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SLC35C2 Gene

protein-coding   GIFtS: 48
GCID: GC20M044978

Solute Carrier Family 35 (GDP-Fucose Transporter), Member...

(Previous names: ovarian cancer overexpressed 1, solute carrier family 35,...)
(Previous symbols: C20orf5, OVCOV1)
  See SLC35C2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Solute Carrier Family 35 (GDP-Fucose Transporter), Member C21 2     Solute Carrier Family 35, Member C21
C20orf51 2 3     BA394O2.12
OVCOV11 2 3     CGI-152
Ovarian Cancer-Overexpressed Gene 1 Protein2 3     Solute Carrier Family 35 Member C22
Ovarian Cancer Overexpressed 11     

External Ids:    HGNC: 171171   Entrez Gene: 510062   Ensembl: ENSG000000801897   UniProtKB: Q9NQQ73   

Export aliases for SLC35C2 gene to outside databases

Previous GC identifers: GC20M045616 GC20M045663 GC20M044411 GC20M041719


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLC35C2 Gene:
This gene encodes a member of the triose-phosphate transporter protein family. This gene is regulated by oxygen
tension, is induced in hypoxic trophoblast cells, and is overexpressed in ovarian cancer. Alternative splicing
results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.
(provided by RefSeq, Jul 2013)

GeneCards Summary for SLC35C2 Gene:
SLC35C2 (solute carrier family 35 (GDP-fucose transporter), member C2) is a protein-coding gene. Diseases associated with SLC35C2 include ovarian cancer.

UniProtKB/Swiss-Prot: S35C2_HUMAN, Q9NQQ7
Function: May play an important role in the cellular response to tissue hypoxia

Gene Wiki entry for SLC35C2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000020.10  NT_011362.11  NC_018931.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SLC35C2 gene promoter:
         Nkx3-1   Nkx3-1 v4   Nkx3-1 v1   Nkx3-1 v2   POU2F1   POU2F1a   Zic1   Sox9   Nkx3-1 v3   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSLC35C2 promoter sequence
   Search Chromatin IP Primers for SLC35C2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLC35C2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.12   Ensembl cytogenetic band:  20q13.12   HGNC cytogenetic band: 20q13.12

SLC35C2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC35C2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M044978:  view genomic region     (about GC identifiers)

Start:
44,978,167 bp from pter      End:
44,993,064 bp from pter
Size:
14,898 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: S35C2_HUMAN, Q9NQQ7 (See protein sequence)
Recommended Name: Solute carrier family 35 member C2  
Size: 365 amino acids; 40432 Da
Sequence caution: Sequence=AAD27724.1; Type=Frameshift; Positions=168, 211, 305;
Secondary accessions: E1P5T0 Q5JW05 Q96CJ8 Q9Y304
Alternative splicing: 2 isoforms:  Q9NQQ7-1   Q9NQQ7-2   

Explore the universe of human proteins at neXtProt for SLC35C2: NX_Q9NQQ7

Explore proteomics data for SLC35C2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys331
  • Glycosylation2 at Asn102
  • Modification sites at PhosphoSitePlus

  • See SLC35C2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001268386.1  NP_001268387.1  NP_001268388.1  NP_001268389.1  NP_057029.8  NP_775096.1  NP_775271.1  

    ENSEMBL proteins: 
     ENSP00000361301   ENSP00000361303   ENSP00000361304   ENSP00000243896   ENSP00000318960  
     ENSP00000397142   ENSP00000415736   ENSP00000439974  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: OVCOV1
    SLC35 family of nucleotide sugar transporters

    1 InterPro protein domain:
     IPR004853 Tpt_PEP_trans_dom

    Graphical View of Domain Structure for InterPro Entry Q9NQQ7

    ProtoNet protein and cluster: Q9NQQ7

    1 Blocks protein domain: IPB002198 Short-chain dehydrogenase/reductase SDR

    UniProtKB/Swiss-Prot: S35C2_HUMAN, Q9NQQ7
    Similarity: Belongs to the TPT transporter family. SLC35C subfamily


    Find genes that share domains with SLC35C2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: S35C2_HUMAN, Q9NQQ7
    Function: May play an important role in the cellular response to tissue hypoxia
    Induction: In hypoxic trophoblast cells

    Animal Models:

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    hsa-miR-125a-3p hsa-miR-377 hsa-miR-1207-5p hsa-miR-3921
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    S35C2_HUMAN, Q9NQQ7: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    endoplasmic reticulum1
    golgi apparatus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005793endoplasmic reticulum-Golgi intermediate compartment IDA--
    GO:0005801cis-Golgi network IDA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with SLC35C2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SLC35C2
    Interactions:

        Search GeneGlobe Interaction Network for SLC35C2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for SLC35C2 (Q9NQQ73 ENSP000002438964) via UniProtKB, MINT, STRING, and/or I2D (see all 31)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    SLC25A37Q9NYZ23, ENSP000002900754I2D: score=1 STRING: ENSP00000290075
    ACO2Q997983I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0010629negative regulation of gene expression IEA--
    GO:0036065fucosylation ----
    GO:0036066protein O-linked fucosylation IEA--
    GO:0045747positive regulation of Notch signaling pathway IEA--

    Find genes that share ontologies with SLC35C2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SLC35C2 (S35C2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SLC35C2 gene (7 alternative transcripts): 
    NM_001281457.1  NM_001281458.1  NM_001281459.1  NM_001281460.1  NM_015945.11  NM_173073.3  NM_173179.3  

    Unigene Cluster for SLC35C2:

    Solute carrier family 35, member C2
    Hs.593344  [show with all ESTs]
    Unigene Representative Sequence: AK128842
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000493599 ENST00000372227(uc002xro.3) ENST00000372229 ENST00000372230
    ENST00000243896(uc002xrq.3 uc002xrr.3 uc010zxo.2 uc010zxp.2)
    ENST00000317734(uc002xrp.3 uc010zxn.2) ENST00000480329 ENST00000487729
    ENST00000484318 ENST00000481809 ENST00000420518 ENST00000424568 ENST00000484188
    ENST00000543605
    miRNA
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    hsa-miR-125a-3p hsa-miR-377 hsa-miR-1207-5p hsa-miR-3921
    SwitchGear 3'UTR luciferase reporter plasmidSLC35C2 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat SLC35C2

    Additional mRNA sequence: 

    AF455052.1 AK128842.1 AK222928.1 AK300207.1 AK300798.1 AK301022.1 AK315726.1 BC014191.2 
    BC021138.1 BC025277.1 

    Selected DOTS entries (see all 32):

    DT.86838315  DT.100667213  DT.100030813  DT.100667205  DT.452614  DT.101956033  DT.100030810  DT.105931 
    DT.100667209  DT.100809371  DT.97850424  DT.95264048  DT.100667208  DT.120808760  DT.120808757  DT.120808772 
    DT.91676318  DT.100667210  DT.95264053  DT.100770858  DT.101984761  DT.102828137  DT.75130565  DT.95264051 

    Selected AceView cDNA sequences (see all 391):

    BX385332 CR612094 BX401334 BU625167 BM712724 BM763590 CA448399 BM984874 
    BG683174 CK905871 CR593672 BM046277 BM985367 AA451942 AA347636 NM_173073 
    BQ690761 BM824296 BG026633 BI489990 BM924054 BM545876 CR609774 BU194602 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SLC35C2 (see all 29)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9a · 9b · 9c ·
    SP1:                                -     -     -     -     -     -                                                                       -     -               
    SP2:                                                                                                                                      -     -               
    SP3:                                -     -     -     -     -     -                                                                       -     -               
    SP4:                                -     -     -     -     -     -                                         -                             -     -               
    SP5:                                                                                                        -                             -     -               

    ExUns: 9d ^ 10a · 10b ^ 11a · 11b · 11c · 11d · 11e ^ 12a · 12b ^ 13a · 13b · 13c · 13d · 13e ^ 14a · 14b ^ 15a · 15b
    SP1:  -           -     -     -     -                             -                                   -               
    SP2:  -           -     -                                         -                                   -               
    SP3:  -           -     -                                         -                                                   
    SP4:  -           -     -     -     -                                                                                 
    SP5:  -           -     -     -     -                             -                                                   


    ECgene alternative splicing isoforms for SLC35C2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SLC35C2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTTTGCCC
    SLC35C2 Expression
    About this image


    SLC35C2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Neural Tube (Nervous System)
             Metencephalon
    SLC35C2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SLC35C2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.593344

    UniProtKB/Swiss-Prot: S35C2_HUMAN, Q9NQQ7
    Tissue specificity: Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in
    ovarian cancer

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SLC35C2 gene from Selected species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc35c21 , 5 solute carrier family 35, member C21, 5 88.37(n)1
    94.78(a)1
      2 (85.53 cM)5
    2288751  NM_001252573.11  NP_001239502.11 
     1652765545 
    chicken
    (Gallus gallus)
    Aves SLC35C21 solute carrier family 35, member C2 72.35(n)
    72.65(a)
      419306  NM_001030865.1  NP_001026036.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC35C26
    solute carrier family 35 (GDP-fucose transporter),...
    73(a)
    1 ↔ 1
    GL344019.1(3217-6923)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.60852 Xenopus laevis transcribed sequence with weak similarity more 74.26(n)    BX844175.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.79732 Danio rerio mRNA similar to ovarian cancer overexpressed more 74.89(n)    BC045291.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG149711 CG14971 55.48(n)
    47.95(a)
      38429  NM_139560.4  NP_647817.2 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y47G6A.71 CELE_Y47G6A.7 47.67(n)
    42.67(a)
      171918  NM_001026599.3  NP_001021770.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YMD8(YML038C)4
    YMD81
    Putative nucleotide sugar transporter, has similarity more4
    YMD81
    44.41(n)1
    35.29(a)1
      13(204103-202775)4
    8549701, 4  NP_013674.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G064701 AT1G06470 45.86(n)
    36.9(a)
      837159  NM_202043.2  NP_973772.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g07499001 Os01g0749900 46.78(n)
    36.61(a)
      4324622  NM_001050784.1  NP_001044249.1 


    ENSEMBL Gene Tree for SLC35C2 (if available)
    TreeFam Gene Tree for SLC35C2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SLC35C2 gene

    Find genes that share paralogs with SLC35C2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for SLC35C2
    PGOHUM00000260901


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SLC35C2 (see all 381)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1163101041,2
    C,F--44977697(+) CCACCC/AATGGA 3 -- ds50011Minor allele frequency- A:0.04WA 118
    rs1441242061,2
    --44977729(+) CACCCC/GTTTTC 3 -- ds50010--------
    rs1485183901,2
    --44977800(+) GGCGCC/TACCTG 3 -- ds50010--------
    rs1862071261,2
    --44977812(+) TGTGAA/GTGCCT 3 -- ds50010--------
    rs1898278191,2
    --44977846(+) TTGTCC/TCCAAG 3 -- ds50010--------
    rs1156380721,2
    F--44977986(+) GGACTT/CGGCCA 3 -- ds50011Minor allele frequency- C:0.01WA 118
    rs1822733681,2
    --44978009(+) AAGCCC/GAAGCC 3 -- ds50010--------
    rs48095881,2
    C,F,A,H--44978021(+) CAGGGT/GCCCAT 3 -- ds500125Minor allele frequency- G:0.29NS EA NA CSA WA 2473
    rs1453478541,2
    C--44978074(+) ACACAC/GAGACG 3 -- ds50010--------
    rs1865476991,2
    --44978148(+) TTAGTC/TTCTTA 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for SLC35C2 (44978167 - 44993064 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SLC35C2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2722457CNV Deletion23290073
    nsv912899CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC35C2
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC35C2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for SLC35C2:    
    About MalaCards
    ovarian cancer


    Find genes that share disorders with SLC35C2           About GenesLikeMe

    Genetic Association Database (GAD): SLC35C2

    Export disorders for SLC35C2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SLC35C2 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with SLC35C2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Identification, molecular characterization, and tissue expression of OVCOV1. (PubMed id 12461647)1, 2 Leach R.E.... Krawetz S.A. (Mamm. Genome 2002)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    5. Assignment of OVCOV1 (alias CGI-15) to human chromosome 20 band q13.1-->q13.2 by fluorescent in situ hybridization. (PubMed id 11856893)1, 2 Leach R.E....Krawetz S.A. (Cytogenet. Cell Genet. 2001)
    6. A high-resolution 6.0-megabase transcript map of the type 2 diabetes susceptibility region on human chromosome 20. (PubMed id 11549316)1, 3 Fossey S.C....Bowden D.W. (Genomics 2001)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51006 HGNC: 17117 AceView: SLC35C2 Ensembl:ENSG00000080189 euGenes: HUgn51006
    ECgene: SLC35C2 H-InvDB: SLC35C2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SLC35C2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SLC35C2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SLC35C2 gene:
    Search GeneIP for patents involving SLC35C2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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