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SLC35D2 Gene

protein-coding   GIFtS: 51
GCID: GC09M099082

Solute Carrier Family 35 (UDP-GlcNAc/UDP-Glucose Transporter),...

(Previous names: solute carrier family 35, member D2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 35 (UDP-GlcNAc/UDP-Glucose Transporter), Member
D21 2
     Fringe Connection2
HFRC12 3 5     hfrc2
SQV7L2 3 5     UDP-N-Acetylglucosamine Transporter2
Solute Carrier Family 35, Member D21 2     UDP-N-Acetylglucosamine/UDP-Glucose/GDP-Mannose Transporter2
Homolog Of Fringe Connection Protein 12 3     HFRC3
UGTrel82 3     UGTREL83
SQV7-Like Protein2 3     Solute Carrier Family 35 Member D23
UDP-Galactose Transporter-Related Protein 82 3     

External Ids:    HGNC: 207991   Entrez Gene: 110462   Ensembl: ENSG000001309587   OMIM: 6091825   UniProtKB: Q76EJ33   

Export aliases for SLC35D2 gene to outside databases

Previous GC identifers: GC09M092533 GC09M094462 GC09M096162 GC09M098122 GC09M068694


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC35D2 Gene:
Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for
glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of
nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar
transporters, such as SLC35D2 (Suda et al., 2004 (PubMed 15082721)).(supplied by OMIM, Mar 2008)

GeneCards Summary for SLC35D2 Gene:
SLC35D2 (solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2) is a protein-coding gene. Diseases associated with SLC35D2 include sly syndrome, and shigellosis. GO annotations related to this gene include nucleotide-sugar transmembrane transporter activity. An important paralog of this gene is SLC35D3.

UniProtKB/Swiss-Prot: S35D2_HUMAN, Q76EJ3
Function: Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose
(UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the
corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan
sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC35D2 gene promoter:
         TBP   FOXO3   FOXO3b   C/EBPalpha   PPAR-gamma1   Nkx6-1   TFIID   FOXO3a   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC35D2 promoter sequence
   Search Chromatin IP Primers for SLC35D2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC35D2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.32   Ensembl cytogenetic band:  9q22.32   HGNC cytogenetic band: 9q22.33

SLC35D2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC35D2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M099082:  view genomic region     (about GC identifiers)

Start:
99,082,988 bp from pter      End:
99,145,992 bp from pter
Size:
63,005 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: S35D2_HUMAN, Q76EJ3 (See protein sequence)
Recommended Name: UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter  
Size: 337 amino acids; 36673 Da
Secondary accessions: O95454 Q498C1 Q75W21 Q7Z5X5
Alternative splicing: 2 isoforms:  Q76EJ3-1   Q76EJ3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC35D2: NX_Q76EJ3

Explore proteomics data for SLC35D2 at MOPED


See SLC35D2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_001273919.1  NP_008932.2  

ENSEMBL proteins: 
 ENSP00000253270   ENSP00000364406   ENSP00000364408  
Reactome Protein details: Q76EJ3

SLC35D2 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
SLC: Solute carriers

IUPHAR Guide to PHARMACOLOGY protein family classification: HFRC1
SLC35 family of nucleotide sugar transporters

1 InterPro protein domain:
 IPR004853 Tpt_PEP_trans_dom

Graphical View of Domain Structure for InterPro Entry Q76EJ3

ProtoNet protein and cluster: Q76EJ3

UniProtKB/Swiss-Prot: S35D2_HUMAN, Q76EJ3
Similarity: Belongs to the TPT transporter family. SLC35D subfamily


SLC35D2 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: S35D2_HUMAN, Q76EJ3
Function: Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose
(UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the
corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan
sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling
Biophysicochemical properties: Kinetic parameters: KM=8 uM for UDP-N-acetylglucosamine; KM=2.1 uM for UDP-glucose;
KM=0.14 uM for GDP-mannose;

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005338nucleotide-sugar transmembrane transporter activity NAS9927678
     
SLC35D2 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLC35D2
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miRNA
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miRTarBase miRNAs that target SLC35D2:
hsa-mir-98-5p (MIRT027692), hsa-mir-193b-3p (MIRT016425), hsa-mir-26b-5p (MIRT029531)

Block miRNA regulation of human, mouse, rat SLC35D2 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SLC35D2 (see all 12):
hsa-miR-98 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-let-7i hsa-miR-196a hsa-let-7e hsa-let-7g
SwitchGear 3'UTR luciferase reporter plasmidSLC35D2 3' UTR sequence
Inhib. RNA
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
S35D2_HUMAN, Q76EJ3: Golgi apparatus membrane; Multi-pass membrane protein
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
golgi apparatus5
plasma membrane3
endoplasmic reticulum1

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000139Golgi membrane TAS--
GO:0005575cellular_component ND--
GO:0016021integral component of membrane IEA--

SLC35D2 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for SLC35D2 About   (see all 7)  
See pathways by source

SuperPathSelected contained pathways About (see all per SuperPath)
1MPS VI - Maroteaux-Lamy syndrome
MPS VI - Maroteaux-Lamy syndrome0.45
MPS IIIB - Sanfilippo syndrome B0.45
MPS IIIC - Sanfilippo syndrome C0.45
MPS II - Hunter syndrome0.45
MPS IV - Morquio syndrome A0.45
Glycosaminoglycan metabolism0.45
Mucopolysaccharidoses0.45
MPS IV - Morquio syndrome B0.45
2Keratan sulfate/keratin metabolism
Keratan sulfate/keratin metabolism0.85
Keratan sulfate biosynthesis0.85
3Heparan sulfate/heparin (HS-GAG) metabolism
Heparan sulfate/heparin (HS-GAG) metabolism0.57
HS-GAG biosynthesis0.57
4Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
SLC-mediated transmembrane transport0.47
Transmembrane transport of small molecules0.47
5Transport of vitamins, nucleosides, and related molecules
Transport of vitamins, nucleosides, and related molecules
Transport of nucleotide sugars0.00

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


3 Reactome Pathways for SLC35D2
    HS-GAG biosynthesis
Keratan sulfate biosynthesis
Transport of nucleotide sugars



SLC35D2 for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC35D2
Interactions:

    Search GeneGlobe Interaction Network for SLC35D2

STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

Selected Interacting proteins for SLC35D2 (ENSP000002532704) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
InteractantInteraction Details
GeneCardExternal ID(s)
NOTCH1ENSP000002775414STRING: ENSP00000277541
NOTCH2ENSP000002566464STRING: ENSP00000256646
NOTCH2NLENSP000003549294STRING: ENSP00000354929
NOTCH3ENSP000002633884STRING: ENSP00000263388
ROS1ENSP000003574944STRING: ENSP00000357494
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Gene Ontology (GO): Selected biological process terms (see all 11):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005975carbohydrate metabolic process TAS--
GO:0006024glycosaminoglycan biosynthetic process TAS--
GO:0008150biological_process ND--
GO:0008643carbohydrate transport IEA--
GO:0018146keratan sulfate biosynthetic process TAS--

SLC35D2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for SLC35D2 (S35D2)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for SLC35D2 gene (2 alternative transcripts): 
NM_001286990.1  NM_007001.2  

Unigene Cluster for SLC35D2:

Solute carrier family 35, member D2
Hs.494556  [show with all ESTs]
Unigene Representative Sequence: AK307890
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000490599 ENST00000253270(uc010msd.3 uc004awc.3) ENST00000375257
ENST00000482643 ENST00000375259(uc010msf.3)
miRNA
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Selected qRT-PCR Assays for microRNAs that regulate SLC35D2 (see all 12):
hsa-miR-98 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-let-7i hsa-miR-196a hsa-let-7e hsa-let-7g
SwitchGear 3'UTR luciferase reporter plasmidSLC35D2 3' UTR sequence
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GenScript: all cDNA clones in your preferred vector: SLC35D2 (NM_007001)
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  QuantiFast Probe-based Assays in human, mouse, rat SLC35D2

Additional mRNA sequence: 

AB106537.1 AB122077.1 AJ005866.1 AK307890.1 BC009413.1 BC015146.2 BC100278.1 BC113579.1 

9 DOTS entries:

DT.100750159  DT.95344110  DT.100019040  DT.121183296  DT.121618641  DT.315026  DT.92423751  DT.95291721 
DT.97771598 

Selected AceView cDNA sequences (see all 140):

AA302781 AI741817 AA937708 AI608819 AI076435 CR614216 AI273232 N57456 
BM761207 AI084676 BM924430 CA394282 BM761346 CR615006 AI475475 BM675407 
AI341877 BU623156 BE049423 BE349543 AA781317 CR605179 AA586604 AK024841 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for SLC35D2    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
SP1:                          -           -                                             
SP2:                          -           -     -     -     -                           
SP3:                          -                                                         
SP4:              -     -     -     -     -     -     -     -                           
SP5:                                                                                    


ECgene alternative splicing isoforms for SLC35D2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SLC35D2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TCTTTAGTCT
SLC35D2 Expression
About this image

SLC35D2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

SLC35D2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.494556

UniProtKB/Swiss-Prot: S35D2_HUMAN, Q76EJ3
Tissue specificity: Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood
leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus

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In Situ
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35D2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for SLC35D2 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Slc35d21 , 5 solute carrier family 35, member D21, 5 87.72(n)1
91.33(a)1
  13 (33.26 cM)5
704841  NM_001001321.31  NP_001001321.21 
 640963105 
chicken
(Gallus gallus)
Aves SLC35D21 solute carrier family 35, member D2 72.63(n)
72.14(a)
  101751744  XM_004951107.1  XP_004951164.1 
lizard
(Anolis carolinensis)
Reptilia SLC35D26
solute carrier family 35 (UDP-GlcNAc/UDP-glucose t...
73(a)
1 ↔ 1
2(39991421-40018558)
tropical clawed frog
(Xenopus tropicalis)
Amphibia Str.166672 Transcribed sequence with weak similarity to protein refNP_055954.1 (H.sapiens) UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter; KIAA0260 protein; UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter [Homo sapiens] less 73.68(n)    BX716400.1 
zebrafish
(Danio rerio)
Actinopterygii LOC1005349281 UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter-like less 63.14(n)
62.18(a)
  100534928  XM_003199035.2  XP_003199083.2 
fruit fly
(Drosophila melanogaster)
Insecta frc6
fringe connection
39(a)
1 → many
3L(17422036-17426290)
worm
(Caenorhabditis elegans)
Secernentea sqv-76
Protein SQV-7 (sqv-7) mRNA, complete cds
46(a)
1 → many
II(7010798-7012690) WBGene00005025


ENSEMBL Gene Tree for SLC35D2 (if available)
TreeFam Gene Tree for SLC35D2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for SLC35D2 gene
SLC35D32  SLC35D12  
1 SIMAP similar gene for SLC35D2 using alignment to 2 protein entries:     S35D2_HUMAN (see all proteins):
SLC35D1

SLC35D2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for SLC35D2 (see all 1401)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 9 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs78543771,2
C,F,A--99082626(+) AACCTT/CGTCTC 1 -- int17Minor allele frequency- C:0.17WA NA CSA EA 365
rs1472434201,2
--99082690(+) CTACTC/TGGGAG 1 -- int10--------
rs1851594651,2
--99082747(+) GAGCCA/GAGATT 1 -- int10--------
rs113328111,2
C--99082798(+) GTCTC-/AAAAAA 1 -- int11Minor allele frequency- A:0.00CSA 2
rs348708061,2
C--99082798(+) GTCTC-/AAAAAAA 1 -- int10--------
rs1390493521,2
--99082922(+) GTGACA/GCATTC 1 -- int10--------
rs759749561,2
F--99082929(+) ATTCTG/ATTACA 1 -- int11Minor allele frequency- A:0.02WA 118
rs1898204171,2
--99082939(+) ATTGTC/GAATGA 1 -- int10--------
rs1436861971,2
C--99083332(+) GTGTCA/GCCCGA 1 -- ut310--------
rs1830527131,2
--99083336(+) CGCCCA/GAGTAC 1 -- ut310--------

HapMap Linkage Disequilibrium report for SLC35D2 (99082988 - 99145992 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for SLC35D2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv893602CNV Gain21882294
nsv893603CNV Gain21882294

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 609182    OMIM disorders: --

5 diseases for SLC35D2:    
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sly syndrome    shigellosis    mucopolysaccharidoses    morquio syndrome b
lung cancer


SLC35D2 for disorders           About GeneDecksing


Export disorders for SLC35D2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for SLC35D2 gene, integrated from 10 sources (see all 11):
(articles sorted by number of sources associating them with SLC35D2)
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world of online information

  1. Identification and characterization of human Golgi nucleotide sugar transporter SLC35D2, a novel member of the SLC35 nucleotide sugar transporter family. (PubMed id 15607426)1, 2, 3, 9 Ishida N.... Sanai Y. (Genomics 2005)
  2. Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection. (PubMed id 15082721)1, 2, 9 Suda T.... Nishihara S. (J. Biol. Chem. 2004)
  3. Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway. (PubMed id 9927678)1, 2 Herman T. and Horvitz H.R. (Proc. Natl. Acad. Sci. U.S.A. 1999)
  4. Genome-wide meta-analysis identifies new susceptibility loci for migraine. (PubMed id 23793025)1 Anttila V.... . (Nat. Genet. 2013)
  5. Prognostic implications of genetic variants in advanced non-small cell lung cancer: a genome-wide association study. (PubMed id 23144319)1 Lee Y....Lee J.S. (Carcinogenesis 2013)
  6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
  7. Endoplasmic reticulum/golgi nucleotide sugar transporters contribute to the cellular release of UDP-sugar signaling molecules. (PubMed id 19276090)1 Sesma J.I....Lazarowski E.R. (J. Biol. Chem. 2009)
  8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  9. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (Nature 2004)
  10. Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35). (PubMed id 12759756)1 Ishida N. and Kawakita M. (Pflugers Arch. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11046 HGNC: 20799 AceView: SLC35D2 Ensembl:ENSG00000130958 euGenes: HUgn11046
ECgene: SLC35D2 H-InvDB: SLC35D2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for SLC35D2 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for SLC35D2 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SLC35D2 gene:
Search GeneIP for patents involving SLC35D2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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