs for SLC35D3
     Search LifeMap BioReagents cell lines for SLC35D3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35D3
     SwitchGear 3'UTR luciferase reporter plasmids for SLC35D3
     Browse SwitchGear Promoter luciferase reporter plasmids for SLC35D3
     Search ThermoFisher Antibodies for SLC35D3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC35D3
     inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC35D3
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SLC35D3
    Customized:
     lentivirus for stable overexpression of SLC35D3
     lentivirus expression plasmids for stable overexpression of SLC35D3
     adenovirus for overexpression of SLC35D3
     LSBio Antibodies in human, mouse, rat for SLC35D3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SLC35D3 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4