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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC35C1 Gene

protein-coding   GIFtS: 53
GCID: GC11P045826

Solute Carrier Family 35 (GDP-Fucose Transporter), Member...

(Previous names: solute carrier family 35, member C1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Solute Carrier Family 35 (GDP-Fucose Transporter), Member C11 2
FUCT12 3 5
Solute Carrier Family 35, Member C11 2
CDG2C2 5
GDP-Fucose Transporter 12
Solute Carrier Family 35 Member C13

External Ids:    HGNC: 201971   Entrez Gene: 553432   Ensembl: ENSG000001818307   OMIM: 6058815   UniProtKB: Q96A293   

Export aliases for SLC35C1 gene to outside databases

Previous GC identifers: GC00U913330 GC11P045791 GC11P045792 GC11P045783 GC11P045532


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC35C1 Gene:
This gene encodes a GDP-fucose transporter that is found in the Golgi apparatus. Mutations in this gene result in
congenital disorder of glycosylation type IIc. Multiple transcript variants encoding different isoforms have been
found for this gene. (provided by RefSeq, Feb 2009)

GeneCards Summary for SLC35C1 Gene: 
SLC35C1 (solute carrier family 35 (GDP-fucose transporter), member C1) is a protein-coding gene. Diseases associated with SLC35C1 include congenital disorder of glycosylation type 2c, and leukocyte adhesion deficiency, and among its related super-pathways are Transmembrane transport of small molecules and Transport of organic anions.

UniProtKB/Swiss-Prot: FUCT1_HUMAN, Q96A29
Function: Involved in GDP-fucose import from the cytoplasm into the Golgi lumen

Gene Wiki entry for SLC35C1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC35C1 gene promoter:
         c-Fos   CREB   AP-1   deltaCREB   LCR-F1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SLC35C1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC35C1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC35C1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p11.2   Ensembl cytogenetic band:  11p11.2   HGNC cytogenetic band: 11p11.2

SLC35C1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC35C1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P045826:  view genomic region     (about GC identifiers)

Start:
45,825,623 bp from pter      End:
45,834,567 bp from pter
Size:
8,945 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FUCT1_HUMAN, Q96A29 (See protein sequence)
Recommended Name: GDP-fucose transporter 1  
Size: 364 amino acids; 39809 Da
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAA92126.1; Type=Erroneous initiation;
Secondary accessions: B2RDB2 Q9BV76 Q9NUJ8
Alternative splicing: 2 isoforms:  Q96A29-1   Q96A29-2   

Explore the universe of human proteins at neXtProt for SLC35C1: NX_Q96A29

Explore proteomics data for SLC35C1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96A29

  • SLC35C1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SLC35C1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001138737.1  NP_001138738.1  NP_060859.4  

    ENSEMBL proteins: 
     ENSP00000412408   ENSP00000432145   ENSP00000313318   ENSP00000432669   ENSP00000399779  
    Reactome Protein details: Q96A29
    Human Recombinant Protein Products for SLC35C1: 
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    OriGene Protein Over-expression Lysate for SLC35C1
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    Novus Biologicals SLC35C1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    SLC35C1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SLC: Solute carriers

    IUPHAR Guide to PHARMACOLOGY protein family classification: GDP-Fucose transporter 
    SLC35 family of nucleotide sugar transporters

    2 InterPro protein domains:
     IPR004853 DUF250
     IPR000620 DMT

    Graphical View of Domain Structure for InterPro Entry Q96A29

    ProtoNet protein and cluster: Q96A29

    UniProtKB/Swiss-Prot: FUCT1_HUMAN, Q96A29
    Similarity: Belongs to the TPT transporter family. SLC35C subfamily


    SLC35C1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FUCT1_HUMAN, Q96A29
    Function: Involved in GDP-fucose import from the cytoplasm into the Golgi lumen

    Phenotypes:
         10 MGI mutant phenotypes (inferred from 1 allele(MGI details for Slc35c1):

     behavior/neurological  cellular  growth/size  hematopoietic system  homeostasis/metabolism 
     immune system  integument  mortality/aging  reproductive system  respiratory system 

    SLC35C1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Slc35c1tm1Cknr for SLC35C1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SLC35C1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SLC35C1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SLC35C1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLC35C1 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC35C1
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC35C1 (see all 18):
    hsa-miR-320a hsa-miR-125a-5p hsa-miR-331-3p hsa-miR-1271 hsa-miR-3154 hsa-miR-320e hsa-miR-125b hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmidSLC35C1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35C1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SLC35C1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1SLC-mediated transmembrane transport
    SLC-mediated transmembrane transport0.50
    Transmembrane transport of small molecules0.50
    2Transport of organic anions
    Transport of vitamins, nucleosides, and related molecules0.34
    3Transport of nucleotide sugars
    Transport of nucleotide sugars

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for SLC35C1
        SLC-mediated transmembrane transport
    Transmembrane transport of small molecules
    Transport of vitamins, nucleosides, and related molecules
    Transport of nucleotide sugars



    SLC35C1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC35C1

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008643carbohydrate transport IEA--
    GO:0030259lipid glycosylation IEA--
    GO:0045746negative regulation of Notch signaling pathway IEA--
    GO:0055085transmembrane transport TAS--
    GO:2000460regulation of eukaryotic cell surface binding ----

    SLC35C1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SLC35C1 (FUCT1)

    Search CenterWatch for drugs/clinical trials and news about SLC35C1 / FUCT1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SLC35C1 gene (3 alternative transcripts): 
    NM_001145265.1  NM_001145266.1  NM_018389.4  

    Unigene Cluster for SLC35C1:

    Solute carrier family 35, member C1
    Hs.12211  [show with all ESTs]
    Unigene Representative Sequence: NM_018389
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000442528 ENST00000526817 ENST00000314134(uc001nbp.3) ENST00000530471
    ENST00000456334(uc001nbo.3 uc010rgm.2)
    miRNA
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    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC35C1 (see all 18):
    hsa-miR-320a hsa-miR-125a-5p hsa-miR-331-3p hsa-miR-1271 hsa-miR-3154 hsa-miR-320e hsa-miR-125b hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmidSLC35C1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC35C1
    Clone
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    OriGene clones in human, mouse for SLC35C1 (see all 17)
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    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SLC35C1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC35C1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC35C1

    Additional mRNA sequence: 

    AF323970.1 AF326199.1 AK000527.1 AK002182.1 AK027394.1 AK027747.1 AK074929.1 AK091245.1 
    AK225428.1 AK315473.1 BC001427.2 

    7 DOTS entries:

    DT.40132519  DT.100823434  DT.102824574  DT.86852944  DT.92425634  DT.92032971  DT.97834850 

    24/164 AceView cDNA sequences (see all 164):

    AI246417 AA351081 BM712286 AK091245 AI245457 AL545993 AW297574 BI764766 
    BC001427 BM827143 CA488986 AA594606 BU737752 BP381612 AF323970 AA404618 
    CF126208 AU280041 AK000527 CR607230 Z40426 AK002182 AF326199 BM808157 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SLC35C1    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b
    SP1:        -     -                                       
    SP2:        -     -                                       
    SP3:                                                      
    SP4:                    -     -     -     -               


    ECgene alternative splicing isoforms for SLC35C1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SLC35C1 expression in normal human tissues (normalized intensities)      SLC35C1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCCAATCAG
    SLC35C1 Expression
    About this image


    SLC35C1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Neural Crest (Gastrulation Derivatives)
             skeleton/cranium   
     
     Bone (Gastrulation Derivatives)
             skeleton/cranium   
     
     Cartilage (Muscoskeletal System)
             skeleton/cranium   
     
     Neural Tube (Nervous System)
             Telencephalon
     
     Hair (Integumentary System)
             mouse/organ system/integumental system   

    See SLC35C1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SLC35C1

    SOURCE GeneReport for Unigene cluster: Hs.12211
        SABiosciences Custom PCR Arrays for SLC35C1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35C1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SLC35C1 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Slc35c11 , 5 solute carrier family 35, member C11, 5 85.4(n)1
    87.88(a)1
      2 (51.05 cM)5
    2283681  NM_211358.21  NP_997597.11 
     924527645 
    chicken
    (Gallus gallus)
    Aves SLC35C11 solute carrier family 35, member C1 77.41(n)
    77.41(a)
      423203  NM_001199651.1  NP_001186580.1 
    lizard
    (Anolis carolinensis)
    Reptilia SLC35C16
    Uncharacterized protein
    75(a)
    1 ↔ 1
    1(47772583-47779561)
    zebrafish
    (Danio rerio)
    Actinopterygii slc35c11 solute carrier family 35, member C1 67.48(n)
    70.82(a)
      494047  NM_001008590.1  NP_001008590.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Gfr1 CG9620-PA 57.99(n)
    52.06(a)
      40981  NM_141525.1  NP_649782.1 
    worm
    (Caenorhabditis elegans)
    Secernentea nstp-101 Protein NSTP-10 53.65(n)
    59.16(a)
      179342  NM_073066.4  NP_505467.2 


    ENSEMBL Gene Tree for SLC35C1 (if available)
    TreeFam Gene Tree for SLC35C1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/232 SNPs in SLC35C1 are shown (see all 232)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs289390871,2,4
    CCongenital disorder of glycosylation 2C (CDG2C)4 pathogenic145754348(+) TGGGCC/TGCTCA 6 R C mis1 ese30--------
    rs289378861,2,4
    CCongenital disorder of glycosylation 2C (CDG2C)4 pathogenic145759271(+) CCAGAC/GAGTGC 6 T R mis1 ese30--------
    rs797724791,2
    C,F--45750395(+) AAGACC/GTAAAA 2 -- us2k12Minor allele frequency- G:0.17CSA WA 120
    rs1156371541,2
    C,F--45750622(+) CAGAAT/CTTCAG 2 -- us2k11Minor allele frequency- C:0.02WA 118
    rs792610641,2
    C,F--45750643(+) AGAGAT/CTGGAG 2 -- us2k12Minor allele frequency- C:0.03NA 122
    rs1401086381,2
    --45750699(+) ACACAC/TGCAGC 2 -- us2k10--------
    rs750248931,2
    C,F--45750765(+) TATCTC/GTTCCC 2 -- us2k11Minor allele frequency- G:0.07WA 118
    rs1878031361,2
    --45750818(+) ATGTGC/GTAAGG 2 -- us2k10--------
    rs1437870731,2
    --45750911(+) CGGGCA/GTAAGA 2 -- us2k10--------
    rs1151982441,2
    C,F--45750999(+) ACTCTC/TCAGGT 2 -- us2k11Minor allele frequency- T:0.01WA 118

    HapMap Linkage Disequilibrium report for SLC35C1 (45825623 - 45834567 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SLC35C1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv897314CNV Loss21882294
    nsv897315CNV Loss21882294


    Human Gene Mutation Database (HGMD): SLC35C1

    Locus Specific Mutation Databases (LSDB): SLC35C1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SLC35C1
    DNA2.0 Custom Variant and Variant Library Synthesis for SLC35C1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605881   
    OMIM disorders: 266265  
    UniProtKB/Swiss-Prot: FUCT1_HUMAN, Q96A29
  • Congenital disorder of glycosylation 2C (CDG2C) [MIM:266265]: A multisystem disorder caused by a defect
    in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of
    glycosylation result in a wide variety of clinical features, such as defects in the nervous system development,
    psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad
    spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation,
    and maintenance of cell functions. The clinical features of CDG2C include mental retardation, short stature,
    facial stigmata, and recurrent bacterial peripheral infections with persistently elevated peripheral leukocytes.
    Biochemically, CDG2C is characterized by a lack of fucosylated glycoconjugates, including selectin ligands.
    Note=The disease is caused by mutations affecting the gene represented in this entry

  • 7 diseases for SLC35C1:    About MalaCards
    congenital disorder of glycosylation type 2c    leukocyte adhesion deficiency    congenital disorder of glycosylation    hypotonia
    short stature    mental retardation    hepatocellular carcinoma

    2 diseases from the University of Copenhagen DISEASES database for SLC35C1:
    Congenital disorder of glycosylation     Leukocyte adhesion deficiency

    SLC35C1 for disorders           About GeneDecksing

    GeneTests: SLC35C1
    GeneReviews: SLC35C1

    Export disorders for SLC35C1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SLC35C1 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with SLC35C1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter. (PubMed id 11326279)1, 2, 3 Luehn K.... Vestweber D. (2001)
    2. Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. (PubMed id 11326280)1, 2, 3 Lubke T....Korner C. (2001)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Identification of functional elements of the GDP-fucos e transporter SLC35C1 using a novel Chinese hamster ovary mutant. (PubMed id 22492235)1 Zhang P....Song Z. (2012)
    6. Hematologically important mutations: leukocyte adhesio n deficiency (first update). (PubMed id 22134107)1 van de Vijver E....Roos D. (2012)
    7. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
    8. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    9. A high expression of GDP-fucose transporter in hepatocellular carcinoma is a key factor for increases in fucosylation. (PubMed id 17884843)1 Moriwaki K....Miyoshi E. (2007)
    10. Leukocyte adhesion deficiency II patients with a dual defect of the GDP-fucose transporter. (PubMed id 16455955)1 Helmus Y....Wild M.K. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55343 HGNC: 20197 AceView: SLC35C1 Ensembl:ENSG00000181830 euGenes: HUgn55343
    ECgene: SLC35C1 H-InvDB: SLC35C1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SLC35C1 Pharmacogenomics, SNPs, Pathways
    SLC35C1basehttp://bioinf.uta.fi/SLC35C1base/
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SLC35C1
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SLC35C1 gene:
    Search GeneIP for patents involving SLC35C1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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