Aliases for SLC35A3 Gene
External Ids for SLC35A3 Gene
This gene encodes a UDP-N-acetylglucosamine transporter found in the golgi apparatus membrane. In cattle, a missense mutation in this gene causes complex vertebral malformation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
GeneCards Summary for SLC35A3 Gene
SLC35A3 (Solute Carrier Family 35 (UDP-N-Acetylglucosamine (UDP-GlcNAc) Transporter), Member A3) is a Protein Coding gene. Diseases associated with SLC35A3 include arthrogryposis, mental retardation, and seizures and autism spectrum disorder-epilepsy-arthrogryposis syndrome. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include sugar:proton symporter activity and UDP-N-acetylglucosamine transmembrane transporter activity. An important paralog of this gene is SLC35A5.
UniProtKB/Swiss-Prot for SLC35A3 Gene
Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter in the Golgi apparatus. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate branching of diantennary oligosaccharides.