Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SLC35B4 Gene

protein-coding   GIFtS: 48
GCID: GC07M133974

solute carrier family 35, member B4

 Explore 2 diseases affiliated with
SLC35B4 via our new
 Human Malady Compendium 
Biological research products
for SLC35B4
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Solute Carrier Family 35, Member B41 2     YEA2
YEA41 2 3     UDP-Xylose And UDP-N-Acetylglucosamine Transporter2
YEA4 Homolog2 3     UDP-Xylose/N-Acetylglucosamine Transporter2
FLJ146971     Solute Carrier Family 35 Member B43

External Ids:    HGNC: 205841   Entrez Gene: 849122   Ensembl: ENSG000002050607   OMIM: 6109235   UniProtKB: Q969S03   

Export aliases for SLC35B4 gene to outside databases

Previous GC identifers: GC07M133377 GC07M133394 GC07M133435 GC07M133624 GC07M128275


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SLC35B4:
Glycosyltransferases, such as SLC35B4, transport nucleotide sugars from the cytoplasm where they are synthesized, to
the Golgi apparatus where they are utilized in the synthesis of glycoproteins, glycolipids, and proteoglycans (Ashikov
et al., 2005 (PubMed 15911612)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: S35B4_HUMAN, Q969S0
Function: Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and
UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi

Gene Wiki entry for SLC35B4


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SLC35B4 gene promoter:
         AML1a   FOXD3   CUTL1   GATA-1   GATA-2   PPAR-alpha   POU2F1   POU2F1a   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): SLC35B4 promoter sequence
   Search SABiosciences Chromatin IP Primers for SLC35B4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC35B4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q33   Ensembl cytogenetic band:  7q33   HGNC cytogenetic band: 7q33

SLC35B4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLC35B4 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M133974:  view genomic region     (about GC identifiers)

Start:
133,974,084 bp from pter      End:
134,001,827 bp from pter
Size:
27,744 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 133,318,463-133,346,213     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: S35B4_HUMAN, Q969S0 (See protein sequence)
Recommended Name: UDP-xylose and UDP-N-acetylglucosamine transporter  
Size: 331 amino acids; 37424 Da
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAB55325.1; Type=Erroneous initiation;
Secondary accessions: A4D1P3 A6NNS4 Q53GQ7 Q8TCU7 Q96K33
Alternative splicing: 3 isoforms:  Q969S0-1   Q969S0-2   Q969S0-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SLC35B4: NX_Q969S0

SLC35B4 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_116215.1  
ENSEMBL proteins: 
 ENSP00000367770   ENSP00000405445  
Reactome Protein details: Q969S0
Human Recombinant Protein Products: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
OriGene Custom Protein Services for SLC35B4 
GenScript Custom Purified and Recombinant Proteins Services for SLC35B4
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Uscn Proteins for SLC35B4

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000139Golgi membrane TAS--
GO:0005794Golgi apparatus IDA15911612
GO:0016021integral to membrane IEA--


SLC35B4 for ontologies           About GeneDecksing



SLC35B4 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for SLC35B4 
GenScript Custom Superior Antibodies Services for SLC35B4
Novus Biologicals SLC35B4 Antibody
Search for Antibodies for SLC35B4 at Abcam  
Uscn Antibodies for SLC35B4
ThermoFisher Antibodies for SLC35B4

Assay Products for SLC35B4: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Immunoassay Development
Browse OriGene Fluorogenic Cell Assay Kits
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for SLC35B4
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for SLC35B4


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SLC35B4 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR013657 UAA

Graphical View of Domain Structure for InterPro Entry Q969S0

ProtoNet protein and cluster: Q969S0

UniProtKB/Swiss-Prot: S35B4_HUMAN, Q969S0
Similarity: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

     UniProtKB/Swiss-Prot: S35B4_HUMAN, Q969S0
Function: Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and
UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi

miRNA
Products:
    
OriGene 3'-UTR Clone: SLC35B4
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC35B4
8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC35B4 (see all 29):
hsa-miR-30c hsa-miR-4311 hsa-miR-495 hsa-miR-30d hsa-miR-583 hsa-miR-30a hsa-miR-2116 hsa-miR-613
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC35B4 (see all 7)
OriGene shRNA RFP: SLC35B4
Browse OriGene siRNA
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC35B4

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for SLC35B4

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC35B4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC35B4
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: SLC35B4 (NM_032826)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC35B4
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC35B4 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for SLC35B4
Search LifeMap BioReagents cell lines for SLC35B4

In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35B4

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005462UDP-N-acetylglucosamine transmembrane transporter activity IDA15911612
GO:0005464UDP-xylose transmembrane transporter activity IDA15911612


SLC35B4 for ontologies           About GeneDecksing



(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1SLC-mediated transmembrane transport
SLC-mediated transmembrane transport1.00
Transmembrane transport of small molecules0.50
2Transport of nucleotide sugars
Transport of nucleotide sugars1.00
3Transport of organic anions
Transport of vitamins, nucleosides, and related molecules0.35

Pathway sources
See GeneCards unified pathways
Show all pathways


4        Reactome Pathways for SLC35B4
    SLC-mediated transmembrane transport
Transmembrane transport of small molecules
Transport of vitamins, nucleosides, and related molecules
Transport of nucleotide sugars



SLC35B4 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SLC35B4

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for SLC35B4 (Q969S03 ENSP000003677704) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
PDCD2Q163423, ENSP000001672184I2D: score=1 STRING: ENSP00000167218
DNAJA1P316893I2D: score=1 
About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008643carbohydrate transport IEA--
GO:0015788UDP-N-acetylglucosamine transport IDA15911612
GO:0015790UDP-xylose transport IDA15911612
GO:0055085transmembrane transport TAS--


SLC35B4 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SLC35B4
Search CenterWatch for drugs/clinical trials and news about SLC35B4 / S35B4 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SLC35B4 gene: 
NM_032826.4  

Unigene Cluster for SLC35B4:

Solute carrier family 35, member B4
Hs.490181  [show with all ESTs]
Unigene Representative Sequence: NM_032826
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000378509(uc003vrn.3 uc010lmk.3) ENST00000416907 ENST00000466599
ENST00000470969(uc003vro.4)

miRNA
Products:
     
OriGene 3'-UTR Clone: SLC35B4
Browse OriGene MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SLC35B4
8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate SLC35B4 (see all 29):
hsa-miR-30c hsa-miR-4311 hsa-miR-495 hsa-miR-30d hsa-miR-583 hsa-miR-30a hsa-miR-2116 hsa-miR-613
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC35B4 (see all 7)
OriGene shRNA RFP: SLC35B4
Browse OriGene siRNA
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC35B4
Clone
Products:
     
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC35B4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC35B4
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: SLC35B4 (NM_032826)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SLC35B4
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC35B4 
Primer
Products:
    
OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC35B4
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC35B4
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC35B4
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC35B4

Additional cDNA sequence: 

AB052892.1 AJ315497.1 AJ315498.1 AJ971941.1 AK027603.1 AK027726.1 AK056475.1 AK075368.1 
AK222874.1 AK307621.1 BC008413.1 

10 DOTS entries:

DT.404214  DT.442155  DT.100695906  DT.99934908  DT.121046842  DT.100749917  DT.95163286  DT.100749916 
DT.121046840  DT.95163287 

24/169 AceView cDNA sequences (see all 169):

BM706351 Z41039 AV651976 AI379300 AK027603 AI418933 CB135948 T19390 
AU184907 AJ315498 AA301392 AA464839 BP372821 AI360052 AV647046 AA837772 
AI422809 AA207198 AA252046 AA625377 BQ431120 AK075368 AK027726 BM720096 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SLC35B4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTTACTCAT

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image
See SLC35B4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SLC35B4

SOURCE GeneReport for Unigene cluster: Hs.490181
    SABiosciences Custom PCR Arrays for SLC35B4
Primer
Products:
OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC35B4
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SLC35B4
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC35B4
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC35B4
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35B4

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLC35B4 gene from 6/23 species (see all 23)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Slc35b41 , 5 solute carrier family 35, member B41, 5 88.92(n)1
90.94(a)1
  6 (14.75 cM)5
582461  NM_021435.31  NP_067410.11 
 341533805 
chicken
(Gallus gallus)
Aves SLC35B41 solute carrier family 35, member B4 76.67(n)
81.52(a)
  416698  XM_414994.3  XP_414994.1 
zebrafish
(Danio rerio)
Actinopterygii Dr.21872 Danio rerio mRNA similar to hypothetical protein, MNCb-4414 more 76.34(n)    BC045293.1 
fruit fly
(Drosophila melanogaster)
Insecta Efr1 ER GDP-fucose transporter 58.25(n)
54.89(a)
  31553  NM_132071.2  NP_572299.1 
worm
(Caenorhabditis elegans)
Secernentea nstp-21 Protein NSTP-2 50.75(n)
42.63(a)
  177424  NM_001047471.4  NP_001040936.1 
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YEA4(YEL004W)4
YEA41
Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) more4
Yea4p1
43.36(n)1
31.05(a)1
  5(146951-147979)4
8567141, 4  NP_010912.11, 4 


ENSEMBL Gene Tree for SLC35B4 (if available)
TreeFam Gene Tree for SLC35B4 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/528 NCBI SNPs in SLC35B4 are shown (see all 528    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1900761551,2
--133973732(+) CAAACC/TTCTAA 1 -- ds50010--------
rs1811510161,2
--133973878(+) CACCAC/TCACTA 1 -- ds50010--------
rs1857416031,2
--133973883(+) CCACTA/TTACAA 1 -- ds50010--------
rs1881073181,2
--133973966(+) GAAATG/TTATCA 1 -- ds50010--------
rs1405670501,2
C,--133974060(+) TCTAT-/AAGA  
        
AATAA
1 -- ds50010--------
rs30304451,2
C--133974062(+) TATAA-/GAAA  
        
TAATG
1 -- ds50011Minor allele frequency- GAAA:0.00NA 2
rs1403899181,2
--133974186(+) ACACAG/TCTCAA 1 -- ut310--------
rs1421184841,2
--133974345(+) CCACAA/TAATTT 1 -- ut310--------
rs81341,2
C,F,O,A,H,--133974519(-) ATAGAT/CGACTC 1 -- ut3128Minor allele frequency- C:0.46MN NA NS EA WA CSA 2864
rs1808400171,2
--133974628(+) CTCTGA/GCTCCC 1 -- ut310--------

HapMap Linkage Disequilibrium report for SLC35B4 (133974084 - 134001827 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for SLC35B4: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC35B4
DNA2.0 Custom Variant and Variant Library Synthesis for SLC35B4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SLC35B4 for disorders           About GeneDecksing

OMIM gene information: 610923    OMIM disorders: --

2 diseases for SLC35B4:    About MalaCards
t cell deficiency    obesity

Human Genome Epidemiology (HuGE) Navigator: SLC35B4 (2 documents)

Export disorders for SLC35B4 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for SLC35B4 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with SLC35B4)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP- N-acetylglucosamine. (PubMed id 15911612)1, 2 Ashikov A.... Bakker H. (2005)
  2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  5. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
  6. Deep congenic analysis identifies many strong, contex t-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeosta sis. (PubMed id 21507882)1 Yazbek S.N....Nadeau J.H. (2011)
  7. Subcellular localization of UDP-GlcNAc, UDP-Gal and SL C35B4 transporters. (PubMed id 21918738)1 Maszczak-Seneczko D....Olczak M. (2011)
  8. Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family. (PubMed id 16965264)1 Kobayashi T....Burchell B. (2006)
  9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  10. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 84912 HGNC: 20584 AceView: SLC35B4 Ensembl:ENSG00000205060 euGenes: HUgn84912
ECgene: SLC35B4 H-InvDB: SLC35B4

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for SLC35B4 Pharmacogenomics, SNPs, Pathways
GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for SLC35B4 gene:
Search GeneIP for patents involving SLC35B4

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
 Browse OriGene Antibodies   OriGene shRNA RFP for SLC35B4  
 OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SLC35B4   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SLC35B4  
 Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
 Browse OriGene siRNAs   OriGene 3'-UTR Clone for SLC35B4  
 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SLC35B4   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SLC35B4  
 Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
 Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
 Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for SLC35B4   OriGene Custom Protein Services for SLC35B4  
 OriGene Custom Immunoassay Development  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SLC35B4
 QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SLC35B4
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SLC35B4
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SLC35B4
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SLC35B4
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SLC35B4
 GenScript Custom Purified and Recombinant Proteins Services for SLC35B4 GenScript cDNA clones with any tag delivered in your preferred vector for SLC35B4
 GenScript Custom Assay Services for SLC35B4 GenScript Custom Superior Antibodies Services for SLC35B4
 GenScript Custom overexpressing Cell Line Services for SLC35B4 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in SLC35B4 promoter
 Search Chromatin IP Primers for SLC35B4
 RT2 qPCR Primer Assay in human, mouse, rat SLC35B4
 Search GNC Networks for SLC35B4
 SABiosciences Custom PCR Arrays for SLC35B4
 Search Tocris compounds for SLC35B4
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological cDNA Clones
 Antibodies/Proteins Production Services
 Rabbit Monoclonal Antibody Platform
 Bulk Purchasing
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 SLC35B4 antibodies
 Search for Antibodies for SLC35B4 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for SLC35B4
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 SLC35B4 Proteins, Antibodies, CLIAs, and ELISAs
 Search LifeMap BioReagents cell lines for SLC35B4
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLC35B4
 Browse SwitchGear 3'UTR luciferase reporter plasmids for SLC35B4
 SwitchGear Promoter luciferase reporter plasmids for SLC35B4
 ThermoFisher Antibodies for SLC35B4
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SLC35B4
       
GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category
VWF
(GIFTS: 73)
von Willebrand factor
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      SLC35B4 gene at Home site.
hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4